JPS5929063B2 - 新規アリ−ルオキシアミノブタノ−ル誘導体の製法 - Google Patents

新規アリ−ルオキシアミノブタノ−ル誘導体の製法

Info

Publication number
JPS5929063B2
JPS5929063B2 JP50020452A JP2045275A JPS5929063B2 JP S5929063 B2 JPS5929063 B2 JP S5929063B2 JP 50020452 A JP50020452 A JP 50020452A JP 2045275 A JP2045275 A JP 2045275A JP S5929063 B2 JPS5929063 B2 JP S5929063B2
Authority
JP
Japan
Prior art keywords
general formula
compound
formula
phenyl
acid addition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP50020452A
Other languages
English (en)
Japanese (ja)
Other versions
JPS50117728A (pl
Inventor
ハルジヤ−ニ カ−ルマン
コルボニツツ デジエ−
モルナ−ル エルジエ−ベツト
セギ ヨ−ジエフ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KINOIN GIOGISUZERU ESU BEGIESUZECHI TERUKEMEKU GIARARUTO
Original Assignee
KINOIN GIOGISUZERU ESU BEGIESUZECHI TERUKEMEKU GIARARUTO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KINOIN GIOGISUZERU ESU BEGIESUZECHI TERUKEMEKU GIARARUTO filed Critical KINOIN GIOGISUZERU ESU BEGIESUZECHI TERUKEMEKU GIARARUTO
Publication of JPS50117728A publication Critical patent/JPS50117728A/ja
Publication of JPS5929063B2 publication Critical patent/JPS5929063B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/34—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/52—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
JP50020452A 1974-02-20 1975-02-20 新規アリ−ルオキシアミノブタノ−ル誘導体の製法 Expired JPS5929063B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUCI1449A HU169464B (pl) 1974-02-20 1974-02-20
HU001449 1974-02-20

Publications (2)

Publication Number Publication Date
JPS50117728A JPS50117728A (pl) 1975-09-16
JPS5929063B2 true JPS5929063B2 (ja) 1984-07-18

Family

ID=10994508

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50020452A Expired JPS5929063B2 (ja) 1974-02-20 1975-02-20 新規アリ−ルオキシアミノブタノ−ル誘導体の製法

Country Status (22)

Country Link
JP (1) JPS5929063B2 (pl)
AT (1) AT339281B (pl)
BE (1) BE825745A (pl)
BG (2) BG26366A3 (pl)
CA (1) CA1074338A (pl)
CH (1) CH619684A5 (pl)
CS (1) CS199578B2 (pl)
DD (1) DD119414A5 (pl)
DE (1) DE2506355C2 (pl)
DK (1) DK141935B (pl)
ES (2) ES434784A1 (pl)
FI (1) FI61304C (pl)
FR (1) FR2261001B1 (pl)
GB (1) GB1457086A (pl)
HU (1) HU169464B (pl)
IL (1) IL46634A (pl)
NL (1) NL182698C (pl)
NO (1) NO141754C (pl)
PL (2) PL99023B1 (pl)
SE (1) SE433935B (pl)
SU (1) SU1025327A3 (pl)
YU (2) YU36916B (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48309A (en) * 1974-10-25 1980-01-31 Robins Co Inc A H 1-aryloxy-4-amino-2-butanols and pharmaceutical compositions containing them
EP0097000B1 (en) * 1982-06-10 1987-09-09 Beecham Wuelfing GmbH & Co KG Amine derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA957364A (en) * 1968-11-18 1974-11-05 Pfizer Corporation Preparation of polar-substituted phenyl propanolamines
GB1245148A (en) * 1968-11-18 1971-09-08 Pfizer Ltd Propanolamine derivatives
SE384853B (sv) * 1972-04-04 1976-05-24 Haessle Ab Forfarande for framstellning av nya aminer
CH556818A (de) * 1969-09-24 1974-12-13 Ici Ltd Verfahren zur herstellung von alkanolaminderivaten.

Also Published As

Publication number Publication date
YU37375A (en) 1982-06-18
YU37116B (en) 1984-08-31
BE825745A (fr) 1975-06-16
BG26366A3 (pl) 1979-03-15
SE7501801L (pl) 1975-08-21
FI61304B (fi) 1982-03-31
GB1457086A (en) 1976-12-01
DK141935B (da) 1980-07-21
JPS50117728A (pl) 1975-09-16
AT339281B (de) 1977-10-10
BG26367A4 (pl) 1979-03-15
CS199578B2 (en) 1980-07-31
HU169464B (pl) 1976-11-28
YU36916B (en) 1984-08-31
CH619684A5 (en) 1980-10-15
FI61304C (fi) 1982-07-12
DE2506355C2 (de) 1983-10-06
DE2506355A1 (de) 1975-08-21
CA1074338A (en) 1980-03-25
NO141754C (no) 1980-05-07
DK141935C (pl) 1980-12-08
NL7501951A (nl) 1975-08-22
PL99023B1 (pl) 1978-06-30
SE433935B (sv) 1984-06-25
DK60875A (pl) 1975-10-20
ES434784A1 (es) 1977-03-16
PL99025B1 (pl) 1978-06-30
ES453326A1 (es) 1977-11-16
NO141754B (no) 1980-01-28
IL46634A (en) 1979-01-31
FI750443A (pl) 1975-08-21
NO750566L (pl) 1975-08-21
DD119414A5 (pl) 1976-04-20
YU167681A (en) 1983-04-27
FR2261001A1 (pl) 1975-09-12
SU1025327A3 (ru) 1983-06-23
IL46634A0 (en) 1975-04-25
ATA114075A (de) 1977-02-15
NL182698C (nl) 1988-05-02
FR2261001B1 (pl) 1978-07-21

Similar Documents

Publication Publication Date Title
US4234595A (en) 3-Indolyl-tertiary butylaminopropanols
KR950007753B1 (ko) 신규 인돌 유도체, 그 제조방법 및 그를 함유하는 의약 조성물
NO147950B (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive aminoalkyl-heterocykliske forbindelser
JP2637737B2 (ja) 新規な薬剤
DK153940B (da) Analogifremgangsmaade til fremstilling af 1-aryloxy-3-alkylamino-2-propanol-derivater eller farmaceutisk anvendelige, ugiftige syreadditionssalte deraf
JPH11512701A (ja) 選択的なβ▲下３▼アドレナリン作動性アゴニスト
JPS6136259A (ja) 新規オキシインドール‐誘導体、その製法及びこれを含有する心蔵及び循環系疾病の治療及び予防剤
US4001330A (en) Amino ethanol-indane and tetrahydronaphthalene derivatives
US4391821A (en) 7-Substituted benzopyranes and process for the preparation thereof
JP2001525399A (ja) 選択的β３アドレナリン作動性作動薬
US4314943A (en) Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols
JPH0251540B2 (pl)
US4363808A (en) N-(3-Phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines
EA005491B1 (ru) Способ получения циталопрама
JPS6340784B2 (pl)
JPH0285241A (ja) 気管支拡張活性を有する化合物
NO792113L (no) Membranstabiliserende forbindelser som har beta-receptor blokkerende aktivitet, deres fremgangsmaate samt fremgangsmaate for behandling av arrhytmetiske tilstander, og farmasoeytiske preparater som inneholder disse
JPS5929063B2 (ja) 新規アリ−ルオキシアミノブタノ−ル誘導体の製法
US3905990A (en) Basically substituted benzimidazole derivatives
JPS59144763A (ja) １−〔１−ベンズイミダゾリル〕−ｎ−〔２−（４−ヒドロキシ−３−メトキシフエニル）−２−ヒドロキシエチル〕−３−アミノブタン化合物、該化合物を含有する医薬、及び該化合物の製
US3984436A (en) Pyrrolyl compounds and processes for their manufacture
US4603019A (en) N-(methoxyphenacyl)-amine derivatives
IE59151B1 (en) New derivatives of 4-phenylpropyl indole and their salts, their preparation process, their use as medicaments and the pharmaceutical compositions containing them
US4495352A (en) Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols
JPS6024100B2 (ja) アミノプロパノ−ル−誘導体の製法