AR241532A1 - Procedimiento para preparar nuevos derivados de acido-tiazolidin-4(s)-carboxilico. - Google Patents
Procedimiento para preparar nuevos derivados de acido-tiazolidin-4(s)-carboxilico.Info
- Publication number
- AR241532A1 AR241532A1 AR86304306A AR30430686A AR241532A1 AR 241532 A1 AR241532 A1 AR 241532A1 AR 86304306 A AR86304306 A AR 86304306A AR 30430686 A AR30430686 A AR 30430686A AR 241532 A1 AR241532 A1 AR 241532A1
- Authority
- AR
- Argentina
- Prior art keywords
- ilo
- alkyl
- preparation
- acid derivatives
- replaced
- Prior art date
Links
- PMQQFSDIECYOQV-BYPYZUCNSA-N (4s)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid Chemical class CC1(C)SCN[C@H]1C(O)=O PMQQFSDIECYOQV-BYPYZUCNSA-N 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- -1 CHLOROPHENOXY Chemical class 0.000 abstract 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical class O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical group [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003377 acid catalyst Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical group [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- DZLNHFMRPBPULJ-UHFFFAOYSA-N thioproline Chemical compound OC(=O)C1CSCN1 DZLNHFMRPBPULJ-UHFFFAOYSA-N 0.000 abstract 1
- 229950001139 timonacic Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU852388A HU200177B (en) | 1985-06-18 | 1985-06-18 | Process for producing thiazolidinecarboxylic acids and pharmaceutical compositions comprising such compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR241532A1 true AR241532A1 (es) | 1992-08-31 |
Family
ID=10959103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR86304306A AR241532A1 (es) | 1985-06-18 | 1986-06-18 | Procedimiento para preparar nuevos derivados de acido-tiazolidin-4(s)-carboxilico. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4775675A (ref) |
| EP (1) | EP0206197A1 (ref) |
| JP (1) | JPS6248672A (ref) |
| KR (1) | KR870000312A (ref) |
| CN (1) | CN86104085A (ref) |
| AR (1) | AR241532A1 (ref) |
| BG (1) | BG46457A3 (ref) |
| DD (1) | DD259866A5 (ref) |
| DK (1) | DK259386A (ref) |
| ES (1) | ES8800919A1 (ref) |
| FI (1) | FI862608A7 (ref) |
| GB (1) | GB2177089B (ref) |
| GR (1) | GR861517B (ref) |
| HU (1) | HU200177B (ref) |
| IL (1) | IL78942A0 (ref) |
| IN (1) | IN165646B (ref) |
| NO (1) | NO862408L (ref) |
| PH (1) | PH22790A (ref) |
| PL (2) | PL149453B1 (ref) |
| PT (1) | PT82769B (ref) |
| SU (2) | SU1443800A3 (ref) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5740492A (en) * | 1980-08-22 | 1982-03-06 | Yamanouchi Pharmaceut Co Ltd | Novel 2-phenylimidazo 2,1-b benzothiazole derivative |
| CN1030415A (zh) * | 1987-02-20 | 1989-01-18 | 山之内制药株式会社 | 饱和的杂环碳酰胺衍生物和它的制备方法 |
| IT1223565B (it) * | 1987-12-21 | 1990-09-19 | Zambon Spa | Derivati dell'acido tiazolidin 4 carbossilico ad attivita' farmaceutica |
| JP2726999B2 (ja) * | 1988-06-22 | 1998-03-11 | 日研化学株式会社 | イミダゾ［２，１−ｂ］ベンゾチアゾール誘導体及び該化合物を有効成分とする抗潰瘍剤 |
| GB9026114D0 (en) * | 1990-11-30 | 1991-01-16 | Norsk Hydro As | New compounds |
| ES2092539T3 (es) * | 1991-01-10 | 1996-12-01 | Transcend Therapeutics Inc | Uso de derivados de la tiazolidina-4-carboxilato para el tratamiento de enfermedades pulmonares. |
| US5747459A (en) * | 1991-02-04 | 1998-05-05 | Nestec, Ltd. | Method for insuring adequate intracellular glutathione in tissue |
| US5849686A (en) * | 1991-03-11 | 1998-12-15 | Creative Biomolecules, Inc. | Morphogen-induced liver regeneration |
| US5214062A (en) * | 1992-04-08 | 1993-05-25 | Clintec Nutrition Co. | Method and composition for treating immune disorders, inflammation and chronic infections |
| US5430045A (en) * | 1992-04-23 | 1995-07-04 | Free Radical Sciences, Inc. | Method of reducing or preventing bone marrow hypoplasia |
| US5447712A (en) * | 1993-12-09 | 1995-09-05 | Free Radical Sciences | Method of reducing cyclophosphamide induced hemorrhagic cystitis |
| US6083966A (en) | 1998-08-31 | 2000-07-04 | University Of Florida | Thiazoline acid derivatives |
| EP1143951A3 (en) * | 1998-09-21 | 2002-02-06 | University Of Florida Research Foundation, Inc. | Antimalarial agents |
| WO2000073269A2 (en) | 1999-06-02 | 2000-12-07 | Regents Of The University Of Minnesota | Nicotine receptor ligands |
| WO2001012166A2 (en) | 1999-08-17 | 2001-02-22 | University Of Saskatchewan Technologies Inc. | Improved treatment for acute physical insult to the central nervous system |
| AU2003270473A1 (en) * | 2003-09-09 | 2005-04-27 | University Of Florida | Desferrithiocin derivatives and their use as iron chelators |
| DE102004021658A1 (de) * | 2004-05-03 | 2005-12-01 | Rudy Dr. Susilo | Kombinationspräparate enthaltend 2-Methylthiazolidin-2,4-dicarbonsäure |
| MX2007012226A (es) | 2005-04-04 | 2007-12-10 | Univ Florida | Analogos de polieter de desferritiocina. |
| WO2008115433A1 (en) * | 2007-03-15 | 2008-09-25 | University Of Florida | Desferrithiocin polyether analogues |
| BR112014014544A2 (pt) | 2011-12-16 | 2017-06-13 | Univ Florida | usos de análogos de 4'-desferritiocina |
| KR20160003652A (ko) * | 2013-03-15 | 2016-01-11 | 캔써 리써치 테크놀로지, 엘엘씨 | 감마―글루타밀 주기 조절 방법 및 조성물 |
| WO2015077655A1 (en) | 2013-11-22 | 2015-05-28 | University Of Florida Research Foundation, Inc. | Desferrithiocin analogs and uses thereof |
| US10570104B2 (en) | 2015-04-27 | 2020-02-25 | University Of Florida Research Foundation, Incorporated | Metabolically programmed metal chelators and uses thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR923562A (fr) * | 1946-02-01 | 1947-07-10 | Tube électronique | |
| CH540234A (de) * | 1968-09-06 | 1973-08-15 | Degussa | Verfahren zur Herstellung von Penicillamin |
| ES381037A1 (es) * | 1969-06-05 | 1973-07-01 | Ferlux | Acido tiazolidin dicarboxilico-2,4 y sus derivados y proce-dimiento para su obtencion. |
| DE2116629A1 (en) * | 1971-04-05 | 1972-10-19 | Institutul de Biochimie, Bukarest | 4-thiazolidinecarboxylic acid derivs - with in vivo thiol liberating activity |
| CA962269A (en) * | 1971-05-05 | 1975-02-04 | Uniroyal Ltd. | Thiazoles, and their use as insecticides |
| US3947464A (en) * | 1972-07-28 | 1976-03-30 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler | Salts of phenylpropanolamine with thiazolidine carboxylic acids |
| DE2446100C3 (de) * | 1974-09-26 | 1982-01-14 | Ludwig Merckle Kg Chem. Pharm. Fabrik, 7902 Blaubeuren | Phenoxyalkancarbonsäureamide von Thiazolidincarbonsäuren, Verfahren zu ihrer Herstellung und Arzneimittel |
| GB1473752A (en) * | 1975-04-09 | 1977-05-18 | Rexolin Chem Ab | Composition of nitrofurans and its use in controlling formation of slime |
| FR2356423A1 (fr) * | 1976-07-01 | 1978-01-27 | Oeriu Simion | Derives de l'acide thiazolidinecarboxylique, leur preparation et leur application comme medicaments |
| EP0045281B1 (de) * | 1980-07-28 | 1985-05-08 | Ciba-Geigy Ag | Thiazolinderivate und Verfahren zu ihrer Herstellung |
-
1985
- 1985-06-18 HU HU852388A patent/HU200177B/hu not_active IP Right Cessation
-
1986
- 1986-05-27 IL IL78942A patent/IL78942A0/xx unknown
- 1986-06-02 DK DK259386A patent/DK259386A/da not_active Application Discontinuation
- 1986-06-04 IN IN416/CAL/86A patent/IN165646B/en unknown
- 1986-06-05 PH PH33857A patent/PH22790A/en unknown
- 1986-06-11 GR GR861517A patent/GR861517B/el unknown
- 1986-06-13 US US06/874,111 patent/US4775675A/en not_active Expired - Fee Related
- 1986-06-16 GB GB8614616A patent/GB2177089B/en not_active Expired
- 1986-06-16 PT PT82769A patent/PT82769B/pt not_active IP Right Cessation
- 1986-06-16 PL PL1986273754A patent/PL149453B1/pl unknown
- 1986-06-16 PL PL1986260106A patent/PL148541B1/pl unknown
- 1986-06-16 DD DD86291335A patent/DD259866A5/de not_active IP Right Cessation
- 1986-06-17 JP JP61139386A patent/JPS6248672A/ja active Pending
- 1986-06-17 ES ES556135A patent/ES8800919A1/es not_active Expired
- 1986-06-17 NO NO862408A patent/NO862408L/no unknown
- 1986-06-18 FI FI862608A patent/FI862608A7/fi not_active Application Discontinuation
- 1986-06-18 AR AR86304306A patent/AR241532A1/es active
- 1986-06-18 KR KR1019860004835A patent/KR870000312A/ko not_active Abandoned
- 1986-06-18 EP EP86108186A patent/EP0206197A1/de active Pending
- 1986-06-18 BG BG075405A patent/BG46457A3/xx unknown
- 1986-06-18 CN CN198686104085A patent/CN86104085A/zh active Pending
- 1986-06-18 SU SU864027696A patent/SU1443800A3/ru active
- 1986-11-19 SU SU864028509A patent/SU1475905A1/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| GB2177089B (en) | 1989-07-19 |
| KR870000312A (ko) | 1987-02-17 |
| IN165646B (ref) | 1989-12-02 |
| GB8614616D0 (en) | 1986-07-23 |
| SU1475905A1 (ru) | 1989-04-30 |
| PH22790A (en) | 1988-12-12 |
| FI862608A7 (fi) | 1986-12-19 |
| BG46457A3 (bg) | 1989-12-15 |
| EP0206197A1 (de) | 1986-12-30 |
| DD259866A5 (de) | 1988-09-07 |
| GB2177089A (en) | 1987-01-14 |
| HUT41774A (en) | 1987-05-28 |
| US4775675A (en) | 1988-10-04 |
| GR861517B (en) | 1986-10-10 |
| ES556135A0 (es) | 1987-12-01 |
| SU1443800A3 (ru) | 1988-12-07 |
| IL78942A0 (en) | 1986-09-30 |
| ES8800919A1 (es) | 1987-12-01 |
| PL149453B1 (en) | 1990-02-28 |
| HU200177B (en) | 1990-04-28 |
| NO862408D0 (no) | 1986-06-17 |
| DK259386D0 (da) | 1986-06-02 |
| PT82769B (pt) | 1988-04-21 |
| JPS6248672A (ja) | 1987-03-03 |
| PT82769A (en) | 1986-07-01 |
| FI862608A0 (fi) | 1986-06-18 |
| PL148541B1 (en) | 1989-10-31 |
| CN86104085A (zh) | 1987-04-22 |
| NO862408L (no) | 1986-12-19 |
| DK259386A (da) | 1986-12-19 |
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