JPS5981560A - 免疫定量方法およびその装置 - Google Patents

免疫定量方法およびその装置

Info

Publication number
JPS5981560A
JPS5981560A JP58154001A JP15400183A JPS5981560A JP S5981560 A JPS5981560 A JP S5981560A JP 58154001 A JP58154001 A JP 58154001A JP 15400183 A JP15400183 A JP 15400183A JP S5981560 A JPS5981560 A JP S5981560A
Authority
JP
Japan
Prior art keywords
fiber
antigen
capillary
complex
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58154001A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0521185B2 (fr
Inventor
ト−マス・ビ−・ハ−シユフエルド
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of JPS5981560A publication Critical patent/JPS5981560A/ja
Publication of JPH0521185B2 publication Critical patent/JPH0521185B2/ja
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Optics & Photonics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Plasma & Fusion (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP58154001A 1982-08-23 1983-08-23 免疫定量方法およびその装置 Granted JPS5981560A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US410340 1982-08-23
US06/410,340 US4447546A (en) 1982-08-23 1982-08-23 Fluorescent immunoassay employing optical fiber in capillary tube

Publications (2)

Publication Number Publication Date
JPS5981560A true JPS5981560A (ja) 1984-05-11
JPH0521185B2 JPH0521185B2 (fr) 1993-03-23

Family

ID=23624290

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58154001A Granted JPS5981560A (ja) 1982-08-23 1983-08-23 免疫定量方法およびその装置

Country Status (4)

Country Link
US (1) US4447546A (fr)
EP (1) EP0103426B1 (fr)
JP (1) JPS5981560A (fr)
DE (1) DE3380744D1 (fr)

Cited By (10)

* Cited by examiner, † Cited by third party
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JPS6177745A (ja) * 1984-09-17 1986-04-21 アー・フアウ・エル・アー・ゲー 試料中の物質濃度の蛍光測定装置
JPS6189528A (ja) * 1984-09-21 1986-05-07 コーニング　グラス　ワークス 分光分析測定に用いる導波管およびこれを用いた測定方法
JPS61191965A (ja) * 1984-12-10 1986-08-26 プルーテック　リミティド 液状分析物中の種のパラメ−タ−を光学的に確認する方法および装置
JPS61292044A (ja) * 1985-04-12 1986-12-22 ジーイーシー　―　マルコニ　リミテッド 光導波路バイオセンサ
JPS6280610A (ja) * 1985-09-09 1987-04-14 オルド，インコ−ポレ−テツド 光学装置
JPS62266464A (ja) * 1986-03-21 1987-11-19 マイロン　ジエ−．ブロツク 核酸分析
WO1990013029A1 (fr) * 1989-04-19 1990-11-01 Ibiden Co., Ltd. Reactif de dosage de substances biologiquement actives, son procede de production, procede et appareil de dosage
US5354574A (en) * 1992-06-23 1994-10-11 Ibiden Co., Ltd. Method for producing optical fiber having formyl groups on core surface thereof
US5401469A (en) * 1989-04-19 1995-03-28 Ibiden Co., Ltd. Plastic optical biomaterials assay device
US6010867A (en) * 1989-04-19 2000-01-04 Ibiden Co., Ltd. Reagent for biomaterials assay, preparation method thereof, and assay method

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EP0103426B1 (fr) 1989-10-18
EP0103426A3 (en) 1986-08-13
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US4447546A (en) 1984-05-08
JPH0521185B2 (fr) 1993-03-23
DE3380744D1 (en) 1989-11-23

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