JPS5593063A - Immunological measurement using lectin - Google Patents

Immunological measurement using lectin

Info

Publication number
JPS5593063A
JPS5593063A JP17017979A JP17017979A JPS5593063A JP S5593063 A JPS5593063 A JP S5593063A JP 17017979 A JP17017979 A JP 17017979A JP 17017979 A JP17017979 A JP 17017979A JP S5593063 A JPS5593063 A JP S5593063A
Authority
JP
Japan
Prior art keywords
lectin
immunological measurement
immunological
measurement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP17017979A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6343711B2 (enExample
Inventor
Ii Chiyuu Arubaato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
E-Y Laboratories Inc
Original Assignee
E-Y Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E-Y Laboratories Inc filed Critical E-Y Laboratories Inc
Publication of JPS5593063A publication Critical patent/JPS5593063A/ja
Publication of JPS6343711B2 publication Critical patent/JPS6343711B2/ja
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/5375—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by changing the physical or chemical properties of the medium or immunochemicals, e.g. temperature, density, pH, partitioning
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/04—Sandwich assay format

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP17017979A 1978-12-26 1979-12-26 Immunological measurement using lectin Granted JPS5593063A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/972,696 US4289747A (en) 1978-12-26 1978-12-26 Immunological determination using lectin

Publications (2)

Publication Number Publication Date
JPS5593063A true JPS5593063A (en) 1980-07-15
JPS6343711B2 JPS6343711B2 (enExample) 1988-09-01

Family

ID=25520012

Family Applications (1)

Application Number Title Priority Date Filing Date
JP17017979A Granted JPS5593063A (en) 1978-12-26 1979-12-26 Immunological measurement using lectin

Country Status (3)

Country Link
US (1) US4289747A (enExample)
JP (1) JPS5593063A (enExample)
DE (1) DE2951678A1 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57161647A (en) * 1981-03-13 1982-10-05 David S Bauman Analyzing apparatus and method
JPS5862563A (ja) * 1981-09-16 1983-04-14 テバ・フア−マシユ−テイカル・インダストリ−ズ・リミテツド 妊娠検出用試薬
JPS60501573A (ja) * 1983-06-10 1985-09-19 エ−ル ユニバ−シテイ 新規な視覚化ポリマ−及びこれらのポリマ−の診断薬への応用
JPS60502039A (ja) * 1983-08-19 1985-11-28 バクスタ−、インタ−ナショナル、インコ−ポレイテッド 抗バクテリア放射線を提供するための装置
JPH02107966A (ja) * 1988-08-29 1990-04-19 Boehringer Mannheim Gmbh 特異的に結合性の物質の測定法及び測定試薬

Families Citing this family (100)

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US4493793A (en) * 1978-12-26 1985-01-15 E-Y Laboratories Soluble immunoassay reagent comprising lectin covalently bonded to reactive component
US4371515A (en) * 1978-12-26 1983-02-01 E-Y Laboratories, Inc. Method for forming an isolated lectin-immunological conjugate
GB2043890B (en) * 1979-01-30 1983-09-07 Otsuka Pharma Co Ltd Determination of tumour associated glycolinkage and diagnosis of cancer
DE3003836A1 (de) * 1980-02-02 1981-08-13 Merck Patent Gmbh, 6100 Darmstadt Verfahren und mittel zur bestimmung einer komponente aus einer gruppe bestehend aus spezifisch bindenden rezeptoren und substanzen, die von diesen rezeptoren spezifisch gebunden werden koennen
DE3172879D1 (en) * 1980-05-22 1985-12-19 Pasteur Institut Coupled product between a lectin and a specific ligand, obtention and use in the biological field
SE447028B (sv) * 1980-06-30 1986-10-20 Erik Audunn Cerven Bestemning av endstaende sackaridgrupper i glykoprotein
JPS5729949A (en) * 1980-07-30 1982-02-18 Nippon Koutai Kenkyusho:Kk Determination of sugar branch related to cancer and diagnostic technique of cancer
US4446314A (en) * 1980-09-30 1984-05-01 Cutter Laboratories, Inc. Fractionation of heparin
US4450104A (en) * 1980-09-30 1984-05-22 Cutter Laboratories, Inc. Water insoluble gel matrix containing lectin bound to antithrombin
US4330299A (en) * 1981-03-09 1982-05-18 Evreka, Inc. Article and method for measuring glucose level in body fluids
FR2520877B1 (fr) * 1982-01-29 1987-07-03 Otsuka Pharma Co Ltd Procede pour la determination des composes a liaisons gluco associes aux tumeurs
CH653442A5 (en) * 1982-01-29 1985-12-31 Otsuka Pharma Co Ltd Process for the determination of tumour-associated glucoside derivatives
US4504585A (en) * 1982-04-05 1985-03-12 Aalto Scientific, Ltd. Affinity immunoassay system
US4530900A (en) * 1982-09-13 1985-07-23 Seragen Diagnostics Inc. Soluble insoluble polymers in enzymeimmunoassay
WO1984002193A1 (en) * 1982-12-03 1984-06-07 Du Pont Chromogenic support immunoassay
WO1985001442A1 (en) * 1983-09-28 1985-04-11 Summa Medical Corporation Lectin composition and method for diagnosis of cancer
FI852545L (fi) * 1984-06-29 1985-12-30 Ortho Diagnostic Systems Inc Sandwichanalys av antikroppslektin.
US4737453A (en) * 1984-12-12 1988-04-12 Immunomedics, Inc. Sandwich immunoassay utilizing a separation specific binding substance
DE3679690D1 (de) * 1985-03-19 1991-07-18 Abbott Lab Diagnostische probe, die mikroperoxidase verwendet.
US4935339A (en) * 1985-05-07 1990-06-19 Nichols Institute Diagnostics Delayed solid phase immunologic assay
US4746631A (en) * 1985-05-09 1988-05-24 Ultra Diagnostics Corporation Immunoassay method, device, and test kit
US4803170A (en) * 1985-05-09 1989-02-07 Ultra Diagnostics Corporation Competitive immunoassay method, device and test kit
US4806311A (en) * 1985-08-28 1989-02-21 Miles Inc. Multizone analytical element having labeled reagent concentration zone
US4933275A (en) * 1985-10-24 1990-06-12 The General Hospital Corporation Method for the detection of a polypeptide subunit in the presence of a quaternary protein containing the subunit
US5239062A (en) * 1986-03-20 1993-08-24 Dana-Farber Cancer Institute, Inc. Blocked lectins, methods and affinity support for making same using affinity ligands, and method of killing selected cell populations having reduced nonselective cytotoxicity
EP0261225B1 (en) * 1986-03-20 1995-09-27 Dana-Farber Cancer Institute, Inc. Lectin complex and method and probe for making same
US5395924A (en) * 1986-03-20 1995-03-07 Dana-Farber Cancer Institute, Inc. Blocked lectins; methods and affinity support for making the same using affinity ligands; and method of killing selected cell populations having reduced non-selective cytotoxicity
US5494800A (en) * 1987-01-29 1996-02-27 Cytosignet, Inc. Analyte detection in particulate-containing samples
IT1230673B (it) * 1987-09-04 1991-10-29 Sclavo Spa Metodo per la immunolocalizzazione di antigeni con l'impiego di anticorpi diretti contro epitopi di natura non glucidica
EP0353895A1 (en) * 1988-07-18 1990-02-07 MITSUI TOATSU CHEMICALS, Inc. Immunoassay method
DE3900639A1 (de) * 1988-12-23 1990-06-28 Boehringer Mannheim Gmbh Verfahren zum nachweis von kohlenhydrathaltigen verbindungen und dazu geeignetes reagenz
EP0441470B1 (en) * 1990-01-09 1995-12-20 Wako Pure Chemical Industries Ltd Process for separating and measuring trace components
US5277892A (en) * 1990-08-08 1994-01-11 Rhomed Incorporated In vivo lymphocyte tagging
IE920778A1 (en) * 1991-03-12 1992-09-23 Du Pont Method for specific binding assays using a releasable ligand
US5643549A (en) * 1992-02-20 1997-07-01 Rhomed Incorporated Leukostimulatory agent for in vivo leukocyte tagging
JP3451783B2 (ja) * 1995-04-18 2003-09-29 東ソー株式会社 コリンエステラーゼの測定法及び肝硬変と肝炎の識別法
SE9602545L (sv) * 1996-06-25 1997-12-26 Michael Mecklenburg Metod för att diskriminera komplexa biologiska prover
US6770453B1 (en) 2000-03-06 2004-08-03 The Regents Of The University Of California Methods of detecting chitinous material in a non-chitinous biological material
US6833250B2 (en) 2000-03-06 2004-12-21 Vicam, L.P. Detection and removal of chitinous material in a biological sample
US7408041B2 (en) * 2000-12-08 2008-08-05 Alexion Pharmaceuticals, Inc. Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
US20060057651A1 (en) * 2000-12-08 2006-03-16 Bowdish Katherine S Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
AU2002246632B2 (en) * 2000-12-08 2007-04-05 Alexion Pharmaceuticals, Inc. Chronic lymphocytic leukemia cell line and its use for producing an antibody
US20040198661A1 (en) * 2000-12-08 2004-10-07 Bowdish Katherine S. Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
US9249229B2 (en) * 2000-12-08 2016-02-02 Alexion Pharmaceuticals, Inc. Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof
CA2447695C (en) 2001-06-01 2015-02-24 Cornell Research Foundation, Inc. Modified antibodies to prostate-specific membrane antigen and uses thereof
CA3050564A1 (en) 2003-08-29 2005-03-10 Dyax Corp. Poly-pegylated protease inhibitors
US7767417B2 (en) * 2004-04-20 2010-08-03 New York University Prenyl-electrostatic switch, and methods of use
US7973134B2 (en) * 2004-07-07 2011-07-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in anaplastic large cell lymphoma signaling pathways
US7527979B2 (en) * 2004-08-18 2009-05-05 Florida State University Research Foundation Devices and methods for rapid detection of pathogens
US7527980B2 (en) * 2004-08-18 2009-05-05 Florida State University Research Foundation Indirect detection of cardiac markers for assessing acute myocardial infarction
US7935790B2 (en) * 2004-10-04 2011-05-03 Cell Singaling Technology, Inc. Reagents for the detection of protein phosphorylation in T-cell receptor signaling pathways
US7807789B2 (en) * 2004-12-21 2010-10-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in EGFR-signaling pathways
EP1868647A4 (en) 2005-03-24 2009-04-01 Millennium Pharm Inc OV064 BINDING ANTIBODIES AND METHOD FOR THEIR USE
US20090099340A1 (en) * 2007-10-12 2009-04-16 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
US20100151495A9 (en) * 2005-08-31 2010-06-17 Cell Signaling Technolgy, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
WO2007027906A2 (en) * 2005-08-31 2007-03-08 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in leukemia signaling pathways
EP2463305B1 (en) * 2006-01-12 2016-05-11 Alexion Pharmaceuticals, Inc. Antibodies to OX-2/CD200 and uses thereof
WO2007127335A2 (en) * 2006-04-27 2007-11-08 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in atm and atr kinase signaling pathways
US7939636B2 (en) * 2006-08-11 2011-05-10 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in c-Src signaling pathways
US20090258442A1 (en) * 2006-08-31 2009-10-15 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
US20090081659A1 (en) 2007-03-07 2009-03-26 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
EP1975184A3 (en) 2007-03-26 2008-11-26 Cell Signaling Technology, Inc. Serine or threonine phosphorylation sites
US20080238709A1 (en) * 2007-03-28 2008-10-02 Faramarz Vaziri One-way communication apparatus with dynamic key generation
CA2682093A1 (en) 2007-03-29 2008-10-09 Technion Research & Development Foundation Ltd. Antibodies, methods and kits for diagnosing and treating melanoma
US7977462B2 (en) 2007-04-19 2011-07-12 Cell Signaling Technology, Inc. Tyrosine phosphorylation sites
EP1983003A3 (en) 2007-04-19 2009-03-11 Peter Hornbeck Tyrosine phosphorylation sites and antibodies specific for them
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CA2694121C (en) * 2007-07-25 2016-06-07 Alexion Pharmaceuticals, Inc. Methods and compositions for treating autoimmune disease
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Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE343949B (enExample) * 1966-06-02 1972-03-20 Pharmacia Ab
US4053284A (en) * 1976-03-10 1977-10-11 Akzona Incorporated Continuous flow apparatus for biological testing
US4098876A (en) * 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57161647A (en) * 1981-03-13 1982-10-05 David S Bauman Analyzing apparatus and method
JPS5862563A (ja) * 1981-09-16 1983-04-14 テバ・フア−マシユ−テイカル・インダストリ−ズ・リミテツド 妊娠検出用試薬
JPS60501573A (ja) * 1983-06-10 1985-09-19 エ−ル ユニバ−シテイ 新規な視覚化ポリマ−及びこれらのポリマ−の診断薬への応用
JPS60502039A (ja) * 1983-08-19 1985-11-28 バクスタ−、インタ−ナショナル、インコ−ポレイテッド 抗バクテリア放射線を提供するための装置
JPH02107966A (ja) * 1988-08-29 1990-04-19 Boehringer Mannheim Gmbh 特異的に結合性の物質の測定法及び測定試薬

Also Published As

Publication number Publication date
US4289747A (en) 1981-09-15
JPS6343711B2 (enExample) 1988-09-01
DE2951678A1 (de) 1980-07-10

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