JPWO2019217527A5 - - Google Patents

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JPWO2019217527A5
JPWO2019217527A5 JP2020562569A JP2020562569A JPWO2019217527A5 JP WO2019217527 A5 JPWO2019217527 A5 JP WO2019217527A5 JP 2020562569 A JP2020562569 A JP 2020562569A JP 2020562569 A JP2020562569 A JP 2020562569A JP WO2019217527 A5 JPWO2019217527 A5 JP WO2019217527A5
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pharmaceutical composition
oligomer compound
disease
oligomer
nucleobase
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JP2020562569A
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JP2021522804A5 (https=
JP2021522804A (ja
JP7438135B2 (ja
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JP2020562569A 2018-05-09 2019-05-08 Fxiの発現を低下させるための化合物及び方法 Active JP7438135B2 (ja)

Priority Applications (1)

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JP2024019116A JP2024056830A (ja) 2018-05-09 2024-02-13 Fxiの発現を低下させるための化合物及び方法

Applications Claiming Priority (5)

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US201862669280P 2018-05-09 2018-05-09
US62/669,280 2018-05-09
US201862699572P 2018-07-17 2018-07-17
US62/699,572 2018-07-17
PCT/US2019/031277 WO2019217527A1 (en) 2018-05-09 2019-05-08 Compounds and methods for reducing fxi expression

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JP2021522804A JP2021522804A (ja) 2021-09-02
JP2021522804A5 JP2021522804A5 (https=) 2022-05-17
JPWO2019217527A5 true JPWO2019217527A5 (https=) 2022-05-17
JP7438135B2 JP7438135B2 (ja) 2024-02-26

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JP2020562569A Active JP7438135B2 (ja) 2018-05-09 2019-05-08 Fxiの発現を低下させるための化合物及び方法
JP2024019116A Withdrawn JP2024056830A (ja) 2018-05-09 2024-02-13 Fxiの発現を低下させるための化合物及び方法

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US (2) US20210355497A1 (https=)
EP (1) EP3799604A4 (https=)
JP (2) JP7438135B2 (https=)
KR (1) KR20210008498A (https=)
CN (1) CN112041446B (https=)
AU (1) AU2019266261A1 (https=)
BR (1) BR112020020957B1 (https=)
CA (1) CA3098136A1 (https=)
CL (2) CL2020002811A1 (https=)
CO (1) CO2020013942A2 (https=)
CR (1) CR20200605A (https=)
CU (1) CU20200082A7 (https=)
EC (1) ECSP20071129A (https=)
IL (1) IL277970B2 (https=)
JO (1) JOP20200280A1 (https=)
MX (1) MX2020011913A (https=)
MY (1) MY204000A (https=)
NI (1) NI202000079A (https=)
PE (1) PE20210393A1 (https=)
PH (1) PH12020551875A1 (https=)
SG (1) SG11202010012PA (https=)
TW (1) TWI853812B (https=)
WO (1) WO2019217527A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2011004097A (es) 2008-10-15 2011-07-28 Isis Pharmaceuticals Inc Modulacion de la expresion del factor 11.
CN115175685B (zh) 2019-12-09 2024-12-13 艾姆皮瑞克公司 用于治疗血管生成素样4(angptl4)相关疾病的寡核苷酸
JP2023554346A (ja) * 2020-12-18 2023-12-27 アイオーニス ファーマシューティカルズ, インコーポレーテッド 第xii因子を調節するための化合物及び方法
BR112023021231A2 (pt) 2021-04-13 2024-01-09 Sirnaomics Inc Produtos e composições
EP4493570A2 (en) 2022-03-16 2025-01-22 Empirico Inc. Galnac compositions for improving sirna bioavailability
KR20250080877A (ko) * 2022-09-26 2025-06-05 시리우스 테라퓨틱스, 인크. Fxi의 발현을 억제하기 위한 폴리핵산 분자, 약학 조성물, 및 이의 용도
WO2024140986A1 (zh) * 2022-12-30 2024-07-04 北京福元医药股份有限公司 用于抑制凝血因子xi基因表达的双链核糖核酸及其修饰物、缀合物和用途
UY40743A (es) * 2023-05-19 2024-12-13 Shanghai Argo Biopharmaceutical Co Ltd COMPOSICIONES Y MÉTODOS PARA INHIBIR LA EXPRESIÓN DEL factor de coagulación XI (FXI)
CN120173947A (zh) * 2024-03-28 2025-06-20 施能康医药科技(苏州)有限公司 靶向凝血因子xi的核酸及其用途

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