JPS5764661A - Preparation of mercaptoamines - Google Patents
Preparation of mercaptoaminesInfo
- Publication number
- JPS5764661A JPS5764661A JP13874180A JP13874180A JPS5764661A JP S5764661 A JPS5764661 A JP S5764661A JP 13874180 A JP13874180 A JP 13874180A JP 13874180 A JP13874180 A JP 13874180A JP S5764661 A JPS5764661 A JP S5764661A
- Authority
- JP
- Japan
- Prior art keywords
- acid
- aqueous solution
- amount
- compound shown
- dividedly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To obtain a mercaptoamine useful as a raw material for drugs in high purity in high yield inexpensively, by adding dividedly an S-2-aminoethyl thiosulfate to a heated aqueous solution of an acid so that it is hydrolyzed.
CONSTITUTION: A compound shown by the formulaI(R1WR4 are H or 1W4C alkyl) is added dividedly to an aqueous solution of an acid heated at ≥80°C, and hydrolyzed to give a mercaptoamine shown by the formula II. The aqueous solution of an acid, for example, is an aqueous solution of hydrochloric acid, hydrobromic acid, sulfuric acid, etc., and the amount of the solution is preferably equimolar to the compound shown by the formulaIor more than it. The amount of disulfide as a by-product is made small and the yield is increased by adding dividedly the compound shown by the formulaIso that the amount of the unreacted raw material is made as small as possible.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13874180A JPS5764661A (en) | 1980-10-06 | 1980-10-06 | Preparation of mercaptoamines |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13874180A JPS5764661A (en) | 1980-10-06 | 1980-10-06 | Preparation of mercaptoamines |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5764661A true JPS5764661A (en) | 1982-04-19 |
Family
ID=15229082
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP13874180A Pending JPS5764661A (en) | 1980-10-06 | 1980-10-06 | Preparation of mercaptoamines |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5764661A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5256362A (en) * | 1989-07-14 | 1993-10-26 | Nippon Shokubai Co., Ltd. | Method for production of granular cysteamine hydrochloride |
-
1980
- 1980-10-06 JP JP13874180A patent/JPS5764661A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5256362A (en) * | 1989-07-14 | 1993-10-26 | Nippon Shokubai Co., Ltd. | Method for production of granular cysteamine hydrochloride |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS5738768A (en) | Preparation of optically active mercaptocarboxylic acid | |
JPS55139375A (en) | Production of hydroxyflavan | |
JPS5764661A (en) | Preparation of mercaptoamines | |
JPS5721366A (en) | Production of 2-mercaptoethylamine hydrohalide | |
JPS5767555A (en) | Production of s-(aminoalkyl)thiosulfate salt | |
JPS56138151A (en) | Preparation of beta-chloroalanine | |
JPS5753458A (en) | Preparation of mercaptoamine | |
JPS568358A (en) | Production of cysteamine mineral acid salt | |
JPS5767588A (en) | Preparation of beta-carboxyethyl germanium sesquioxide | |
JPS5762251A (en) | Preparation of cysteamine and/or cystamine | |
JPS5626850A (en) | Preparation of 2-aminoacetal | |
JPS57203057A (en) | Preparation of 2-mercaptoethylamines | |
JPS57140760A (en) | Production of mercaptoamine | |
JPS5711960A (en) | Preparation of mercaptoamine | |
JPS5746948A (en) | Production of beta- 1,2,2,-trifluoro-2-alkoxyethyl alanine derivative | |
JPS57206636A (en) | Preparation of 3,3-dimethylbutyric acid | |
JPS5562050A (en) | Preparation of substituted phenylacetohydroxamic acid | |
JPS57209265A (en) | Preparation of di-lower alkyl ester of naphthalenedisulfonic acid | |
JPS577460A (en) | Production of oxime | |
JPS5781454A (en) | Preparation of cysteamine mineral acid salt | |
JPS5639053A (en) | Preparation of salt of mineral acid of alpha-halogeno- beta-alanine | |
JPS5724361A (en) | Preparation of indole derivative | |
JPS57203052A (en) | Preparation of cyanoacetaldehyde | |
JPS56156259A (en) | Preparation of high-purity tolyltioureas | |
JPS5772983A (en) | Preparation of 1,2,3,4,6,7,8,9-octahydrophenazine |