JPS6033433B2 - ハロゲン置換ベンゾピラン−4−カルボン酸およびその誘導体 - Google Patents

ハロゲン置換ベンゾピラン−4−カルボン酸およびその誘導体

Info

Publication number
JPS6033433B2
JPS6033433B2 JP54144280A JP14428079A JPS6033433B2 JP S6033433 B2 JPS6033433 B2 JP S6033433B2 JP 54144280 A JP54144280 A JP 54144280A JP 14428079 A JP14428079 A JP 14428079A JP S6033433 B2 JPS6033433 B2 JP S6033433B2
Authority
JP
Japan
Prior art keywords
compound according
dihydro
chloro
acid
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP54144280A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5585582A (en
Inventor
ジヨン・エル・ベルテイア
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PFIZER
Original Assignee
PFIZER
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PFIZER filed Critical PFIZER
Publication of JPS5585582A publication Critical patent/JPS5585582A/ja
Publication of JPS6033433B2 publication Critical patent/JPS6033433B2/ja
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06Benzothiopyrans; Hydrogenated benzothiopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/92Naphthopyrans; Hydrogenated naphthopyrans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP54144280A 1978-11-08 1979-11-07 ハロゲン置換ベンゾピラン−4−カルボン酸およびその誘導体 Expired JPS6033433B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/959,023 US4210663A (en) 1978-11-08 1978-11-08 Halogen substituted benzopyran- and benzothiopyran-4-carboxylic acids
US959023 1992-10-09

Publications (2)

Publication Number Publication Date
JPS5585582A JPS5585582A (en) 1980-06-27
JPS6033433B2 true JPS6033433B2 (ja) 1985-08-02

Family

ID=25501572

Family Applications (2)

Application Number Title Priority Date Filing Date
JP54144280A Expired JPS6033433B2 (ja) 1978-11-08 1979-11-07 ハロゲン置換ベンゾピラン−4−カルボン酸およびその誘導体
JP17706780A Granted JPS56103176A (en) 1978-11-08 1980-12-15 Halogen substituted benzothiopyranee44carboxylic acids

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP17706780A Granted JPS56103176A (en) 1978-11-08 1980-12-15 Halogen substituted benzothiopyranee44carboxylic acids

Country Status (16)

Country Link
US (1) US4210663A (2)
EP (1) EP0011426B1 (2)
JP (2) JPS6033433B2 (2)
KR (1) KR830001821B1 (2)
AR (1) AR223195A1 (2)
AT (1) AT366680B (2)
AU (1) AU513399B2 (2)
CA (1) CA1132584A (2)
DE (1) DE2965755D1 (2)
DK (1) DK153947C (2)
ES (1) ES485798A1 (2)
FI (1) FI71139C (2)
IE (1) IE49109B1 (2)
IL (1) IL58656A (2)
PT (1) PT70420A (2)
YU (1) YU41675B (2)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992014439A1 (fr) * 1991-02-18 1992-09-03 Chugai Seiyaku Kabushiki Kaisha Agent stimulant la croissance des cheveux
WO1999043315A1 (en) * 1998-02-25 1999-09-02 Shionogi & Co., Ltd. Therapeutic agent for complication of diabetes

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4305955A (en) * 1980-10-21 1981-12-15 Pfizer Inc. Carboxylic acid therapeutic agents
US4486428A (en) * 1982-03-16 1984-12-04 Pfizer Inc. Bicyclic benzo fused compounds
US4537920A (en) * 1983-08-18 1985-08-27 Ethyl Corporation 4H-1-benzopyrans and lubricant compositions containing same
US4551542A (en) * 1984-09-26 1985-11-05 Pfizer Inc. Regeneration of 6-fluoro-4-chromanone from 6-fluoro-4-ureidochroman-4-carboxylic acid
WO1987004344A1 (en) * 1986-01-17 1987-07-30 Pfizer Inc. Hydroxyacetic acid derivatives for the treatment of diabetic complications
DE3737195A1 (de) * 1987-11-03 1989-05-18 Bayer Ag Chromanderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US5039672A (en) * 1990-04-05 1991-08-13 Pfizer Inc. Heterocyclic compounds as aldose reductase inhibitors
ATE161254T1 (de) * 1990-07-27 1998-01-15 Chugai Pharmaceutical Co Ltd Benzopyranderivat
US5407897A (en) * 1993-03-03 1995-04-18 American Cyanamid Company Method for safening herbicides in crops using substituted benzopyran and tetrahydronaphthalene compounds
US7288279B2 (en) * 2001-12-21 2007-10-30 Michael Foods Of Delaware, Inc. Formulated fried egg product
JP4742215B2 (ja) * 2003-06-23 2011-08-10 Jnc株式会社 クロマン化合物、この化合物を含有する液晶組成物およびこの液晶組成物を含有する液晶表示素子
JP5956920B2 (ja) 2012-12-14 2016-07-27 株式会社コガネイ 液体供給装置

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992014439A1 (fr) * 1991-02-18 1992-09-03 Chugai Seiyaku Kabushiki Kaisha Agent stimulant la croissance des cheveux
WO1999043315A1 (en) * 1998-02-25 1999-09-02 Shionogi & Co., Ltd. Therapeutic agent for complication of diabetes

Also Published As

Publication number Publication date
JPS6113716B2 (2) 1986-04-15
US4210663A (en) 1980-07-01
ATA719279A (de) 1981-09-15
AR223195A1 (es) 1981-07-31
IE792136L (en) 1980-05-08
EP0011426B1 (en) 1983-06-22
CA1132584A (en) 1982-09-28
DK153947C (da) 1989-02-20
KR830001821B1 (ko) 1983-09-12
FI71139C (fi) 1986-11-24
DK471079A (da) 1980-05-09
AU5258279A (en) 1980-05-15
EP0011426A1 (en) 1980-05-28
AU513399B2 (en) 1980-11-27
IL58656A0 (en) 1980-02-29
DE2965755D1 (en) 1983-07-28
ES485798A1 (es) 1980-10-01
YU41675B (en) 1987-12-31
JPS56103176A (en) 1981-08-18
FI793487A7 (fi) 1980-05-09
KR830001273A (ko) 1983-04-30
DK153947B (da) 1988-09-26
PT70420A (de) 1979-12-01
JPS5585582A (en) 1980-06-27
AT366680B (de) 1982-04-26
IL58656A (en) 1983-06-15
FI71139B (fi) 1986-08-14
IE49109B1 (en) 1985-08-07
YU269779A (en) 1983-02-28

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