JPS61135597A - シチジンおよびデオキシシチジンの製造法 - Google Patents

シチジンおよびデオキシシチジンの製造法

Info

Publication number
JPS61135597A
JPS61135597A JP59258788A JP25878884A JPS61135597A JP S61135597 A JPS61135597 A JP S61135597A JP 59258788 A JP59258788 A JP 59258788A JP 25878884 A JP25878884 A JP 25878884A JP S61135597 A JPS61135597 A JP S61135597A
Authority
JP
Japan
Prior art keywords
cytidine
deoxycytidine
strain
medium
page
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59258788A
Other languages
English (en)
Japanese (ja)
Other versions
JPH058000B2 (enExample
Inventor
Satoru Asahi
知 朝日
Yutaka Tsunemi
常見　裕
Muneharu Doi
土居　宗晴
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP59258788A priority Critical patent/JPS61135597A/ja
Priority to CN85108240A priority patent/CN1011704B/zh
Priority to US06/802,344 priority patent/US4839285A/en
Priority to CA000496215A priority patent/CA1278541C/en
Priority to EP85115244A priority patent/EP0188708B1/en
Priority to DE8585115244T priority patent/DE3573613D1/de
Priority to AT85115244T priority patent/ATE47154T1/de
Priority to KR1019850009139A priority patent/KR930005869B1/ko
Priority to ES549620A priority patent/ES8701224A1/es
Publication of JPS61135597A publication Critical patent/JPS61135597A/ja
Priority to JP4058429A priority patent/JPH0673452B2/ja
Publication of JPH058000B2 publication Critical patent/JPH058000B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/385—Pyrimidine nucleosides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y10S435/839—Bacillus subtilis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP59258788A 1984-12-06 1984-12-06 シチジンおよびデオキシシチジンの製造法 Granted JPS61135597A (ja)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP59258788A JPS61135597A (ja) 1984-12-06 1984-12-06 シチジンおよびデオキシシチジンの製造法
CN85108240A CN1011704B (zh) 1984-12-06 1985-11-16 胞苷和/或脱氧胞苷的生产方法
US06/802,344 US4839285A (en) 1984-12-06 1985-11-25 Method for production of cytidine and/or deoxycytidine
CA000496215A CA1278541C (en) 1984-12-06 1985-11-26 Method for production of cytidine and/or deoxycytidine
DE8585115244T DE3573613D1 (en) 1984-12-06 1985-11-30 Method for production of cytidine and/or deoxycytidine
EP85115244A EP0188708B1 (en) 1984-12-06 1985-11-30 Method for production of cytidine and/or deoxycytidine
AT85115244T ATE47154T1 (de) 1984-12-06 1985-11-30 Verfahren zur herstellung von cytidin und/oder desoxycytidin.
KR1019850009139A KR930005869B1 (ko) 1984-12-06 1985-12-05 시티딘 및/또는 데옥시시티딘의 제조 방법
ES549620A ES8701224A1 (es) 1984-12-06 1985-12-05 Un metodo para producir citidina y-o desoxicitidina
JP4058429A JPH0673452B2 (ja) 1984-12-06 1992-03-16 新規バチルス・ズブチリス

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59258788A JPS61135597A (ja) 1984-12-06 1984-12-06 シチジンおよびデオキシシチジンの製造法
JP4058429A JPH0673452B2 (ja) 1984-12-06 1992-03-16 新規バチルス・ズブチリス

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP4058429A Division JPH0673452B2 (ja) 1984-12-06 1992-03-16 新規バチルス・ズブチリス

Publications (2)

Publication Number Publication Date
JPS61135597A true JPS61135597A (ja) 1986-06-23
JPH058000B2 JPH058000B2 (enExample) 1993-01-29

Family

ID=26399491

Family Applications (2)

Application Number Title Priority Date Filing Date
JP59258788A Granted JPS61135597A (ja) 1984-12-06 1984-12-06 シチジンおよびデオキシシチジンの製造法
JP4058429A Expired - Lifetime JPH0673452B2 (ja) 1984-12-06 1992-03-16 新規バチルス・ズブチリス

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP4058429A Expired - Lifetime JPH0673452B2 (ja) 1984-12-06 1992-03-16 新規バチルス・ズブチリス

Country Status (7)

Country Link
US (1) US4839285A (enExample)
EP (1) EP0188708B1 (enExample)
JP (2) JPS61135597A (enExample)
KR (1) KR930005869B1 (enExample)
CN (1) CN1011704B (enExample)
CA (1) CA1278541C (enExample)
ES (1) ES8701224A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114929240A (zh) * 2019-08-19 2022-08-19 莫迪斯治疗公司 脱氧胞苷的多晶型形式、包含其的组合物和用途

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH044881A (ja) * 1990-04-23 1992-01-09 Takeda Chem Ind Ltd シチジンアナログ耐性化遺伝子ｄｎａおよびその用途
US6883520B2 (en) * 1999-08-18 2005-04-26 Intrinsic Therapeutics, Inc. Methods and apparatus for dynamically stable spinal implant
CA2380804A1 (en) * 2001-05-01 2002-11-01 Mitsui Chemicals, Inc. Method for producing cytosine nucleosides compounds
WO2010113039A1 (en) * 2009-04-03 2010-10-07 Medical Research Council Mutants of activation-induced cytidine deaminase (aid) and methods of use
CN103088008B (zh) * 2011-10-31 2014-08-20 中国科学院微生物研究所 胞苷脱氨酶及其编码基因和它们的应用
CN105505844B (zh) * 2014-09-24 2019-07-30 中国科学院天津工业生物技术研究所 一种胞苷高产微生物菌株的高通量筛选方法
CN105671007B (zh) * 2015-12-31 2019-03-29 天津科技大学 高产嘧啶核苷的菌株及其氨甲酰磷酸合成酶调节位点
CN105671008B (zh) * 2015-12-31 2019-03-29 天津科技大学 一株高产嘧啶核苷的菌株及其氨甲酰磷酸合成酶调节位点
CN106754602B (zh) * 2017-01-04 2021-08-20 苏州华赛生物工程技术有限公司 一种生产胞苷的重组微生物及生产胞苷的方法
CN109187794B (zh) * 2018-09-27 2021-08-17 南京医科大学 精浆脱氧胞苷和胞苷检测作为特发性男性不育诊断标志物及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1316549A (fr) * 1961-12-14 1963-02-01 Meiji Seika Co Procédé de fabrication de nucléosides et nucléotides
FR1374725A (fr) * 1963-11-12 1964-10-09 Ajinomoto Kk Procédé de préparation de l'orotidine
JPS5230989A (en) * 1975-03-28 1977-03-09 Sugano Seisakusho:Kk Paper feed device for automatic paper punching

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114929240A (zh) * 2019-08-19 2022-08-19 莫迪斯治疗公司 脱氧胞苷的多晶型形式、包含其的组合物和用途

Also Published As

Publication number Publication date
ES549620A0 (es) 1986-11-16
JPH05292945A (ja) 1993-11-09
CN85108240A (zh) 1986-07-02
CA1278541C (en) 1991-01-02
JPH058000B2 (enExample) 1993-01-29
JPH0673452B2 (ja) 1994-09-21
KR860005026A (ko) 1986-07-16
KR930005869B1 (ko) 1993-06-25
CN1011704B (zh) 1991-02-20
EP0188708B1 (en) 1989-10-11
ES8701224A1 (es) 1986-11-16
US4839285A (en) 1989-06-13
EP0188708A1 (en) 1986-07-30

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