JPS5528925A - Dihydrouridylic acid derivative and its preparation - Google Patents

Dihydrouridylic acid derivative and its preparation

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Publication number
JPS5528925A
JPS5528925A JP10154778A JP10154778A JPS5528925A JP S5528925 A JPS5528925 A JP S5528925A JP 10154778 A JP10154778 A JP 10154778A JP 10154778 A JP10154778 A JP 10154778A JP S5528925 A JPS5528925 A JP S5528925A
Authority
JP
Japan
Prior art keywords
acid
dihydrouridylic
acid derivative
formula
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10154778A
Other languages
Japanese (ja)
Inventor
Kazuo Sakuma
Yasushi Fukai
Shoichiro Ozaki
Yoshimasa Ike
Haruki Mori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanto Denka Kogyo Co Ltd
Mitsui Toatsu Chemicals Inc
Original Assignee
Kanto Denka Kogyo Co Ltd
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanto Denka Kogyo Co Ltd, Mitsui Toatsu Chemicals Inc filed Critical Kanto Denka Kogyo Co Ltd
Priority to JP10154778A priority Critical patent/JPS5528925A/en
Publication of JPS5528925A publication Critical patent/JPS5528925A/en
Pending legal-status Critical Current

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Abstract

NEW MATERIAL:A dihydrouridylic acid derivative of the formula, and its selt.
EXAMPLE: Monosodium salt of 5,6-dihydro-5-fluoro-6-hydroxyuridylic acid.
USE: Raw materials for a carcinastatic, 5-fluorowridylic acid.
PROCESS: Uridylic acid (U) or its salt is reacted with fluorine in the presence of water at 60°C or below, preferably about room temperature to give the objective compound of the formula. The fluorine gas is diluted with an inert gas and used in an amount of 1W5 moles per mole of U. The mild reaction conditions neither cause side reactions nor discoloration of products, nor require purification.
COPYRIGHT: (C)1980,JPO&Japio
JP10154778A 1978-08-21 1978-08-21 Dihydrouridylic acid derivative and its preparation Pending JPS5528925A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10154778A JPS5528925A (en) 1978-08-21 1978-08-21 Dihydrouridylic acid derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10154778A JPS5528925A (en) 1978-08-21 1978-08-21 Dihydrouridylic acid derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS5528925A true JPS5528925A (en) 1980-02-29

Family

ID=14303453

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10154778A Pending JPS5528925A (en) 1978-08-21 1978-08-21 Dihydrouridylic acid derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5528925A (en)

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