US4357311A
(en)
*
|
1980-10-03 |
1982-11-02 |
Warner-Lambert Company |
Substrate for immunoassay and means of preparing same
|
YU43849B
(en)
*
|
1983-08-09 |
1989-12-31 |
Akad Wissenschaften |
Process for preparing macromolecular substances with chemically active filling substances
|
US4719176A
(en)
*
|
1983-10-31 |
1988-01-12 |
Klotz Irving M |
Enzyme-free diagnostic binding reagents
|
US4693985A
(en)
*
|
1984-08-21 |
1987-09-15 |
Pall Corporation |
Methods of concentrating ligands and active membranes used therefor
|
US4970300A
(en)
*
|
1985-02-01 |
1990-11-13 |
New York University |
Modified factor VIII
|
DE3515586A1
(de)
*
|
1985-04-30 |
1986-11-06 |
Boehringer Mannheim Gmbh, 6800 Mannheim |
Stabilisiertes sarcosinoxidase-praeparat
|
US4886836A
(en)
*
|
1987-06-03 |
1989-12-12 |
Pall Corporation |
Activated medium with low non-specific protein adsorption
|
US5192507A
(en)
*
|
1987-06-05 |
1993-03-09 |
Arthur D. Little, Inc. |
Receptor-based biosensors
|
US5001048A
(en)
*
|
1987-06-05 |
1991-03-19 |
Aurthur D. Little, Inc. |
Electrical biosensor containing a biological receptor immobilized and stabilized in a protein film
|
US4961852A
(en)
*
|
1987-09-14 |
1990-10-09 |
Gelman Sciences, Inc. |
Polyaldehyde activated membranes
|
US4992172A
(en)
*
|
1987-09-14 |
1991-02-12 |
Gelman Sciences, Inc. |
Blotting methods using polyaldehyde activated membranes
|
US5160626A
(en)
*
|
1987-09-14 |
1992-11-03 |
Gelman Sciences Inc. |
Blotting methods using polyaldehyde activated membranes
|
AU4529289A
(en)
*
|
1988-10-17 |
1990-05-14 |
Sepracor, Inc. |
Process for the covalent surface modification of hydrophobic polymers and articles made therefrom
|
JPH02219571A
(ja)
*
|
1989-02-20 |
1990-09-03 |
Kanebo Ltd |
修飾プロテアーゼ及びその製造法
|
US5116964A
(en)
|
1989-02-23 |
1992-05-26 |
Genentech, Inc. |
Hybrid immunoglobulins
|
AU5334190A
(en)
*
|
1989-04-04 |
1990-11-05 |
Eva Mann-Buxbaum |
Process for immobilizing proteins, peptides, coenzymes, etc. on a substrate
|
DE4005927A1
(de)
*
|
1990-02-25 |
1991-08-29 |
Roehm Gmbh |
Immobilisierung von proteinen an traegern
|
US5133968A
(en)
*
|
1990-08-20 |
1992-07-28 |
Kanebo, Ltd. |
Modified protease, method of producing the same and cosmetic products containing the modified protease
|
US5436147A
(en)
*
|
1991-03-01 |
1995-07-25 |
Nucleic Assays Corporation |
Heterobifunctional crosslinked agents for immobilizing molecules on plastic substrates
|
US5279955A
(en)
*
|
1991-03-01 |
1994-01-18 |
Pegg Randall K |
Heterofunctional crosslinking agent for immobilizing reagents on plastic substrates
|
GB2267502B
(en)
*
|
1992-05-28 |
1997-01-22 |
Aligena Ag |
Polymeric reaction products for use in immobilized buffered gels and membranes
|
IL104734A0
(en)
*
|
1993-02-15 |
1993-06-10 |
Univ Bar Ilan |
Bioactive conjugates of cellulose with amino compounds
|
JP2871435B2
(ja)
*
|
1993-04-22 |
1999-03-17 |
イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー |
親水性ポリマー被覆パーフルオロカーボンポリマーベースのマトリックスの製造方法
|
US6057287A
(en)
*
|
1994-01-11 |
2000-05-02 |
Dyax Corp. |
Kallikrein-binding "Kunitz domain" proteins and analogues thereof
|
DK0739355T3
(da)
|
1994-01-11 |
2005-01-24 |
Dyax Corp |
Kallikrein-inhiberende "Kunitz-domæne"-proteiner og analoger deraf
|
US6045797A
(en)
*
|
1994-03-14 |
2000-04-04 |
New York University Medical Center |
Treatment or diagnosis of diseases or conditions associated with a BLM domain
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
US5561097A
(en)
*
|
1994-04-28 |
1996-10-01 |
Minnesota Mining And Manufacturing Company |
Method of controlling density of ligand coupled onto supports and products produced therefrom
|
US5708142A
(en)
|
1994-05-27 |
1998-01-13 |
Genentech, Inc. |
Tumor necrosis factor receptor-associated factors
|
US5837815A
(en)
*
|
1994-12-15 |
1998-11-17 |
Sugen, Inc. |
PYK2 related polypeptide products
|
US5837524A
(en)
*
|
1994-12-15 |
1998-11-17 |
Sugen, Inc. |
PYK2 related polynucleotide products
|
US5807989A
(en)
*
|
1994-12-23 |
1998-09-15 |
New York University |
Methods for treatment or diagnosis of diseases or disorders associated with an APB domain
|
US6300482B1
(en)
*
|
1995-01-03 |
2001-10-09 |
Max-Flanck-Gesellschaft Zuer For{Overscore (D)}Erung Der |
MDKI, a novel receptor tyrosine kinase
|
US6020473A
(en)
*
|
1995-08-25 |
2000-02-01 |
Genentech, Inc. |
Nucleic acids encoding variants of vascular endothelial cell growth factor
|
US7005505B1
(en)
|
1995-08-25 |
2006-02-28 |
Genentech, Inc. |
Variants of vascular endothelial cell growth factor
|
WO1997010337A1
(en)
|
1995-09-15 |
1997-03-20 |
Baylor College Of Medicine |
Steroid receptor coactivator compositions and methods of use
|
US6030945A
(en)
*
|
1996-01-09 |
2000-02-29 |
Genentech, Inc. |
Apo-2 ligand
|
US6998116B1
(en)
*
|
1996-01-09 |
2006-02-14 |
Genentech, Inc. |
Apo-2 ligand
|
US6046048A
(en)
*
|
1996-01-09 |
2000-04-04 |
Genetech, Inc. |
Apo-2 ligand
|
US20050089958A1
(en)
*
|
1996-01-09 |
2005-04-28 |
Genentech, Inc. |
Apo-2 ligand
|
US6262017B1
(en)
|
1996-01-16 |
2001-07-17 |
Research Corporation Technologies, Inc. |
Peptides for altering osteoblast adhesion
|
US20020165157A1
(en)
*
|
1996-04-01 |
2002-11-07 |
Genentech, Inc. |
Apo-2LI and Apo-3 polypeptides
|
JP2000507829A
(ja)
*
|
1996-04-01 |
2000-06-27 |
ジェネンテック インコーポレーテッド |
Apo―2liおよびapo―3アポトーシスポリペプチド
|
US6100071A
(en)
|
1996-05-07 |
2000-08-08 |
Genentech, Inc. |
Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production
|
US6159462A
(en)
*
|
1996-08-16 |
2000-12-12 |
Genentech, Inc. |
Uses of Wnt polypeptides
|
US5851984A
(en)
*
|
1996-08-16 |
1998-12-22 |
Genentech, Inc. |
Method of enhancing proliferation or differentiation of hematopoietic stem cells using Wnt polypeptides
|
US6462176B1
(en)
|
1996-09-23 |
2002-10-08 |
Genentech, Inc. |
Apo-3 polypeptide
|
DE69737457T2
(de)
|
1997-01-31 |
2007-11-29 |
Genentech, Inc., South San Francisco |
O-fukosyltransferase
|
US20040241645A1
(en)
*
|
1997-01-31 |
2004-12-02 |
Genentech, Inc. |
O-fucosyltransferase
|
US20020102706A1
(en)
*
|
1997-06-18 |
2002-08-01 |
Genentech, Inc. |
Apo-2DcR
|
US6342369B1
(en)
*
|
1997-05-15 |
2002-01-29 |
Genentech, Inc. |
Apo-2-receptor
|
DE69838249T3
(de)
*
|
1997-05-15 |
2012-01-19 |
Genentech, Inc. |
Anti-apo-2 antikörper
|
US20100152426A1
(en)
*
|
1997-05-15 |
2010-06-17 |
Ashkenazi Avi J |
Apo-2 receptor fusion proteins
|
US6291643B1
(en)
|
1997-06-05 |
2001-09-18 |
Board Of Reports, The University Of Texas System |
Apaf-1 an activator of caspase-3
|
JP2002508663A
(ja)
*
|
1997-06-18 |
2002-03-19 |
ジェネンテク,インコーポレイテッド |
Apo−2DcR
|
WO1999002192A1
(en)
*
|
1997-07-11 |
1999-01-21 |
Brandeis University |
Method of inducing apoptosis by reducing the level of thiamin
|
PT1009817E
(pt)
*
|
1997-08-26 |
2009-12-30 |
Genentech Inc |
Receptor de rtd
|
US20030175856A1
(en)
*
|
1997-08-26 |
2003-09-18 |
Genetech, Inc. |
Rtd receptor
|
US20060141036A1
(en)
*
|
1997-12-12 |
2006-06-29 |
Andrx Labs Llc |
HMG-CoA reductase inhibitor extended release formulation
|
ES2316182T3
(es)
|
1998-01-15 |
2009-04-01 |
Genentech, Inc. |
Ligando apo-2.
|
JP2002517223A
(ja)
*
|
1998-06-12 |
2002-06-18 |
ジェネンテック・インコーポレーテッド |
モノクローナル抗体、交叉反応性抗体およびそれを生成する方法
|
US6984719B1
(en)
|
1998-09-17 |
2006-01-10 |
Hospital Sainte-Justine |
Peptide antagonists of prostaglandin F2α receptor
|
US6368793B1
(en)
*
|
1998-10-14 |
2002-04-09 |
Microgenomics, Inc. |
Metabolic selection methods
|
PT1783222E
(pt)
|
1998-10-23 |
2012-07-26 |
Kirin Amgen Inc |
Péptidos diméricos de trombopoietina que simulam a ligação ao receptor mpl e têm actividade trombopoiética
|
US6660843B1
(en)
*
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
US6982153B1
(en)
*
|
1998-12-03 |
2006-01-03 |
Targanta Therapeutics, Inc. |
DNA sequences from staphylococcus aureus bacteriophage 77 that encode anti-microbial polypeptides
|
US6861442B1
(en)
|
1998-12-30 |
2005-03-01 |
Sugen, Inc. |
PYK2 and inflammation
|
CN1370238A
(zh)
*
|
1999-06-16 |
2002-09-18 |
艾科斯有限公司 |
人聚(adp-核酸)聚合酶2的物质和方法
|
US20040235749A1
(en)
*
|
1999-09-15 |
2004-11-25 |
Sylvain Chemtob |
G-protein coupled receptor antagonists
|
US20030138771A1
(en)
*
|
1999-09-30 |
2003-07-24 |
Jerry Pelletier |
DNA sequences from S. pneumoniae bacteriophage DP1 that encode anti-microbal polypeptides
|
US6808902B1
(en)
|
1999-11-12 |
2004-10-26 |
Amgen Inc. |
Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
|
KR100749982B1
(ko)
|
1999-11-16 |
2007-08-16 |
제넨테크, 인크. |
혈관 내피 성장 인자용 elisa
|
FR2803926B1
(fr)
*
|
2000-01-14 |
2002-04-05 |
Thomson Csf Sextant |
Procede de generation automatique de table de symboles d'un calculateur temps reel
|
JP4541490B2
(ja)
*
|
2000-04-07 |
2010-09-08 |
株式会社カネカ |
拡張型心筋症用吸着体
|
EP1290013B1
(en)
|
2000-04-21 |
2006-03-08 |
Amgen Inc. |
Apo-ai/aii peptide derivatives
|
US6667300B2
(en)
|
2000-04-25 |
2003-12-23 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
US6677136B2
(en)
|
2000-05-03 |
2004-01-13 |
Amgen Inc. |
Glucagon antagonists
|
US20030012782A1
(en)
*
|
2000-08-11 |
2003-01-16 |
Gold Daniel P. |
Method and composition for altering a T cell mediated pathology
|
US6911204B2
(en)
*
|
2000-08-11 |
2005-06-28 |
Favrille, Inc. |
Method and composition for altering a B cell mediated pathology
|
CN1970077A
(zh)
|
2001-05-11 |
2007-05-30 |
安姆根有限公司 |
与tall-1结合的肽和相关分子
|
US7138370B2
(en)
|
2001-10-11 |
2006-11-21 |
Amgen Inc. |
Specific binding agents of human angiopoietin-2
|
US7332474B2
(en)
*
|
2001-10-11 |
2008-02-19 |
Amgen Inc. |
Peptides and related compounds having thrombopoietic activity
|
US20040054082A1
(en)
*
|
2001-12-03 |
2004-03-18 |
Bank David H |
Toughened polymer blends with improved surface properties
|
US20100311954A1
(en)
*
|
2002-03-01 |
2010-12-09 |
Xencor, Inc. |
Optimized Proteins that Target Ep-CAM
|
US7153829B2
(en)
|
2002-06-07 |
2006-12-26 |
Dyax Corp. |
Kallikrein-inhibitor therapies
|
PT1941867E
(pt)
|
2002-06-07 |
2012-02-16 |
Dyax Corp |
Polipeptídeo contendo um domínio kunitz modificado
|
US7521530B2
(en)
|
2002-06-11 |
2009-04-21 |
Universite De Montreal |
Peptides and peptidomimetics useful for inhibiting the activity of prostaglandin F2α receptor
|
WO2004019968A1
(en)
*
|
2002-08-28 |
2004-03-11 |
Dyax Corp. |
Methods for preserving organs and tissues
|
US6919426B2
(en)
|
2002-09-19 |
2005-07-19 |
Amgen Inc. |
Peptides and related molecules that modulate nerve growth factor activity
|
WO2005016349A1
(en)
*
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Methods of inhibiting leukocyte accumulation
|
US20050043239A1
(en)
*
|
2003-08-14 |
2005-02-24 |
Jason Douangpanya |
Methods of inhibiting immune responses stimulated by an endogenous factor
|
US8883147B2
(en)
|
2004-10-21 |
2014-11-11 |
Xencor, Inc. |
Immunoglobulins insertions, deletions, and substitutions
|
US8399618B2
(en)
|
2004-10-21 |
2013-03-19 |
Xencor, Inc. |
Immunoglobulin insertions, deletions, and substitutions
|
US20060134105A1
(en)
*
|
2004-10-21 |
2006-06-22 |
Xencor, Inc. |
IgG immunoglobulin variants with optimized effector function
|
CA2540921A1
(en)
*
|
2003-10-22 |
2005-09-01 |
Merz Pharma Gmbh & Co. Kgaa |
The use of 1-aminocyclohexane derivatives to modify deposition of fibrillogenic ass peptides in amyloidopathies
|
EP1700108A1
(en)
*
|
2003-12-30 |
2006-09-13 |
3M Innovative Properties Company |
Surface acoustic wave sensor assemblies
|
US20070245810A1
(en)
*
|
2003-12-30 |
2007-10-25 |
Carter Chad J |
Detection Cartridges, Modules, Systems and Methods
|
US7658994B2
(en)
*
|
2003-12-30 |
2010-02-09 |
3M Innovative Properties Company |
Substrates and compounds bonded thereto
|
WO2005066636A1
(en)
*
|
2003-12-30 |
2005-07-21 |
3M Innovative Properties Company |
Substrates and compounds bonded thereto
|
EP1732947B1
(en)
*
|
2004-03-05 |
2011-04-27 |
Vegenics Pty Ltd |
Growth factor binding constructs materials and methods
|
KR20070012826A
(ko)
*
|
2004-04-16 |
2007-01-29 |
제넨테크, 인크. |
항체에 대한 분석법
|
PT3153514T
(pt)
|
2004-05-13 |
2021-06-25 |
Icos Corp |
Quinazolinonas como inibidoras da fosfatidilinositol 3-quinase delta humana
|
EP1769243A2
(en)
*
|
2004-05-15 |
2007-04-04 |
Genentech, Inc. |
Cross-screening system and methods for detecting a molecule having binding affinity for a target molecule
|
JP2008500338A
(ja)
*
|
2004-05-25 |
2008-01-10 |
イコス・コーポレイション |
造血細胞の異常増殖を治療及び/又は予防する方法
|
JP2008505928A
(ja)
*
|
2004-07-08 |
2008-02-28 |
アムジェン インコーポレーテッド |
治療用ペプチド
|
GB0416699D0
(en)
*
|
2004-07-27 |
2004-09-01 |
Prometic Biosciences Ltd |
Prion protein ligands and methods of use
|
CA2580796C
(en)
*
|
2004-09-24 |
2013-03-26 |
Amgen Inc. |
Modified fc molecules having peptides inserted in internal loop regions
|
US7235530B2
(en)
*
|
2004-09-27 |
2007-06-26 |
Dyax Corporation |
Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
|
DK1817340T3
(da)
|
2004-11-12 |
2012-08-13 |
Xencor Inc |
Fc-varianter med ændret binding til fcrn
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
NZ556635A
(en)
|
2004-12-22 |
2010-11-26 |
Genentech Inc |
Method for producing soluble multi-membrane-spanning proteins
|
US20080287469A1
(en)
*
|
2005-02-17 |
2008-11-20 |
Diacovo Thomas G |
Phosphoinositide 3-Kinase Inhibitors for Inhibiting Leukocyte Accumulation
|
WO2006131768A2
(en)
*
|
2005-06-10 |
2006-12-14 |
Prometic Biosciences Limited |
Triazines as protein binding ligands
|
EP2004695A2
(en)
|
2005-07-08 |
2008-12-24 |
Xencor, Inc. |
Optimized anti-ep-cam antibodies
|
US8008453B2
(en)
|
2005-08-12 |
2011-08-30 |
Amgen Inc. |
Modified Fc molecules
|
US20070161089A1
(en)
*
|
2005-11-08 |
2007-07-12 |
Genentech, Inc. |
Method of Producing Pan-Specific Antibodies
|
PE20070684A1
(es)
|
2005-11-14 |
2007-08-06 |
Amgen Inc |
MOLECULAS QUIMERICAS DE ANTICUERPO RANKL-PTH/PTHrP
|
US7276480B1
(en)
|
2005-12-30 |
2007-10-02 |
Dyax Corp. |
Prevention and reduction of blood loss
|
WO2007102946A2
(en)
|
2006-01-23 |
2007-09-13 |
Amgen Inc. |
Crystalline polypeptides
|
CA2643693A1
(en)
*
|
2006-03-10 |
2007-09-20 |
Dyax Corp. |
Formulations for ecallantide
|
JO3324B1
(ar)
|
2006-04-21 |
2019-03-13 |
Amgen Inc |
مركبات علاجية مجففة بالتبريد تتعلق بالعصارة الهضمية
|
US7981425B2
(en)
*
|
2006-06-19 |
2011-07-19 |
Amgen Inc. |
Thrombopoietic compounds
|
US20080096900A1
(en)
|
2006-06-26 |
2008-04-24 |
Amgen Inc. |
Methods for treating atherosclerosis
|
JP5502480B2
(ja)
|
2006-09-18 |
2014-05-28 |
コンピュゲン エルティーディー. |
生物活性ペプチド及びその使用方法
|
US7833527B2
(en)
|
2006-10-02 |
2010-11-16 |
Amgen Inc. |
Methods of treating psoriasis using IL-17 Receptor A antibodies
|
EP2069798B1
(en)
|
2006-10-04 |
2014-04-16 |
Genentech, Inc. |
Elisa for vegf
|
WO2008051383A2
(en)
*
|
2006-10-19 |
2008-05-02 |
Amgen Inc. |
Use of alcohol co-solvents to improve pegylation reaction yields
|
TW200833840A
(en)
|
2006-10-25 |
2008-08-16 |
Amgen Inc |
Toxin peptide therapeutic agents
|
US20080171344A1
(en)
*
|
2006-12-22 |
2008-07-17 |
Kapsner Kenneth P |
Methods, Kits and Materials for Diagnosing Disease States by Measuring Isoforms or Proforms of Myeloperoxidase
|
US20100151553A1
(en)
*
|
2006-12-29 |
2010-06-17 |
Bjork Jason W |
Method of detection of bioanalytes by acousto-mechanical detection systems comprising the addition of liposomes
|
WO2008153745A2
(en)
|
2007-05-22 |
2008-12-18 |
Amgen Inc. |
Compositions and methods for producing bioactive fusion proteins
|
AU2008273813B2
(en)
|
2007-07-12 |
2013-06-13 |
Compugen Ltd. |
Bioactive peptides and method of using same
|
US8168416B2
(en)
|
2007-07-26 |
2012-05-01 |
Amgen Inc. |
Modified lecithin-cholesterol acyltransferase enzymes
|
US8715684B2
(en)
|
2007-08-28 |
2014-05-06 |
Ramot At Tel Aviv University Ltd. |
Peptides inducing a CD4i conformation in HIV gp120 while retaining vacant CD4 binding site
|
PL2808343T3
(pl)
|
2007-12-26 |
2019-11-29 |
Xencor Inc |
Warianty Fc ze zmienionym wiązaniem do FcRn
|
WO2010027802A2
(en)
*
|
2008-08-25 |
2010-03-11 |
New York University |
Methods for treating diabetic wounds
|
KR20170060179A
(ko)
|
2008-11-13 |
2017-05-31 |
길리아드 칼리스토가 엘엘씨 |
혈액 종양에 대한 요법
|
US9492449B2
(en)
|
2008-11-13 |
2016-11-15 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
CN102307594A
(zh)
*
|
2009-01-06 |
2012-01-04 |
戴埃克斯有限公司 |
用激肽释放酶抑制剂治疗粘膜炎
|
KR20120002995A
(ko)
|
2009-03-24 |
2012-01-09 |
길리아드 칼리스토가 엘엘씨 |
2―퓨리닐―3―톨릴―퀴나졸리논 유도체의 회전장애 이성질체 및 사용 방법
|
CA2759724A1
(en)
*
|
2009-04-20 |
2010-10-28 |
Calistoga Pharmaceuticals, Inc. |
Methods of treatment for solid tumors
|
WO2011011550A1
(en)
|
2009-07-21 |
2011-01-27 |
Calistoga Pharmaceuticals Inc. |
Treatment of liver disorders with pi3k inhibitors
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
WO2011049625A1
(en)
|
2009-10-20 |
2011-04-28 |
Mansour Samadpour |
Method for aflatoxin screening of products
|
MY182750A
(en)
*
|
2009-10-26 |
2021-02-05 |
Genentech Inc |
Assays for detecting antibodies specific to therapeutic anti-ige antibodies and their use in anaphylaxis
|
BR112012010640A2
(pt)
|
2009-11-05 |
2016-11-22 |
Rhizen Pharmaceuticals S A |
novos moduladores de quinase
|
CA3021759A1
(en)
|
2010-01-06 |
2011-07-14 |
Dyax Corp. |
Plasma kallikrein binding proteins
|
WO2011097527A2
(en)
|
2010-02-04 |
2011-08-11 |
Xencor, Inc. |
Immunoprotection of therapeutic moieties using enhanced fc regions
|
US20110189178A1
(en)
*
|
2010-02-04 |
2011-08-04 |
Xencor, Inc. |
Immunoprotection of Therapeutic Moieties Using Enhanced Fc Regions
|
ES2575160T3
(es)
|
2010-03-15 |
2016-06-24 |
The Board Of Trustees Of The University Of Illinois |
Inhibidores de las interacciones que unen la subunidad alfa de la beta integrina-proteína G
|
WO2011145035A1
(en)
|
2010-05-17 |
2011-11-24 |
Indian Incozen Therapeutics Pvt. Ltd. |
Novel 3,5-disubstitued-3h-imidazo[4,5-b]pyridine and 3,5- disubstitued -3h-[1,2,3]triazolo[4,5-b] pyridine compounds as modulators of protein kinases
|
US9254310B2
(en)
|
2010-06-17 |
2016-02-09 |
New York University |
Therapeutic and cosmetic uses and applications of calreticulin
|
WO2012030738A2
(en)
|
2010-08-30 |
2012-03-08 |
Beckman Coulter, Inc. |
Complex phosphoprotein activation profiles
|
WO2012045085A1
(en)
|
2010-10-01 |
2012-04-05 |
Oxford Biotherapeutics Ltd. |
Anti-rori antibodies
|
EP2655401B1
(en)
|
2010-12-20 |
2016-03-09 |
The Regents of the University of Michigan |
Inhibitors of the epidermal growth factor receptor-heat shock protein 90 binding interaction
|
JOP20210044A1
(ar)
|
2010-12-30 |
2017-06-16 |
Takeda Pharmaceuticals Co |
الأجسام المضادة لـ cd38
|
WO2012094587A1
(en)
|
2011-01-06 |
2012-07-12 |
Dyax Corp. |
Plasma kallikrein binding proteins
|
EA201391331A1
(ru)
|
2011-03-16 |
2014-02-28 |
Эмджен Инк. |
Активные и селективные ингибиторы nav1.3 и nav1.7
|
EP2702076A1
(en)
|
2011-04-29 |
2014-03-05 |
Bristol-Myers Squibb Company |
Ip-10 antibody dosage escalation regimens
|
JP6118314B2
(ja)
|
2011-05-04 |
2017-04-19 |
ライゼン・ファーマシューティカルズ・エスアー |
タンパク質キナーゼのモジュレーターとしての新規化合物
|
WO2013016220A1
(en)
|
2011-07-22 |
2013-01-31 |
Amgen Inc. |
Il-17 receptor a is required for il-17c biology
|
KR102007055B1
(ko)
|
2011-09-22 |
2019-08-02 |
암젠 인크 |
Cd27l 항원 결합 단백질
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
EA201691327A1
(ru)
|
2012-03-05 |
2017-03-31 |
Джилид Калистога Ллс |
Полиморфные формы (s)-2-(1-(9h-пурин-6-иламино)пропил)-5-фтор-3-фенилхиназолин-4(3h)-она
|
US20150079100A1
(en)
|
2012-03-23 |
2015-03-19 |
Bristol-Myers Squibb Company |
Methods of treatments using ctla-4 antibodies
|
JP2015518471A
(ja)
|
2012-03-28 |
2015-07-02 |
ジェネンテック, インコーポレイテッド |
抗hcmvイディオタイプ抗体およびそれらの使用
|
JP6192708B2
(ja)
|
2012-03-30 |
2017-09-06 |
ライゼン・ファーマシューティカルズ・エスアー |
C−metプロテインキナーゼ調節物質としての新規3,5−二置換−3h−イミダゾ[4,5−b]ピリジン化合物および3,5−二置換−3h−[1,2,3]トリアゾロ[4,5−b]ピリジン化合物
|
WO2013155346A1
(en)
|
2012-04-11 |
2013-10-17 |
The Regents Of The University Of California |
Diagnostic tools for response to 6-thiopurine therapy
|
UY34813A
(es)
|
2012-05-18 |
2013-11-29 |
Amgen Inc |
Proteínas de unión a antígeno dirigidas contra el receptor st2
|
TW201425336A
(zh)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Bcma抗原結合蛋白質
|
WO2014099984A1
(en)
|
2012-12-20 |
2014-06-26 |
Amgen Inc. |
Apj receptor agonists and uses thereof
|
JO3519B1
(ar)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
ES2728936T3
(es)
|
2013-01-25 |
2019-10-29 |
Amgen Inc |
Anticuerpos dirigidos contra CDH19 para melanoma
|
EP2954332A1
(en)
|
2013-02-06 |
2015-12-16 |
Pieris AG |
Novel lipocalin-mutein assays for measuring hepcidin concentration
|
PH12015501785B1
(en)
|
2013-02-18 |
2024-02-16 |
Vegenics Pty Ltd |
Ligand binding molecules and uses thereof
|
TW201446792A
(zh)
|
2013-03-12 |
2014-12-16 |
Amgen Inc |
Nav1.7之強效及選擇性抑制劑
|
US9580486B2
(en)
|
2013-03-14 |
2017-02-28 |
Amgen Inc. |
Interleukin-2 muteins for the expansion of T-regulatory cells
|
TW201525001A
(zh)
|
2013-03-15 |
2015-07-01 |
Amgen Res Munich Gmbh |
包含n-端abp之單鏈結合分子
|
EP2970486B1
(en)
|
2013-03-15 |
2018-05-16 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
US9260527B2
(en)
|
2013-03-15 |
2016-02-16 |
Sdix, Llc |
Anti-human CXCR4 antibodies and methods of making same
|
EP2970446A1
(en)
|
2013-03-15 |
2016-01-20 |
Amgen Research (Munich) GmbH |
Antibody constructs for influenza m2 and cd3
|
PL3587448T3
(pl)
|
2013-03-15 |
2021-11-29 |
Xencor, Inc. |
Białka heterodimeryczne
|
JP6603207B2
(ja)
|
2013-03-15 |
2019-11-06 |
ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム |
ヌトリン3aおよびペプチドを用いた肺線維症の阻害
|
EP4349864A3
(en)
|
2013-05-30 |
2024-06-26 |
Kiniksa Pharmaceuticals, Ltd. |
Oncostatin m receptor antigen binding proteins
|
WO2015035076A1
(en)
*
|
2013-09-04 |
2015-03-12 |
Sten Ohlson |
Weak affinity chromatography
|
EP3055695A1
(en)
|
2013-09-12 |
2016-08-17 |
Institut National de la Santé et de la Recherche Médicale |
Method for in vitro quantifying allo-antibodies, auto-antibodies and/or therapeutic antibodies
|
AU2014318615B2
(en)
|
2013-09-13 |
2020-03-12 |
Genentech, Inc. |
Methods and compositions comprising purified recombinant polypeptides
|
AR097648A1
(es)
|
2013-09-13 |
2016-04-06 |
Amgen Inc |
Combinación de factores epigenéticos y compuestos biespecíficos que tienen como diana cd33 y cd3 en el tratamiento de leucemia mieloide
|
MX2016002799A
(es)
|
2013-09-13 |
2016-05-26 |
Genentech Inc |
Composiciones y metodos para detectar y cuantificar la proteina en la celula hospedera en las lineas de celulas y productos de polipeptidos recombinantes.
|
US10081682B2
(en)
|
2013-10-11 |
2018-09-25 |
Oxford Bio Therapeutics Ltd. |
Conjugated antibodies against LY75 for the treatment of cancer
|
NZ736970A
(en)
|
2013-12-20 |
2018-11-30 |
Gilead Calistoga Llc |
Process methods for phosphatidylinositol 3-kinase inhibitors
|
WO2015095605A1
(en)
|
2013-12-20 |
2015-06-25 |
Gilead Calistoga Llc |
Polymorphic forms of a hydrochloride salt of (s) -2-(9h-purin-6-ylamino) propyl) -5-fluoro-3-phenylquinazolin-4 (3h) -one
|
EP3094976B1
(en)
|
2014-01-17 |
2020-03-25 |
Minomic International Ltd. |
Cell surface prostate cancer antigen for diagnosis
|
WO2015127134A2
(en)
|
2014-02-20 |
2015-08-27 |
Allergan, Inc. |
Complement component c5 antibodies
|
CN106232624B
(zh)
|
2014-02-27 |
2020-01-21 |
阿勒根公司 |
补体因子Bb抗体
|
KR102555955B1
(ko)
|
2014-03-27 |
2023-07-18 |
다케다 파머수티컬 컴패니 리미티드 |
당뇨병성 황반 부종의 치료를 위한 조성물 및 방법
|
DK3122781T3
(da)
|
2014-03-28 |
2020-03-16 |
Xencor Inc |
Bispecifikke antistoffer, der binder til cd38 og cd3
|
MX370689B
(es)
|
2014-06-10 |
2019-12-19 |
Amgen Inc |
Polipeptidos apelina.
|
AU2015274696B2
(en)
|
2014-06-13 |
2018-09-27 |
Gilead Sciences, Inc. |
Phosphatidylinositol 3-kinase inhibitors
|
EP3174901B1
(en)
|
2014-07-31 |
2019-06-26 |
Amgen Research (Munich) GmbH |
Optimized cross-species specific bispecific single chain antibody constructs
|
AR101400A1
(es)
|
2014-07-31 |
2016-12-14 |
Amgen Res (Munich) Gmbh |
Constructo de anticuerpo de cadena individual biespecífico con distribución mejorada de tejido
|
AR101669A1
(es)
|
2014-07-31 |
2017-01-04 |
Amgen Res (Munich) Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
WO2016141387A1
(en)
|
2015-03-05 |
2016-09-09 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
MX381844B
(es)
|
2015-03-06 |
2025-03-13 |
Genentech Inc |
Dsba y dsbc ultrapurificado y métodos para elaborarlos y utilizarlos
|
WO2016149537A1
(en)
|
2015-03-17 |
2016-09-22 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Bank vole prion protein as a broad-spectrum substrate for rt-quic-based detection and discrimination of prion strains
|
TN2017000432A1
(en)
|
2015-04-10 |
2019-04-12 |
Amgen Inc |
Interleukin-2 muteins for the expansion of t-regulatory cells
|
LT3283524T
(lt)
|
2015-04-17 |
2023-05-25 |
Amgen Research (Munich) Gmbh |
Bispecifiniai antikūnų konstruktai, skirti cdh3 ir cd3
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Cd70及cd3抗體構築體
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Msln及cd3抗體構築體
|
TWI793062B
(zh)
|
2015-07-31 |
2023-02-21 |
德商安美基研究(慕尼黑)公司 |
Dll3及cd3抗體構築體
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
EP3341415B1
(en)
|
2015-08-28 |
2021-03-24 |
H. Hoffnabb-La Roche Ag |
Anti-hypusine antibodies and uses thereof
|
EP3387018A1
(en)
|
2015-12-11 |
2018-10-17 |
Dyax Corp. |
Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack
|
JOP20170017B1
(ar)
|
2016-01-25 |
2021-08-17 |
Amgen Res Munich Gmbh |
تركيب صيدلي يتضمن تركيبات جسم مضاد ثنائي الاختصاص
|
AR107582A1
(es)
|
2016-02-03 |
2018-05-16 |
Amgen Res Munich Gmbh |
Constructos de anticuerpo biespecíficos para psma y cd3 que se ligan a células t
|
EA039859B1
(ru)
|
2016-02-03 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
SG11201805770UA
(en)
|
2016-02-03 |
2018-08-30 |
Amgen Res Munich Gmbh |
BCMA and CD3 Bispecific T Cell Engaging Antibody Constructs
|
JOP20170091B1
(ar)
|
2016-04-19 |
2021-08-17 |
Amgen Res Munich Gmbh |
إعطاء تركيبة ثنائية النوعية ترتبط بـ cd33 وcd3 للاستخدام في طريقة لعلاج اللوكيميا النخاعية
|
EP3280725B1
(en)
|
2016-05-04 |
2020-08-26 |
Amgen Inc. |
Interleukin-2 muteins for the expansion of t-regulatory cells
|
CA3024485A1
(en)
|
2016-05-16 |
2017-11-23 |
Baxalta Incorporated |
Anti-factor ix padua antibodies
|
MA45674A
(fr)
|
2016-07-15 |
2019-05-22 |
Takeda Pharmaceuticals Co |
Méthodes et matériaux permettant d'évaluer une réponse à des traitements de déplétion de plasmoblastes et de plasmocytes
|
CN110167967B
(zh)
|
2017-01-18 |
2022-08-05 |
豪夫迈·罗氏有限公司 |
针对抗pd-l1抗体的独特型抗体及其用途
|
JOP20190189A1
(ar)
|
2017-02-02 |
2019-08-01 |
Amgen Res Munich Gmbh |
تركيبة صيدلانية ذات درجة حموضة منخفضة تتضمن بنيات جسم مضاد يستهدف الخلية t
|
GB201703876D0
(en)
|
2017-03-10 |
2017-04-26 |
Berlin-Chemie Ag |
Pharmaceutical combinations
|
SG11201909547TA
(en)
|
2017-05-05 |
2019-11-28 |
Amgen Inc |
Pharmaceutical composition comprising bispecific antibody constructs for improved storage and administration
|
CN111372950B
(zh)
|
2017-10-12 |
2024-11-05 |
免疫苏醒公司 |
Vegfr-抗体轻链融合蛋白
|
CA3082507A1
(en)
|
2017-12-11 |
2019-06-20 |
Amgen Inc. |
Continuous manufacturing process for bispecific antibody products
|
UY38041A
(es)
|
2017-12-29 |
2019-06-28 |
Amgen Inc |
Construcción de anticuerpo biespecífico dirigida a muc17 y cd3
|
BR112020022122A2
(pt)
|
2018-04-30 |
2021-01-26 |
Medimmune Limited |
conjugados para alvejamento e eliminação de agregados
|
GB201809746D0
(en)
|
2018-06-14 |
2018-08-01 |
Berlin Chemie Ag |
Pharmaceutical combinations
|
PE20211091A1
(es)
|
2018-07-02 |
2021-06-14 |
Amgen Inc |
Proteina de union al antigeno anti-steap1
|
US20210301017A1
(en)
|
2018-07-30 |
2021-09-30 |
Amgen Research (Munich) Gmbh |
Prolonged administration of a bispecific antibody construct binding to cd33 and cd3
|
WO2020077212A1
(en)
|
2018-10-11 |
2020-04-16 |
Amgen Inc. |
Downstream processing of bispecific antibody constructs
|
WO2020081493A1
(en)
|
2018-10-16 |
2020-04-23 |
Molecular Templates, Inc. |
Pd-l1 binding proteins
|
MX2021014644A
(es)
|
2019-06-13 |
2022-04-06 |
Amgen Inc |
Control de perfusion basado en biomasa automatizado en la fabricacion de productos biologicos.
|
BR112022002666A2
(pt)
|
2019-08-13 |
2022-08-09 |
Amgen Inc |
Muteínas de interleucina-2 para a expansão de células t reguladoras
|
AU2020345787A1
(en)
|
2019-09-10 |
2022-03-24 |
Amgen Inc. |
Purification method for bispecific antigen-binding polypeptides with enhanced protein L capture dynamic binding capacity
|
EP4058485A1
(en)
|
2019-11-13 |
2022-09-21 |
Amgen Inc. |
Method for reduced aggregate formation in downstream processing of bispecific antigen-binding molecules
|
MX2022007712A
(es)
|
2019-12-17 |
2022-09-26 |
Amgen Inc |
Agonista doble de interleucina-2/receptor de tnf para uso en terapia.
|
IL297672A
(en)
|
2020-04-30 |
2022-12-01 |
Genentech Inc |
Kras specific antibodies and uses thereof
|
EP4153633A1
(en)
|
2020-05-19 |
2023-03-29 |
Amgen Inc. |
Mageb2 binding constructs
|
JP2023527972A
(ja)
|
2020-05-29 |
2023-07-03 |
アムジエン・インコーポレーテツド |
Cd33及びcd3に結合する二重特異性コンストラクトの有害作用軽減投与
|
MX2022014892A
(es)
|
2020-06-01 |
2023-01-04 |
Genentech Inc |
Metodos para preparar vesiculas extracelulares y usos de estas.
|
CN116670285A
(zh)
|
2020-06-23 |
2023-08-29 |
江苏康缘药业股份有限公司 |
抗cd38抗体及其用途
|
BR112023000707A2
(pt)
|
2020-07-14 |
2023-01-31 |
Hoffmann La Roche |
Ensaio de ligação para uma combinação de dose fixa, proteína, kits, composições e métodos para avaliar uma composição de dose fixa, fazer uma composição e para analisar o teor de proteína de uma combinação de dose fixa
|
CR20230229A
(es)
|
2020-11-06 |
2023-09-05 |
Amgen Res Munich Gmbh |
Moléculas de unión a antígeno biespecíficas con múltiples dianas de selectividad aumentada
|
AU2022246675A1
(en)
|
2021-04-02 |
2023-10-19 |
Amgen Inc. |
Mageb2 binding constructs
|
IL307672A
(en)
|
2021-05-06 |
2023-12-01 |
Amgen Res Munich Gmbh |
Cd20 and cd22 targeting antigen-binding molecules for use in proliferative diseases
|
TW202346368A
(zh)
|
2022-05-12 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
具有增加的選擇性的多鏈多靶向性雙特異性抗原結合分子
|
AU2023343470A1
(en)
|
2022-09-14 |
2025-02-06 |
Amgen Inc. |
Bispecific molecule stabilizing composition
|
TW202510911A
(zh)
|
2023-06-14 |
2025-03-16 |
美商安進公司 |
T細胞接合劑掩蔽分子
|