NO302176B1 - Fremgangsmåte for fremstilling av et monoklonalt antistoff og et antigen - Google Patents

Fremgangsmåte for fremstilling av et monoklonalt antistoff og et antigen

Info

Publication number
NO302176B1
NO302176B1 NO934897A NO934897A NO302176B1 NO 302176 B1 NO302176 B1 NO 302176B1 NO 934897 A NO934897 A NO 934897A NO 934897 A NO934897 A NO 934897A NO 302176 B1 NO302176 B1 NO 302176B1
Authority
NO
Norway
Prior art keywords
antigen
preparation
monoclonal antibody
monoclonal
antibody
Prior art date
Application number
NO934897A
Other languages
English (en)
Other versions
NO934897D0 (no
NO934897L (no
Inventor
Mary Kathleen Shriver
Elaine K Thomas
Wesley L Cosand
Larry H Gosting
Edna S Dickinson
Janela Mcclure
George J Todaro
Robert C Nowinski
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Publication of NO934897D0 publication Critical patent/NO934897D0/no
Publication of NO934897L publication Critical patent/NO934897L/no
Publication of NO302176B1 publication Critical patent/NO302176B1/no

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B25/00—Multi-stage pumps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1054—Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • AIDS & HIV (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mechanical Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO934897A 1986-08-20 1993-12-29 Fremgangsmåte for fremstilling av et monoklonalt antistoff og et antigen NO302176B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89827386A 1986-08-20 1986-08-20
US4502687A 1987-05-01 1987-05-01
US6799687A 1987-06-29 1987-06-29

Publications (3)

Publication Number Publication Date
NO934897D0 NO934897D0 (no) 1993-12-29
NO934897L NO934897L (no) 1993-12-29
NO302176B1 true NO302176B1 (no) 1998-02-02

Family

ID=27366600

Family Applications (2)

Application Number Title Priority Date Filing Date
NO873495A NO300462B1 (no) 1986-08-20 1987-08-19 Monoklonale antistoffer og peptider som kan anvendes til diagnose av HIV-infeksjoner
NO934897A NO302176B1 (no) 1986-08-20 1993-12-29 Fremgangsmåte for fremstilling av et monoklonalt antistoff og et antigen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO873495A NO300462B1 (no) 1986-08-20 1987-08-19 Monoklonale antistoffer og peptider som kan anvendes til diagnose av HIV-infeksjoner

Country Status (28)

Country Link
JP (1) JPS6485928A (no)
KR (1) KR920008744B1 (no)
AT (1) AT398080B (no)
AU (1) AU616156B2 (no)
BE (1) BE1000811A4 (no)
CH (1) CH675728A5 (no)
CS (1) CS275838B6 (no)
DE (1) DE3727703A1 (no)
DK (1) DK433087A (no)
ES (1) ES2010727A6 (no)
FI (1) FI873553A (no)
FR (1) FR2603107B1 (no)
GB (1) GB2196634B (no)
GR (1) GR871298B (no)
HU (1) HU214439B (no)
IE (1) IE60671B1 (no)
IL (1) IL83580A (no)
IT (1) IT1222518B (no)
LU (1) LU86972A1 (no)
NL (1) NL8701950A (no)
NO (2) NO300462B1 (no)
NZ (1) NZ221440A (no)
OA (1) OA08652A (no)
PL (1) PL155084B1 (no)
PT (1) PT85567B (no)
SE (1) SE506025C2 (no)
YU (1) YU152587A (no)
ZW (1) ZW15487A1 (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP96A (en) * 1986-06-03 1990-08-12 The Usa Dept Of Commerce Small peptides which inhibit binding to T-4 receptors and act as immunogens.
AU625720B2 (en) * 1987-05-01 1992-07-16 Genetic Systems Corporation Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use
US5981278A (en) * 1987-05-29 1999-11-09 Tanox, Inc. Chimeric monoclonal antibodies which neutralize HIV-1 infection and their applications in therapy and prevention for AIDS
DE3853779T2 (de) * 1987-05-29 1995-09-07 Tanox Biosystems Inc Hiv-1 neutralisierende monoklonale antikörper.
US5834599A (en) * 1987-05-29 1998-11-10 Tanox Biosystems, Inc. Immunoconjugates which neutralize HIV-1 infection
US6657050B1 (en) 1987-05-29 2003-12-02 Tanox, Inc. Chimeric viral-neutralizing immunoglobulins
AU621097B2 (en) * 1988-01-26 1992-03-05 United States of America, as represented by the Secretary, U.S. Department of Commerce, The A synthetic antigen evoking anti-hiv response
CA1341285C (en) * 1988-02-12 2001-08-14 Chang Yi Wang Synthetic peptides for the detection of antibodies to hiv gp120 envelope protein for diagnosis of aids and pre-aids conditions and as vaccines
IL90048A0 (en) * 1988-04-25 1989-12-15 Merck & Co Inc Recombinant gag precursor of hiv,its preparation and its use as aids vaccine
EP0339504A3 (en) * 1988-04-26 1990-09-12 The Du Pont Merck Pharmaceutical Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
US5562905A (en) * 1988-04-26 1996-10-08 E. I. Du Pont De Nemours And Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
FR2632310B1 (fr) * 1988-06-06 1992-04-10 Pasteur Institut Peptides ayant des proprietes protectrices d'un virus pathogene du type hiv dans des cellules sensibles
JPH04502760A (ja) * 1988-10-03 1992-05-21 レプリゲン・コーポレーション エイズの診断，予防および治療に有効な新規ｈｉｖ蛋白質およびペプチド
EP0421626A1 (en) * 1989-09-19 1991-04-10 Merck & Co. Inc. Vaccine for aids and hepatitis B
SE9000333D0 (sv) * 1990-01-31 1990-01-31 Britta Wahren Monoklonal antikropp
SE468168B (sv) * 1990-02-20 1992-11-16 Replico Medical Ab Hiv-1, p24 peptider, diagnostiska antigener och foerfarande foer saerskiljande diagnostik av preliminaert hiv-1 positiva serumprov
JPH03271233A (ja) * 1990-03-19 1991-12-03 Inst Pasteur ウイルスエンベロープ糖タンパク質及びその糖タンパク質の中和エピトープに対応するペプチドの間の相乗作用による、ウイルス性感染に対する防御の誘発
CA2047078A1 (en) * 1990-07-19 1992-01-20 Steven S. Bondy Cyclic hiv principal neutralizing determinant peptides
CA2047042A1 (en) * 1990-07-19 1992-01-20 John Hannah Cyclic hiv principal neutralizing determinant peptides
JPH05310785A (ja) * 1991-09-30 1993-11-22 Nitto Denko Corp Ｈｉｖ関連環状ペプチドおよびこれを固定化した吸着体
DE69333537T2 (de) * 1992-03-27 2005-06-16 Advanced Immuni T, Inc. T-peptid und damit verwandte Peptide in der Behandlung von entzündungen einschlies slich der Multiplen Sklerose
US8470778B2 (en) 2005-12-09 2013-06-25 Vectus Biosystems Limited VIP fragments and methods of use
WO2010026940A1 (ja) 2008-09-02 2010-03-11 日本特殊陶業株式会社 スパークプラグ

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9328391B1 (en) * 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
GB8501473D0 (en) * 1985-01-21 1985-02-20 Pasteur Institut Cloned dna sequences
ATE250083T1 (de) * 1984-10-18 2003-10-15 Pasteur Institut Lav-antigene und -peptide
CA1341423C (en) * 1984-10-31 2003-03-04 Paul A. Luciw Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome
EP0220234B1 (en) * 1985-04-08 1994-08-03 Genetic Systems Corporation EXPRESSION AND DIAGNOSTIC USE OF gag ENCODED PEPTIDES WHICH ARE IMMUNOLOGICALLY REACTIVE WITH ANTIBODIES TO LAV
IE64785B1 (en) * 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
NZ215867A (en) * 1985-04-19 1989-10-27 Hoffmann La Roche Aids envelope protein, dna vectors and method of production
DE3650175T3 (de) * 1985-04-29 2007-09-06 Bio-Rad Laboratories, Inc., Hercules Synthetische antigene zum nachweis von aids.
GB8525615D0 (en) * 1985-10-17 1985-11-20 Hoffmann La Roche Polypeptides
DE3689941D1 (de) * 1985-10-24 1994-08-04 Southwest Found Biomed Res Synthetische peptide und deren verwendung zur diagnose und impfung für aids und arc.
JP2837669B2 (ja) * 1985-11-07 1998-12-16 プレジデント アンド フエロウズ オブ ハ−バ−ド カレツジ Ｔ−細胞リンパ趨行性ウイルス蛋白及びその分析
US4772547A (en) * 1986-02-03 1988-09-20 Hoffmann-La Roche Inc. HTLV-III envelope peptides
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
US4925784A (en) * 1986-04-04 1990-05-15 Hoffmann-La Roche Inc. Expression and purification of an HTLV-III gag/env gene protein
DK169582B1 (da) * 1986-06-23 1994-12-12 Squibb Bristol Myers Co Humant monoklonalt antistof, der er i stand til at reagere med en epitop på LAV/HTLV-III kappeglycoproteinet gp41, cellelinier, som producerer sådant antistof, farmaceutisk præparat indeholdende antistoffet samt fremgangsmåde til bestemmelse af nærværelsen af LAV/HTLV-III i en biologisk prøve og fremgangsmåde til separering af specifikke antigendeterminanter af LAV/HTLV-III under anvendelse af ant
EP0255190A3 (en) * 1986-08-01 1990-08-29 Repligen Corporation Recombinant polypeptides and their uses, inclusing assay for aids virus
JPH0762031B2 (ja) * 1986-12-30 1995-07-05 アメリカ合衆国 エイズウイルスおよびエイズウイルスのタンパク質に対する細胞性免疫を誘導する合成ペプチド

Also Published As

Publication number Publication date
PL155084B1 (en) 1991-10-31
PT85567A (en) 1987-09-01
CS8706136A2 (en) 1990-08-14
SE8703225D0 (sv) 1987-08-19
NO934897D0 (no) 1993-12-29
PL267401A1 (en) 1988-07-21
FI873553A0 (fi) 1987-08-17
GB2196634B (en) 1991-05-15
DK433087D0 (da) 1987-08-19
CS275838B6 (en) 1992-03-18
NO300462B1 (no) 1997-06-02
SE506025C2 (sv) 1997-11-03
IT1222518B (it) 1990-09-05
ATA208987A (de) 1994-01-15
BE1000811A4 (fr) 1989-04-11
SE8703225L (sv) 1988-02-21
NO934897L (no) 1993-12-29
DK433087A (da) 1988-02-21
GB8719587D0 (en) 1987-09-23
GB2196634A (en) 1988-05-05
DE3727703A1 (de) 1988-05-05
YU152587A (sh) 1992-09-07
FR2603107A1 (fr) 1988-02-26
FR2603107B1 (fr) 1992-04-24
NZ221440A (en) 1991-11-26
KR890002547A (ko) 1989-04-10
OA08652A (fr) 1988-11-30
AT398080B (de) 1994-09-26
IT8721678A0 (it) 1987-08-19
CH675728A5 (no) 1990-10-31
IE872219L (en) 1988-02-20
NO873495L (no) 1988-02-22
ZW15487A1 (en) 1988-09-14
IL83580A0 (en) 1988-01-31
HUT44619A (en) 1988-03-28
FI873553A (fi) 1988-02-21
IE60671B1 (en) 1994-08-10
IL83580A (en) 1992-11-15
AU616156B2 (en) 1991-10-24
AU7720187A (en) 1988-05-19
NL8701950A (nl) 1988-03-16
JPS6485928A (en) 1989-03-30
GR871298B (en) 1988-01-12
KR920008744B1 (ko) 1992-10-09
LU86972A1 (fr) 1988-03-02
ES2010727A6 (es) 1989-12-01
PT85567B (pt) 1991-02-08
HU214439B (hu) 1998-03-30
NO873495D0 (no) 1987-08-19

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