JPS572240A - Ml-236b derivative - Google Patents

Ml-236b derivative

Info

Publication number
JPS572240A
JPS572240A JP7612780A JP7612780A JPS572240A JP S572240 A JPS572240 A JP S572240A JP 7612780 A JP7612780 A JP 7612780A JP 7612780 A JP7612780 A JP 7612780A JP S572240 A JPS572240 A JP S572240A
Authority
JP
Japan
Prior art keywords
dum
urine
acetone
residue
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7612780A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6113699B2 (enExample
Inventor
Minoru Tanaka
Akira Terahara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP7612780A priority Critical patent/JPS572240A/ja
Priority to DK247081A priority patent/DK149080C/da
Priority to MX819478U priority patent/MX7065E/es
Priority to KR1019810002023A priority patent/KR840001055B1/ko
Priority to CH3722/81A priority patent/CH655090A5/de
Priority to FR8111190A priority patent/FR2483912B1/fr
Priority to FI811762A priority patent/FI71168C/fi
Priority to NL8102737A priority patent/NL191738C/xx
Priority to IT67777/81A priority patent/IT1144598B/it
Priority to AU71376/81A priority patent/AU549988B2/en
Priority to SE8103560A priority patent/SE453389B/sv
Priority to ES502827A priority patent/ES502827A0/es
Priority to DE19813122499 priority patent/DE3122499A1/de
Priority to IE1257/81A priority patent/IE51270B1/en
Priority to US06/270,846 priority patent/US4346227A/en
Priority to GB8117450A priority patent/GB2077264B/en
Priority to CA000379232A priority patent/CA1150170A/en
Priority to BE0/205046A priority patent/BE889150A/fr
Priority to AT0256781A priority patent/AT374495B/de
Publication of JPS572240A publication Critical patent/JPS572240A/ja
Priority to US06/351,974 priority patent/US4410629A/en
Priority to US06/351,975 priority patent/US4448979A/en
Publication of JPS6113699B2 publication Critical patent/JPS6113699B2/ja
Priority to MX9203563A priority patent/MX9203563A/es
Priority to NL960028C priority patent/NL960028I2/nl
Granted legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP7612780A 1980-06-06 1980-06-06 Ml-236b derivative Granted JPS572240A (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
JP7612780A JPS572240A (en) 1980-06-06 1980-06-06 Ml-236b derivative
DK247081A DK149080C (da) 1980-06-06 1981-06-04 Fremgangsmaade til fremstilling af derivater af ml-236b-carboxylsyre
MX819478U MX7065E (es) 1980-06-06 1981-06-04 Un procedimiento microbiologico para preparar derivados de ml-236b
ES502827A ES502827A0 (es) 1980-06-06 1981-06-05 Procedimiento de preparar acidos hidroxicarboxilicos y sus derivados.
US06/270,846 US4346227A (en) 1980-06-06 1981-06-05 ML-236B Derivatives and their preparation
FR8111190A FR2483912B1 (fr) 1980-06-06 1981-06-05 Derives hydroxycarboxyles du compose ml-236b, leur procede de preparation et leur application therapeutique
FI811762A FI71168C (fi) 1980-06-06 1981-06-05 Foerfarande foer framstaellning av ml-236b-derivat vilka anvaends som laekemedel
NL8102737A NL191738C (nl) 1980-06-06 1981-06-05 ML-236B-derivaten, werkwijze voor hun bereiding en farmaceutische preparaten, die deze derivaten bevatten.
IT67777/81A IT1144598B (it) 1980-06-06 1981-06-05 Composti farmaceutici atti ad inibire la biosintesi del colesterolo e procedimento per la loro preparazione
AU71376/81A AU549988B2 (en) 1980-06-06 1981-06-05 Hydroxy esters
SE8103560A SE453389B (sv) 1980-06-06 1981-06-05 Hydroxikarboxylsyror, ringslutna laktoner, salter och estrar derav samt forfarande for framstellning av nemnda foreningar
KR1019810002023A KR840001055B1 (ko) 1980-06-06 1981-06-05 Ml-236b 유도체의 제조방법
DE19813122499 DE3122499A1 (de) 1980-06-06 1981-06-05 Neue derivate von ml-236b, verfahren zu ihrer herstellung und diese derivate enthaltende arzneimittelzubereitungen
IE1257/81A IE51270B1 (en) 1980-06-06 1981-06-05 Ml-236b derivatives and their preparation
CH3722/81A CH655090A5 (de) 1980-06-06 1981-06-05 Hexahydronaphthalinderivate und ihre herstellung.
GB8117450A GB2077264B (en) 1980-06-06 1981-06-08 Ml-236b derivatives and their preparation
CA000379232A CA1150170A (en) 1980-06-06 1981-06-08 Ml-236b derivatives and their preparation
BE0/205046A BE889150A (fr) 1980-06-06 1981-06-09 Derives hydroxycarboxyles du compose ml-236b, leur procede de preparation et leur application therapeutique
AT0256781A AT374495B (de) 1980-06-06 1981-06-09 Verfahren zur herstellung neuer derivate der verbindung ml-236b
US06/351,974 US4410629A (en) 1980-06-06 1982-02-24 ML-236B Derivatives and their preparation
US06/351,975 US4448979A (en) 1980-06-06 1982-02-24 ML-236B Derivatives
MX9203563A MX9203563A (es) 1980-06-06 1992-06-26 Derivados de ml-236b y su preparacion.
NL960028C NL960028I2 (nl) 1980-06-06 1996-11-18 ML-236B-derivaten, werkwijze voor hun bereiding enfarmaceutische preparaten, die deze derivaten bevatten.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7612780A JPS572240A (en) 1980-06-06 1980-06-06 Ml-236b derivative

Publications (2)

Publication Number Publication Date
JPS572240A true JPS572240A (en) 1982-01-07
JPS6113699B2 JPS6113699B2 (enExample) 1986-04-15

Family

ID=13596258

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7612780A Granted JPS572240A (en) 1980-06-06 1980-06-06 Ml-236b derivative

Country Status (1)

Country Link
JP (1) JPS572240A (enExample)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61158237A (ja) * 1984-12-28 1986-07-17 Sony Corp デ−タ通信方法
JPS62227236A (ja) * 1986-03-29 1987-10-06 Omron Tateisi Electronics Co 複数の装置相互間のデ−タ伝送システム
JPH0251582A (ja) * 1988-08-12 1990-02-21 Kyokado Eng Co Ltd 地盤注入用薬液
JP2003506424A (ja) * 1999-08-06 2003-02-18 エルイーケー ファーマシューティカル アンド ケミカル カンパニー ディー．ディー． プラバスタチンナトリウムの結晶
WO2005058316A1 (ja) * 2003-12-17 2005-06-30 Dainippon Sumitomo Pharma Co., Ltd. 合剤および併用剤
US7056710B2 (en) 2000-04-18 2006-06-06 Sankyo Company, Limited Methods for producing ML-236B, a pravastatin precursor, using a host cell transformed with mlcR, a transcription factor
WO2008001499A1 (en) 2006-06-29 2008-01-03 Kowa Co., Ltd. Prophylactic and/or therapeutic agent for rheumatoid arthritis
WO2008139703A1 (ja) 2007-04-27 2008-11-20 Kyushu University, National University Corporation 肺疾患治療薬
JP2009268479A (ja) * 2000-10-05 2009-11-19 Teva Gyogyszergyar Zartkoruen Mukodo Rt プラバスタチンラクトン及びエピプラバスタチンを実質的に含まないプラバスタチンナトリウムの製造方法
US7923573B2 (en) 2004-10-27 2011-04-12 Daiichi Sankyo Company, Limited Benzene compound having 2 or more substituents
WO2011074690A1 (en) 2009-12-14 2011-06-23 Kyoto University Pharmaceutical composition for prevention and treatment of amyotrophic lateral sclerosis
WO2015083582A1 (ja) 2013-12-02 2015-06-11 国立大学法人京都大学 Ｆｇｆｒ３病の予防および治療剤ならびにそのスクリーニング方法
WO2019216313A1 (ja) 2018-05-08 2019-11-14 国立大学法人岡山大学 心血管疾患に有用な医薬
WO2020017575A1 (ja) 2018-07-19 2020-01-23 国立大学法人京都大学 多能性幹細胞由来の板状軟骨およびその製造方法
WO2020130147A1 (ja) 2018-12-21 2020-06-25 国立大学法人京都大学 ルブリシン局在軟骨様組織、その製造方法及びそれを含む関節軟骨損傷治療用組成物
WO2020184703A1 (ja) 2019-03-13 2020-09-17 国立大学法人浜松医科大学 大動脈瘤の治療用医薬組成物
WO2021167088A1 (ja) 2020-02-21 2021-08-26 良和 中岡 肺高血圧症改善用組成物、肺高血圧症の予後予測方法、肺高血圧症の重症度判定補助方法および肺高血圧症の診断補助方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101646442B (zh) 2007-02-23 2013-09-04 21世纪国际新技术株式会社 血管痉挛的治疗剂或预防剂
US9006412B2 (en) 2008-10-06 2015-04-14 Microbiopharm Japan Co., Ltd. Expression vector for pseudonocardia autotrophica

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61158237A (ja) * 1984-12-28 1986-07-17 Sony Corp デ−タ通信方法
JPS62227236A (ja) * 1986-03-29 1987-10-06 Omron Tateisi Electronics Co 複数の装置相互間のデ−タ伝送システム
JPH0251582A (ja) * 1988-08-12 1990-02-21 Kyokado Eng Co Ltd 地盤注入用薬液
JP2003506424A (ja) * 1999-08-06 2003-02-18 エルイーケー ファーマシューティカル アンド ケミカル カンパニー ディー．ディー． プラバスタチンナトリウムの結晶
US7056710B2 (en) 2000-04-18 2006-06-06 Sankyo Company, Limited Methods for producing ML-236B, a pravastatin precursor, using a host cell transformed with mlcR, a transcription factor
JP2015212300A (ja) * 2000-10-05 2015-11-26 テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ プラバスタチンラクトン及びエピプラバスタチンを実質的に含まないプラバスタチンナトリウムの製造方法
JP2009268479A (ja) * 2000-10-05 2009-11-19 Teva Gyogyszergyar Zartkoruen Mukodo Rt プラバスタチンラクトン及びエピプラバスタチンを実質的に含まないプラバスタチンナトリウムの製造方法
WO2005058316A1 (ja) * 2003-12-17 2005-06-30 Dainippon Sumitomo Pharma Co., Ltd. 合剤および併用剤
US7923573B2 (en) 2004-10-27 2011-04-12 Daiichi Sankyo Company, Limited Benzene compound having 2 or more substituents
WO2008001499A1 (en) 2006-06-29 2008-01-03 Kowa Co., Ltd. Prophylactic and/or therapeutic agent for rheumatoid arthritis
WO2008139703A1 (ja) 2007-04-27 2008-11-20 Kyushu University, National University Corporation 肺疾患治療薬
WO2011074690A1 (en) 2009-12-14 2011-06-23 Kyoto University Pharmaceutical composition for prevention and treatment of amyotrophic lateral sclerosis
WO2015083582A1 (ja) 2013-12-02 2015-06-11 国立大学法人京都大学 Ｆｇｆｒ３病の予防および治療剤ならびにそのスクリーニング方法
EP3513789A2 (en) 2013-12-02 2019-07-24 Kyoto University Prophylactic and therapeutic agents for fgfr3 diseases
WO2019216313A1 (ja) 2018-05-08 2019-11-14 国立大学法人岡山大学 心血管疾患に有用な医薬
WO2020017575A1 (ja) 2018-07-19 2020-01-23 国立大学法人京都大学 多能性幹細胞由来の板状軟骨およびその製造方法
WO2020130147A1 (ja) 2018-12-21 2020-06-25 国立大学法人京都大学 ルブリシン局在軟骨様組織、その製造方法及びそれを含む関節軟骨損傷治療用組成物
WO2020184703A1 (ja) 2019-03-13 2020-09-17 国立大学法人浜松医科大学 大動脈瘤の治療用医薬組成物
WO2021167088A1 (ja) 2020-02-21 2021-08-26 良和 中岡 肺高血圧症改善用組成物、肺高血圧症の予後予測方法、肺高血圧症の重症度判定補助方法および肺高血圧症の診断補助方法

Also Published As

Publication number Publication date
JPS6113699B2 (enExample) 1986-04-15

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