AU616156B2 - Monoclonal antibodies and peptides useful in treating and diagnosing HIV infections - Google Patents

Monoclonal antibodies and peptides useful in treating and diagnosing HIV infections

Info

Publication number
AU616156B2
AU616156B2 AU77201/87A AU7720187A AU616156B2 AU 616156 B2 AU616156 B2 AU 616156B2 AU 77201/87 A AU77201/87 A AU 77201/87A AU 7720187 A AU7720187 A AU 7720187A AU 616156 B2 AU616156 B2 AU 616156B2
Authority
AU
Australia
Prior art keywords
treating
monoclonal antibodies
hiv infections
peptides useful
diagnosing hiv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU77201/87A
Other versions
AU7720187A (en
Inventor
Wesley L. Cosand
Edna S. Dickinson
Larry H. Gosting
Janela Mcclure
Robert C. Nowinski
Mary Kathleen Shriver
Elaine K. Thomas
George J. Todaro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetic Systems Corp
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Publication of AU7720187A publication Critical patent/AU7720187A/en
Application granted granted Critical
Publication of AU616156B2 publication Critical patent/AU616156B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B25/00—Multi-stage pumps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1054—Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
AU77201/87A 1986-08-20 1987-08-19 Monoclonal antibodies and peptides useful in treating and diagnosing HIV infections Ceased AU616156B2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US89827386A 1986-08-20 1986-08-20
US4502687A 1987-05-01 1987-05-01
US045026 1987-05-01
US6799687A 1987-06-29 1987-06-29
US067996 1987-06-29
US898273 1992-06-15

Publications (2)

Publication Number Publication Date
AU7720187A AU7720187A (en) 1988-05-19
AU616156B2 true AU616156B2 (en) 1991-10-24

Family

ID=27366600

Family Applications (1)

Application Number Title Priority Date Filing Date
AU77201/87A Ceased AU616156B2 (en) 1986-08-20 1987-08-19 Monoclonal antibodies and peptides useful in treating and diagnosing HIV infections

Country Status (28)

Country Link
JP (1) JPS6485928A (en)
KR (1) KR920008744B1 (en)
AT (1) AT398080B (en)
AU (1) AU616156B2 (en)
BE (1) BE1000811A4 (en)
CH (1) CH675728A5 (en)
CS (1) CS275838B6 (en)
DE (1) DE3727703A1 (en)
DK (1) DK433087A (en)
ES (1) ES2010727A6 (en)
FI (1) FI873553A (en)
FR (1) FR2603107B1 (en)
GB (1) GB2196634B (en)
GR (1) GR871298B (en)
HU (1) HU214439B (en)
IE (1) IE60671B1 (en)
IL (1) IL83580A (en)
IT (1) IT1222518B (en)
LU (1) LU86972A1 (en)
NL (1) NL8701950A (en)
NO (2) NO300462B1 (en)
NZ (1) NZ221440A (en)
OA (1) OA08652A (en)
PL (1) PL155084B1 (en)
PT (1) PT85567B (en)
SE (1) SE506025C2 (en)
YU (1) YU152587A (en)
ZW (1) ZW15487A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP96A (en) * 1986-06-03 1990-08-12 The Usa Dept Of Commerce Small peptides which inhibit binding to T-4 receptors and act as immunogens.
AU625720B2 (en) * 1987-05-01 1992-07-16 Genetic Systems Corporation Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use
WO1988009181A2 (en) * 1987-05-29 1988-12-01 Tanox Biosystems, Inc. Monoclonal antibodies neutralizing hiv-1
US5834599A (en) * 1987-05-29 1998-11-10 Tanox Biosystems, Inc. Immunoconjugates which neutralize HIV-1 infection
US5981278A (en) * 1987-05-29 1999-11-09 Tanox, Inc. Chimeric monoclonal antibodies which neutralize HIV-1 infection and their applications in therapy and prevention for AIDS
US6657050B1 (en) 1987-05-29 2003-12-02 Tanox, Inc. Chimeric viral-neutralizing immunoglobulins
DE68926499T2 (en) * 1988-01-26 1996-12-19 Us Health SYNTHETIC ANTIQUE TO AFFECT AN ANTI-HIV REACTION
CA1341285C (en) * 1988-02-12 2001-08-14 Chang Yi Wang Synthetic peptides for the detection of antibodies to hiv gp120 envelope protein for diagnosis of aids and pre-aids conditions and as vaccines
IL90048A0 (en) * 1988-04-25 1989-12-15 Merck & Co Inc Recombinant gag precursor of hiv,its preparation and its use as aids vaccine
US5562905A (en) * 1988-04-26 1996-10-08 E. I. Du Pont De Nemours And Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
EP0339504A3 (en) * 1988-04-26 1990-09-12 The Du Pont Merck Pharmaceutical Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
FR2632310B1 (en) * 1988-06-06 1992-04-10 Pasteur Institut PEPTIDES HAVING PROTECTIVE PROPERTIES OF A PATHOGENIC VIRUS OF THE HIV TYPE IN SENSITIVE CELLS
KR900701836A (en) * 1988-10-03 1990-12-04 라메쉬 엘. 라탄 Peptides useful for diagnosing, preventing or treating new HIV proteins and AIDS
CA2025481A1 (en) * 1989-09-19 1991-03-20 Peter J. Kniskern Vaccine for aids and hepatitis b
SE9000333D0 (en) * 1990-01-31 1990-01-31 Britta Wahren MONOCLONAL ANTIBODY
SE468168B (en) * 1990-02-20 1992-11-16 Replico Medical Ab HIV-1, P24 PEPTIDES, DIAGNOSTIC ANTIGENS AND PROCEDURES FOR DIFFERENTIAL DIAGNOSTICS OF PRELIMINARY HIV-1 POSITIVE SERUM TESTS
JPH03271233A (en) * 1990-03-19 1991-12-03 Inst Pasteur Inducement of protective action against virus infection by synergism between peptides cor- responding to virus envelope glycoprotein and neutral epitope of its glycoprotein
CA2047078A1 (en) * 1990-07-19 1992-01-20 Steven S. Bondy Cyclic hiv principal neutralizing determinant peptides
CA2047042A1 (en) * 1990-07-19 1992-01-20 John Hannah Cyclic hiv principal neutralizing determinant peptides
JPH05310785A (en) * 1991-09-30 1993-11-22 Nitto Denko Corp Hiv-related cyclic peptide and adsorption material obtained by immobilizing the same
ATE267838T1 (en) * 1992-03-27 2004-06-15 Advanced Immuni T Inc T-PEPTIDE AND RELATED PEPTIDES IN THE TREATMENT OF INFLAMMATION INCLUDING MULTIPLE SCLEROSIS
JP5449778B2 (en) * 2005-12-09 2014-03-19 ベクタス・バイオシステムズ・リミテッド VIP fragments and methods of use
CN102138260B (en) 2008-09-02 2013-07-31 日本特殊陶业株式会社 Spark plug

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5572786A (en) * 1985-04-08 1986-10-16 Genetic Systems Corporation Expression of immunologically reactive aids viral protein
AU7081987A (en) * 1986-02-03 1987-08-25 Cambridge Bioscience Corporation Peptides for the diagnosis of htlv-iii antibodies, their preparation and use
AU7635887A (en) * 1986-08-01 1988-02-04 Repligen Corporation Recombinant HTLV-III proteins and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9328391B1 (en) * 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
GB8501473D0 (en) * 1985-01-21 1985-02-20 Pasteur Institut Cloned dna sequences
EP0201540B2 (en) * 1984-10-18 2001-10-31 Institut Pasteur Envelope antigens of lymphadenopathy associated virus and their applications
CA1341423C (en) * 1984-10-31 2003-03-04 Paul A. Luciw Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome
GR860915B (en) * 1985-04-08 1986-07-11 Genetic Systems Corp Expression and diagnostic use of gag encoded peptides which are immunologically reactive with antibodies to lav
DK171119B1 (en) * 1985-04-19 1996-06-17 Hoffmann La Roche AIDS virus envelope protein, expression vector carrying the envelope protein, transformants transformed with the expression vector, method of producing the virus envelope protein, method of detecting AIDS antibodies, method of determining AIDS virus, vaccine against AIDS, antibodies against the virus envelope protein and use of it to prepare a vaccine and for testing
KR910002374B1 (en) * 1985-04-29 1991-04-20 제네틱 시스템즈 코포레이션 Synthetic antigens for the detection of aids-relate disease
GB8525615D0 (en) * 1985-10-17 1985-11-20 Hoffmann La Roche Polypeptides
WO1987002775A1 (en) * 1985-10-24 1987-05-07 Southwest Foundation For Biomedical Research Synthetic peptides and use for diagnosis and vaccination for aids and arc
JP2837669B2 (en) * 1985-11-07 1998-12-16 プレジデント アンド フエロウズ オブ ハ−バ−ド カレツジ T-cell lymphotropic virus protein and its analysis
US4772547A (en) * 1986-02-03 1988-09-20 Hoffmann-La Roche Inc. HTLV-III envelope peptides
US4925784A (en) * 1986-04-04 1990-05-15 Hoffmann-La Roche Inc. Expression and purification of an HTLV-III gag/env gene protein
DK169582B1 (en) * 1986-06-23 1994-12-12 Squibb Bristol Myers Co Human monoclonal antibody capable of reacting with an epitope on the LAV / HTLV-III envelope glycoprotein gp41, cell lines producing such antibody, pharmaceutical preparation containing the antibody, and method for determining the presence of LAV / HTLV-III in a biological sample. and method for separating specific antigenic determinants of LAV / HTLV-III using ant
AU592258B2 (en) * 1986-12-30 1990-01-04 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Synthetic peptides which induce cellular immunity to the aids virus and aids viral proteins

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5572786A (en) * 1985-04-08 1986-10-16 Genetic Systems Corporation Expression of immunologically reactive aids viral protein
AU7081987A (en) * 1986-02-03 1987-08-25 Cambridge Bioscience Corporation Peptides for the diagnosis of htlv-iii antibodies, their preparation and use
AU7635887A (en) * 1986-08-01 1988-02-04 Repligen Corporation Recombinant HTLV-III proteins and uses thereof

Also Published As

Publication number Publication date
DE3727703A1 (en) 1988-05-05
GR871298B (en) 1988-01-12
NO873495D0 (en) 1987-08-19
AT398080B (en) 1994-09-26
GB8719587D0 (en) 1987-09-23
IE60671B1 (en) 1994-08-10
PT85567A (en) 1987-09-01
FR2603107A1 (en) 1988-02-26
ATA208987A (en) 1994-01-15
IL83580A (en) 1992-11-15
CS275838B6 (en) 1992-03-18
AU7720187A (en) 1988-05-19
JPS6485928A (en) 1989-03-30
NO934897L (en) 1993-12-29
FR2603107B1 (en) 1992-04-24
CS8706136A2 (en) 1990-08-14
NO934897D0 (en) 1993-12-29
FI873553A0 (en) 1987-08-17
LU86972A1 (en) 1988-03-02
DK433087D0 (en) 1987-08-19
NO300462B1 (en) 1997-06-02
DK433087A (en) 1988-02-21
IL83580A0 (en) 1988-01-31
PL267401A1 (en) 1988-07-21
NO873495L (en) 1988-02-22
ZW15487A1 (en) 1988-09-14
SE8703225L (en) 1988-02-21
OA08652A (en) 1988-11-30
IE872219L (en) 1988-02-20
IT1222518B (en) 1990-09-05
PL155084B1 (en) 1991-10-31
IT8721678A0 (en) 1987-08-19
BE1000811A4 (en) 1989-04-11
SE506025C2 (en) 1997-11-03
KR890002547A (en) 1989-04-10
FI873553A (en) 1988-02-21
ES2010727A6 (en) 1989-12-01
HU214439B (en) 1998-03-30
HUT44619A (en) 1988-03-28
PT85567B (en) 1991-02-08
GB2196634A (en) 1988-05-05
SE8703225D0 (en) 1987-08-19
NZ221440A (en) 1991-11-26
YU152587A (en) 1992-09-07
NO302176B1 (en) 1998-02-02
CH675728A5 (en) 1990-10-31
KR920008744B1 (en) 1992-10-09
NL8701950A (en) 1988-03-16
GB2196634B (en) 1991-05-15

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