JPWO2020023737A5 - - Google Patents

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JPWO2020023737A5
JPWO2020023737A5 JP2021503566A JP2021503566A JPWO2020023737A5 JP WO2020023737 A5 JPWO2020023737 A5 JP WO2020023737A5 JP 2021503566 A JP2021503566 A JP 2021503566A JP 2021503566 A JP2021503566 A JP 2021503566A JP WO2020023737 A5 JPWO2020023737 A5 JP WO2020023737A5
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certain embodiments
modified
seq
nucleobases
oligonucleotide
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JP2021503566A
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JP2021530241A (ja
JP7411632B2 (ja
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Priority to JP2023217671A priority Critical patent/JP2024038076A/ja
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JP2021503566A 2018-07-25 2019-07-25 Atxn2発現を低減するための化合物及び方法 Active JP7411632B2 (ja)

Priority Applications (1)

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JP2023217671A JP2024038076A (ja) 2018-07-25 2023-12-25 Atxn2発現を低減するための化合物及び方法

Applications Claiming Priority (3)

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US201862703240P 2018-07-25 2018-07-25
US62/703,240 2018-07-25
PCT/US2019/043424 WO2020023737A1 (en) 2018-07-25 2019-07-25 Compounds and methods for reducing atxn2 expression

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JP2023217671A Division JP2024038076A (ja) 2018-07-25 2023-12-25 Atxn2発現を低減するための化合物及び方法

Publications (3)

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JP2021530241A JP2021530241A (ja) 2021-11-11
JPWO2020023737A5 true JPWO2020023737A5 (de) 2022-08-15
JP7411632B2 JP7411632B2 (ja) 2024-01-11

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JP2021503566A Active JP7411632B2 (ja) 2018-07-25 2019-07-25 Atxn2発現を低減するための化合物及び方法
JP2023217671A Pending JP2024038076A (ja) 2018-07-25 2023-12-25 Atxn2発現を低減するための化合物及び方法

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US (2) US11078486B2 (de)
EP (1) EP3826645A4 (de)
JP (2) JP7411632B2 (de)
KR (1) KR20210038589A (de)
CN (1) CN112423767B (de)
AR (1) AR115847A1 (de)
AU (1) AU2019310097A1 (de)
BR (1) BR112021000308A2 (de)
CA (1) CA3106986A1 (de)
CL (1) CL2021000159A1 (de)
CO (1) CO2021000196A2 (de)
CR (1) CR20210100A (de)
EA (1) EA202190299A1 (de)
IL (1) IL280123A (de)
JO (1) JOP20210018A1 (de)
MX (1) MX2021000922A (de)
PE (1) PE20211398A1 (de)
PH (1) PH12021500007A1 (de)
SG (1) SG11202100077PA (de)
TW (1) TW202020154A (de)
UY (1) UY38316A (de)
WO (1) WO2020023737A1 (de)
ZA (1) ZA202100108B (de)

Families Citing this family (11)

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WO2015143246A1 (en) 2014-03-19 2015-09-24 Isis Pharmaceuticals, Inc. Compositions for modulating ataxin 2 expression
AU2015240761B2 (en) * 2014-04-01 2019-09-12 Biogen Ma Inc. Compositions for modulating SOD-1 expression
US20200283800A1 (en) * 2017-10-23 2020-09-10 Prevail Therapeutics, Inc. Gene therapies for neurodegenerative diseases
WO2019140231A1 (en) 2018-01-12 2019-07-18 Bristol-Myers Squibb Company Antisense oligonucleotides targeting alpha-synuclein and uses thereof
EP3826645A4 (de) 2018-07-25 2023-05-17 Ionis Pharmaceuticals, Inc. Verbindungen und verfahren zur verringerung der atxn2-expression
WO2021159008A2 (en) * 2020-02-07 2021-08-12 Maze Therapeutics, Inc. Compositions and methods for treating neurodegenerative diseases
CN115702243A (zh) * 2020-06-09 2023-02-14 罗氏创新中心哥本哈根有限公司 用于治疗性多核苷酸的鸟苷类似物
WO2023107893A2 (en) * 2021-12-06 2023-06-15 The Board Of Trustees Of The Leland Stanford Junior University Treatment of neuorodegenerative diseases through the inhibition of ataxin-2
WO2023239747A2 (en) * 2022-06-06 2023-12-14 University Of Utah Research Foundation Methods of modulating atxn2 expression
WO2023250368A2 (en) * 2022-06-24 2023-12-28 Eli Lilly And Company Atxn2 rna interference agents
WO2024056902A2 (en) * 2022-09-16 2024-03-21 Christopher Shaw Compositions and methods for treating neurological diseases

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