JPS6485928A - Monoclonal antibody and peptide useful for therapy and diagnosis for hiv infection - Google Patents

Monoclonal antibody and peptide useful for therapy and diagnosis for hiv infection

Info

Publication number
JPS6485928A
JPS6485928A JP62207336A JP20733687A JPS6485928A JP S6485928 A JPS6485928 A JP S6485928A JP 62207336 A JP62207336 A JP 62207336A JP 20733687 A JP20733687 A JP 20733687A JP S6485928 A JPS6485928 A JP S6485928A
Authority
JP
Japan
Prior art keywords
hiv
lavbru
monoclonal antibody
region
diagnosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62207336A
Other languages
English (en)
Japanese (ja)
Inventor
Kasuriin Shiyuraibuaa Marii
Kei Toomasu Erein
Eru Kosando Uesurii
Eichi Gosuteingu Rarii
Esu Deitsukinson Edona
Matsukuruua Jiyanera
Jiei Todaro Jiyooji
Shii Nouinsukii Robaato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetic Systems Corp
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Publication of JPS6485928A publication Critical patent/JPS6485928A/ja
Pending legal-status Critical Current

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04BPOSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B25/00Multi-stage pumps
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036Retroviridae, e.g. leukemia viruses
    • C07K16/1045Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1054Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16211Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • AIDS & HIV (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Mechanical Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP62207336A 1986-08-20 1987-08-20 Monoclonal antibody and peptide useful for therapy and diagnosis for hiv infection Pending JPS6485928A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89827386A 1986-08-20 1986-08-20
US4502687A 1987-05-01 1987-05-01
US6799687A 1987-06-29 1987-06-29

Publications (1)

Publication Number Publication Date
JPS6485928A true JPS6485928A (en) 1989-03-30

Family

ID=27366600

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62207336A Pending JPS6485928A (en) 1986-08-20 1987-08-20 Monoclonal antibody and peptide useful for therapy and diagnosis for hiv infection

Country Status (28)

Country Link
JP (1) JPS6485928A (el)
KR (1) KR920008744B1 (el)
AT (1) AT398080B (el)
AU (1) AU616156B2 (el)
BE (1) BE1000811A4 (el)
CH (1) CH675728A5 (el)
CS (1) CS275838B6 (el)
DE (1) DE3727703A1 (el)
DK (1) DK433087A (el)
ES (1) ES2010727A6 (el)
FI (1) FI873553A (el)
FR (1) FR2603107B1 (el)
GB (1) GB2196634B (el)
GR (1) GR871298B (el)
HU (1) HU214439B (el)
IE (1) IE60671B1 (el)
IL (1) IL83580A (el)
IT (1) IT1222518B (el)
LU (1) LU86972A1 (el)
NL (1) NL8701950A (el)
NO (2) NO300462B1 (el)
NZ (1) NZ221440A (el)
OA (1) OA08652A (el)
PL (1) PL155084B1 (el)
PT (1) PT85567B (el)
SE (1) SE506025C2 (el)
YU (1) YU152587A (el)
ZW (1) ZW15487A1 (el)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03503166A (ja) * 1988-01-26 1991-07-18 アメリカ合衆国 抗hiv応答を喚起する合成抗原
JPH03504556A (ja) * 1987-05-29 1991-10-09 タノツクス・バイオシステムズ・インコーポレーテツド Hiv‐1を中和するモノクローナル抗体
JPH04243895A (ja) * 1990-07-19 1992-08-31 Merck & Co Inc 環状hiv主中和決定基ペプチド
JPH04243896A (ja) * 1990-07-19 1992-08-31 Merck & Co Inc 環状のhiv主要中和決定基ペプチド
JPH05310785A (ja) * 1991-09-30 1993-11-22 Nitto Denko Corp Hiv関連環状ペプチドおよびこれを固定化した吸着体
WO2010026940A1 (ja) 2008-09-02 2010-03-11 日本特殊陶業株式会社 スパークプラグ

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP96A (en) * 1986-06-03 1990-08-12 The Usa Dept Of Commerce Small peptides which inhibit binding to T-4 receptors and act as immunogens.
AU625720B2 (en) * 1987-05-01 1992-07-16 Genetic Systems Corporation Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use
US5834599A (en) * 1987-05-29 1998-11-10 Tanox Biosystems, Inc. Immunoconjugates which neutralize HIV-1 infection
US6657050B1 (en) 1987-05-29 2003-12-02 Tanox, Inc. Chimeric viral-neutralizing immunoglobulins
US5981278A (en) * 1987-05-29 1999-11-09 Tanox, Inc. Chimeric monoclonal antibodies which neutralize HIV-1 infection and their applications in therapy and prevention for AIDS
CA1341285C (en) * 1988-02-12 2001-08-14 Chang Yi Wang Synthetic peptides for the detection of antibodies to hiv gp120 envelope protein for diagnosis of aids and pre-aids conditions and as vaccines
IL90048A0 (en) * 1988-04-25 1989-12-15 Merck & Co Inc Recombinant gag precursor of hiv,its preparation and its use as aids vaccine
EP0339504A3 (en) * 1988-04-26 1990-09-12 The Du Pont Merck Pharmaceutical Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
US5562905A (en) * 1988-04-26 1996-10-08 E. I. Du Pont De Nemours And Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
FR2632310B1 (fr) * 1988-06-06 1992-04-10 Pasteur Institut Peptides ayant des proprietes protectrices d'un virus pathogene du type hiv dans des cellules sensibles
AU640619B2 (en) * 1988-10-03 1993-09-02 Repligen Corporation Hiv proteins and peptides useful in the diagnosis, prophylaxis or therapy of aids
CA2025481A1 (en) * 1989-09-19 1991-03-20 Peter J. Kniskern Vaccine for aids and hepatitis b
SE9000333D0 (sv) * 1990-01-31 1990-01-31 Britta Wahren Monoklonal antikropp
SE468168B (sv) * 1990-02-20 1992-11-16 Replico Medical Ab Hiv-1, p24 peptider, diagnostiska antigener och foerfarande foer saerskiljande diagnostik av preliminaert hiv-1 positiva serumprov
JPH03271233A (ja) * 1990-03-19 1991-12-03 Inst Pasteur ウイルスエンベロープ糖タンパク質及びその糖タンパク質の中和エピトープに対応するペプチドの間の相乗作用による、ウイルス性感染に対する防御の誘発
ATE267838T1 (de) * 1992-03-27 2004-06-15 Advanced Immuni T Inc T-peptid und damit verwandte peptide in der behandlung von entzündungen einschlies slich der multiplen sklerose
US8470778B2 (en) * 2005-12-09 2013-06-25 Vectus Biosystems Limited VIP fragments and methods of use

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9328391B1 (en) * 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
GB8501473D0 (en) * 1985-01-21 1985-02-20 Pasteur Institut Cloned dna sequences
DE3588248T2 (de) * 1984-10-18 2004-07-01 Institut Pasteur LAV-Antigene und -Peptide
CA1341482C (en) * 1984-10-31 2005-05-10 Paul A. Luciw Process for preparing fragments of aids-associated retroviruses
IE64785B1 (en) * 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
WO1986006099A1 (en) * 1985-04-08 1986-10-23 Genetic Systems Corporation EXPRESSION AND DIAGNOSTIC USE OF gag ENCODED PEPTIDES WHICH ARE IMMUNOLOGICALLY REACTIVE WITH ANTIBODIES TO LAV
FI861626A (fi) * 1985-04-19 1986-10-20 Hoffmann La Roche Foervaervat immunbristsyndrom (aids) -relaterat viralt rekombinant hoeljeprotein samt ett testfoerfarande foer aids.
DE3650175T3 (de) * 1985-04-29 2007-09-06 Bio-Rad Laboratories, Inc., Hercules Synthetische antigene zum nachweis von aids.
GB8525615D0 (en) * 1985-10-17 1985-11-20 Hoffmann La Roche Polypeptides
WO1987002775A1 (en) * 1985-10-24 1987-05-07 Southwest Foundation For Biomedical Research Synthetic peptides and use for diagnosis and vaccination for aids and arc
EP0245459B1 (en) * 1985-11-07 1993-09-29 The President And Fellows Of Harvard College T-cell lymphotrophic virus protein and assay
US4772547A (en) * 1986-02-03 1988-09-20 Hoffmann-La Roche Inc. HTLV-III envelope peptides
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
US4925784A (en) * 1986-04-04 1990-05-15 Hoffmann-La Roche Inc. Expression and purification of an HTLV-III gag/env gene protein
IE63109B1 (en) * 1986-06-23 1995-03-22 Genetic Systems Corp Human monoclonal antibody to lymphadenopathy-associated virus
EP0525828A3 (en) * 1986-08-01 1993-02-24 Repligen Corporation Recombinant polypeptides and their uses, including assay for aids virus
EP0273716B1 (en) * 1986-12-30 1993-08-11 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Synthetic peptides which induce cellular immunity to the aids virus and aids viral proteins

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03504556A (ja) * 1987-05-29 1991-10-09 タノツクス・バイオシステムズ・インコーポレーテツド Hiv‐1を中和するモノクローナル抗体
JPH03503166A (ja) * 1988-01-26 1991-07-18 アメリカ合衆国 抗hiv応答を喚起する合成抗原
JPH04243895A (ja) * 1990-07-19 1992-08-31 Merck & Co Inc 環状hiv主中和決定基ペプチド
JPH04243896A (ja) * 1990-07-19 1992-08-31 Merck & Co Inc 環状のhiv主要中和決定基ペプチド
JPH05310785A (ja) * 1991-09-30 1993-11-22 Nitto Denko Corp Hiv関連環状ペプチドおよびこれを固定化した吸着体
WO2010026940A1 (ja) 2008-09-02 2010-03-11 日本特殊陶業株式会社 スパークプラグ

Also Published As

Publication number Publication date
FI873553A (fi) 1988-02-21
PT85567B (pt) 1991-02-08
CH675728A5 (el) 1990-10-31
SE8703225L (sv) 1988-02-21
NL8701950A (nl) 1988-03-16
SE8703225D0 (sv) 1987-08-19
NO934897L (no) 1993-12-29
FI873553A0 (fi) 1987-08-17
YU152587A (sh) 1992-09-07
NO934897D0 (no) 1993-12-29
NO300462B1 (no) 1997-06-02
IL83580A0 (en) 1988-01-31
LU86972A1 (fr) 1988-03-02
NZ221440A (en) 1991-11-26
FR2603107B1 (fr) 1992-04-24
OA08652A (fr) 1988-11-30
GB8719587D0 (en) 1987-09-23
HU214439B (hu) 1998-03-30
AT398080B (de) 1994-09-26
DK433087A (da) 1988-02-21
BE1000811A4 (fr) 1989-04-11
NO873495L (no) 1988-02-22
GB2196634A (en) 1988-05-05
CS8706136A2 (en) 1990-08-14
DE3727703A1 (de) 1988-05-05
AU7720187A (en) 1988-05-19
GB2196634B (en) 1991-05-15
KR920008744B1 (ko) 1992-10-09
ATA208987A (de) 1994-01-15
KR890002547A (ko) 1989-04-10
CS275838B6 (en) 1992-03-18
NO873495D0 (no) 1987-08-19
HUT44619A (en) 1988-03-28
PT85567A (en) 1987-09-01
IL83580A (en) 1992-11-15
IE872219L (en) 1988-02-20
ZW15487A1 (en) 1988-09-14
SE506025C2 (sv) 1997-11-03
IE60671B1 (en) 1994-08-10
FR2603107A1 (fr) 1988-02-26
AU616156B2 (en) 1991-10-24
NO302176B1 (no) 1998-02-02
ES2010727A6 (es) 1989-12-01
IT8721678A0 (it) 1987-08-19
PL267401A1 (en) 1988-07-21
DK433087D0 (da) 1987-08-19
GR871298B (en) 1988-01-12
PL155084B1 (en) 1991-10-31
IT1222518B (it) 1990-09-05

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