JPWO2020022475A5 - - Google Patents

Info

Publication number

JPWO2020022475A5

JPWO2020022475A5 JP2020532495A JP2020532495A JPWO2020022475A5 JP WO2020022475 A5 JPWO2020022475 A5 JP WO2020022475A5 JP 2020532495 A JP2020532495 A JP 2020532495A JP 2020532495 A JP2020532495 A JP 2020532495A JP WO2020022475 A5 JPWO2020022475 A5 JP WO2020022475A5

Authority

JP

Japan

Prior art keywords

amino acid

seq

acid sequence

antibody

sequence shown

Prior art date

2019-07-26

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

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• 125000003275 alpha amino acid group Chemical group 0.000 claims 78
• 150000001413 amino acids Chemical class 0.000 claims 28
• 102000004169 proteins and genes Human genes 0.000 claims 28
• 108090000623 proteins and genes Proteins 0.000 claims 28
• 229940079593 drug Drugs 0.000 claims 17
• 239000003814 drug Substances 0.000 claims 17
• 239000000611 antibody drug conjugate Substances 0.000 claims 14
• 229940049595 antibody-drug conjugate Drugs 0.000 claims 14
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
• 241000124008 Mammalia Species 0.000 claims 2
• 241000283973 Oryctolagus cuniculus Species 0.000 claims 1
• 239000000427 antigen Substances 0.000 claims 1
• 102000036639 antigens Human genes 0.000 claims 1
• 108091007433 antigens Proteins 0.000 claims 1
• 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
• 239000012634 fragment Substances 0.000 claims 1
• 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 claims 1
• 230000036470 plasma concentration Effects 0.000 claims 1