DE2965755D1 - Halogen-substituted benzopyran- and benzothiopyran-4-carboxylic acids, their preparation and pharmaceutical compositions containing the same - Google Patents

Halogen-substituted benzopyran- and benzothiopyran-4-carboxylic acids, their preparation and pharmaceutical compositions containing the same

Info

Publication number
DE2965755D1
DE2965755D1 DE7979302467T DE2965755T DE2965755D1 DE 2965755 D1 DE2965755 D1 DE 2965755D1 DE 7979302467 T DE7979302467 T DE 7979302467T DE 2965755 T DE2965755 T DE 2965755T DE 2965755 D1 DE2965755 D1 DE 2965755D1
Authority
DE
Germany
Prior art keywords
benzothiopyran
halogen
preparation
pharmaceutical compositions
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979302467T
Other languages
English (en)
Inventor
John L Belletire
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Pfizer Corp SRL
Original Assignee
Pfizer Corp Belgium
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium, Pfizer Corp SRL filed Critical Pfizer Corp Belgium
Application granted granted Critical
Publication of DE2965755D1 publication Critical patent/DE2965755D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE7979302467T 1978-11-08 1979-11-06 Halogen-substituted benzopyran- and benzothiopyran-4-carboxylic acids, their preparation and pharmaceutical compositions containing the same Expired DE2965755D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/959,023 US4210663A (en) 1978-11-08 1978-11-08 Halogen substituted benzopyran- and benzothiopyran-4-carboxylic acids

Publications (1)

Publication Number Publication Date
DE2965755D1 true DE2965755D1 (en) 1983-07-28

Family

ID=25501572

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7979302467T Expired DE2965755D1 (en) 1978-11-08 1979-11-06 Halogen-substituted benzopyran- and benzothiopyran-4-carboxylic acids, their preparation and pharmaceutical compositions containing the same

Country Status (16)

Country Link
US (1) US4210663A (de)
EP (1) EP0011426B1 (de)
JP (2) JPS6033433B2 (de)
KR (1) KR830001821B1 (de)
AR (1) AR223195A1 (de)
AT (1) AT366680B (de)
AU (1) AU513399B2 (de)
CA (1) CA1132584A (de)
DE (1) DE2965755D1 (de)
DK (1) DK153947C (de)
ES (1) ES485798A1 (de)
FI (1) FI71139C (de)
IE (1) IE49109B1 (de)
IL (1) IL58656A (de)
PT (1) PT70420A (de)
YU (1) YU41675B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4305955A (en) * 1980-10-21 1981-12-15 Pfizer Inc. Carboxylic acid therapeutic agents
US4486428A (en) * 1982-03-16 1984-12-04 Pfizer Inc. Bicyclic benzo fused compounds
US4537920A (en) * 1983-08-18 1985-08-27 Ethyl Corporation 4H-1-benzopyrans and lubricant compositions containing same
US4551542A (en) * 1984-09-26 1985-11-05 Pfizer Inc. Regeneration of 6-fluoro-4-chromanone from 6-fluoro-4-ureidochroman-4-carboxylic acid
WO1987004344A1 (en) * 1986-01-17 1987-07-30 Pfizer Inc. Hydroxyacetic acid derivatives for the treatment of diabetic complications
DE3737195A1 (de) * 1987-11-03 1989-05-18 Bayer Ag Chromanderivate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US5039672A (en) * 1990-04-05 1991-08-13 Pfizer Inc. Heterocyclic compounds as aldose reductase inhibitors
EP0541807B1 (de) * 1990-07-27 1997-12-17 Chugai Seiyaku Kabushiki Kaisha Benzopyranderivat
JP3255411B2 (ja) * 1991-02-18 2002-02-12 中外製薬株式会社 発毛促進剤
US5407897A (en) * 1993-03-03 1995-04-18 American Cyanamid Company Method for safening herbicides in crops using substituted benzopyran and tetrahydronaphthalene compounds
WO1999043315A1 (fr) * 1998-02-25 1999-09-02 Shionogi & Co., Ltd. Agent therapeutique utilisable en cas de complication de diabetes
US7288279B2 (en) * 2001-12-21 2007-10-30 Michael Foods Of Delaware, Inc. Formulated fried egg product
JP4742215B2 (ja) * 2003-06-23 2011-08-10 Ｊｎｃ株式会社 クロマン化合物、この化合物を含有する液晶組成物およびこの液晶組成物を含有する液晶表示素子
JP5956920B2 (ja) 2012-12-14 2016-07-27 株式会社コガネイ 液体供給装置

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications

Also Published As

Publication number Publication date
KR830001273A (ko) 1983-04-30
AR223195A1 (es) 1981-07-31
YU269779A (en) 1983-02-28
PT70420A (de) 1979-12-01
AU5258279A (en) 1980-05-15
JPS56103176A (en) 1981-08-18
FI793487A (fi) 1980-05-09
JPS6113716B2 (de) 1986-04-15
IE792136L (en) 1980-05-08
US4210663A (en) 1980-07-01
JPS5585582A (en) 1980-06-27
FI71139B (fi) 1986-08-14
IE49109B1 (en) 1985-08-07
JPS6033433B2 (ja) 1985-08-02
FI71139C (fi) 1986-11-24
KR830001821B1 (ko) 1983-09-12
EP0011426B1 (de) 1983-06-22
YU41675B (en) 1987-12-31
ES485798A1 (es) 1980-10-01
EP0011426A1 (de) 1980-05-28
AT366680B (de) 1982-04-26
IL58656A0 (en) 1980-02-29
DK471079A (da) 1980-05-09
DK153947B (da) 1988-09-26
ATA719279A (de) 1981-09-15
DK153947C (da) 1989-02-20
AU513399B2 (en) 1980-11-27
CA1132584A (en) 1982-09-28
IL58656A (en) 1983-06-15

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Legal Events

Date Code Title Description
8328 Change in the person/name/address of the agent

Free format text: LEDERER, F., DIPL.-CHEM. DR., PAT.-ANW., 8000 MUENCHEN

8339 Ceased/non-payment of the annual fee