JPS6121957B2 - - Google Patents

Info

Publication number
JPS6121957B2
JPS6121957B2 JP51069658A JP6965876A JPS6121957B2 JP S6121957 B2 JPS6121957 B2 JP S6121957B2 JP 51069658 A JP51069658 A JP 51069658A JP 6965876 A JP6965876 A JP 6965876A JP S6121957 B2 JPS6121957 B2 JP S6121957B2
Authority
JP
Japan
Prior art keywords
formula
piperidinylidene
group
lower alkyl
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP51069658A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5236683A (en
Inventor
Marushiirii Reonarudo
Rozetsutei Bitsutorio
Pasukuarushii Karumine
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AACHIFUA IND CHIMICHE DERU TORENCHINO SpA
Original Assignee
AACHIFUA IND CHIMICHE DERU TORENCHINO SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AACHIFUA IND CHIMICHE DERU TORENCHINO SpA filed Critical AACHIFUA IND CHIMICHE DERU TORENCHINO SpA
Publication of JPS5236683A publication Critical patent/JPS5236683A/ja
Publication of JPS6121957B2 publication Critical patent/JPS6121957B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP51069658A 1975-06-13 1976-06-14 Production of riphamycin Granted JPS5236683A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT755174A IT1056272B (it) 1975-06-13 1975-06-13 Prodotti derivati dalle amine aromatiche

Publications (2)

Publication Number Publication Date
JPS5236683A JPS5236683A (en) 1977-03-22
JPS6121957B2 true JPS6121957B2 (enExample) 1986-05-29

Family

ID=11118842

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51069658A Granted JPS5236683A (en) 1975-06-13 1976-06-14 Production of riphamycin

Country Status (28)

Country Link
US (2) US4086225A (enExample)
JP (1) JPS5236683A (enExample)
AR (1) AR211127A1 (enExample)
AU (1) AU497602B2 (enExample)
BE (1) BE842883A (enExample)
CA (1) CA1059123A (enExample)
CH (1) CH625524A5 (enExample)
CS (1) CS197271B1 (enExample)
DK (1) DK145228C (enExample)
ES (1) ES449187A1 (enExample)
FI (1) FI60208C (enExample)
FR (1) FR2314189A1 (enExample)
GB (1) GB1542063A (enExample)
HK (1) HK56083A (enExample)
HU (1) HU171396B (enExample)
IE (1) IE42998B1 (enExample)
IL (1) IL49701A (enExample)
IN (1) IN143526B (enExample)
IT (1) IT1056272B (enExample)
NL (1) NL177919C (enExample)
NO (1) NO148848C (enExample)
PH (1) PH16410A (enExample)
PL (1) PL99493B1 (enExample)
PT (1) PT65208B (enExample)
SE (1) SE434057B (enExample)
SU (1) SU680649A3 (enExample)
YU (1) YU39768B (enExample)
ZA (1) ZA763256B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1056272B (it) * 1975-06-13 1982-01-30 Archifar Ind Chim Trentino Prodotti derivati dalle amine aromatiche
DK345977A (da) * 1976-09-30 1978-03-31 Archifar Ind Chim Trentino G rifamycinforbindelser og fremgangsmaade til deres fremstillin
BE886395A (fr) * 1980-02-13 1981-03-16 Erba Farmitalia Derives de rifamycine
IT1201963B (it) * 1983-03-24 1989-02-02 Prodotti Antibiotici Spa Derivati delle rifamicine e procedimento per la loro preparazione
US4631290A (en) * 1985-08-29 1986-12-23 American Home Products Corporation Method of treating hepatitis
DE69400631T2 (de) * 1993-05-05 1997-02-27 Palo Alto Medical Foundation, Palo Alto, Calif. Verwendung von rifamycinderivaten zur herstellung eines arzneimittels zur behandlung der toxoplasmose
US5529994A (en) * 1993-05-05 1996-06-25 Palo Alto Medical Foundation Treatment for toxoplasmosis
US5981522A (en) * 1995-09-01 1999-11-09 Kaneka Corporation Treatment of disease caused by infection of Helicobacter
EP0787494B1 (en) * 1995-09-01 2004-06-09 Kaneka Corporation Use of rifamycin derivatives for the manufacture of a medicament for the treatment of diseases caused by infections of helicobacter pylori
JP2005510534A (ja) * 2001-11-21 2005-04-21 アクティブバイオティクス インコーポレイティッド 標的化治療薬およびその使用
WO2003051299A2 (en) * 2001-12-13 2003-06-26 Activbiotics, Inc. Sulfhydryl rifamycins and uses thereof
US7820652B2 (en) * 2003-09-24 2010-10-26 Activbiotics Pharma, Llc Regimen for the administration of rifamycin-class antibiotics
US7202246B2 (en) * 2004-06-09 2007-04-10 Cumbre Pharmaceuticals Inc. Spiro-rifamycin derivatives targeting RNA polymerase
ES2246155B1 (es) * 2004-07-19 2007-03-16 Universidad De Oviedo Nuevas espiropiperidilrifamicinas.
EP1928890B1 (en) 2005-08-11 2013-04-03 Targanta Therapeutics Inc. Phosphonated rifamycins and uses thereof for the prevention and treatment of bone and joint infections
WO2008008480A2 (en) * 2006-07-12 2008-01-17 Cumbre Pharmaceuticals Inc. Nitroheteroaryl-containing rifamycin derivatives
CN100569778C (zh) * 2006-12-05 2009-12-16 四川明欣药业有限责任公司 一种利福布汀结晶工艺
WO2009064792A1 (en) * 2007-11-16 2009-05-22 Cumbre Pharmaceuticals Inc. Quinolone carboxylic acid-substituted rifamycin derivatives
US8524691B2 (en) 2008-08-13 2013-09-03 The Medicines Company Phosphonated rifamycins and uses thereof for the prevention and treatment of bone and joint infections
MX370688B (es) 2012-08-30 2019-12-19 Texas A & M Univ Sys Composiciones y métodos para sensibilización con fármaco o inhibición de una célula de cáncer.
PH12013000351A1 (en) 2013-11-22 2015-05-25 Joselle A Macrohon A versatile queuing management system and method
JP6867288B2 (ja) 2014-07-21 2021-04-28 エーエムディー セラピューティックス エルエルシー リファマイシンの眼科用組成物およびその使用
CN106279205B (zh) * 2015-05-12 2020-07-21 重庆华邦胜凯制药有限公司 制备利福霉素s衍生物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL130099C (enExample) * 1963-10-11
IT1056272B (it) * 1975-06-13 1982-01-30 Archifar Ind Chim Trentino Prodotti derivati dalle amine aromatiche
DE2626296C2 (de) * 1975-06-13 1986-11-27 Farmitalia Carlo Erba S.p.A., Mailand/Milano Rifamycin-Verbindung und Verfahren zu seiner Herstellung

Also Published As

Publication number Publication date
PL99493B1 (pl) 1978-07-31
FI60208C (fi) 1981-12-10
HU171396B (hu) 1978-01-28
GB1542063A (en) 1979-03-14
IT1056272B (it) 1982-01-30
IL49701A0 (en) 1976-08-31
BE842883A (fr) 1976-10-01
SU680649A3 (ru) 1979-08-15
US4086225A (en) 1978-04-25
DK145228C (da) 1983-02-28
FR2314189A1 (fr) 1977-01-07
YU39768B (en) 1985-04-30
FI761688A7 (enExample) 1976-12-14
FI60208B (fi) 1981-08-31
AU497602B2 (en) 1978-12-21
IN143526B (enExample) 1977-12-17
NL7606370A (nl) 1976-12-15
NO762026L (enExample) 1976-12-14
ZA763256B (en) 1977-05-25
CA1059123A (en) 1979-07-24
DK258076A (da) 1976-12-14
US4219478A (en) 1980-08-26
AR211127A1 (es) 1977-10-31
IE42998L (en) 1976-12-13
PT65208A (en) 1976-07-01
YU140576A (en) 1982-06-30
CH625524A5 (enExample) 1981-09-30
HK56083A (en) 1983-11-25
SE7606640L (sv) 1976-12-14
SE434057B (sv) 1984-07-02
IE42998B1 (en) 1980-12-03
PT65208B (en) 1977-11-23
NL177919B (nl) 1985-07-16
IL49701A (en) 1979-10-31
JPS5236683A (en) 1977-03-22
NO148848C (no) 1983-12-28
FR2314189B1 (enExample) 1980-10-31
AU1476976A (en) 1977-12-15
NL177919C (nl) 1985-12-16
PH16410A (en) 1983-09-29
NO148848B (no) 1983-09-19
ES449187A1 (es) 1977-07-16
CS197271B1 (en) 1980-04-30
DK145228B (da) 1982-10-11

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