JPS5980682A - 新規インドリジン誘導体、その製造法及び該誘導体を含有する医薬 - Google Patents

新規インドリジン誘導体、その製造法及び該誘導体を含有する医薬

Info

Publication number
JPS5980682A
JPS5980682A JP58110024A JP11002483A JPS5980682A JP S5980682 A JPS5980682 A JP S5980682A JP 58110024 A JP58110024 A JP 58110024A JP 11002483 A JP11002483 A JP 11002483A JP S5980682 A JPS5980682 A JP S5980682A
Authority
JP
Japan
Prior art keywords
indolizine
pharmacologically acceptable
acid addition
acceptable acid
addition salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58110024A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0372072B2 (cg-RX-API-DMAC7.html
Inventor
ジルベ−ル・ロツシ−ルズ
ピ−タ−・ポルスタ−
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of JPS5980682A publication Critical patent/JPS5980682A/ja
Publication of JPH0372072B2 publication Critical patent/JPH0372072B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • External Artificial Organs (AREA)
  • Telephonic Communication Services (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
JP58110024A 1982-06-17 1983-06-17 新規インドリジン誘導体、その製造法及び該誘導体を含有する医薬 Granted JPS5980682A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8210598 1982-06-17
FR8210598A FR2528845A1 (fr) 1982-06-17 1982-06-17 Nouveaux derives d'indolizine, leur procede de preparation ainsi que les compositions therapeutiques les contenant

Publications (2)

Publication Number Publication Date
JPS5980682A true JPS5980682A (ja) 1984-05-10
JPH0372072B2 JPH0372072B2 (cg-RX-API-DMAC7.html) 1991-11-15

Family

ID=9275110

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58110024A Granted JPS5980682A (ja) 1982-06-17 1983-06-17 新規インドリジン誘導体、その製造法及び該誘導体を含有する医薬

Country Status (25)

Country Link
US (1) US4499095A (cg-RX-API-DMAC7.html)
EP (1) EP0097636B1 (cg-RX-API-DMAC7.html)
JP (1) JPS5980682A (cg-RX-API-DMAC7.html)
KR (1) KR870001065B1 (cg-RX-API-DMAC7.html)
AT (1) ATE15042T1 (cg-RX-API-DMAC7.html)
AU (1) AU553758B2 (cg-RX-API-DMAC7.html)
BE (1) BE897059A (cg-RX-API-DMAC7.html)
CA (1) CA1195979A (cg-RX-API-DMAC7.html)
CS (1) CS240963B2 (cg-RX-API-DMAC7.html)
DD (1) DD210046A5 (cg-RX-API-DMAC7.html)
DE (1) DE3360609D1 (cg-RX-API-DMAC7.html)
DK (1) DK158000C (cg-RX-API-DMAC7.html)
ES (1) ES8403900A1 (cg-RX-API-DMAC7.html)
FI (1) FI74000C (cg-RX-API-DMAC7.html)
FR (1) FR2528845A1 (cg-RX-API-DMAC7.html)
GR (1) GR78285B (cg-RX-API-DMAC7.html)
HU (1) HU189298B (cg-RX-API-DMAC7.html)
IE (1) IE55429B1 (cg-RX-API-DMAC7.html)
IL (1) IL68778A (cg-RX-API-DMAC7.html)
NO (1) NO159723C (cg-RX-API-DMAC7.html)
NZ (1) NZ204608A (cg-RX-API-DMAC7.html)
PT (1) PT76876B (cg-RX-API-DMAC7.html)
SU (1) SU1194272A3 (cg-RX-API-DMAC7.html)
YU (1) YU43313B (cg-RX-API-DMAC7.html)
ZA (1) ZA833875B (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5215988A (en) * 1986-02-14 1993-06-01 Sanofi Aminoalkoxyphenyl derivatives, process of preparation and compositions containing the same
FR2642755B1 (cg-RX-API-DMAC7.html) * 1989-02-07 1993-11-05 Sanofi
FR2642756B1 (fr) * 1989-02-07 1994-03-04 Sanofi Derives cycloaminoalkoxyphenyle, leur procede de preparation ainsi que les compositions pharmaceutiques ou veterinaires en contenant
ES2114566T3 (es) * 1991-08-09 1998-06-01 Nycomed Innovation Ab Uso de radicales libres persistentes en formacion de imagenes por resonancia magnetica nuclear.
FR2838123B1 (fr) * 2002-04-04 2005-06-10 Sanofi Synthelabo Nouveaux derives d'indolozine-1,2,3 substituee, inhibiteurs selectifs du b-fgf
FR2859997B1 (fr) * 2003-09-18 2006-02-03 Sanofi Synthelabo Nouveaux derives d'indolizine 1,2,3,6,7,8 substituee, inhibiteurs des fgfs, leur procede de preparation et les compositions pharmaceutiques les contenant.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI61030C (fi) * 1976-02-19 1982-05-10 Sanofi Sa Foerfarande foer framstaellning av terapeutiskt verkande 2-substituerade-1- eller 3-benzoyl-indolizinderivat
US4378362A (en) * 1979-12-06 1983-03-29 S.A. Labaz N.V. Indolizine derivatives and process for preparing the same
FR2495616A1 (fr) * 1980-12-09 1982-06-11 Labaz Nv Nouveaux derives d'indolizine, leur procede de preparation ainsi que leurs applications en therapeutique

Also Published As

Publication number Publication date
BE897059A (fr) 1983-12-16
GR78285B (cg-RX-API-DMAC7.html) 1984-09-26
IE55429B1 (en) 1990-09-12
YU133183A (en) 1986-02-28
HU189298B (en) 1986-06-30
KR870001065B1 (ko) 1987-05-27
US4499095A (en) 1985-02-12
EP0097636B1 (fr) 1985-08-21
EP0097636A1 (fr) 1984-01-04
SU1194272A3 (ru) 1985-11-23
IL68778A0 (en) 1983-09-30
DK276183D0 (da) 1983-06-15
ES523389A0 (es) 1984-04-01
CS440183A2 (en) 1985-06-13
ZA833875B (en) 1984-02-29
DK158000C (da) 1990-08-20
IE831408L (en) 1983-12-17
FI832209L (fi) 1983-12-18
KR840005140A (ko) 1984-11-03
FR2528845B1 (cg-RX-API-DMAC7.html) 1984-11-23
NO159723B (no) 1988-10-24
FI74000B (fi) 1987-08-31
NZ204608A (en) 1985-09-13
IL68778A (en) 1986-10-31
CS240963B2 (en) 1986-03-13
FI74000C (fi) 1987-12-10
DK158000B (da) 1990-03-12
JPH0372072B2 (cg-RX-API-DMAC7.html) 1991-11-15
AU553758B2 (en) 1986-07-24
ES8403900A1 (es) 1984-04-01
CA1195979A (en) 1985-10-29
YU43313B (en) 1989-06-30
NO832176L (no) 1983-12-19
FR2528845A1 (fr) 1983-12-23
PT76876B (en) 1986-01-27
DE3360609D1 (en) 1985-09-26
NO159723C (no) 1989-02-01
DD210046A5 (de) 1984-05-30
ATE15042T1 (de) 1985-09-15
DK276183A (da) 1983-12-18
AU1542483A (en) 1984-12-20
PT76876A (en) 1983-07-01
FI832209A0 (fi) 1983-06-16

Similar Documents

Publication Publication Date Title
AU646006B2 (en) Diaza compounds
US4725691A (en) 2-[8-quinolinyl]-sulphinyl-1H-benzimidazole
RU2450813C2 (ru) Гипотензивная комбинация валсартана и блокатора кальциевых каналов
JPH0344377A (ja) 新規ピリミジン誘導体
JPH03133964A (ja) ピリミジン誘導体
US4374841A (en) Pyridoxine derivatives, and use in therapeutics
EA016079B1 (ru) Амидзамещенные индазолы в качестве ингибиторов поли(adp-рибоза)полимеразы (parp)
CS244148B2 (en) Method of aminomethylpyrrolidine production
TW200813012A (en) New indications for direct thrombin inhibitors
SK391292A3 (en) 4-alkyimidazole derivatives
FI79105B (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 1,4-dihydropyridinfoereningar.
EP0254327A2 (en) N-N-disubstituted-omega-(2-amino-3-(carbonylmethyl)-3,4-dihydroquinazolinyl) oxyalkylamides and related compounds
EP0485929A1 (de) Substituierte Azole, Verfahren zu ihrer Herstellung und ihre Verwendung
JPS5980682A (ja) 新規インドリジン誘導体、その製造法及び該誘導体を含有する医薬
JPH0655718B2 (ja) インダン誘導体および治療方法
JP4662979B2 (ja) 新規なβ−アゴニスト、その製造方法及びその薬物としての使用
US4616017A (en) Aminohydroxypropoxy substituted aryl compounds
US5155123A (en) Pyridine derivatives and pharmaceutical compositions containing them
KR870001795B1 (ko) 벤조푸란 유도체의 제조방법
HU189562B (en) Process for production of n-allil-5-chlor-n/4,5-dihydro-1/1-imidazol-2-il/-2,1-3-benzotiadiazol-4-amin
EP0725776B1 (en) 3-aryl-4-alkyl and 4,5-dialkyl-4h-1,2,4-triazoles useful as memory enhancers
WO2010095462A1 (ja) 新規な3-(5-アルコキシピリミジン-2-イル)ピリミジン-4(3h)-オン構造を有する化合物及びこれを含有する医薬
CZ20021332A3 (cs) Krystaly inhibitoru iontoměniče sodík-vodík typu 1
JP2003026677A (ja) 3−フェニル−3,7−ジアザビシクロ[3,3,1]ノナン−化合物、これを含有する医薬品、その使用及びその製法
JPH01104053A (ja) ドーパミン−β−ヒドロキシラーゼ抑製剤としての置換ピリジン類