JPS58126789A - レースレオニンの製造法 - Google Patents

レースレオニンの製造法

Info

Publication number
JPS58126789A
JPS58126789A JP56211908A JP21190881A JPS58126789A JP S58126789 A JPS58126789 A JP S58126789A JP 56211908 A JP56211908 A JP 56211908A JP 21190881 A JP21190881 A JP 21190881A JP S58126789 A JPS58126789 A JP S58126789A
Authority
JP
Japan
Prior art keywords
gene
strain
dna
corynebacterium
medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56211908A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0138475B2 (enExample
Inventor
Ryoichi Katsumata
勝亦　瞭一
Akio Ozaki
尾崎　明夫
Toru Mizukami
水上　透
Motoko Kageyama
影山　基子
Morimasa Yagisawa
八木澤　守正
Tamio Mizukami
民夫 水上
Seiga Itou
伊藤　菁莪
Tetsuo Oka
岡　徹夫
Akira Furuya
古屋　晃
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=16613637&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPS58126789(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to JP56211908A priority Critical patent/JPS58126789A/ja
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to AT82112072T priority patent/ATE41677T1/de
Priority to DE198282112072T priority patent/DE88166T1/de
Priority to EP82112072A priority patent/EP0088166B2/en
Priority to DE8282112072T priority patent/DE3279568D1/de
Priority to ES518665A priority patent/ES8404409A1/es
Priority to CA000418680A priority patent/CA1202257A/en
Priority to AU91919/82A priority patent/AU557228B2/en
Priority to IL8857083A priority patent/IL88570A/xx
Priority to MX026823A priority patent/MX174306B/es
Priority to IL67614A priority patent/IL67614A/xx
Publication of JPS58126789A publication Critical patent/JPS58126789A/ja
Priority to IL88570A priority patent/IL88570A0/xx
Publication of JPH0138475B2 publication Critical patent/JPH0138475B2/ja
Priority to US07/474,648 priority patent/US5236831A/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP56211908A 1981-12-29 1981-12-29 レースレオニンの製造法 Granted JPS58126789A (ja)

Priority Applications (13)

Application Number Priority Date Filing Date Title
JP56211908A JPS58126789A (ja) 1981-12-29 1981-12-29 レースレオニンの製造法
AT82112072T ATE41677T1 (de) 1981-12-29 1982-12-28 Verfahren zum exprimieren eines gens.
DE198282112072T DE88166T1 (de) 1981-12-29 1982-12-28 Verfahren zum exprimieren eines gens.
EP82112072A EP0088166B2 (en) 1981-12-29 1982-12-28 Method for expressing a gene
DE8282112072T DE3279568D1 (en) 1981-12-29 1982-12-28 Method for expressing a gene
ES518665A ES8404409A1 (es) 1981-12-29 1982-12-29 Un metodo de expresion de un gen.
CA000418680A CA1202257A (en) 1981-12-29 1982-12-29 Method for expressing a gene
AU91919/82A AU557228B2 (en) 1981-12-29 1982-12-30 Method for expressing a gene
IL67614A IL67614A (en) 1981-12-29 1983-01-03 Process for producing l-threonine or l-glutamic acid by corynebacterium and brevibacterium
IL8857083A IL88570A (en) 1981-12-29 1983-01-03 Process for producing l-lysine by corynebacterium and brevibacterium
MX026823A MX174306B (es) 1981-12-29 1983-01-03 Un proceso para producir un producto metabolico
IL88570A IL88570A0 (en) 1981-12-29 1988-12-02 Process for producing l-lysine
US07/474,648 US5236831A (en) 1981-12-29 1990-02-02 Amino acid synthesis in corynebacteria using E. coli genes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56211908A JPS58126789A (ja) 1981-12-29 1981-12-29 レースレオニンの製造法

Related Child Applications (4)

Application Number Title Priority Date Filing Date
JP32995888A Division JPH02472A (ja) 1988-12-26 1988-12-26 Ｌ―グルタミン酸の製造方法
JP32996088A Division JPH02471A (ja) 1988-12-26 1988-12-26 Ｌ―リジンの製造法
JP32996188A Division JPH02473A (ja) 1988-12-26 1988-12-26 Ｌ―トリプトファンの製造法
JP32995988A Division JPH02474A (ja) 1988-12-26 1988-12-26 Ｌ―ヒスチジンの製造法

Publications (2)

Publication Number Publication Date
JPS58126789A true JPS58126789A (ja) 1983-07-28
JPH0138475B2 JPH0138475B2 (enExample) 1989-08-14

Family

ID=16613637

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56211908A Granted JPS58126789A (ja) 1981-12-29 1981-12-29 レースレオニンの製造法

Country Status (9)

Country Link
EP (1) EP0088166B2 (enExample)
JP (1) JPS58126789A (enExample)
AT (1) ATE41677T1 (enExample)
AU (1) AU557228B2 (enExample)
CA (1) CA1202257A (enExample)
DE (2) DE88166T1 (enExample)
ES (1) ES8404409A1 (enExample)
IL (1) IL67614A (enExample)
MX (1) MX174306B (enExample)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59156294A (ja) * 1983-02-17 1984-09-05 Kyowa Hakko Kogyo Co Ltd ヒスチジンの製造法
JPS6062983A (ja) * 1983-09-14 1985-04-11 Ajinomoto Co Inc 発酵法によるｌ―ヒスチジンの製造法
JPS60210994A (ja) * 1984-04-06 1985-10-23 Kyowa Hakko Kogyo Co Ltd ヒスチジンの製造法
JPS6140797A (ja) * 1984-07-31 1986-02-27 Ajinomoto Co Inc Ｌ−トリプトフアンの製造法
JPS6188889A (ja) * 1984-10-04 1986-05-07 Ajinomoto Co Inc 発酵法によるｌ−アミノ酸の製造法
JPS6236196A (ja) * 1985-04-15 1987-02-17 Ajinomoto Co Inc アラニンの製造法
JPS6279788A (ja) * 1985-10-04 1987-04-13 Kyowa Hakko Kogyo Co Ltd アミノ酸の製造法
US7368266B2 (en) 2001-02-13 2008-05-06 Cj Corporation Method for L-threonine production

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0691827B2 (ja) * 1981-12-17 1994-11-16 協和醗酵工業株式会社 新規ベクタ−プラスミド
JPH0732710B2 (ja) * 1983-05-28 1995-04-12 協和醗酵工業株式会社 フエニ−ルアラニンの製造法
JPS59156292A (ja) * 1983-02-17 1984-09-05 Kyowa Hakko Kogyo Co Ltd トリプトフアンの製造法
DE3484378D1 (de) * 1983-02-17 1991-05-08 Kyowa Hakko Kogyo Kk Herstellungsverfahren fuer l-histidin.
JPS6066989A (ja) * 1983-09-24 1985-04-17 Kyowa Hakko Kogyo Co Ltd Ｌ−アルギニンの製造法
JPH0783714B2 (ja) * 1983-08-29 1995-09-13 味の素株式会社 発酵法によるｌ―アミノ酸の製造法
JPS6062982A (ja) * 1983-09-14 1985-04-11 Ajinomoto Co Inc 組換えｄνａ，該組換えｄνａを有する細菌及び該細菌を用いるｌ−スレオニン又はｌ−イソロイシンの製造法
JPS6066984A (ja) * 1983-09-22 1985-04-17 Ajinomoto Co Inc 発酵法によるｌ−フェニルアラニンの製造法
CA1277931C (en) * 1984-06-05 1990-12-18 Shimon Ulitzur Detection and/or identification of microorganisms in a test sample usingbioluminescence or other exogenous genetically-introduced marker
GB2165546B (en) * 1984-08-21 1989-05-17 Asahi Chemical Ind A plasmid containing a gene for tetracycline resistance and dna fragments derived therefrom
JPH0655149B2 (ja) * 1985-03-12 1994-07-27 協和醗酵工業株式会社 Ｌ―リジンの製造法
FR2581653B1 (fr) * 1985-05-10 1989-06-30 Asahi Chemical Ind Fragment d'adn contenant un gene codant pour la phosphoenolpyruvate carboxylase, adn recombinant le contenant et micro-organisme contenant ce dernier
DE204326T1 (de) * 1985-06-05 1987-07-02 Kyowa Hakko Kogyo Co., Ltd., Tokio/Tokyo Verfahren zur herstellung von l-threonin und l-isoleucin.
FR2590592B1 (fr) * 1985-11-26 1989-12-22 Asahi Chemical Ind Fragment d'adn contenant un gene codant pour une enzyme catalysant une reaction dans le cycle tca et adn recombinant le contenant.
US4920054A (en) * 1986-07-25 1990-04-24 Allelix, Inc. Shuttle vectors from rhodococcus equi
JPS63273469A (ja) * 1986-12-13 1988-11-10 Kyowa Hakko Kogyo Co Ltd 乳糖資化性を有する新規微生物
WO1988009819A2 (en) * 1987-06-12 1988-12-15 Massachusetts Institute Of Technology C. glutamicum threonine biosynthetic pathway
US6649379B1 (en) 1987-06-12 2003-11-18 Massachusetts Institute Of Technology Method and deregulated enzyme for threonine production
DE3888076T2 (de) * 1987-10-15 1994-07-14 Mitsubishi Petrochemical Co Verfahren zur Herstellung von L-Threonin.
DE3908201A1 (de) * 1989-03-14 1990-09-27 Degussa Verfahren zur fermentativen herstellung von l-lysin
FR2747131B1 (fr) * 1996-04-09 1998-06-26 Orsan Procede de production d'amino acide par fermentation de corynebacterie exprimant une activite trehalase
DE19912384A1 (de) * 1999-03-19 2000-09-21 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
DE19924364A1 (de) * 1999-05-27 2000-11-30 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
US6586214B1 (en) 1999-09-15 2003-07-01 Degussa Ag Method for increasing the metabolic flux through the pentose phosphate cycle in coryneform bacteria by regulation of the phosphoglucose isomerase (pgi gene)
RU2416636C2 (ru) 2004-12-06 2011-04-20 Сейдж Байосайенсиз Инк. Способ выращивания продуцирующей лизин грамположительной бактерии для доставки биологически активных соединений жвачным животным, кормовая добавка (варианты) и способ кормления жвачных животных

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56148295A (en) * 1980-04-17 1981-11-17 Ajinomoto Co Inc Preparation of l-glutamic acid by fermentation method
JPS56148296A (en) * 1980-04-17 1981-11-17 Ajinomoto Co Inc Preparation of l-glutamic acid by fermentation method
JPS56160997A (en) * 1980-05-16 1981-12-11 Ajinomoto Co Inc Preparation of l-lysine by fermenaition method
JPS57186496A (en) * 1981-05-11 1982-11-16 Ajinomoto Co Inc Preparation of l-threonine by fermentation
JPS58893A (ja) * 1981-06-25 1983-01-06 Ajinomoto Co Inc 発酵法によるｌ−イソロイシンの製造法
JPS5867699A (ja) * 1981-10-16 1983-04-22 Ajinomoto Co Inc プラスミド

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2076853B (en) * 1980-04-17 1983-12-21 Ajinomoto Kk L-glutamic acid producing microorganisms
JPS57134500A (en) * 1981-02-12 1982-08-19 Kyowa Hakko Kogyo Co Ltd Plasmid pcg1
JPS57183799A (en) * 1981-04-17 1982-11-12 Kyowa Hakko Kogyo Co Ltd Novel plasmid
JPS5835197A (ja) * 1981-08-26 1983-03-01 Kyowa Hakko Kogyo Co Ltd プラスミドｐｃｇ２
JPH0691827B2 (ja) * 1981-12-17 1994-11-16 協和醗酵工業株式会社 新規ベクタ−プラスミド
ES522029A0 (es) * 1982-05-04 1984-07-16 Ajinomoto Kk Procedimiento para preparar un plasmido compuesto.

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56148295A (en) * 1980-04-17 1981-11-17 Ajinomoto Co Inc Preparation of l-glutamic acid by fermentation method
JPS56148296A (en) * 1980-04-17 1981-11-17 Ajinomoto Co Inc Preparation of l-glutamic acid by fermentation method
JPS56160997A (en) * 1980-05-16 1981-12-11 Ajinomoto Co Inc Preparation of l-lysine by fermenaition method
JPS57186496A (en) * 1981-05-11 1982-11-16 Ajinomoto Co Inc Preparation of l-threonine by fermentation
JPS58893A (ja) * 1981-06-25 1983-01-06 Ajinomoto Co Inc 発酵法によるｌ−イソロイシンの製造法
JPS5867699A (ja) * 1981-10-16 1983-04-22 Ajinomoto Co Inc プラスミド

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59156294A (ja) * 1983-02-17 1984-09-05 Kyowa Hakko Kogyo Co Ltd ヒスチジンの製造法
JPS6062983A (ja) * 1983-09-14 1985-04-11 Ajinomoto Co Inc 発酵法によるｌ―ヒスチジンの製造法
JPS60210994A (ja) * 1984-04-06 1985-10-23 Kyowa Hakko Kogyo Co Ltd ヒスチジンの製造法
JPS6140797A (ja) * 1984-07-31 1986-02-27 Ajinomoto Co Inc Ｌ−トリプトフアンの製造法
JPS6188889A (ja) * 1984-10-04 1986-05-07 Ajinomoto Co Inc 発酵法によるｌ−アミノ酸の製造法
JPS6236196A (ja) * 1985-04-15 1987-02-17 Ajinomoto Co Inc アラニンの製造法
JPS6279788A (ja) * 1985-10-04 1987-04-13 Kyowa Hakko Kogyo Co Ltd アミノ酸の製造法
US7368266B2 (en) 2001-02-13 2008-05-06 Cj Corporation Method for L-threonine production

Also Published As

Publication number Publication date
IL67614A (en) 1990-11-29
EP0088166A3 (en) 1984-04-25
EP0088166B1 (en) 1989-03-22
DE88166T1 (de) 1984-03-15
ES518665A0 (es) 1984-04-16
EP0088166B2 (en) 1997-06-25
CA1202257A (en) 1986-03-25
AU557228B2 (en) 1986-12-11
ATE41677T1 (de) 1989-04-15
EP0088166A2 (en) 1983-09-14
IL67614A0 (en) 1983-05-15
JPH0138475B2 (enExample) 1989-08-14
AU9191982A (en) 1983-07-07
MX174306B (es) 1994-05-04
ES8404409A1 (es) 1984-04-16
DE3279568D1 (en) 1989-04-27

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