DE2951678A1 - Immunologische bestimmung mit hilfe von lectin - Google Patents
Immunologische bestimmung mit hilfe von lectinInfo
- Publication number
- DE2951678A1 DE2951678A1 DE19792951678 DE2951678A DE2951678A1 DE 2951678 A1 DE2951678 A1 DE 2951678A1 DE 19792951678 DE19792951678 DE 19792951678 DE 2951678 A DE2951678 A DE 2951678A DE 2951678 A1 DE2951678 A1 DE 2951678A1
- Authority
- DE
- Germany
- Prior art keywords
- lectin
- sugar
- bound
- insolubilized
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/5375—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by changing the physical or chemical properties of the medium or immunochemicals, e.g. temperature, density, pH, partitioning
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
- G01N2470/04—Sandwich assay format
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/972,696 US4289747A (en) | 1978-12-26 | 1978-12-26 | Immunological determination using lectin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2951678A1 true DE2951678A1 (de) | 1980-07-10 |
Family
ID=25520012
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19792951678 Withdrawn DE2951678A1 (de) | 1978-12-26 | 1979-12-21 | Immunologische bestimmung mit hilfe von lectin |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US4289747A (enExample) |
| JP (1) | JPS5593063A (enExample) |
| DE (1) | DE2951678A1 (enExample) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0033437A1 (de) * | 1980-02-02 | 1981-08-12 | MERCK PATENT GmbH | Verfahren und Mittel zur Bestimmung einer Komponente aus einer Gruppe bestehend aus spezifisch bindende Rezeptoren und Substanzen, die von diesen Rezeptoren spezifisch gebunden werden können |
| EP0041426A1 (fr) * | 1980-05-22 | 1981-12-09 | Institut Pasteur | Produit de couplage entre une lectine et un ligand spécifique, obtention et application dans le domaine biologique |
| EP0043359A3 (en) * | 1980-06-30 | 1982-01-20 | Pharmacia Diagnostics Ab | Determination of terminal saccharide groups in glycoprotein |
| EP0201079A3 (en) * | 1985-05-07 | 1989-05-24 | Richard Zahradnik | Delayed solid phase immunologic assay |
| EP0353895A1 (en) * | 1988-07-18 | 1990-02-07 | MITSUI TOATSU CHEMICALS, Inc. | Immunoassay method |
| EP0441470A3 (en) * | 1990-01-09 | 1993-02-03 | Wako Pure Chemical Industries Ltd | Process for separating and measuring trace components |
| EP0628315A1 (en) * | 1986-03-20 | 1994-12-14 | Dana-Farber Cancer Institute, Inc. | Lectin complex and probe and method for making same |
Families Citing this family (98)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4493793A (en) * | 1978-12-26 | 1985-01-15 | E-Y Laboratories | Soluble immunoassay reagent comprising lectin covalently bonded to reactive component |
| US4371515A (en) * | 1978-12-26 | 1983-02-01 | E-Y Laboratories, Inc. | Method for forming an isolated lectin-immunological conjugate |
| GB2043890B (en) * | 1979-01-30 | 1983-09-07 | Otsuka Pharma Co Ltd | Determination of tumour associated glycolinkage and diagnosis of cancer |
| JPS5729949A (en) * | 1980-07-30 | 1982-02-18 | Nippon Koutai Kenkyusho:Kk | Determination of sugar branch related to cancer and diagnostic technique of cancer |
| US4446314A (en) * | 1980-09-30 | 1984-05-01 | Cutter Laboratories, Inc. | Fractionation of heparin |
| US4450104A (en) * | 1980-09-30 | 1984-05-22 | Cutter Laboratories, Inc. | Water insoluble gel matrix containing lectin bound to antithrombin |
| US4330299A (en) * | 1981-03-09 | 1982-05-18 | Evreka, Inc. | Article and method for measuring glucose level in body fluids |
| US4425438A (en) * | 1981-03-13 | 1984-01-10 | Bauman David S | Assay method and device |
| IL63855A (en) * | 1981-09-16 | 1984-10-31 | Teva Pharma | Method and kit for detecting pregnancy |
| FR2520877B1 (fr) * | 1982-01-29 | 1987-07-03 | Otsuka Pharma Co Ltd | Procede pour la determination des composes a liaisons gluco associes aux tumeurs |
| CH653442A5 (en) * | 1982-01-29 | 1985-12-31 | Otsuka Pharma Co Ltd | Process for the determination of tumour-associated glucoside derivatives |
| US4504585A (en) * | 1982-04-05 | 1985-03-12 | Aalto Scientific, Ltd. | Affinity immunoassay system |
| US4530900A (en) * | 1982-09-13 | 1985-07-23 | Seragen Diagnostics Inc. | Soluble insoluble polymers in enzymeimmunoassay |
| WO1984002193A1 (en) * | 1982-12-03 | 1984-06-07 | Du Pont | Chromogenic support immunoassay |
| US4687732A (en) * | 1983-06-10 | 1987-08-18 | Yale University | Visualization polymers and their application to diagnostic medicine |
| US4500788A (en) * | 1983-08-19 | 1985-02-19 | Baxter Travenol Laboratories, Inc. | Device for providing antibacterial radiation |
| WO1985001442A1 (en) * | 1983-09-28 | 1985-04-11 | Summa Medical Corporation | Lectin composition and method for diagnosis of cancer |
| FI852545L (fi) * | 1984-06-29 | 1985-12-30 | Ortho Diagnostic Systems Inc | Sandwichanalys av antikroppslektin. |
| US4737453A (en) * | 1984-12-12 | 1988-04-12 | Immunomedics, Inc. | Sandwich immunoassay utilizing a separation specific binding substance |
| DE3679690D1 (de) * | 1985-03-19 | 1991-07-18 | Abbott Lab | Diagnostische probe, die mikroperoxidase verwendet. |
| US4746631A (en) * | 1985-05-09 | 1988-05-24 | Ultra Diagnostics Corporation | Immunoassay method, device, and test kit |
| US4803170A (en) * | 1985-05-09 | 1989-02-07 | Ultra Diagnostics Corporation | Competitive immunoassay method, device and test kit |
| US4806311A (en) * | 1985-08-28 | 1989-02-21 | Miles Inc. | Multizone analytical element having labeled reagent concentration zone |
| US4933275A (en) * | 1985-10-24 | 1990-06-12 | The General Hospital Corporation | Method for the detection of a polypeptide subunit in the presence of a quaternary protein containing the subunit |
| US5239062A (en) * | 1986-03-20 | 1993-08-24 | Dana-Farber Cancer Institute, Inc. | Blocked lectins, methods and affinity support for making same using affinity ligands, and method of killing selected cell populations having reduced nonselective cytotoxicity |
| US5395924A (en) * | 1986-03-20 | 1995-03-07 | Dana-Farber Cancer Institute, Inc. | Blocked lectins; methods and affinity support for making the same using affinity ligands; and method of killing selected cell populations having reduced non-selective cytotoxicity |
| US5494800A (en) * | 1987-01-29 | 1996-02-27 | Cytosignet, Inc. | Analyte detection in particulate-containing samples |
| IT1230673B (it) * | 1987-09-04 | 1991-10-29 | Sclavo Spa | Metodo per la immunolocalizzazione di antigeni con l'impiego di anticorpi diretti contro epitopi di natura non glucidica |
| DE3829245A1 (de) * | 1988-08-29 | 1990-03-01 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung einer spezifisch bindefaehigen substanz |
| DE3900639A1 (de) * | 1988-12-23 | 1990-06-28 | Boehringer Mannheim Gmbh | Verfahren zum nachweis von kohlenhydrathaltigen verbindungen und dazu geeignetes reagenz |
| US5277892A (en) * | 1990-08-08 | 1994-01-11 | Rhomed Incorporated | In vivo lymphocyte tagging |
| IE920778A1 (en) * | 1991-03-12 | 1992-09-23 | Du Pont | Method for specific binding assays using a releasable ligand |
| US5643549A (en) * | 1992-02-20 | 1997-07-01 | Rhomed Incorporated | Leukostimulatory agent for in vivo leukocyte tagging |
| JP3451783B2 (ja) * | 1995-04-18 | 2003-09-29 | 東ソー株式会社 | コリンエステラーゼの測定法及び肝硬変と肝炎の識別法 |
| SE9602545L (sv) * | 1996-06-25 | 1997-12-26 | Michael Mecklenburg | Metod för att diskriminera komplexa biologiska prover |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE343949B (enExample) * | 1966-06-02 | 1972-03-20 | Pharmacia Ab | |
| US4053284A (en) * | 1976-03-10 | 1977-10-11 | Akzona Incorporated | Continuous flow apparatus for biological testing |
| US4098876A (en) * | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
-
1978
- 1978-12-26 US US05/972,696 patent/US4289747A/en not_active Expired - Lifetime
-
1979
- 1979-12-21 DE DE19792951678 patent/DE2951678A1/de not_active Withdrawn
- 1979-12-26 JP JP17017979A patent/JPS5593063A/ja active Granted
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0033437A1 (de) * | 1980-02-02 | 1981-08-12 | MERCK PATENT GmbH | Verfahren und Mittel zur Bestimmung einer Komponente aus einer Gruppe bestehend aus spezifisch bindende Rezeptoren und Substanzen, die von diesen Rezeptoren spezifisch gebunden werden können |
| EP0041426A1 (fr) * | 1980-05-22 | 1981-12-09 | Institut Pasteur | Produit de couplage entre une lectine et un ligand spécifique, obtention et application dans le domaine biologique |
| EP0043359A3 (en) * | 1980-06-30 | 1982-01-20 | Pharmacia Diagnostics Ab | Determination of terminal saccharide groups in glycoprotein |
| WO1982000204A1 (en) * | 1980-06-30 | 1982-01-21 | Cerven E | Lectin immunoassay for the determination of terminal saccharide groups in glycoprotein |
| EP0201079A3 (en) * | 1985-05-07 | 1989-05-24 | Richard Zahradnik | Delayed solid phase immunologic assay |
| EP0628315A1 (en) * | 1986-03-20 | 1994-12-14 | Dana-Farber Cancer Institute, Inc. | Lectin complex and probe and method for making same |
| EP0353895A1 (en) * | 1988-07-18 | 1990-02-07 | MITSUI TOATSU CHEMICALS, Inc. | Immunoassay method |
| EP0441470A3 (en) * | 1990-01-09 | 1993-02-03 | Wako Pure Chemical Industries Ltd | Process for separating and measuring trace components |
| US5780247A (en) * | 1990-01-09 | 1998-07-14 | Wako Pure Chemical Industries, Ltd. | Process for separating and measuring trace components |
Also Published As
| Publication number | Publication date |
|---|---|
| US4289747A (en) | 1981-09-15 |
| JPS6343711B2 (enExample) | 1988-09-01 |
| JPS5593063A (en) | 1980-07-15 |
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