KR890000768B1 - 피롤리딘 유도체 및 이의 제조방법 - Google Patents

피롤리딘 유도체 및 이의 제조방법 Download PDF

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Publication number
KR890000768B1
KR890000768B1 KR8203307A KR820003307A KR890000768B1 KR 890000768 B1 KR890000768 B1 KR 890000768B1 KR 8203307 A KR8203307 A KR 8203307A KR 820003307 A KR820003307 A KR 820003307A KR 890000768 B1 KR890000768 B1 KR 890000768B1
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KR
South Korea
Prior art keywords
oxo
pyrrolidinyl
hydrogen
formula
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR8203307A
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English (en)
Korean (ko)
Other versions
KR840000489A (ko
Inventor
아쉬반덴 베네르
키부르츠 에밀리오
Original Assignee
버나드 에스.레온
호프만-라 롯슈 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 버나드 에스.레온, 호프만-라 롯슈 인코포레이티드 filed Critical 버나드 에스.레온
Publication of KR840000489A publication Critical patent/KR840000489A/ko
Priority to KR1019890000280A priority Critical patent/KR890000767B1/ko
Application granted granted Critical
Publication of KR890000768B1 publication Critical patent/KR890000768B1/ko
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
KR8203307A 1981-07-24 1982-07-23 피롤리딘 유도체 및 이의 제조방법 Expired KR890000768B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019890000280A KR890000767B1 (ko) 1981-07-24 1989-01-12 피롤리딘 유도체의 제조방법

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH4849/81 1981-07-24
CH4849/81A CH647234A5 (en) 1981-07-24 1981-07-24 Pyrrolidine derivatives

Publications (2)

Publication Number Publication Date
KR840000489A KR840000489A (ko) 1984-02-22
KR890000768B1 true KR890000768B1 (ko) 1989-04-05

Family

ID=4283624

Family Applications (1)

Application Number Title Priority Date Filing Date
KR8203307A Expired KR890000768B1 (ko) 1981-07-24 1982-07-23 피롤리딘 유도체 및 이의 제조방법

Country Status (10)

Country Link
JP (1) JPS5824558A (enExample)
KR (1) KR890000768B1 (enExample)
BR (1) BR8204328A (enExample)
CH (1) CH647234A5 (enExample)
ES (1) ES8404678A1 (enExample)
GR (1) GR76177B (enExample)
IS (1) IS2742A7 (enExample)
MW (1) MW2682A1 (enExample)
PL (1) PL138918B1 (enExample)
ZA (1) ZA825104B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH666891A5 (de) * 1985-11-26 1988-08-31 Lonza Ag 4-alkoxy-2-oxo-pyrrolidin-1-yl-essigsaeure-c(1)-c(4)-alkylester, deren herstellung und verwendung.
KR100498268B1 (ko) * 1997-12-09 2005-11-01 주식회사 엘지생활건강 피롤리돈계 양쪽성 계면활성제

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2923975A1 (de) * 1979-06-13 1980-12-18 Nattermann A & Cie Pyrrolidinone, verfahren zu deren herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
IS2742A7 (is) 1983-01-25
KR840000489A (ko) 1984-02-22
JPS5824558A (ja) 1983-02-14
PL237634A1 (en) 1984-01-30
ZA825104B (en) 1983-04-27
PL138918B1 (en) 1986-11-29
BR8204328A (pt) 1983-07-19
ES520820A0 (es) 1984-05-16
MW2682A1 (en) 1984-03-14
GR76177B (enExample) 1984-08-03
ES8404678A1 (es) 1984-05-16
CH647234A5 (en) 1985-01-15
JPH0345064B2 (enExample) 1991-07-09

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US4452807A (en) (R,S)-1-(3-Hydroxy-4-methoxybenzoyl)-3-hydroxy-2-pyrrolidinone intermediates therefor and use for treating cerebral insufficiency
KR890000768B1 (ko) 피롤리딘 유도체 및 이의 제조방법
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