JPS5466642A - Novel propiophenone derivative and its preparation - Google Patents
Novel propiophenone derivative and its preparationInfo
- Publication number
- JPS5466642A JPS5466642A JP12969377A JP12969377A JPS5466642A JP S5466642 A JPS5466642 A JP S5466642A JP 12969377 A JP12969377 A JP 12969377A JP 12969377 A JP12969377 A JP 12969377A JP S5466642 A JPS5466642 A JP S5466642A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- derivative
- amino
- preparation
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:A 2-methyl-3-amino-propiophenone derivative of formula I: (R is lower alkyl group) and its inorganic acid salt.
EXAMPLE: 4', 2-Dimethyl-3-amino-prpiophenone.
USE: Intermediate for synthesis of medicines e.g. antispasmodics, etc.
PROCESS: A methacylophenone derivative of formula II is reacted with an equimolar or more amount of ammonia in a solvent, e.g. a lower alkanol, etc. at normal pressure and temperature for 5W20 hr to give the 2-methyl-3-amino-propiophenone derivative of formula I and its inorganic acid salt. The starting compound of formula II can be obtained by the Friedel-Crafts reaction of methacrylic acid chloride with a commericially available benzene derivative.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12969377A JPS5466642A (en) | 1977-10-31 | 1977-10-31 | Novel propiophenone derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12969377A JPS5466642A (en) | 1977-10-31 | 1977-10-31 | Novel propiophenone derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5466642A true JPS5466642A (en) | 1979-05-29 |
Family
ID=15015847
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12969377A Pending JPS5466642A (en) | 1977-10-31 | 1977-10-31 | Novel propiophenone derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5466642A (en) |
-
1977
- 1977-10-31 JP JP12969377A patent/JPS5466642A/en active Pending
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