HU214439B - Eljárás HIV-fertőzések kezelésére alkalmas monoklonális antitestek és peptidek, valamint ezeket tartalmazó gyógyászati készítmények és vakcinák előállítására - Google Patents
Eljárás HIV-fertőzések kezelésére alkalmas monoklonális antitestek és peptidek, valamint ezeket tartalmazó gyógyászati készítmények és vakcinák előállítására Download PDFInfo
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- HU214439B HU214439B HU873707A HU370787A HU214439B HU 214439 B HU214439 B HU 214439B HU 873707 A HU873707 A HU 873707A HU 370787 A HU370787 A HU 370787A HU 214439 B HU214439 B HU 214439B
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Classifications
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- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1054—Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
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- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2740/16011—Human Immunodeficiency Virus, HIV
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- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
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Landscapes
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- Mechanical Engineering (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US89827386A | 1986-08-20 | 1986-08-20 | |
US4502687A | 1987-05-01 | 1987-05-01 | |
US6799687A | 1987-06-29 | 1987-06-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
HUT44619A HUT44619A (en) | 1988-03-28 |
HU214439B true HU214439B (hu) | 1998-03-30 |
Family
ID=27366600
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU873707A HU214439B (hu) | 1986-08-20 | 1987-08-19 | Eljárás HIV-fertőzések kezelésére alkalmas monoklonális antitestek és peptidek, valamint ezeket tartalmazó gyógyászati készítmények és vakcinák előállítására |
Country Status (28)
Country | Link |
---|---|
JP (1) | JPS6485928A (el) |
KR (1) | KR920008744B1 (el) |
AT (1) | AT398080B (el) |
AU (1) | AU616156B2 (el) |
BE (1) | BE1000811A4 (el) |
CH (1) | CH675728A5 (el) |
CS (1) | CS275838B6 (el) |
DE (1) | DE3727703A1 (el) |
DK (1) | DK433087A (el) |
ES (1) | ES2010727A6 (el) |
FI (1) | FI873553A (el) |
FR (1) | FR2603107B1 (el) |
GB (1) | GB2196634B (el) |
GR (1) | GR871298B (el) |
HU (1) | HU214439B (el) |
IE (1) | IE60671B1 (el) |
IL (1) | IL83580A (el) |
IT (1) | IT1222518B (el) |
LU (1) | LU86972A1 (el) |
NL (1) | NL8701950A (el) |
NO (2) | NO300462B1 (el) |
NZ (1) | NZ221440A (el) |
OA (1) | OA08652A (el) |
PL (1) | PL155084B1 (el) |
PT (1) | PT85567B (el) |
SE (1) | SE506025C2 (el) |
YU (1) | YU152587A (el) |
ZW (1) | ZW15487A1 (el) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AP96A (en) * | 1986-06-03 | 1990-08-12 | The Usa Dept Of Commerce | Small peptides which inhibit binding to T-4 receptors and act as immunogens. |
AU625720B2 (en) * | 1987-05-01 | 1992-07-16 | Genetic Systems Corporation | Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use |
JP2520464B2 (ja) * | 1987-05-29 | 1996-07-31 | タノツクス・バイオシステムズ・インコーポレーテツド | Hiv―1を中和するモノクロ―ナル抗体 |
US6657050B1 (en) | 1987-05-29 | 2003-12-02 | Tanox, Inc. | Chimeric viral-neutralizing immunoglobulins |
US5981278A (en) * | 1987-05-29 | 1999-11-09 | Tanox, Inc. | Chimeric monoclonal antibodies which neutralize HIV-1 infection and their applications in therapy and prevention for AIDS |
US5834599A (en) * | 1987-05-29 | 1998-11-10 | Tanox Biosystems, Inc. | Immunoconjugates which neutralize HIV-1 infection |
JP2569185B2 (ja) * | 1988-01-26 | 1997-01-08 | アメリカ合衆国 | 抗hiv応答を喚起する合成抗原 |
CA1341285C (en) * | 1988-02-12 | 2001-08-14 | Chang Yi Wang | Synthetic peptides for the detection of antibodies to hiv gp120 envelope protein for diagnosis of aids and pre-aids conditions and as vaccines |
IL90048A0 (en) * | 1988-04-25 | 1989-12-15 | Merck & Co Inc | Recombinant gag precursor of hiv,its preparation and its use as aids vaccine |
EP0339504A3 (en) * | 1988-04-26 | 1990-09-12 | The Du Pont Merck Pharmaceutical Company | Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals |
US5562905A (en) * | 1988-04-26 | 1996-10-08 | E. I. Du Pont De Nemours And Company | Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals |
FR2632310B1 (fr) * | 1988-06-06 | 1992-04-10 | Pasteur Institut | Peptides ayant des proprietes protectrices d'un virus pathogene du type hiv dans des cellules sensibles |
JPH04502760A (ja) * | 1988-10-03 | 1992-05-21 | レプリゲン・コーポレーション | エイズの診断,予防および治療に有効な新規hiv蛋白質およびペプチド |
EP0421626A1 (en) * | 1989-09-19 | 1991-04-10 | Merck & Co. Inc. | Vaccine for aids and hepatitis B |
SE9000333D0 (sv) * | 1990-01-31 | 1990-01-31 | Britta Wahren | Monoklonal antikropp |
SE468168B (sv) * | 1990-02-20 | 1992-11-16 | Replico Medical Ab | Hiv-1, p24 peptider, diagnostiska antigener och foerfarande foer saerskiljande diagnostik av preliminaert hiv-1 positiva serumprov |
JPH03271233A (ja) * | 1990-03-19 | 1991-12-03 | Inst Pasteur | ウイルスエンベロープ糖タンパク質及びその糖タンパク質の中和エピトープに対応するペプチドの間の相乗作用による、ウイルス性感染に対する防御の誘発 |
CA2047078A1 (en) * | 1990-07-19 | 1992-01-20 | Steven S. Bondy | Cyclic hiv principal neutralizing determinant peptides |
CA2047042A1 (en) * | 1990-07-19 | 1992-01-20 | John Hannah | Cyclic hiv principal neutralizing determinant peptides |
JPH05310785A (ja) * | 1991-09-30 | 1993-11-22 | Nitto Denko Corp | Hiv関連環状ペプチドおよびこれを固定化した吸着体 |
ES2149203T3 (es) * | 1992-03-27 | 2000-11-01 | Advanced Immunit T Inc | Peptido t y peptidos asociados destinados para el tratamiento de las inflamaciones, particularmente la esclerosis multiple. |
DK2783697T3 (en) | 2005-12-09 | 2017-04-10 | Vectus Biosystems Ltd | VIP Fragments and uses thereof |
JP5165751B2 (ja) | 2008-09-02 | 2013-03-21 | 日本特殊陶業株式会社 | スパークプラグ |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9328391B1 (en) * | 1984-08-22 | 2016-05-03 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Cloning and expression of HIV-1 DNA |
DE3588254T2 (de) * | 1984-10-18 | 2008-06-26 | Institut Pasteur | GAG-Antigen und dessen Verwendung zum Nachweis von LAV-Infektion, sowie in immunogenen Zusammensetzungen |
GB8501473D0 (en) * | 1985-01-21 | 1985-02-20 | Pasteur Institut | Cloned dna sequences |
CA1341423C (en) * | 1984-10-31 | 2003-03-04 | Paul A. Luciw | Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome |
IE64785B1 (en) * | 1985-04-08 | 1995-09-06 | Genetic Systems Corp | Expression of immunologically reactive viral proteins |
DE3650011T2 (de) * | 1985-04-08 | 1994-11-17 | Genetic Systems Corp | EXPRESSION UND DIAGNOSE MIT gag-KODIERTEN PEPTIDEN, DIE MIT ANTIKÖRPERN GEGEN LAV IMMUNOLOGISCH REAKTIV SIND. |
DK171119B1 (da) * | 1985-04-19 | 1996-06-17 | Hoffmann La Roche | AIDS-viruskappeprotein, ekspressionsvektor bærende viruskappeproteinet, transformanter transformeret med ekspressionsvektoren, fremgangsmåde til fremstilling af viruskappeproteinet, fremgangsmåde til detektion af AIDS-antistoffer, fremgangsmåde til bestemmelse af AIDS-virus, vaccine mod AIDS, antistoffer mod viruskappeproteinet samt anvendelse af dette til fremstilling af en vaccine og til testnin |
WO1986006414A1 (en) * | 1985-04-29 | 1986-11-06 | Genetic Systems Corporation | Synthetic antigens for the detection of aids-related disease |
GB8525615D0 (en) * | 1985-10-17 | 1985-11-20 | Hoffmann La Roche | Polypeptides |
WO1987002775A1 (en) * | 1985-10-24 | 1987-05-07 | Southwest Foundation For Biomedical Research | Synthetic peptides and use for diagnosis and vaccination for aids and arc |
EP0245459B1 (en) * | 1985-11-07 | 1993-09-29 | The President And Fellows Of Harvard College | T-cell lymphotrophic virus protein and assay |
US4772547A (en) * | 1986-02-03 | 1988-09-20 | Hoffmann-La Roche Inc. | HTLV-III envelope peptides |
US4734362A (en) * | 1986-02-03 | 1988-03-29 | Cambridge Bioscience Corporation | Process for purifying recombinant proteins, and products thereof |
US4925784A (en) * | 1986-04-04 | 1990-05-15 | Hoffmann-La Roche Inc. | Expression and purification of an HTLV-III gag/env gene protein |
DK169582B1 (da) * | 1986-06-23 | 1994-12-12 | Squibb Bristol Myers Co | Humant monoklonalt antistof, der er i stand til at reagere med en epitop på LAV/HTLV-III kappeglycoproteinet gp41, cellelinier, som producerer sådant antistof, farmaceutisk præparat indeholdende antistoffet samt fremgangsmåde til bestemmelse af nærværelsen af LAV/HTLV-III i en biologisk prøve og fremgangsmåde til separering af specifikke antigendeterminanter af LAV/HTLV-III under anvendelse af ant |
EP0525828A3 (en) * | 1986-08-01 | 1993-02-24 | Repligen Corporation | Recombinant polypeptides and their uses, including assay for aids virus |
JPH0762031B2 (ja) * | 1986-12-30 | 1995-07-05 | アメリカ合衆国 | エイズウイルスおよびエイズウイルスのタンパク質に対する細胞性免疫を誘導する合成ペプチド |
-
1987
- 1987-08-13 NZ NZ221440A patent/NZ221440A/xx unknown
- 1987-08-14 ZW ZW154/87A patent/ZW15487A1/xx unknown
- 1987-08-17 YU YU152587A patent/YU152587A/sh unknown
- 1987-08-17 FI FI873553A patent/FI873553A/fi not_active Application Discontinuation
- 1987-08-18 ES ES8702431A patent/ES2010727A6/es not_active Expired
- 1987-08-18 IL IL83580A patent/IL83580A/xx unknown
- 1987-08-19 IE IE221987A patent/IE60671B1/en not_active IP Right Cessation
- 1987-08-19 IT IT21678/87A patent/IT1222518B/it active
- 1987-08-19 GR GR871298A patent/GR871298B/el unknown
- 1987-08-19 SE SE8703225A patent/SE506025C2/sv not_active IP Right Cessation
- 1987-08-19 FR FR878711736A patent/FR2603107B1/fr not_active Expired - Fee Related
- 1987-08-19 DK DK433087A patent/DK433087A/da not_active Application Discontinuation
- 1987-08-19 NL NL8701950A patent/NL8701950A/nl not_active Application Discontinuation
- 1987-08-19 AU AU77201/87A patent/AU616156B2/en not_active Ceased
- 1987-08-19 DE DE19873727703 patent/DE3727703A1/de not_active Withdrawn
- 1987-08-19 HU HU873707A patent/HU214439B/hu not_active IP Right Cessation
- 1987-08-19 LU LU86972A patent/LU86972A1/fr unknown
- 1987-08-19 GB GB8719587A patent/GB2196634B/en not_active Expired - Fee Related
- 1987-08-19 NO NO873495A patent/NO300462B1/no unknown
- 1987-08-19 BE BE8700922A patent/BE1000811A4/fr not_active IP Right Cessation
- 1987-08-19 KR KR1019870009058A patent/KR920008744B1/ko not_active IP Right Cessation
- 1987-08-20 JP JP62207336A patent/JPS6485928A/ja active Pending
- 1987-08-20 CS CS876136A patent/CS275838B6/cs unknown
- 1987-08-20 PL PL1987267401A patent/PL155084B1/pl unknown
- 1987-08-20 AT AT0208987A patent/AT398080B/de not_active IP Right Cessation
- 1987-08-20 CH CH3210/87A patent/CH675728A5/de not_active IP Right Cessation
- 1987-08-20 PT PT85567A patent/PT85567B/pt not_active IP Right Cessation
- 1987-08-28 OA OA59183A patent/OA08652A/xx unknown
-
1993
- 1993-12-29 NO NO934897A patent/NO302176B1/no unknown
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Legal Events
Date | Code | Title | Description |
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HMM4 | Cancellation of final prot. due to non-payment of fee |