JPS59164724A - サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤 - Google Patents

サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤

Info

Publication number
JPS59164724A
JPS59164724A JP58038189A JP3818983A JPS59164724A JP S59164724 A JPS59164724 A JP S59164724A JP 58038189 A JP58038189 A JP 58038189A JP 3818983 A JP3818983 A JP 3818983A JP S59164724 A JPS59164724 A JP S59164724A
Authority
JP
Japan
Prior art keywords
surfactant
surface tension
phosphocholine
glycero
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58038189A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0378371B2 (https=
Inventor
Tsunetomo Takei
恒知 武井
Yousaku Kanazawa
金澤　洋作
Kazuo Masuda
増田　和夫
Yuji Tanaka
勇次 田中
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Tokyo Tanabe Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12518415&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPS59164724(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tokyo Tanabe Co Ltd filed Critical Tokyo Tanabe Co Ltd
Priority to JP58038189A priority Critical patent/JPS59164724A/ja
Priority to US06/583,866 priority patent/US4603124A/en
Priority to AU25125/84A priority patent/AU562676B2/en
Priority to EP84301513A priority patent/EP0119056B1/en
Priority to AT84301513T priority patent/ATE55908T1/de
Priority to GR74015A priority patent/GR81930B/el
Priority to DE8484301513T priority patent/DE3483055D1/de
Priority to IE553/84A priority patent/IE57006B1/en
Priority to CA000449223A priority patent/CA1208129A/en
Publication of JPS59164724A publication Critical patent/JPS59164724A/ja
Publication of JPH0378371B2 publication Critical patent/JPH0378371B2/ja
Priority to MX9203493A priority patent/MX9203493A/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0082—Lung surfactant, artificial mucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/395—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Otolaryngology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
JP58038189A 1983-03-10 1983-03-10 サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤 Granted JPS59164724A (ja)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP58038189A JPS59164724A (ja) 1983-03-10 1983-03-10 サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤
US06/583,866 US4603124A (en) 1983-03-10 1984-02-27 Surfactant and pharmaceutical compositions containing same
AU25125/84A AU562676B2 (en) 1983-03-10 1984-02-28 Surfactants having pulmonary surface activity
IE553/84A IE57006B1 (en) 1983-03-10 1984-03-07 Surfactant composition and pharmaceutical compositions containing same for use in the treatment of respiratory distress syndrome
AT84301513T ATE55908T1 (de) 1983-03-10 1984-03-07 Grenzflaechenaktives mittel und dieses enthaltende arzneimittel zur verwendung bei der behandlung des atemnotsyndroms.
EP84301513A EP0119056B1 (en) 1983-03-10 1984-03-07 Surfactant composition and pharmaceutical compositions containing same for use in the treatment of respiratory distress syndrome
GR74015A GR81930B (https=) 1983-03-10 1984-03-07
DE8484301513T DE3483055D1 (de) 1983-03-10 1984-03-07 Grenzflaechenaktives mittel und dieses enthaltende arzneimittel zur verwendung bei der behandlung des atemnotsyndroms.
CA000449223A CA1208129A (en) 1983-03-10 1984-03-09 Surfactant and pharmaceutical compositions containing same
MX9203493A MX9203493A (es) 1983-03-10 1992-06-26 Surfactantes y remedios para sindrome de tension respiratoria que contienen los mismos.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58038189A JPS59164724A (ja) 1983-03-10 1983-03-10 サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP62155390A Division JPS6361000A (ja) 1987-06-24 1987-06-24 リポ蛋白質及びその製造法

Publications (2)

Publication Number Publication Date
JPS59164724A true JPS59164724A (ja) 1984-09-17
JPH0378371B2 JPH0378371B2 (https=) 1991-12-13

Family

ID=12518415

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58038189A Granted JPS59164724A (ja) 1983-03-10 1983-03-10 サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤

Country Status (10)

Country Link
US (1) US4603124A (https=)
EP (1) EP0119056B1 (https=)
JP (1) JPS59164724A (https=)
AT (1) ATE55908T1 (https=)
AU (1) AU562676B2 (https=)
CA (1) CA1208129A (https=)
DE (1) DE3483055D1 (https=)
GR (1) GR81930B (https=)
IE (1) IE57006B1 (https=)
MX (1) MX9203493A (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994000131A1 (fr) * 1992-06-24 1994-01-06 Tokyo Tanabe Company Limited Agent prophylactique et agent curatif contre des maladies virales des voies respiratoires
JP2007500199A (ja) * 2003-05-30 2007-01-11 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ 合成界面活性剤のための新規な脂質混合物
JP2008520577A (ja) * 2004-11-15 2008-06-19 ディスカバリー ラボラトリーズ，インコーポレイテッド 肺表面活性物質配合物を凍結乾燥により生成する方法並びにその配合物及び利用
JP2015514714A (ja) * 2012-03-28 2015-05-21 ディスカバリー ラボラトリーズ，インコーポレイテッド 合成リポソーム肺サーファクタントの凍結乾燥

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5430020A (en) * 1984-12-11 1995-07-04 Scios Nova Inc. Recombinant alveolar surfactant protein
US5110806A (en) * 1985-06-26 1992-05-05 The Regents Of The University Of California Lung surfactant compositions
DE3528934A1 (de) * 1985-08-13 1987-02-26 Feldmuehle Ag Gleitelement aus keramischem werkstoff
WO1987002037A1 (en) * 1985-09-26 1987-04-09 Genetics Institute, Inc. Pulmonary surfactant proteins
US5256569A (en) * 1986-01-21 1993-10-26 Chisso Corporation Transesterification process for otereoselection of enantiomers of secondary alcohols using pseudomonas lipase with no added solvent
IT1203873B (it) * 1987-04-08 1989-02-23 Chiesi Farma Spa Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e
US4861756A (en) * 1988-03-08 1989-08-29 Merrell Dow Pharmaceuticals Inc. Synthetic pulmonary surfactant
DE3921954A1 (de) * 1989-07-04 1991-01-17 Thomae Gmbh Dr K Niedrig-viskose, hochkonzentrierte surfactant-suspension
US5174988A (en) * 1989-07-27 1992-12-29 Scientific Development & Research, Inc. Phospholipid delivery system
US5207220A (en) * 1989-12-12 1993-05-04 Burroughs Wellcome Co. Method for administering pharmaceuticals, including liquid surfactant, to the lungs
FR2658418B1 (fr) * 1990-02-20 1994-09-02 Synthelabo Compositions pharmaceutiques a base de phospholipides.
AU660612B2 (en) * 1990-05-18 1995-07-06 Mitsubishi-Tokyo Pharmaceuticals, Inc. Remedy for asthma
US5614216A (en) * 1990-10-17 1997-03-25 The Liposome Company, Inc. Synthetic lung surfactant
DE4418936A1 (de) * 1994-05-31 1996-02-08 Byk Gulden Lomberg Chem Fab Polypeptid
BR9506114A (pt) * 1994-12-29 1997-12-23 Ctro Nac Sanidad Agropecuaria Tensoativo pulmonar de origem suína e processo para a sua obtenção
US6129934A (en) * 1995-06-07 2000-10-10 Ony, Inc. Modification of animal lung surfactant for treating respiratory disease due to lung surfactant deficiency or dysfunction
UA59358C2 (uk) * 1996-01-24 2003-09-15 Бик Гулден Ломберг Хеміше Фабрік Гмбх Спосіб приготування порошкоподібного пульмонологічного порошкоподібного препарату та препарат, одержаний в такий спосіб
US6172203B1 (en) * 1996-02-07 2001-01-09 Alfredo Adolfo Hager Method for extracting and purifying pulmonary surfactant
WO1997035882A1 (en) * 1996-03-27 1997-10-02 Ortho Pharmaceutical Corporation Lyophilized pulmonary surfactant peptide compositions
US5667948A (en) * 1996-04-16 1997-09-16 Eastman Kodak Company Processing silver halide films with an aqueous phospholipid rinse solution
ES2191355T3 (es) * 1997-12-24 2003-09-01 Britannia Pharmaceuticals Ltd Uso de un tensioactivo para la preparacion de un medicamento para el tratamiento de trastornos del oido medio.
US7053176B1 (en) 1999-09-16 2006-05-30 Altana Pharma Ag Combination of C1-INH and lung surfactant for the treatment of respiratory disorders
DE10018022A1 (de) * 2000-04-12 2001-10-31 Byk Gulden Lomberg Chem Fab Neue Verwendung von Lungensurfactant zur Prophylaxe oder Frühbehandlung von akuten Lungenerkrankungen
GB0026239D0 (en) * 2000-10-26 2000-12-13 Britannia Pharmaceuticals Ltd Surface active lipids in treatment of wet lung
WO2003006989A1 (fr) * 2001-07-12 2003-01-23 Kyowa Medex Co., Ltd. Procede de quantification de lipoproteines denaturees, reactifs pour la quantification de lipoproteines denaturees, procede de detection de maladies du systeme circulatoire et reactifs pour la detection de maladies du systeme circulatoire
ES2346048T3 (es) 2001-10-11 2010-10-08 Nycomed Gmbh Nueva utilizacion de un agente tensioactivo pulmonar.
CA2575513C (en) 2004-08-06 2014-09-16 Altana Pharma Ag Composition comprising a pulmonary surfactant and a tnf-derived peptide
US8337815B2 (en) * 2004-12-23 2012-12-25 Discovery Laboratories, Inc. Pulmonary surfactant formulations
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
WO2010068754A2 (en) 2008-12-10 2010-06-17 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of medicaments to the lungs
CN103052380B (zh) 2010-08-23 2015-11-25 塔科达有限责任公司 包含治疗活性物质的湿润颗粒

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE388023C (de) * 1922-02-14 1924-01-07 Chem Fab Verfahren zur Herstellung von waesserigen Lezithinemulsionen
FR2343481A1 (fr) * 1976-03-11 1977-10-07 Gerlich Norbert Composition destinee a empecher les lesions des membranes biologiques et a regenerer ces membranes une fois qu'elles ont ete endommagees
DE2900300A1 (de) * 1979-01-05 1980-07-17 Lebrecht Von Dr Klitzing Verfahren einer prophylaxe zur vermeidung des atemnotsyndroms bei fruehgeborenen und bei der schocklunge
JPS55160721A (en) * 1979-06-02 1980-12-13 Tokyo Tanabe Co Ltd Pulmonary surfactant ta-546, its preparation, and remedy for pulmonary hyaline membrane syndrome comprising it as active constituent
US4312860A (en) * 1980-10-24 1982-01-26 Regents Of The University Of California Lung surfactant compositions
JPS5845299A (ja) * 1981-09-10 1983-03-16 東京田辺製薬株式会社 新規な表面活性物質、その製造法及びそれを含有する呼吸窮迫疾候群治療剤

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994000131A1 (fr) * 1992-06-24 1994-01-06 Tokyo Tanabe Company Limited Agent prophylactique et agent curatif contre des maladies virales des voies respiratoires
JP2007500199A (ja) * 2003-05-30 2007-01-11 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ 合成界面活性剤のための新規な脂質混合物
JP4767854B2 (ja) * 2003-05-30 2011-09-07 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ 合成界面活性剤のための新規な脂質混合物
JP2008520577A (ja) * 2004-11-15 2008-06-19 ディスカバリー ラボラトリーズ，インコーポレイテッド 肺表面活性物質配合物を凍結乾燥により生成する方法並びにその配合物及び利用
JP2015514714A (ja) * 2012-03-28 2015-05-21 ディスカバリー ラボラトリーズ，インコーポレイテッド 合成リポソーム肺サーファクタントの凍結乾燥

Also Published As

Publication number Publication date
EP0119056A2 (en) 1984-09-19
DE3483055D1 (de) 1990-10-04
EP0119056A3 (en) 1986-06-25
AU562676B2 (en) 1987-06-18
JPH0378371B2 (https=) 1991-12-13
CA1208129A (en) 1986-07-22
US4603124A (en) 1986-07-29
IE840553L (en) 1984-09-10
IE57006B1 (en) 1992-03-11
AU2512584A (en) 1984-09-13
EP0119056B1 (en) 1990-08-29
ATE55908T1 (de) 1990-09-15
MX9203493A (es) 1992-08-01
GR81930B (https=) 1984-12-12

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