JPS5724361A - Preparation of indole derivative - Google Patents

Preparation of indole derivative

Info

Publication number
JPS5724361A
JPS5724361A JP9758880A JP9758880A JPS5724361A JP S5724361 A JPS5724361 A JP S5724361A JP 9758880 A JP9758880 A JP 9758880A JP 9758880 A JP9758880 A JP 9758880A JP S5724361 A JPS5724361 A JP S5724361A
Authority
JP
Japan
Prior art keywords
compound shown
formula
alkyl
reaction product
starting material
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9758880A
Other languages
Japanese (ja)
Inventor
Kiyonori Yokogoshi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PAAMAKEMU ASIA KK
Permachem Asia Ltd
Original Assignee
PAAMAKEMU ASIA KK
Permachem Asia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PAAMAKEMU ASIA KK, Permachem Asia Ltd filed Critical PAAMAKEMU ASIA KK
Priority to JP9758880A priority Critical patent/JPS5724361A/en
Publication of JPS5724361A publication Critical patent/JPS5724361A/en
Pending legal-status Critical Current

Links

Landscapes

  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Indole Compounds (AREA)

Abstract

PURPOSE: To obtain the titled substance useful as a remedy for arrhythmia, etc. in high yield by an easily handling method, by reacting an oxazolidinone derivative as a starting material with a compound, e.g., 1,1-dichlorotrimethylamine, etc., followed by reducing and hydrolyzing the reaction product.
CONSTITUTION: A compound shown by the formula I (R is alkyl) as a starting material is reacted with a compound shown by the formula II (R1 is alkyl, aryl, or aralkyl; X is halogen) is a solvent, e.g., dimethyl sulfoxide, etc. preferably at 50W 150°C. The reaction product is reduced with hydrogen in the presence of a basic substance, e.g., sodium hydroxide, etc. and a catalyst, preferably platinum, etc. and hydrolyzed, so that the oxazolidinone ring is subjected to ring closure and cleavage, to give a compound shown by the formula III.
COPYRIGHT: (C)1982,JPO&Japio
JP9758880A 1980-07-18 1980-07-18 Preparation of indole derivative Pending JPS5724361A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9758880A JPS5724361A (en) 1980-07-18 1980-07-18 Preparation of indole derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9758880A JPS5724361A (en) 1980-07-18 1980-07-18 Preparation of indole derivative

Publications (1)

Publication Number Publication Date
JPS5724361A true JPS5724361A (en) 1982-02-08

Family

ID=14196391

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9758880A Pending JPS5724361A (en) 1980-07-18 1980-07-18 Preparation of indole derivative

Country Status (1)

Country Link
JP (1) JPS5724361A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166280A (en) * 1989-05-08 1992-11-24 Sumitomo Chemical Company, Limited Olefin polymerization catalyst and process for producing ethylene copolymers
US8138284B2 (en) 2008-12-25 2012-03-20 Sumitomo Chemical Company, Limited Process for producing propylene block copolymer

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166280A (en) * 1989-05-08 1992-11-24 Sumitomo Chemical Company, Limited Olefin polymerization catalyst and process for producing ethylene copolymers
US8138284B2 (en) 2008-12-25 2012-03-20 Sumitomo Chemical Company, Limited Process for producing propylene block copolymer

Similar Documents

Publication Publication Date Title
IL71958A (en) Process for the preparation of phosphorus-containing cyanohydrin derivatives
JPS5724361A (en) Preparation of indole derivative
JPS57123181A (en) Preparation of pyrazolo (1,5-a) pyridine derivative
ES8307236A1 (en) Process for the preparation of a furan derivative.
JPS5721387A (en) Preparation of oxazolidinone derivative
JPS57126427A (en) Preparation of 1-substituted-azulene derivative
JPS5758645A (en) Preparation of carbonate
JPS5711938A (en) Preparation of 1,1-dialkoxy-3-alkynes
JPS5441869A (en) 1-methylsulfinyl-1-methylthio-2-(n-alkylpyrrolyl-2)- ethylene
JPS57169458A (en) Preparation of indole derivative
JPS57126488A (en) Preparation of chromone-2-carboxylate
JPS5732254A (en) Novel preparation of (s)-(-)-1-alkylamino-3-aryl- oxypropane-2-ol
JPS54138554A (en) Indole derivative
JPS5528925A (en) Dihydrouridylic acid derivative and its preparation
JPS5446779A (en) Preparation of 3-isoxazolylurea
JPS5653652A (en) Preparation of indole or indole derivative
JPS5711960A (en) Preparation of mercaptoamine
JPS55143962A (en) Novel aldehyde compound and its preparation
JPS5788157A (en) Preparation of aminoiminoacetic acid
JPS55164674A (en) Preparation of 4- 3-isopropylamino-2-hydroxy-propoxy indole
JPS5615265A (en) Preparation of indole derivative
JPS56127360A (en) Preparation of 4-benzoyl-5-hydroxypyrazole compound
JPS5764661A (en) Preparation of mercaptoamines
JPS5780367A (en) Preparation of tryptophan and its derivative
JPS5690036A (en) Cyclohexylidene acetic acid derivative and its preparation