JPS6248672A - チアゾリジンカルボン酸誘導体 - Google Patents

チアゾリジンカルボン酸誘導体

Info

Publication number
JPS6248672A
JPS6248672A JP61139386A JP13938686A JPS6248672A JP S6248672 A JPS6248672 A JP S6248672A JP 61139386 A JP61139386 A JP 61139386A JP 13938686 A JP13938686 A JP 13938686A JP S6248672 A JPS6248672 A JP S6248672A
Authority
JP
Japan
Prior art keywords
carboxylic acid
thiazolidine
dimethyl
group
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP61139386A
Other languages
English (en)
Japanese (ja)
Inventor
ゾルターン　ジョルジデアーク
イシュトバーン　コバーツ
ラジョー　ボンナール
ゲーザ　ホルバーツ
テレージア　ミレ
ユディト　クルスペル
フェレンツ　プスタイ
マリアン　フェケテ
シャーンドル　ヤンチョー
ヤーノシュ　バーリント
イルディコー　ミホーク
アティラ　ヤカブ
アンドラーシュ　イェネイ
ベーラ　センデ
カーロイ　ラピシュ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Works PLC
Original Assignee
Biogal Gyogyszergyar Rt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Gyogyszergyar Rt filed Critical Biogal Gyogyszergyar Rt
Publication of JPS6248672A publication Critical patent/JPS6248672A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
JP61139386A 1985-06-18 1986-06-17 チアゾリジンカルボン酸誘導体 Pending JPS6248672A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU2251/2388/85 1985-06-18
HU852388A HU200177B (en) 1985-06-18 1985-06-18 Process for producing thiazolidinecarboxylic acids and pharmaceutical compositions comprising such compounds

Publications (1)

Publication Number Publication Date
JPS6248672A true JPS6248672A (ja) 1987-03-03

Family

ID=10959103

Family Applications (1)

Application Number Title Priority Date Filing Date
JP61139386A Pending JPS6248672A (ja) 1985-06-18 1986-06-17 チアゾリジンカルボン酸誘導体

Country Status (21)

Country Link
US (1) US4775675A (ref)
EP (1) EP0206197A1 (ref)
JP (1) JPS6248672A (ref)
KR (1) KR870000312A (ref)
CN (1) CN86104085A (ref)
AR (1) AR241532A1 (ref)
BG (1) BG46457A3 (ref)
DD (1) DD259866A5 (ref)
DK (1) DK259386A (ref)
ES (1) ES8800919A1 (ref)
FI (1) FI862608A7 (ref)
GB (1) GB2177089B (ref)
GR (1) GR861517B (ref)
HU (1) HU200177B (ref)
IL (1) IL78942A0 (ref)
IN (1) IN165646B (ref)
NO (1) NO862408L (ref)
PH (1) PH22790A (ref)
PL (2) PL149453B1 (ref)
PT (1) PT82769B (ref)
SU (2) SU1443800A3 (ref)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5740492A (en) * 1980-08-22 1982-03-06 Yamanouchi Pharmaceut Co Ltd Novel 2-phenylimidazo 2,1-b benzothiazole derivative
US4968708A (en) * 1988-06-22 1990-11-06 Nikken Chemicals Co., Ltd. Imidazo[2,1-B]benzothiazole compounds and antiulcer compositions containing the same
JP2016515531A (ja) * 2013-03-15 2016-05-30 キャンサー リサーチ テクノロジー リミテッド ライアビリティ カンパニー ガンマグルタミル回路調節のための方法および組成物

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1030415A (zh) * 1987-02-20 1989-01-18 山之内制药株式会社 饱和的杂环碳酰胺衍生物和它的制备方法
IT1223565B (it) * 1987-12-21 1990-09-19 Zambon Spa Derivati dell'acido tiazolidin 4 carbossilico ad attivita' farmaceutica
GB9026114D0 (en) * 1990-11-30 1991-01-16 Norsk Hydro As New compounds
ES2092539T3 (es) * 1991-01-10 1996-12-01 Transcend Therapeutics Inc Uso de derivados de la tiazolidina-4-carboxilato para el tratamiento de enfermedades pulmonares.
US5747459A (en) * 1991-02-04 1998-05-05 Nestec, Ltd. Method for insuring adequate intracellular glutathione in tissue
US5849686A (en) * 1991-03-11 1998-12-15 Creative Biomolecules, Inc. Morphogen-induced liver regeneration
US5214062A (en) * 1992-04-08 1993-05-25 Clintec Nutrition Co. Method and composition for treating immune disorders, inflammation and chronic infections
US5430045A (en) * 1992-04-23 1995-07-04 Free Radical Sciences, Inc. Method of reducing or preventing bone marrow hypoplasia
US5447712A (en) * 1993-12-09 1995-09-05 Free Radical Sciences Method of reducing cyclophosphamide induced hemorrhagic cystitis
US6083966A (en) 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
EP1143951A3 (en) * 1998-09-21 2002-02-06 University Of Florida Research Foundation, Inc. Antimalarial agents
WO2000073269A2 (en) 1999-06-02 2000-12-07 Regents Of The University Of Minnesota Nicotine receptor ligands
WO2001012166A2 (en) 1999-08-17 2001-02-22 University Of Saskatchewan Technologies Inc. Improved treatment for acute physical insult to the central nervous system
AU2003270473A1 (en) * 2003-09-09 2005-04-27 University Of Florida Desferrithiocin derivatives and their use as iron chelators
DE102004021658A1 (de) * 2004-05-03 2005-12-01 Rudy Dr. Susilo Kombinationspräparate enthaltend 2-Methylthiazolidin-2,4-dicarbonsäure
MX2007012226A (es) 2005-04-04 2007-12-10 Univ Florida Analogos de polieter de desferritiocina.
WO2008115433A1 (en) * 2007-03-15 2008-09-25 University Of Florida Desferrithiocin polyether analogues
BR112014014544A2 (pt) 2011-12-16 2017-06-13 Univ Florida usos de análogos de 4'-desferritiocina
WO2015077655A1 (en) 2013-11-22 2015-05-28 University Of Florida Research Foundation, Inc. Desferrithiocin analogs and uses thereof
US10570104B2 (en) 2015-04-27 2020-02-25 University Of Florida Research Foundation, Incorporated Metabolically programmed metal chelators and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR923562A (fr) * 1946-02-01 1947-07-10 Tube électronique
CH540234A (de) * 1968-09-06 1973-08-15 Degussa Verfahren zur Herstellung von Penicillamin
ES381037A1 (es) * 1969-06-05 1973-07-01 Ferlux Acido tiazolidin dicarboxilico-2,4 y sus derivados y proce-dimiento para su obtencion.
DE2116629A1 (en) * 1971-04-05 1972-10-19 Institutul de Biochimie, Bukarest 4-thiazolidinecarboxylic acid derivs - with in vivo thiol liberating activity
CA962269A (en) * 1971-05-05 1975-02-04 Uniroyal Ltd. Thiazoles, and their use as insecticides
US3947464A (en) * 1972-07-28 1976-03-30 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler Salts of phenylpropanolamine with thiazolidine carboxylic acids
DE2446100C3 (de) * 1974-09-26 1982-01-14 Ludwig Merckle Kg Chem. Pharm. Fabrik, 7902 Blaubeuren Phenoxyalkancarbonsäureamide von Thiazolidincarbonsäuren, Verfahren zu ihrer Herstellung und Arzneimittel
GB1473752A (en) * 1975-04-09 1977-05-18 Rexolin Chem Ab Composition of nitrofurans and its use in controlling formation of slime
FR2356423A1 (fr) * 1976-07-01 1978-01-27 Oeriu Simion Derives de l'acide thiazolidinecarboxylique, leur preparation et leur application comme medicaments
EP0045281B1 (de) * 1980-07-28 1985-05-08 Ciba-Geigy Ag Thiazolinderivate und Verfahren zu ihrer Herstellung

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5740492A (en) * 1980-08-22 1982-03-06 Yamanouchi Pharmaceut Co Ltd Novel 2-phenylimidazo 2,1-b benzothiazole derivative
US4968708A (en) * 1988-06-22 1990-11-06 Nikken Chemicals Co., Ltd. Imidazo[2,1-B]benzothiazole compounds and antiulcer compositions containing the same
JP2016515531A (ja) * 2013-03-15 2016-05-30 キャンサー リサーチ テクノロジー リミテッド ライアビリティ カンパニー ガンマグルタミル回路調節のための方法および組成物
JP2019065031A (ja) * 2013-03-15 2019-04-25 キャンサー リサーチ テクノロジー リミテッド ライアビリティ カンパニー ガンマグルタミル回路調節のための方法および組成物

Also Published As

Publication number Publication date
GB2177089B (en) 1989-07-19
KR870000312A (ko) 1987-02-17
IN165646B (ref) 1989-12-02
GB8614616D0 (en) 1986-07-23
SU1475905A1 (ru) 1989-04-30
PH22790A (en) 1988-12-12
FI862608A7 (fi) 1986-12-19
BG46457A3 (bg) 1989-12-15
EP0206197A1 (de) 1986-12-30
DD259866A5 (de) 1988-09-07
GB2177089A (en) 1987-01-14
HUT41774A (en) 1987-05-28
US4775675A (en) 1988-10-04
GR861517B (en) 1986-10-10
ES556135A0 (es) 1987-12-01
SU1443800A3 (ru) 1988-12-07
IL78942A0 (en) 1986-09-30
ES8800919A1 (es) 1987-12-01
PL149453B1 (en) 1990-02-28
HU200177B (en) 1990-04-28
NO862408D0 (no) 1986-06-17
DK259386D0 (da) 1986-06-02
PT82769B (pt) 1988-04-21
PT82769A (en) 1986-07-01
AR241532A1 (es) 1992-08-31
FI862608A0 (fi) 1986-06-18
PL148541B1 (en) 1989-10-31
CN86104085A (zh) 1987-04-22
NO862408L (no) 1986-12-19
DK259386A (da) 1986-12-19

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