ATE267838T1 - T-peptid und damit verwandte peptide in der behandlung von entzündungen einschlies slich der multiplen sklerose - Google Patents

T-peptid und damit verwandte peptide in der behandlung von entzündungen einschlies slich der multiplen sklerose

Info

Publication number
ATE267838T1
ATE267838T1 AT99101349T AT99101349T ATE267838T1 AT E267838 T1 ATE267838 T1 AT E267838T1 AT 99101349 T AT99101349 T AT 99101349T AT 99101349 T AT99101349 T AT 99101349T AT E267838 T1 ATE267838 T1 AT E267838T1
Authority
AT
Austria
Prior art keywords
absent
thr
ser
gly
treatment
Prior art date
Application number
AT99101349T
Other languages
English (en)
Inventor
Anders Jorgen Andersen
Roger Aston
Peter Louis Carlen
Penelope Reed Doob
David James Phipps
Douglas Kevin Macfadden
Deborah Rathjen
Fred Widmer
Original Assignee
Advanced Immuni T Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK92645A external-priority patent/DK64592D0/da
Application filed by Advanced Immuni T Inc filed Critical Advanced Immuni T Inc
Application granted granted Critical
Publication of ATE267838T1 publication Critical patent/ATE267838T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/549Sugars, nucleosides, nucleotides or nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT99101349T 1992-03-27 1993-03-29 T-peptid und damit verwandte peptide in der behandlung von entzündungen einschlies slich der multiplen sklerose ATE267838T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85883292A 1992-03-27 1992-03-27
DK92645A DK64592D0 (da) 1992-05-14 1992-05-14 Peptider til terapeutisk behandling
US91511892A 1992-07-17 1992-07-17
US98767492A 1992-12-09 1992-12-09

Publications (1)

Publication Number Publication Date
ATE267838T1 true ATE267838T1 (de) 2004-06-15

Family

ID=27439352

Family Applications (2)

Application Number Title Priority Date Filing Date
AT93907942T ATE194495T1 (de) 1992-03-27 1993-03-29 T-peptid und damit verwandte peptide in der behandlung von entzündungen einschliesslich der multiplen sklerose
AT99101349T ATE267838T1 (de) 1992-03-27 1993-03-29 T-peptid und damit verwandte peptide in der behandlung von entzündungen einschlies slich der multiplen sklerose

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT93907942T ATE194495T1 (de) 1992-03-27 1993-03-29 T-peptid und damit verwandte peptide in der behandlung von entzündungen einschliesslich der multiplen sklerose

Country Status (12)

Country Link
EP (2) EP0960886B1 (de)
JP (1) JP3520084B2 (de)
KR (1) KR100312300B1 (de)
AT (2) ATE194495T1 (de)
AU (3) AU684713B2 (de)
CA (1) CA2132516A1 (de)
DE (2) DE69333537T2 (de)
DK (2) DK0960886T3 (de)
ES (2) ES2222625T3 (de)
PT (1) PT960886E (de)
UA (1) UA41881C2 (de)
WO (1) WO1993020102A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5739109A (en) * 1988-12-16 1998-04-14 Advanced Immunit Inc. Method of treating neuroinflammatory degenerative diseases
WO1995008338A1 (en) * 1993-09-24 1995-03-30 Peptide Technology Limited Method for the treatment or prevention of eczema/dermatitis
DE69433817T2 (de) * 1993-09-24 2005-07-14 Advanced Immuni T, Inc. Lineare und cyklische peptide zur behandlung oder vorbeugung der crohn'schen krankheit und/oder der ulzerativen kolitis
KR20020063182A (ko) * 1999-11-09 2002-08-01 어드밴스드 임뮤니 티, 인코포래이티드 펩티드 t의 투여를 통해 초기 유전자 발현을변경시킴으로써 바이러스 질환 및 기타 장애를 치료하는방법
JP4611233B2 (ja) * 2005-04-06 2011-01-12 ニッタ株式会社 歩行訓練支援装置
US10501494B2 (en) * 2013-04-26 2019-12-10 Creative Bio-Peptides Uses of peptides to treat brain injury and disease
EP2832373B1 (de) * 2013-08-02 2017-04-12 Experimentelle Pharmakologie & Onkologie Berlin Buch Liposom zur Blockierung eines standortspezifischen chemokinassoziierten entzündlichen Prozesses bei Gefäßerkrankungen und Metastasen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987007614A1 (en) * 1986-06-03 1987-12-17 Pert Candace B Small peptides which inhibit binding to t-4 receptors
NZ221440A (en) * 1986-08-20 1991-11-26 Genetic Systems Corp Composition containing monoclonal antibodies/peptides useful in treating and diagnosing hiv infections
AU1808088A (en) * 1987-05-22 1988-12-21 Syntbiotech, Inc. Synthetic peptides and a method of treating aids
US5189022A (en) * 1988-05-27 1993-02-23 The United States Of America As Represented By The Secretary Of Health And Human Services Composition for the treatment of chronic fatigue syndrome
WO1989012067A1 (en) * 1988-05-27 1989-12-14 The United States Of America, As Represented By Th Compositions having use as treatment of psoriasis and neuropsychiatric deficits

Also Published As

Publication number Publication date
AU718442B2 (en) 2000-04-13
EP0635027A1 (de) 1995-01-25
EP0960886B1 (de) 2004-05-26
UA41881C2 (uk) 2001-10-15
ES2222625T3 (es) 2005-02-01
KR950700931A (ko) 1995-02-20
PT960886E (pt) 2004-10-29
EP0960886A1 (de) 1999-12-01
AU684713B2 (en) 1998-01-08
DE69329023T2 (de) 2001-03-22
AU725680B2 (en) 2000-10-19
DE69333537D1 (de) 2004-07-01
ES2149203T3 (es) 2000-11-01
AU3895393A (en) 1993-11-08
CA2132516A1 (en) 1993-10-14
EP0635027B1 (de) 2000-07-12
JP3520084B2 (ja) 2004-04-19
DK0960886T3 (da) 2004-09-27
DE69333537T2 (de) 2005-06-16
JPH07507061A (ja) 1995-08-03
KR100312300B1 (ko) 2002-03-20
AU2254999A (en) 1999-05-20
ATE194495T1 (de) 2000-07-15
WO1993020102A1 (en) 1993-10-14
DK0635027T3 (da) 2000-10-02
AU6354298A (en) 1998-06-18
DE69329023D1 (de) 2000-08-17

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