CS8706136A2 - Method of hybridomas making for hiv-virus monoclonal antibody production - Google Patents

Method of hybridomas making for hiv-virus monoclonal antibody production

Info

Publication number
CS8706136A2
CS8706136A2 CS876136A CS613687A CS8706136A2 CS 8706136 A2 CS8706136 A2 CS 8706136A2 CS 876136 A CS876136 A CS 876136A CS 613687 A CS613687 A CS 613687A CS 8706136 A2 CS8706136 A2 CS 8706136A2
Authority
CS
Czechoslovakia
Prior art keywords
hiv
monoclonal antibody
antibody production
virus monoclonal
hybridomas making
Prior art date
Application number
CS876136A
Other languages
Czech (cs)
Other versions
CS275838B6 (en
Inventor
Kathleen M Shriver
Elaine K Thomas
Wesley L Cosand
Larry H Gosting
Edna S Dickinson
Janela Mcclure
George J Todaro
Robert C Nowinski
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Publication of CS8706136A2 publication Critical patent/CS8706136A2/en
Publication of CS275838B6 publication Critical patent/CS275838B6/en

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B25/00—Multi-stage pumps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1054—Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • AIDS & HIV (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Mechanical Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CS876136A 1986-08-20 1987-08-20 Method for production of hybridoms used for monoclonal antigen against hiv virus producing CS275838B6 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89827386A 1986-08-20 1986-08-20
US4502687A 1987-05-01 1987-05-01
US6799687A 1987-06-29 1987-06-29

Publications (2)

Publication Number Publication Date
CS8706136A2 true CS8706136A2 (en) 1990-08-14
CS275838B6 CS275838B6 (en) 1992-03-18

Family

ID=27366600

Family Applications (1)

Application Number Title Priority Date Filing Date
CS876136A CS275838B6 (en) 1986-08-20 1987-08-20 Method for production of hybridoms used for monoclonal antigen against hiv virus producing

Country Status (28)

Country Link
JP (1) JPS6485928A (en)
KR (1) KR920008744B1 (en)
AT (1) AT398080B (en)
AU (1) AU616156B2 (en)
BE (1) BE1000811A4 (en)
CH (1) CH675728A5 (en)
CS (1) CS275838B6 (en)
DE (1) DE3727703A1 (en)
DK (1) DK433087A (en)
ES (1) ES2010727A6 (en)
FI (1) FI873553A7 (en)
FR (1) FR2603107B1 (en)
GB (1) GB2196634B (en)
GR (1) GR871298B (en)
HU (1) HU214439B (en)
IE (1) IE60671B1 (en)
IL (1) IL83580A (en)
IT (1) IT1222518B (en)
LU (1) LU86972A1 (en)
NL (1) NL8701950A (en)
NO (2) NO300462B1 (en)
NZ (1) NZ221440A (en)
OA (1) OA08652A (en)
PL (1) PL155084B1 (en)
PT (1) PT85567B (en)
SE (1) SE506025C2 (en)
YU (1) YU152587A (en)
ZW (1) ZW15487A1 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP96A (en) * 1986-06-03 1990-08-12 The Usa Dept Of Commerce Small peptides which inhibit binding to T-4 receptors and act as immunogens.
AU625720B2 (en) * 1987-05-01 1992-07-16 Genetic Systems Corporation Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use
US5981278A (en) * 1987-05-29 1999-11-09 Tanox, Inc. Chimeric monoclonal antibodies which neutralize HIV-1 infection and their applications in therapy and prevention for AIDS
US5834599A (en) * 1987-05-29 1998-11-10 Tanox Biosystems, Inc. Immunoconjugates which neutralize HIV-1 infection
CA1339857C (en) * 1987-05-29 1998-05-05 Cecily Rou-Yun Sun Monoclonal antibodies to gp120 which neutraleze hiv-1
US6657050B1 (en) 1987-05-29 2003-12-02 Tanox, Inc. Chimeric viral-neutralizing immunoglobulins
JP2569185B2 (en) * 1988-01-26 1997-01-08 アメリカ合衆国 Synthetic antigen eliciting anti-HIV response
CA1341285C (en) * 1988-02-12 2001-08-14 Chang Yi Wang Synthetic peptides for the detection of antibodies to hiv gp120 envelope protein for diagnosis of aids and pre-aids conditions and as vaccines
IL90048A0 (en) * 1988-04-25 1989-12-15 Merck & Co Inc Recombinant gag precursor of hiv,its preparation and its use as aids vaccine
EP0339504A3 (en) * 1988-04-26 1990-09-12 The Du Pont Merck Pharmaceutical Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
US5562905A (en) * 1988-04-26 1996-10-08 E. I. Du Pont De Nemours And Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
FR2632310B1 (en) * 1988-06-06 1992-04-10 Pasteur Institut PEPTIDES HAVING PROTECTIVE PROPERTIES OF A PATHOGENIC VIRUS OF THE HIV TYPE IN SENSITIVE CELLS
KR900701836A (en) * 1988-10-03 1990-12-04 라메쉬 엘. 라탄 Peptides useful for diagnosing, preventing or treating new HIV proteins and AIDS
CA2025481A1 (en) * 1989-09-19 1991-03-20 Peter J. Kniskern Vaccine for aids and hepatitis b
SE9000333D0 (en) * 1990-01-31 1990-01-31 Britta Wahren MONOCLONAL ANTIBODY
SE468168B (en) * 1990-02-20 1992-11-16 Replico Medical Ab HIV-1, P24 PEPTIDES, DIAGNOSTIC ANTIGENS AND PROCEDURES FOR DIFFERENTIAL DIAGNOSTICS OF PRELIMINARY HIV-1 POSITIVE SERUM TESTS
JPH03271233A (en) * 1990-03-19 1991-12-03 Inst Pasteur Induction of protection against viral infection by synergy between viral envelope glycoproteins and peptides corresponding to neutralizing epitopes of the glycoproteins
CA2047042A1 (en) * 1990-07-19 1992-01-20 John Hannah Cyclic hiv principal neutralizing determinant peptides
CA2047078A1 (en) * 1990-07-19 1992-01-20 Steven S. Bondy Cyclic hiv principal neutralizing determinant peptides
JPH05310785A (en) * 1991-09-30 1993-11-22 Nitto Denko Corp Hiv-related cyclic peptide and adsorption material obtained by immobilizing the same
JP3520084B2 (en) * 1992-03-27 2004-04-19 アドバンスト イムニ ティ，インコーポレーテッド Peptide T and related peptides in the treatment of inflammation, including multiple sclerosis
CN103450345B (en) * 2005-12-09 2016-04-20 伟克特斯生物系统有限公司 VIP fragment and methods for using them
CN102138260B (en) 2008-09-02 2013-07-31 日本特殊陶业株式会社 Spark plug
KR102727239B1 (en) * 2022-09-07 2024-11-07 한국세라믹기술원 Magnesium oxide powder and method for manufacturing the same

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9328391B1 (en) * 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
PT81338B (en) * 1984-10-18 1987-11-11 Pasteur Institut ANTIGEN, IN PARTICULAR ANTIGEN OF THE INVOLVEMENT OF THE LINFOADENOPATHY VIRUS AND THE IMMUNO-DEFICIENCY SYNDROME ACQUIRED, AND VIRUS, PROCESS FOR PRODUCING VIRUS SURFACES ANTIGEN, USING THESE ANTIGENS IN THE PREPARATION OF IMMUNOGENIC COMPOSITIONS OR IN THE DIAGNOSIS OF THE PRESENCE OF ANTIBODIES AGAINST THIS VIRUS
GB8501473D0 (en) * 1985-01-21 1985-02-20 Pasteur Institut Cloned dna sequences
CA1341423C (en) * 1984-10-31 2003-03-04 Paul A. Luciw Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome
IE64785B1 (en) * 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
EP0220234B1 (en) * 1985-04-08 1994-08-03 Genetic Systems Corporation EXPRESSION AND DIAGNOSTIC USE OF gag ENCODED PEPTIDES WHICH ARE IMMUNOLOGICALLY REACTIVE WITH ANTIBODIES TO LAV
DK171119B1 (en) * 1985-04-19 1996-06-17 Hoffmann La Roche AIDS virus envelope protein, expression vector carrying the envelope protein, transformants transformed with the expression vector, method of producing the virus envelope protein, method of detecting AIDS antibodies, method of determining AIDS virus, vaccine against AIDS, antibodies against the virus envelope protein and use of it to prepare a vaccine and for testing
DE3650175T3 (en) * 1985-04-29 2007-09-06 Bio-Rad Laboratories, Inc., Hercules SYNTHETIC ANTIGENIC TO IDENTIFY AIDS.
GB8525615D0 (en) * 1985-10-17 1985-11-20 Hoffmann La Roche Polypeptides
JPS63501716A (en) * 1985-10-24 1988-07-14 サウスウエスト・ファウンデ−ション・フォア・バイオメディカル・リサ−チ Synthetic peptides and their use for diagnosis of AIDS and ARC and vaccine injections
WO1987002988A1 (en) * 1985-11-07 1987-05-21 President And Fellows Of Harvard College T-cell lymphotrophic virus protein and assay
US4772547A (en) * 1986-02-03 1988-09-20 Hoffmann-La Roche Inc. HTLV-III envelope peptides
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
US4925784A (en) * 1986-04-04 1990-05-15 Hoffmann-La Roche Inc. Expression and purification of an HTLV-III gag/env gene protein
DK169582B1 (en) * 1986-06-23 1994-12-12 Squibb Bristol Myers Co Human monoclonal antibody capable of reacting with an epitope on the LAV / HTLV-III envelope glycoprotein gp41, cell lines producing such antibody, pharmaceutical preparation containing the antibody, and method for determining the presence of LAV / HTLV-III in a biological sample. and method for separating specific antigenic determinants of LAV / HTLV-III using ant
EP0525828A3 (en) * 1986-08-01 1993-02-24 Repligen Corporation Recombinant polypeptides and their uses, including assay for aids virus
WO1988005051A1 (en) * 1986-12-30 1988-07-14 United States Of America, Represented By The Unite Synthetic peptides which induce cellular immunity of the aids virus and aids viral proteins

Also Published As

Publication number Publication date
FI873553A0 (en) 1987-08-17
GR871298B (en) 1988-01-12
IT8721678A0 (en) 1987-08-19
FR2603107A1 (en) 1988-02-26
IL83580A (en) 1992-11-15
NO873495D0 (en) 1987-08-19
AU616156B2 (en) 1991-10-24
SE506025C2 (en) 1997-11-03
IT1222518B (en) 1990-09-05
NO873495L (en) 1988-02-22
KR920008744B1 (en) 1992-10-09
ES2010727A6 (en) 1989-12-01
CS275838B6 (en) 1992-03-18
NZ221440A (en) 1991-11-26
GB8719587D0 (en) 1987-09-23
NO302176B1 (en) 1998-02-02
NL8701950A (en) 1988-03-16
DE3727703A1 (en) 1988-05-05
CH675728A5 (en) 1990-10-31
JPS6485928A (en) 1989-03-30
BE1000811A4 (en) 1989-04-11
ATA208987A (en) 1994-01-15
NO934897D0 (en) 1993-12-29
IL83580A0 (en) 1988-01-31
GB2196634B (en) 1991-05-15
PL155084B1 (en) 1991-10-31
DK433087A (en) 1988-02-21
IE872219L (en) 1988-02-20
LU86972A1 (en) 1988-03-02
NO934897L (en) 1993-12-29
FI873553L (en) 1988-02-21
GB2196634A (en) 1988-05-05
FI873553A7 (en) 1988-02-21
AU7720187A (en) 1988-05-19
SE8703225D0 (en) 1987-08-19
YU152587A (en) 1992-09-07
FR2603107B1 (en) 1992-04-24
HUT44619A (en) 1988-03-28
SE8703225L (en) 1988-02-21
PL267401A1 (en) 1988-07-21
IE60671B1 (en) 1994-08-10
KR890002547A (en) 1989-04-10
NO300462B1 (en) 1997-06-02
HU214439B (en) 1998-03-30
PT85567A (en) 1987-09-01
DK433087D0 (en) 1987-08-19
ZW15487A1 (en) 1988-09-14
PT85567B (en) 1991-02-08
OA08652A (en) 1988-11-30
AT398080B (en) 1994-09-26

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