JPS6343711B2 - - Google Patents

Info

Publication number
JPS6343711B2
JPS6343711B2 JP54170179A JP17017979A JPS6343711B2 JP S6343711 B2 JPS6343711 B2 JP S6343711B2 JP 54170179 A JP54170179 A JP 54170179A JP 17017979 A JP17017979 A JP 17017979A JP S6343711 B2 JPS6343711 B2 JP S6343711B2
Authority
JP
Japan
Prior art keywords
lectin
sugar
product
insolubilized
antigens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP54170179A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5593063A (en
Inventor
Ii Chuu Arubaato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
E-Y Laboratories Inc
Original Assignee
E-Y Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E-Y Laboratories Inc filed Critical E-Y Laboratories Inc
Publication of JPS5593063A publication Critical patent/JPS5593063A/ja
Publication of JPS6343711B2 publication Critical patent/JPS6343711B2/ja
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/5375—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by changing the physical or chemical properties of the medium or immunochemicals, e.g. temperature, density, pH, partitioning
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/04—Sandwich assay format

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP17017979A 1978-12-26 1979-12-26 Immunological measurement using lectin Granted JPS5593063A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/972,696 US4289747A (en) 1978-12-26 1978-12-26 Immunological determination using lectin

Publications (2)

Publication Number Publication Date
JPS5593063A JPS5593063A (en) 1980-07-15
JPS6343711B2 true JPS6343711B2 (enExample) 1988-09-01

Family

ID=25520012

Family Applications (1)

Application Number Title Priority Date Filing Date
JP17017979A Granted JPS5593063A (en) 1978-12-26 1979-12-26 Immunological measurement using lectin

Country Status (3)

Country Link
US (1) US4289747A (enExample)
JP (1) JPS5593063A (enExample)
DE (1) DE2951678A1 (enExample)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4493793A (en) * 1978-12-26 1985-01-15 E-Y Laboratories Soluble immunoassay reagent comprising lectin covalently bonded to reactive component
US4371515A (en) * 1978-12-26 1983-02-01 E-Y Laboratories, Inc. Method for forming an isolated lectin-immunological conjugate
SE451508B (sv) * 1979-01-30 1987-10-12 Otsuka Pharma Co Ltd Bestemning av substanser med tumorassocierade glykobindningar medelst lektiner som specifikt binder till terminala galaktos (beta 1 - 3 eller beta 1 - 4)-n-acetylglukosamin- eller -n-acetylgalaktosamingrupper samt cance
DE3003836A1 (de) * 1980-02-02 1981-08-13 Merck Patent Gmbh, 6100 Darmstadt Verfahren und mittel zur bestimmung einer komponente aus einer gruppe bestehend aus spezifisch bindenden rezeptoren und substanzen, die von diesen rezeptoren spezifisch gebunden werden koennen
EP0041426B1 (fr) * 1980-05-22 1985-11-13 Institut Pasteur Produit de couplage entre une lectine et un ligand spécifique, obtention et application dans le domaine biologique
SE447028B (sv) * 1980-06-30 1986-10-20 Erik Audunn Cerven Bestemning av endstaende sackaridgrupper i glykoprotein
JPS5729949A (en) * 1980-07-30 1982-02-18 Nippon Koutai Kenkyusho:Kk Determination of sugar branch related to cancer and diagnostic technique of cancer
US4450104A (en) * 1980-09-30 1984-05-22 Cutter Laboratories, Inc. Water insoluble gel matrix containing lectin bound to antithrombin
US4446314A (en) * 1980-09-30 1984-05-01 Cutter Laboratories, Inc. Fractionation of heparin
US4330299A (en) * 1981-03-09 1982-05-18 Evreka, Inc. Article and method for measuring glucose level in body fluids
US4425438A (en) * 1981-03-13 1984-01-10 Bauman David S Assay method and device
IL63855A (en) * 1981-09-16 1984-10-31 Teva Pharma Method and kit for detecting pregnancy
FR2520877B1 (fr) * 1982-01-29 1987-07-03 Otsuka Pharma Co Ltd Procede pour la determination des composes a liaisons gluco associes aux tumeurs
US4455380A (en) * 1982-01-29 1984-06-19 Otsuka Pharmaceutical Co., Ltd. Process for determining tumor-associated glycolinkage
US4504585A (en) * 1982-04-05 1985-03-12 Aalto Scientific, Ltd. Affinity immunoassay system
US4530900A (en) * 1982-09-13 1985-07-23 Seragen Diagnostics Inc. Soluble insoluble polymers in enzymeimmunoassay
EP0126772A1 (en) * 1982-12-03 1984-12-05 E.I. Du Pont De Nemours And Company Chromogenic support immunoassay
US4687732A (en) * 1983-06-10 1987-08-18 Yale University Visualization polymers and their application to diagnostic medicine
US4500788A (en) * 1983-08-19 1985-02-19 Baxter Travenol Laboratories, Inc. Device for providing antibacterial radiation
WO1985001442A1 (en) * 1983-09-28 1985-04-11 Summa Medical Corporation Lectin composition and method for diagnosis of cancer
FI852545A7 (fi) * 1984-06-29 1985-12-30 Ortho Diagnostic Systems Inc Vasta-aine-lektiini kerrosanalyysi.
US4737453A (en) * 1984-12-12 1988-04-12 Immunomedics, Inc. Sandwich immunoassay utilizing a separation specific binding substance
DE3679690D1 (de) * 1985-03-19 1991-07-18 Abbott Lab Diagnostische probe, die mikroperoxidase verwendet.
US4935339A (en) * 1985-05-07 1990-06-19 Nichols Institute Diagnostics Delayed solid phase immunologic assay
US4803170A (en) * 1985-05-09 1989-02-07 Ultra Diagnostics Corporation Competitive immunoassay method, device and test kit
US4746631A (en) * 1985-05-09 1988-05-24 Ultra Diagnostics Corporation Immunoassay method, device, and test kit
US4806311A (en) * 1985-08-28 1989-02-21 Miles Inc. Multizone analytical element having labeled reagent concentration zone
US4933275A (en) * 1985-10-24 1990-06-12 The General Hospital Corporation Method for the detection of a polypeptide subunit in the presence of a quaternary protein containing the subunit
US5239062A (en) * 1986-03-20 1993-08-24 Dana-Farber Cancer Institute, Inc. Blocked lectins, methods and affinity support for making same using affinity ligands, and method of killing selected cell populations having reduced nonselective cytotoxicity
WO1987005515A1 (en) * 1986-03-20 1987-09-24 Dana-Farber Cancer Institute, Inc. Lectin complex and method and probe for making same
US5395924A (en) * 1986-03-20 1995-03-07 Dana-Farber Cancer Institute, Inc. Blocked lectins; methods and affinity support for making the same using affinity ligands; and method of killing selected cell populations having reduced non-selective cytotoxicity
US5494800A (en) * 1987-01-29 1996-02-27 Cytosignet, Inc. Analyte detection in particulate-containing samples
IT1230673B (it) * 1987-09-04 1991-10-29 Sclavo Spa Metodo per la immunolocalizzazione di antigeni con l'impiego di anticorpi diretti contro epitopi di natura non glucidica
EP0353895A1 (en) * 1988-07-18 1990-02-07 MITSUI TOATSU CHEMICALS, Inc. Immunoassay method
DE3829245A1 (de) * 1988-08-29 1990-03-01 Boehringer Mannheim Gmbh Verfahren zur bestimmung einer spezifisch bindefaehigen substanz
DE3900639A1 (de) * 1988-12-23 1990-06-28 Boehringer Mannheim Gmbh Verfahren zum nachweis von kohlenhydrathaltigen verbindungen und dazu geeignetes reagenz
ATE131933T1 (de) * 1990-01-09 1996-01-15 Wako Pure Chem Ind Ltd Verfahren zur abtrennung und messung von spurbestandteilen
US5277892A (en) * 1990-08-08 1994-01-11 Rhomed Incorporated In vivo lymphocyte tagging
IE920778A1 (en) * 1991-03-12 1992-09-23 Du Pont Method for specific binding assays using a releasable ligand
US5643549A (en) * 1992-02-20 1997-07-01 Rhomed Incorporated Leukostimulatory agent for in vivo leukocyte tagging
JP3451783B2 (ja) * 1995-04-18 2003-09-29 東ソー株式会社 コリンエステラーゼの測定法及び肝硬変と肝炎の識別法
SE9602545L (sv) * 1996-06-25 1997-12-26 Michael Mecklenburg Metod för att diskriminera komplexa biologiska prover
US6770453B1 (en) 2000-03-06 2004-08-03 The Regents Of The University Of California Methods of detecting chitinous material in a non-chitinous biological material
US6833250B2 (en) 2000-03-06 2004-12-21 Vicam, L.P. Detection and removal of chitinous material in a biological sample
US9249229B2 (en) * 2000-12-08 2016-02-02 Alexion Pharmaceuticals, Inc. Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
US7408041B2 (en) * 2000-12-08 2008-08-05 Alexion Pharmaceuticals, Inc. Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
US20040198661A1 (en) * 2000-12-08 2004-10-07 Bowdish Katherine S. Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
JP4280803B2 (ja) * 2000-12-08 2009-06-17 アレクシオン ファーマシューティカルズ， インコーポレイテッド 慢性リンパ性白血病細胞株および抗体を産生するためのその使用
US20060057651A1 (en) * 2000-12-08 2006-03-16 Bowdish Katherine S Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
CA2447695C (en) 2001-06-01 2015-02-24 Cornell Research Foundation, Inc. Modified antibodies to prostate-specific membrane antigen and uses thereof
US20050089515A1 (en) 2003-08-29 2005-04-28 Dyax Corp. Poly-pegylated protease inhibitors
WO2005115394A2 (en) * 2004-04-20 2005-12-08 New York University School Of Medicine Prenyl-electrostatic switch, and methods of use
US7973134B2 (en) * 2004-07-07 2011-07-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in anaplastic large cell lymphoma signaling pathways
US7527979B2 (en) * 2004-08-18 2009-05-05 Florida State University Research Foundation Devices and methods for rapid detection of pathogens
US7527980B2 (en) * 2004-08-18 2009-05-05 Florida State University Research Foundation Indirect detection of cardiac markers for assessing acute myocardial infarction
US7935790B2 (en) * 2004-10-04 2011-05-03 Cell Singaling Technology, Inc. Reagents for the detection of protein phosphorylation in T-cell receptor signaling pathways
US7807789B2 (en) * 2004-12-21 2010-10-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in EGFR-signaling pathways
EP3058955B1 (en) 2005-03-24 2019-05-29 Millennium Pharmaceuticals, Inc. Antibodies that bind ov064 and methods of use therefor
US20090099340A1 (en) * 2007-10-12 2009-04-16 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
WO2007027906A2 (en) * 2005-08-31 2007-03-08 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in leukemia signaling pathways
US20100151495A9 (en) * 2005-08-31 2010-06-17 Cell Signaling Technolgy, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
EP2463305B1 (en) * 2006-01-12 2016-05-11 Alexion Pharmaceuticals, Inc. Antibodies to OX-2/CD200 and uses thereof
WO2007127335A2 (en) * 2006-04-27 2007-11-08 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in atm and atr kinase signaling pathways
US7939636B2 (en) * 2006-08-11 2011-05-10 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in c-Src signaling pathways
US20090258442A1 (en) * 2006-08-31 2009-10-15 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
US20090081659A1 (en) 2007-03-07 2009-03-26 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
US20090068684A1 (en) * 2007-03-26 2009-03-12 Cell Signaling Technology, Inc. Serine and threoninephosphorylation sites
US20080238709A1 (en) * 2007-03-28 2008-10-02 Faramarz Vaziri One-way communication apparatus with dynamic key generation
AU2008234530B2 (en) 2007-03-29 2013-03-28 Technion Research & Development Foundation Ltd. Antibodies, methods and kits for diagnosing and treating melanoma
EP1983003A3 (en) 2007-04-19 2009-03-11 Peter Hornbeck Tyrosine phosphorylation sites and antibodies specific for them
US7977462B2 (en) 2007-04-19 2011-07-12 Cell Signaling Technology, Inc. Tyrosine phosphorylation sites
EP1983002A3 (en) 2007-04-19 2009-03-11 Peter Hornbeck Tyrosine phosphorylation sites and antibodies specific for them
US20090053831A1 (en) 2007-05-01 2009-02-26 Cell Signaling Technology, Inc. Tyrosine phosphorylation sites
AU2008279618B2 (en) * 2007-07-25 2014-05-22 Alexion Pharmaceuticals, Inc. Methods and compositions for treating autoimmune disease
EP2062920A3 (en) 2007-11-21 2009-06-17 Peter Hornbeck Protein phosphorylation by basophilic serine/threonine kinases in insulin signalling pathways
WO2015164330A1 (en) 2014-04-21 2015-10-29 Millennium Pharmaceuticals, Inc. Anti-psyk antibody molecules and use of same for syk-targeted therapy
US20090220991A1 (en) * 2008-02-29 2009-09-03 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in leukemia signaling pathways
EP2274437B1 (en) 2008-04-10 2015-12-23 Cell Signaling Technology, Inc. Compositions and methods for detecting egfr mutations in cancer
BRPI0910622A2 (pt) 2008-04-25 2020-03-10 Dyax Corp. ANTICORPOS CONTRA FcRn E USOS DOS MESMOS
WO2009148896A2 (en) 2008-05-29 2009-12-10 Nuclea Biotechnologies, LLC Anti-phospho-akt antibodies
JP2012505900A (ja) 2008-10-14 2012-03-08 ダイアクス コーポレーション 全身性強皮症に伴う肺線維症の治療および予防のためのｉｇｆ−ｉｉ／ｉｇｆ−ｉｉｅ結合タンパク質の使用
WO2011004379A1 (en) 2009-07-10 2011-01-13 Tel Hashomer Medical Research Infrastructure And Services Ltd. Compositions and methods for treating cancer
PH12012500665B1 (en) 2009-10-23 2019-10-30 Amgen British Columbia Anti-gcc antibody molecules and related compositions and methods
HRP20220107T1 (hr) 2010-01-06 2022-04-15 Takeda Pharmaceutical Company Limited Proteini koji vežu kalikrein plazme
WO2011092700A1 (en) 2010-01-27 2011-08-04 Yeda Research And Development Co. Ltd. Antibodies that inhibit metalloproteins
WO2012007950A2 (en) 2010-07-15 2012-01-19 Technion Research & Development Foundation Ltd. Isolated high affinity entities with t-cell receptor like specificity towards native complexes of mhc class ii and diabetes-associated autoantigenic peptides
BR112013000985A2 (pt) 2010-07-15 2017-09-05 Technion Res & Dev Foundation Entidades isoladas de alta afinidade com especificidade semelhante à do receptor de célula t em relação a complexos nativos de mhc classe ii e peptídeos autoantigênicos de descarboxilase do ácido glutâmico (gad)
US20130210663A1 (en) 2010-08-04 2013-08-15 Cizzle Biotechnology Limited Methods and compounds for the diagnosis and treatment of cancer
CN103370337B (zh) 2010-10-28 2015-12-09 耶达研究及发展有限公司 用于产生针对金属酶的抗体的方法
EP2714084B1 (en) 2011-06-02 2019-05-22 Dyax Corp. Fc RECEPTOR BINDING PROTEINS
US9156915B2 (en) 2012-04-26 2015-10-13 Thomas Jefferson University Anti-GCC antibody molecules
US11105809B2 (en) 2012-10-09 2021-08-31 Ramot At Tel-Aviv University Ltd. Methods and kits for predicting prognosis of cancer using soluble mortalin in blood
KR20170041192A (ko) 2014-06-25 2017-04-14 텔 하쇼머 메디컬 리서치 인프라스트럭쳐 앤드 서비시스 리미티드． 암 줄기세포 마커의 동정 및 진단 및 치료를 위한 그의 사용
EP3294280A1 (en) 2015-05-11 2018-03-21 Yeda Research and Development Co., Ltd. Citrin inhibitors for the treatment of cancer
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
JP2019503985A (ja) 2015-11-03 2019-02-14 グリコミメティクス， インコーポレイテッド モノクローナル抗体、造血幹細胞の産生のための方法および組成物、ならびにそれらを使用する方法
AU2016349787A1 (en) 2015-11-03 2018-05-17 Glycomimetics, Inc. Antibodies for targeting cancer stem cells and treating aggressive cancers
JP2020501506A (ja) 2016-09-07 2020-01-23 イッサム リサーチ デベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム エルティーディー． 抗ＮＫｐ４６抗体およびその治療的使用
WO2019067499A1 (en) 2017-09-27 2019-04-04 Alexion Pharmaceuticals, Inc. BIOMARKER SIGNATURE FOR PREDICTING A TUMOR RESPONSE TO ANTI-CD200 THERAPY
IL264768A (en) 2019-02-10 2020-08-31 Sagi Irit ANTI-MATRIX METALLOPROTEINASE 7 (MMP-7) inhibitory antibody and its use
US20220251193A1 (en) 2019-06-27 2022-08-11 Ramot At Tel-Aviv University Ltd. Semaphorin 3a antibodies and uses thereof
AU2020384953A1 (en) 2019-11-11 2022-06-23 Ibi-Ag Innovative Bio Insecticides Ltd. Insect control nanobodies and uses thereof
EP4584297A1 (en) 2022-09-11 2025-07-16 Yeda Research and Development Co. Ltd Anti-klk4 antibodies and uses thereof
WO2025154058A1 (en) 2024-01-21 2025-07-24 Ibi-Ag Innovative Bio Insecticides Ltd. Anti-insect hsp70 nanobodies and uses thereof
WO2025154056A1 (en) 2024-01-21 2025-07-24 Ibi-Ag Innovative Bio Insecticides Ltd. Anti-insect cda nanobodies and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE343949B (enExample) * 1966-06-02 1972-03-20 Pharmacia Ab
US4053284A (en) * 1976-03-10 1977-10-11 Akzona Incorporated Continuous flow apparatus for biological testing
US4098876A (en) * 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay

Also Published As

Publication number Publication date
US4289747A (en) 1981-09-15
JPS5593063A (en) 1980-07-15
DE2951678A1 (de) 1980-07-10

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