JPS6411910B2 - - Google Patents
Info
- Publication number
- JPS6411910B2 JPS6411910B2 JP18755480A JP18755480A JPS6411910B2 JP S6411910 B2 JPS6411910 B2 JP S6411910B2 JP 18755480 A JP18755480 A JP 18755480A JP 18755480 A JP18755480 A JP 18755480A JP S6411910 B2 JPS6411910 B2 JP S6411910B2
- Authority
- JP
- Japan
- Prior art keywords
- dispensing
- sample
- reaction
- blood
- serum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000000601 blood cell Anatomy 0.000 claims description 89
- 239000002245 particle Substances 0.000 claims description 41
- 238000000034 method Methods 0.000 claims description 35
- 239000003085 diluting agent Substances 0.000 claims description 28
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 5
- 229910052799 carbon Inorganic materials 0.000 claims description 5
- 238000007865 diluting Methods 0.000 claims description 5
- 239000004816 latex Substances 0.000 claims description 5
- 229920000126 latex Polymers 0.000 claims description 5
- 239000011521 glass Substances 0.000 claims description 2
- 238000006243 chemical reaction Methods 0.000 description 101
- 239000000523 sample Substances 0.000 description 90
- 210000002966 serum Anatomy 0.000 description 57
- 239000003153 chemical reaction reagent Substances 0.000 description 51
- 210000004369 blood Anatomy 0.000 description 38
- 239000008280 blood Substances 0.000 description 38
- 238000004140 cleaning Methods 0.000 description 30
- 239000007788 liquid Substances 0.000 description 24
- 238000012360 testing method Methods 0.000 description 20
- 239000012895 dilution Substances 0.000 description 18
- 238000010790 dilution Methods 0.000 description 18
- 238000004458 analytical method Methods 0.000 description 17
- 239000006285 cell suspension Substances 0.000 description 16
- 238000012546 transfer Methods 0.000 description 16
- 230000004520 agglutination Effects 0.000 description 11
- 230000002776 aggregation Effects 0.000 description 9
- 238000004220 aggregation Methods 0.000 description 9
- 238000001514 detection method Methods 0.000 description 9
- 238000007599 discharging Methods 0.000 description 8
- 230000001900 immune effect Effects 0.000 description 8
- 239000000427 antigen Substances 0.000 description 7
- 102000036639 antigens Human genes 0.000 description 7
- 108091007433 antigens Proteins 0.000 description 7
- 239000012085 test solution Substances 0.000 description 7
- 108010004032 Bromelains Proteins 0.000 description 6
- 238000009739 binding Methods 0.000 description 6
- 238000003756 stirring Methods 0.000 description 6
- 239000008363 phosphate buffer Substances 0.000 description 5
- 239000002504 physiological saline solution Substances 0.000 description 5
- 238000004062 sedimentation Methods 0.000 description 5
- 210000003743 erythrocyte Anatomy 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 238000003860 storage Methods 0.000 description 4
- 241000700605 Viruses Species 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 238000007796 conventional method Methods 0.000 description 3
- 239000011159 matrix material Substances 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 239000012898 sample dilution Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 208000006379 syphilis Diseases 0.000 description 3
- 238000009825 accumulation Methods 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000012470 diluted sample Substances 0.000 description 2
- 238000005286 illumination Methods 0.000 description 2
- 230000001788 irregular Effects 0.000 description 2
- 210000000265 leukocyte Anatomy 0.000 description 2
- 210000004698 lymphocyte Anatomy 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 241001494479 Pecora Species 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 208000030452 Transient pseudohypoaldosteronism Diseases 0.000 description 1
- 235000019835 bromelain Nutrition 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- -1 etc. Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP18755480A JPS57111451A (en) | 1980-12-29 | 1980-12-29 | Dispensing method for particle sample |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP18755480A JPS57111451A (en) | 1980-12-29 | 1980-12-29 | Dispensing method for particle sample |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS57111451A JPS57111451A (en) | 1982-07-10 |
| JPS6411910B2 true JPS6411910B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1989-02-27 |
Family
ID=16208104
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP18755480A Granted JPS57111451A (en) | 1980-12-29 | 1980-12-29 | Dispensing method for particle sample |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57111451A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993007494A1 (en) * | 1991-10-04 | 1993-04-15 | Aloka Kabushiki Kaisha | Method of pipetting of blood sample |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57208461A (en) * | 1981-06-18 | 1982-12-21 | Shimadzu Corp | Distributing method for liquid sample |
| JPS58102155A (ja) * | 1981-12-14 | 1983-06-17 | Olympus Optical Co Ltd | 血球浮遊液作成方法 |
| JPS60149945A (ja) * | 1984-01-18 | 1985-08-07 | Tokyo Electric Power Co Inc:The | 希釈方法及び装置 |
| US4738825A (en) * | 1985-02-27 | 1988-04-19 | Fisher Scientific Company | Cuvette handling |
| US4676951A (en) * | 1985-07-01 | 1987-06-30 | American Hospital Supply Corp. | Automatic specimen analyzing system |
| GR871619B (en) * | 1986-10-31 | 1988-03-03 | Genetic Systems Corp | Automated patient sample analysis instrument |
| JP2656567B2 (ja) * | 1988-08-31 | 1997-09-24 | 株式会社日立製作所 | 自動分析システム |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5153039U (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1974-10-21 | 1976-04-22 | ||
| US4141469A (en) * | 1977-05-02 | 1979-02-27 | Lee Thomas E | Microdispensing dilution system |
-
1980
- 1980-12-29 JP JP18755480A patent/JPS57111451A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993007494A1 (en) * | 1991-10-04 | 1993-04-15 | Aloka Kabushiki Kaisha | Method of pipetting of blood sample |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS57111451A (en) | 1982-07-10 |