JPS5746948A - Production of beta- 1,2,2,-trifluoro-2-alkoxyethyl alanine derivative - Google Patents

Production of beta- 1,2,2,-trifluoro-2-alkoxyethyl alanine derivative

Info

Publication number
JPS5746948A
JPS5746948A JP12287280A JP12287280A JPS5746948A JP S5746948 A JPS5746948 A JP S5746948A JP 12287280 A JP12287280 A JP 12287280A JP 12287280 A JP12287280 A JP 12287280A JP S5746948 A JPS5746948 A JP S5746948A
Authority
JP
Japan
Prior art keywords
formula
compound
trifluoro
alkoxyethyl
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12287280A
Other languages
Japanese (ja)
Other versions
JPS5748142B2 (en
Inventor
Hiroshige Muramatsu
Akio Ueda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Institute of Advanced Industrial Science and Technology AIST
Original Assignee
Agency of Industrial Science and Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency of Industrial Science and Technology filed Critical Agency of Industrial Science and Technology
Priority to JP12287280A priority Critical patent/JPS5746948A/en
Publication of JPS5746948A publication Critical patent/JPS5746948A/en
Publication of JPS5748142B2 publication Critical patent/JPS5748142B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:Compounds of formula I (R is 1W4C straight or branched-chain alkyl).
EXAMPLE: 2-Acetylamino-4,5,5-trifluoro-5-ethoxypentanoic acid.
USE: Synthetic intermediate of fluorine-containing aminoacids or intermediate of medicines and agricultural chemicals.
PREPARATION: A β-trifluorovinylalanine derivative of formula II (R' is methyl, ethyl) and an alcohol of ROH are heated in the presence of a base such as potassium or sodium hydroxide and the reaction mixture is treated with an inorganic acid such as dilute hydrochloric acid to produce the compound of formula I. The reaction is effected by dissolving the compound of formula II in an excess amount of the alcohol (5W20 times the weight of the compound) and adding the base 1.5W2 times the molar amount of the compound of formula II. The objective compound is prepared readily by the one-step process.
COPYRIGHT: (C)1982,JPO&Japio
JP12287280A 1980-09-04 1980-09-04 Production of beta- 1,2,2,-trifluoro-2-alkoxyethyl alanine derivative Granted JPS5746948A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12287280A JPS5746948A (en) 1980-09-04 1980-09-04 Production of beta- 1,2,2,-trifluoro-2-alkoxyethyl alanine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12287280A JPS5746948A (en) 1980-09-04 1980-09-04 Production of beta- 1,2,2,-trifluoro-2-alkoxyethyl alanine derivative

Publications (2)

Publication Number Publication Date
JPS5746948A true JPS5746948A (en) 1982-03-17
JPS5748142B2 JPS5748142B2 (en) 1982-10-14

Family

ID=14846711

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12287280A Granted JPS5746948A (en) 1980-09-04 1980-09-04 Production of beta- 1,2,2,-trifluoro-2-alkoxyethyl alanine derivative

Country Status (1)

Country Link
JP (1) JPS5746948A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4511733A (en) * 1981-12-25 1985-04-16 Daikin Kogyo Co., Ltd. Fluorine-containing aminocarboxylic acid compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4511733A (en) * 1981-12-25 1985-04-16 Daikin Kogyo Co., Ltd. Fluorine-containing aminocarboxylic acid compounds

Also Published As

Publication number Publication date
JPS5748142B2 (en) 1982-10-14

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