JPS5824558A - ピロリジン誘導体 - Google Patents

ピロリジン誘導体

Info

Publication number
JPS5824558A
JPS5824558A JP57127795A JP12779582A JPS5824558A JP S5824558 A JPS5824558 A JP S5824558A JP 57127795 A JP57127795 A JP 57127795A JP 12779582 A JP12779582 A JP 12779582A JP S5824558 A JPS5824558 A JP S5824558A
Authority
JP
Japan
Prior art keywords
ethyl
compound
acetamide
compound according
represents hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57127795A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0345064B2 (enExample
Inventor
ベルナ−・アツシユバンデン
エミリオ・キブルツ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JPS5824558A publication Critical patent/JPS5824558A/ja
Publication of JPH0345064B2 publication Critical patent/JPH0345064B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
JP57127795A 1981-07-24 1982-07-23 ピロリジン誘導体 Granted JPS5824558A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH4849/81A CH647234A5 (en) 1981-07-24 1981-07-24 Pyrrolidine derivatives
CH4849/81-6 1981-07-24
CH2768/82-3 1982-05-05

Publications (2)

Publication Number Publication Date
JPS5824558A true JPS5824558A (ja) 1983-02-14
JPH0345064B2 JPH0345064B2 (enExample) 1991-07-09

Family

ID=4283624

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57127795A Granted JPS5824558A (ja) 1981-07-24 1982-07-23 ピロリジン誘導体

Country Status (10)

Country Link
JP (1) JPS5824558A (enExample)
KR (1) KR890000768B1 (enExample)
BR (1) BR8204328A (enExample)
CH (1) CH647234A5 (enExample)
ES (1) ES8404678A1 (enExample)
GR (1) GR76177B (enExample)
IS (1) IS2742A7 (enExample)
MW (1) MW2682A1 (enExample)
PL (1) PL138918B1 (enExample)
ZA (1) ZA825104B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH666891A5 (de) * 1985-11-26 1988-08-31 Lonza Ag 4-alkoxy-2-oxo-pyrrolidin-1-yl-essigsaeure-c(1)-c(4)-alkylester, deren herstellung und verwendung.
KR100498268B1 (ko) * 1997-12-09 2005-11-01 주식회사 엘지생활건강 피롤리돈계 양쪽성 계면활성제

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS562960A (en) * 1979-06-13 1981-01-13 Nattermann A & Cie Pyrrolidinylalkylcarboxylic acid amide derivative* its manufacture and medicinal composition

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS562960A (en) * 1979-06-13 1981-01-13 Nattermann A & Cie Pyrrolidinylalkylcarboxylic acid amide derivative* its manufacture and medicinal composition

Also Published As

Publication number Publication date
IS2742A7 (is) 1983-01-25
KR840000489A (ko) 1984-02-22
KR890000768B1 (ko) 1989-04-05
PL237634A1 (en) 1984-01-30
ZA825104B (en) 1983-04-27
PL138918B1 (en) 1986-11-29
BR8204328A (pt) 1983-07-19
ES520820A0 (es) 1984-05-16
MW2682A1 (en) 1984-03-14
GR76177B (enExample) 1984-08-03
ES8404678A1 (es) 1984-05-16
CH647234A5 (en) 1985-01-15
JPH0345064B2 (enExample) 1991-07-09

Similar Documents

Publication Publication Date Title
KR101398264B1 (ko) Ｐ２ｘ７­수용체 길항제로서의 치환된 ｎ­페닐메틸­５­옥소­프롤린­２­아미드 및 그의 사용 방법
AU664188B2 (en) Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
DE3884563T2 (de) Aminomethyl-oxo-oxazolidinyl-ethenylbenzen-Derivate, nützlich als antibakterielles Mittel.
KR100194162B1 (ko) 다관능성 약학적 화합물
DE68927875T2 (de) N-substituierte azaheterocyclische Carbonsäuren
DE69411260T2 (de) Thiazolidinederivate ihre herstellung und sie enthaltende medikamente
CN103012378A (zh) 作为5-ht2a血清素受体调节剂适用于治疗与其相关的病症的3-苯基-吡唑衍生物
US4517183A (en) N-Substituted aziridine-2-carboxylic acid derivatives
HU187777B (en) Process for preparing pyrrolidine derivatives
JPH06505238A (ja) ３−ピペリジニルメチルカルボキシレート置換インドール
JPS6322074A (ja) ４−アミノ−キノリン−３−カルボキサミド、その製造法および該化合物を含有する製薬学的組成物
EP0003056A1 (de) N-substituierte omega-Aminoalkanoyl-omega-aminoalkansäuren, ihre Verwendung und Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
WO2004091605A1 (ja) アルキルエーテル誘導体またはその塩を含有する網膜神経疾患の予防・治療剤
JPH0372467A (ja) ピペラジン誘導体
LU83096A1 (de) Cyclohexen-derivate
JPH06508348A (ja) テトラヒドロチエノ（２，３−ｃ）ピリジン誘導体、その製造方法およびその医薬用途
HRP931025A2 (en) Amino acid derivatives
JPS6230762A (ja) 新規５−オキソ−１−イミダゾリジンアセトアミド誘導体
JPS5824558A (ja) ピロリジン誘導体
JPH08503229A (ja) Ｇａｂａ−ｂアンタゴニストとしての２−置換モルホリンおよびチオモルホリン誘導体
JPS62461A (ja) ピロリドン誘導体及びその製造方法
DE69529790T2 (de) Imidazolin-Derivate, deren Herstellung und deren Verwendung als Tachykinin-Rezeptor Antagonisten
JPH07503478A (ja) 新規なインドリノン誘導体，その製造及びこのものを含む製薬学的組成物
DE3888811T2 (de) Tricyclische Carbamate, Verfahren zu ihrer Herstellung und ihre therapeutische Verwendung.
US4661592A (en) 4H-pyrimido[2,1-a]isoquinolin-4-one derivatives