ES8701224A1 - Un metodo para producir citidina y-o desoxicitidina - Google Patents

Un metodo para producir citidina y-o desoxicitidina

Info

Publication number
ES8701224A1
ES8701224A1 ES549620A ES549620A ES8701224A1 ES 8701224 A1 ES8701224 A1 ES 8701224A1 ES 549620 A ES549620 A ES 549620A ES 549620 A ES549620 A ES 549620A ES 8701224 A1 ES8701224 A1 ES 8701224A1
Authority
ES
Spain
Prior art keywords
cytidine
deoxycytidine
production
culturing
ability
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES549620A
Other languages
English (en)
Other versions
ES549620A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ES549620A0 publication Critical patent/ES549620A0/es
Publication of ES8701224A1 publication Critical patent/ES8701224A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/385—Pyrimidine nucleosides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y10S435/839—Bacillus subtilis

Abstract

UN METODO PARA PRODUCIR CITIDINA Y/O DESOXICITIDINA, Y UN MICROORGANISMO. SE CULTIVAN MICROBIOS DEFICIENTES EN ACTIVIDAD DE CITIDINO-DEAMINASA, DEL GENERO BACILLUS, RESISTENTES A ANALOGOS DE PIRIMIDINA Y CAPACES DE PRODUCIR CITIDINA Y/O DESOXICITIDINA, EN UN MEDIO PARA RECOGER CITIDINA Y/O DESOXICITIDINA PRODUCIDAS Y ACUMULADAS EN EL CULTIVO. EL METODO ES APLICABLE A LA PRODUCCION INDUSTRIAL DE CITOIDINA Y DESOXICITIDINA DESTINADAS A LA SINTESIS DE MEDICAMENTOS.
ES549620A 1984-12-06 1985-12-05 Un metodo para producir citidina y-o desoxicitidina Expired ES8701224A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59258788A JPS61135597A (ja) 1984-12-06 1984-12-06 シチジンおよびデオキシシチジンの製造法
JP4058429A JPH0673452B2 (ja) 1984-12-06 1992-03-16 新規バチルス・ズブチリス

Publications (2)

Publication Number Publication Date
ES549620A0 ES549620A0 (es) 1986-11-16
ES8701224A1 true ES8701224A1 (es) 1986-11-16

Family

ID=26399491

Family Applications (1)

Application Number Title Priority Date Filing Date
ES549620A Expired ES8701224A1 (es) 1984-12-06 1985-12-05 Un metodo para producir citidina y-o desoxicitidina

Country Status (7)

Country Link
US (1) US4839285A (es)
EP (1) EP0188708B1 (es)
JP (2) JPS61135597A (es)
KR (1) KR930005869B1 (es)
CN (1) CN1011704B (es)
CA (1) CA1278541C (es)
ES (1) ES8701224A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH044881A (ja) * 1990-04-23 1992-01-09 Takeda Chem Ind Ltd シチジンアナログ耐性化遺伝子ｄｎａおよびその用途
US7220281B2 (en) * 1999-08-18 2007-05-22 Intrinsic Therapeutics, Inc. Implant for reinforcing and annulus fibrosis
CA2380804A1 (en) * 2001-05-01 2002-11-01 Mitsui Chemicals, Inc. Method for producing cytosine nucleosides compounds
JP5683566B2 (ja) * 2009-04-03 2015-03-11 メディカル リサーチ カウンシル 活性化誘導シチジンデアミナーゼ（ａｉｄ）の変異体及び使用方法
CN103088008B (zh) * 2011-10-31 2014-08-20 中国科学院微生物研究所 胞苷脱氨酶及其编码基因和它们的应用
CN105505844B (zh) * 2014-09-24 2019-07-30 中国科学院天津工业生物技术研究所 一种胞苷高产微生物菌株的高通量筛选方法
CN105671008B (zh) * 2015-12-31 2019-03-29 天津科技大学 一株高产嘧啶核苷的菌株及其氨甲酰磷酸合成酶调节位点
CN105671007B (zh) * 2015-12-31 2019-03-29 天津科技大学 高产嘧啶核苷的菌株及其氨甲酰磷酸合成酶调节位点
CN106754602B (zh) * 2017-01-04 2021-08-20 苏州华赛生物工程技术有限公司 一种生产胞苷的重组微生物及生产胞苷的方法
CN109187794B (zh) * 2018-09-27 2021-08-17 南京医科大学 精浆脱氧胞苷和胞苷检测作为特发性男性不育诊断标志物及其应用
CN114929240A (zh) * 2019-08-19 2022-08-19 莫迪斯治疗公司 脱氧胞苷的多晶型形式、包含其的组合物和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1316549A (fr) * 1961-12-14 1963-02-01 Meiji Seika Co Procédé de fabrication de nucléosides et nucléotides
FR1374725A (fr) * 1963-11-12 1964-10-09 Ajinomoto Kk Procédé de préparation de l'orotidine
JPS5230989A (en) * 1975-03-28 1977-03-09 Sugano Seisakusho:Kk Paper feed device for automatic paper punching

Also Published As

Publication number Publication date
EP0188708A1 (en) 1986-07-30
CN1011704B (zh) 1991-02-20
US4839285A (en) 1989-06-13
JPH05292945A (ja) 1993-11-09
JPS61135597A (ja) 1986-06-23
ES549620A0 (es) 1986-11-16
CN85108240A (zh) 1986-07-02
EP0188708B1 (en) 1989-10-11
JPH0673452B2 (ja) 1994-09-21
KR860005026A (ko) 1986-07-16
JPH058000B2 (es) 1993-01-29
KR930005869B1 (ko) 1993-06-25
CA1278541C (en) 1991-01-02

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20050923