JPS54151495A - Nephelometric immuno-assay method - Google Patents
Nephelometric immuno-assay methodInfo
- Publication number
- JPS54151495A JPS54151495A JP5893378A JP5893378A JPS54151495A JP S54151495 A JPS54151495 A JP S54151495A JP 5893378 A JP5893378 A JP 5893378A JP 5893378 A JP5893378 A JP 5893378A JP S54151495 A JPS54151495 A JP S54151495A
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- degrees
- concentration
- angle
- nephelometric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
- G01N21/51—Scattering, i.e. diffuse reflection within a body or fluid inside a container, e.g. in an ampoule
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP53058933A JPS5925460B2 (ja) | 1978-05-19 | 1978-05-19 | ネフェロメトリック・イムノアッセイ法及び装置 |
DE2920276A DE2920276C2 (de) | 1978-05-19 | 1979-05-18 | Nephelometrisches Immunbestimmungsverfahren und Nephelometer zur Durchführung des Verfahrens |
US06/294,055 US4401387A (en) | 1978-05-19 | 1981-08-18 | Nephelometric immunoassay and nephelometer |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP53058933A JPS5925460B2 (ja) | 1978-05-19 | 1978-05-19 | ネフェロメトリック・イムノアッセイ法及び装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS54151495A true JPS54151495A (en) | 1979-11-28 |
JPS5925460B2 JPS5925460B2 (ja) | 1984-06-18 |
Family
ID=13098625
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP53058933A Expired JPS5925460B2 (ja) | 1978-05-19 | 1978-05-19 | ネフェロメトリック・イムノアッセイ法及び装置 |
Country Status (3)
Country | Link |
---|---|
US (1) | US4401387A (ja) |
JP (1) | JPS5925460B2 (ja) |
DE (1) | DE2920276C2 (ja) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58173465A (ja) * | 1982-04-05 | 1983-10-12 | Wako Pure Chem Ind Ltd | 抗原抗体反応の光学的測定方法 |
JPH02501880A (ja) * | 1986-12-19 | 1990-06-21 | アルカテル・エヌ・ブイ | パケットスイッチング回路網 |
EP0479345A2 (en) * | 1990-08-28 | 1992-04-08 | Akzo N.V. | Scattered light detection immunoassay |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57175957A (en) * | 1981-04-24 | 1982-10-29 | Chugai Pharmaceut Co Ltd | Measuring method and device for antigen- antibody reaction |
US4766083A (en) * | 1982-04-04 | 1988-08-23 | Wako Pure Chemical Industries, Ltd. | Method for the photometric determination of biological agglutination |
US4541719A (en) * | 1982-07-20 | 1985-09-17 | Wyatt Philip J | Method and apparatus for characterizing microparticles and measuring their response to their environment |
DE3228774A1 (de) * | 1982-08-02 | 1984-02-02 | Siemens AG, 1000 Berlin und 8000 München | Analytische bestimmung von organischen zusaetzen in galvanikbaedern |
US4621063A (en) * | 1982-10-12 | 1986-11-04 | The Center For Immunological Studies | Methods for the detection and quantitation of immunological substances |
DE3307627A1 (de) * | 1983-03-04 | 1984-09-06 | Merck Patent Gmbh, 6100 Darmstadt | Verfahren und vorrichtung zur bestimmung von truebungen in fluessigkeiten |
GB8526355D0 (en) * | 1985-10-25 | 1985-11-27 | Alta Diagnostic Machines Ltd | Determination of antibody content of blood |
US5082790A (en) * | 1985-12-23 | 1992-01-21 | Beckman Instruments, Inc. | Apparatus and method for dynamic blanking of non-specific light scattering during rate nephelometric reactions |
WO1987003966A1 (en) * | 1985-12-23 | 1987-07-02 | Beckman Instruments, Inc. | Automatic immunochemistry analyzing apparatus and method |
US4954435A (en) * | 1987-01-12 | 1990-09-04 | Becton, Dickinson And Company | Indirect colorimetric detection of an analyte in a sample using ratio of light signals |
US4988630A (en) * | 1987-04-27 | 1991-01-29 | Hoffmann-La Roche Inc. | Multiple beam laser instrument for measuring agglutination reactions |
US4810090A (en) * | 1987-08-24 | 1989-03-07 | Cobe Laboratories, Inc. | Method and apparatus for monitoring blood components |
DE3813718A1 (de) * | 1988-04-22 | 1989-11-02 | Max Planck Gesellschaft | Vielwinkel-lichtstreuung |
JP2641927B2 (ja) * | 1988-11-16 | 1997-08-20 | 興和株式会社 | 微粒子測定装置 |
JPH0823559B2 (ja) * | 1990-03-13 | 1996-03-06 | 三共株式会社 | 酵素免疫測定装置における検量線の設定方法 |
JP2626738B2 (ja) * | 1990-03-13 | 1997-07-02 | 三共株式会社 | 化学発光検出装置 |
US5701176A (en) * | 1995-07-28 | 1997-12-23 | Precision Detectors, Inc. | High temperature light scattering measurement device comprising a rigid extension tube |
US8703492B2 (en) | 2007-04-06 | 2014-04-22 | Qiagen Gaithersburg, Inc. | Open platform hybrid manual-automated sample processing system |
US8877507B2 (en) | 2007-04-06 | 2014-11-04 | Qiagen Gaithersburg, Inc. | Ensuring sample adequacy using turbidity light scattering techniques |
US8355132B2 (en) * | 2007-04-06 | 2013-01-15 | Qiagen Gaithersburg, Inc. | Sample adequacy measurement system having a plurality of sample tubes and using turbidity light scattering techniques |
JP5667989B2 (ja) * | 2009-12-04 | 2015-02-12 | 株式会社日立ハイテクノロジーズ | 血液凝固分析装置 |
JP5216051B2 (ja) * | 2010-06-23 | 2013-06-19 | 株式会社日立ハイテクノロジーズ | 自動分析装置および自動分析方法 |
JP5822534B2 (ja) * | 2011-05-13 | 2015-11-24 | 株式会社日立ハイテクノロジーズ | 自動分析装置 |
JP5948173B2 (ja) | 2012-07-20 | 2016-07-06 | 株式会社日立ハイテクノロジーズ | 自動分析装置及び自動分析方法 |
EP4271710A1 (en) | 2020-12-29 | 2023-11-08 | CeMM - Forschungszentrum für Molekulare Medizin GmbH | Anti-april antibodies and uses thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB869483A (en) * | 1958-06-28 | 1961-05-31 | Hellige & Co Gmbh F | Method and apparatus for detecting in vitro the presence of antibodies in a liquid |
US3714444A (en) * | 1970-07-16 | 1973-01-30 | Keene Corp | Suspended solids analyzer |
DE2528912A1 (de) * | 1975-06-28 | 1977-01-20 | Yamatake Honeywell Co Ltd | Vorrichtung zum messen der konzentration einer trueben loesung |
US4157871A (en) * | 1976-06-02 | 1979-06-12 | Beckman Instruments, Inc. | System for rate immunonephelometric analysis |
US4164558A (en) * | 1976-11-22 | 1979-08-14 | Massachusetts Institute Of Technology | Method for optimizing reagents for agglutination reactions |
US4268171A (en) * | 1977-07-18 | 1981-05-19 | Beckman Instruments, Inc. | Method determining concentration in rate nephelometric immunochemical analysis |
US4174952A (en) * | 1978-01-23 | 1979-11-20 | Massachusetts Institute Of Technology | Immunoassay by light scattering intensity anisotropy measurements |
-
1978
- 1978-05-19 JP JP53058933A patent/JPS5925460B2/ja not_active Expired
-
1979
- 1979-05-18 DE DE2920276A patent/DE2920276C2/de not_active Expired
-
1981
- 1981-08-18 US US06/294,055 patent/US4401387A/en not_active Expired - Lifetime
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58173465A (ja) * | 1982-04-05 | 1983-10-12 | Wako Pure Chem Ind Ltd | 抗原抗体反応の光学的測定方法 |
JPH042906B2 (ja) * | 1982-04-05 | 1992-01-21 | ||
JPH02501880A (ja) * | 1986-12-19 | 1990-06-21 | アルカテル・エヌ・ブイ | パケットスイッチング回路網 |
EP0479345A2 (en) * | 1990-08-28 | 1992-04-08 | Akzo N.V. | Scattered light detection immunoassay |
EP0479345A3 (en) * | 1990-08-28 | 1992-09-09 | Akzo N.V. | Scattered light detection immunoassay |
Also Published As
Publication number | Publication date |
---|---|
DE2920276C2 (de) | 1982-05-13 |
JPS5925460B2 (ja) | 1984-06-18 |
US4401387A (en) | 1983-08-30 |
DE2920276A1 (de) | 1979-11-22 |
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