JPWO2016170106A5 - - Google Patents
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- Publication number
- JPWO2016170106A5 JPWO2016170106A5 JP2017555602A JP2017555602A JPWO2016170106A5 JP WO2016170106 A5 JPWO2016170106 A5 JP WO2016170106A5 JP 2017555602 A JP2017555602 A JP 2017555602A JP 2017555602 A JP2017555602 A JP 2017555602A JP WO2016170106 A5 JPWO2016170106 A5 JP WO2016170106A5
- Authority
- JP
- Japan
- Prior art keywords
- ambrox
- iii
- compounds
- selectively
- crystallizes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- YPZUZOLGGMJZJO-UHFFFAOYSA-N ambrofix Natural products C1CC2C(C)(C)CCCC2(C)C2C1(C)OCC2 YPZUZOLGGMJZJO-UHFFFAOYSA-N 0.000 description 7
- YPZUZOLGGMJZJO-LQKXBSAESA-N ambroxan Chemical compound CC([C@@H]1CC2)(C)CCC[C@]1(C)[C@@H]1[C@]2(C)OCC1 YPZUZOLGGMJZJO-LQKXBSAESA-N 0.000 description 7
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000006227 byproduct Chemical class 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000011143 downstream manufacturing Methods 0.000 description 1
- 238000010956 selective crystallization Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1507170.7 | 2015-04-24 | ||
| GBGB1507170.7A GB201507170D0 (en) | 2015-04-24 | 2015-04-24 | Process |
| PCT/EP2016/058997 WO2016170106A1 (en) | 2015-04-24 | 2016-04-22 | Process for isolating and purifying ambrox |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021011646A Division JP2021090423A (ja) | 2015-04-24 | 2021-01-28 | アンブロクスを単離および精製するためのプロセス |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2018513198A JP2018513198A (ja) | 2018-05-24 |
| JP2018513198A5 JP2018513198A5 (enExample) | 2020-09-10 |
| JPWO2016170106A5 true JPWO2016170106A5 (enExample) | 2023-01-06 |
| JP7246133B2 JP7246133B2 (ja) | 2023-03-27 |
Family
ID=53488739
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017555602A Active JP7246133B2 (ja) | 2015-04-24 | 2016-04-22 | アンブロクスを単離および精製するためのプロセス |
| JP2021011646A Pending JP2021090423A (ja) | 2015-04-24 | 2021-01-28 | アンブロクスを単離および精製するためのプロセス |
| JP2023057205A Active JP7690510B2 (ja) | 2015-04-24 | 2023-03-31 | アンブロクスを単離および精製するためのプロセス |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021011646A Pending JP2021090423A (ja) | 2015-04-24 | 2021-01-28 | アンブロクスを単離および精製するためのプロセス |
| JP2023057205A Active JP7690510B2 (ja) | 2015-04-24 | 2023-03-31 | アンブロクスを単離および精製するためのプロセス |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10294211B2 (enExample) |
| EP (1) | EP3286309B1 (enExample) |
| JP (3) | JP7246133B2 (enExample) |
| CN (1) | CN107548418B (enExample) |
| BR (1) | BR112017021789B1 (enExample) |
| CO (1) | CO2017010720A2 (enExample) |
| ES (1) | ES2856887T3 (enExample) |
| GB (1) | GB201507170D0 (enExample) |
| IL (1) | IL254836B2 (enExample) |
| MX (1) | MX381562B (enExample) |
| RU (1) | RU2720094C2 (enExample) |
| SG (1) | SG11201708085TA (enExample) |
| WO (1) | WO2016170106A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201507207D0 (en) | 2015-04-24 | 2015-06-10 | Givaudan Sa | Enzymes and applications thereof |
| GB201618090D0 (en) | 2016-10-26 | 2016-12-07 | Givaudan Sa | Product |
| WO2018157021A1 (en) * | 2017-02-24 | 2018-08-30 | International Flavors & Fragrances Inc. | Squalene hopene cyclase and use thereof for producing ambroxan |
| EP3677683B1 (en) * | 2017-09-01 | 2024-07-17 | Niigata University | Efficient method for producing ambrein |
| EP3476822A1 (en) | 2017-10-31 | 2019-05-01 | Givaudan SA | Process of making organic compounds |
| GB201917688D0 (en) | 2019-12-04 | 2020-01-15 | Givaudan Sa | SHC enzymes and enzyme variants |
| GB202011823D0 (en) * | 2020-07-30 | 2020-09-16 | Givaudan Sa | Method |
| GB202115120D0 (en) * | 2021-10-21 | 2021-12-08 | Givaudan Sa | Organic compounds |
| CN119876059A (zh) * | 2025-01-25 | 2025-04-25 | 天津大学浙江研究院(绍兴) | 一种降龙涎醚的生物催化合成方法 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU910561A1 (ru) * | 1980-08-19 | 1982-03-07 | Всесоюзный научно-исследовательский институт синтетических и натуральных душистых веществ | Способ получени смеси душистых веществ дитерпеноидного р да |
| SU1498767A1 (ru) * | 1987-06-04 | 1989-08-07 | Институт Химии Ан Мсср | Способ получени ( @ ) 3 @ ,6,6,9 @ -тетраметилпергидронафто [2,1-в]фурана |
| US5463089A (en) * | 1994-07-22 | 1995-10-31 | Quest International B.V. | Preparation of ambrox |
| DE19524584A1 (de) * | 1995-07-06 | 1997-01-09 | Basf Ag | Verfahren zur stereoselektiven Herstellung von (-)3a,6,6,9a-Tetramethyl-perhydronaphtho[2,1-b]furan |
| DE19649655A1 (de) | 1996-11-29 | 1998-06-04 | Haarmann & Reimer Gmbh | Syntheseenzyme für die Herstellung von Coniferylalkohol, Coniferylaldehyd, Ferulasäure, Vanillin und Vanillinsäure und deren Verwendung |
| JP3207172B2 (ja) | 1999-01-07 | 2001-09-10 | 科学技術振興事業団 | 光学活性環状化合物類の製造方法 |
| DE19960106A1 (de) | 1999-12-14 | 2001-06-21 | Haarmann & Reimer Gmbh | Enzyme und Gene für die Herstellung von Vanillin |
| AU2003302326A1 (en) | 2002-12-02 | 2004-08-10 | The Ohio State University Research Foundation | Rapid detection of microorganisms |
| US20040265850A1 (en) | 2002-12-02 | 2004-12-30 | Hua Wang | Rapid detection of microorganisms |
| CN100488940C (zh) * | 2004-06-11 | 2009-05-20 | 湖南中烟工业有限责任公司 | 用于制备降龙涎醚或向卷烟烟气释放降龙涎醚的草酸酯及应用 |
| WO2007015481A1 (ja) * | 2005-08-04 | 2007-02-08 | Shiseido Co., Ltd. | 香料成分の選定方法及び調香方法、嗜好性向上剤 |
| JP5236233B2 (ja) * | 2007-09-04 | 2013-07-17 | 花王株式会社 | （−）−アンブロキサンの製造方法 |
| KR101752514B1 (ko) | 2009-06-05 | 2017-06-29 | 바스프 에스이 | 소성 변형성 강성 폴리우레탄 발포체, 접착제 및 피복재를 함유하는 복합 부품 |
| EP2438182B1 (de) * | 2009-06-05 | 2018-10-10 | Basf Se | Biokatalytische herstellung von ambroxan |
| US8932839B2 (en) | 2010-11-17 | 2015-01-13 | Basf Se | Method for the biocatalytic cyclization of terpenes and cyclase mutants employable therein |
| ES2925777T3 (es) | 2010-11-17 | 2022-10-19 | Basf Se | Procedimiento para la ciclación biocatalítica de terpenos y mutantes de ciclasa que pueden usarse en el mismo |
| JP2013132226A (ja) | 2011-12-26 | 2013-07-08 | Kao Corp | （−）−３ａ，６，６，９ａ−テトラメチルドデカヒドロナフト［２，１−ｂ］フランの製造方法 |
| WO2013156398A1 (de) | 2012-04-16 | 2013-10-24 | Basf Se | Verbessertes verfahren zur herstellung von (3e, 7e)-homofarnesol |
| US20130273619A1 (en) | 2012-04-16 | 2013-10-17 | Basf Se | Process for the Preparation of (3E, 7E)-Homofarnesol |
| JP6429243B2 (ja) | 2013-09-05 | 2018-11-28 | 国立大学法人 新潟大学 | アンブレインの製造方法 |
| GB201318886D0 (en) | 2013-10-25 | 2013-12-11 | Givaudan Sa | Improvements i or relating to organic compounds |
| GB201318894D0 (en) | 2013-10-25 | 2013-12-11 | Givaudan Sa | Improvements in or relating to organic compounds |
| GB201507207D0 (en) * | 2015-04-24 | 2015-06-10 | Givaudan Sa | Enzymes and applications thereof |
| CN105037308B (zh) * | 2015-07-06 | 2017-06-06 | 四川中烟工业有限责任公司 | 一种制备降龙涎香醚的方法 |
-
2015
- 2015-04-24 GB GBGB1507170.7A patent/GB201507170D0/en not_active Ceased
-
2016
- 2016-04-22 RU RU2017134436A patent/RU2720094C2/ru active
- 2016-04-22 MX MX2017013100A patent/MX381562B/es unknown
- 2016-04-22 ES ES16718334T patent/ES2856887T3/es active Active
- 2016-04-22 SG SG11201708085TA patent/SG11201708085TA/en unknown
- 2016-04-22 CN CN201680023665.1A patent/CN107548418B/zh active Active
- 2016-04-22 EP EP16718334.2A patent/EP3286309B1/en active Active
- 2016-04-22 US US15/568,535 patent/US10294211B2/en active Active
- 2016-04-22 JP JP2017555602A patent/JP7246133B2/ja active Active
- 2016-04-22 WO PCT/EP2016/058997 patent/WO2016170106A1/en not_active Ceased
- 2016-04-22 BR BR112017021789-9A patent/BR112017021789B1/pt active IP Right Grant
-
2017
- 2017-10-02 IL IL254836A patent/IL254836B2/en unknown
- 2017-10-20 CO CONC2017/0010720A patent/CO2017010720A2/es unknown
-
2021
- 2021-01-28 JP JP2021011646A patent/JP2021090423A/ja active Pending
-
2023
- 2023-03-31 JP JP2023057205A patent/JP7690510B2/ja active Active
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