GB869483A - Method and apparatus for detecting in vitro the presence of antibodies in a liquid - Google Patents

Method and apparatus for detecting in vitro the presence of antibodies in a liquid

Info

Publication number
GB869483A
GB869483A GB22198/59A GB2219859A GB869483A GB 869483 A GB869483 A GB 869483A GB 22198/59 A GB22198/59 A GB 22198/59A GB 2219859 A GB2219859 A GB 2219859A GB 869483 A GB869483 A GB 869483A
Authority
GB
United Kingdom
Prior art keywords
photo
cell
liquid
antibodies
light
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB22198/59A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fritz Hellige und Co GmbH
Original Assignee
Fritz Hellige und Co GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fritz Hellige und Co GmbH filed Critical Fritz Hellige und Co GmbH
Publication of GB869483A publication Critical patent/GB869483A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/82—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

869,483. Photo-electric measuring apparatus. HELLIGE & CO. G.m.b.H., FRITZ. June 29, 1959 [June 28, 1958], No. 22198/59. Class 40(3) In a method of detecting the presence of particles in a liquid a first liquid and a second liquid are brought together as superimposed layers and a light beam is passed first through one liquid and then through the other, the light dispersed from the particles being detected by a photo-cell. In the detection of antibodies the liquids are superimposed in a glass container f, the second liquid containing a known concentration of antigen, and the first an unknown concentration of antibodies. A light beam from a source a passes through the container and through a hole h in a photo-cell i when there is no antibody present, and hence no dispersion of light by aggregates. However, when aggregates are present dispersed light falls on the sensitive annular region of the photo-cell i. The output of the photo-cell is registered on meter M and by use of a calibration curve, Fig. 2 (not shown), the concentration of antibodies may be determined. A method of deriving this curve is given. The photo-cell receives light over a solid angle indicated by the lines n and this angle may be varied by providing the cell with an adjustable diaphragm.
GB22198/59A 1958-06-28 1959-06-29 Method and apparatus for detecting in vitro the presence of antibodies in a liquid Expired GB869483A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE869483X 1958-06-28

Publications (1)

Publication Number Publication Date
GB869483A true GB869483A (en) 1961-05-31

Family

ID=6802950

Family Applications (1)

Application Number Title Priority Date Filing Date
GB22198/59A Expired GB869483A (en) 1958-06-28 1959-06-29 Method and apparatus for detecting in vitro the presence of antibodies in a liquid

Country Status (1)

Country Link
GB (1) GB869483A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2905433A1 (en) * 1978-02-16 1979-08-30 Mitsubishi Chem Ind METHOD FOR DETERMINATION OF ANTIGEN AND ANTIBODIES
DE2920276A1 (en) * 1978-05-19 1979-11-22 Hitachi Ltd NEPHELOMETRIC IMMUNE DETERMINATION METHOD AND NEPHELOMETER
FR2553515A1 (en) * 1983-10-18 1985-04-19 Cottingham Hugh REAGENT DETECTION SYSTEM, SAMPLE CELL, AND KINETIC ACTIVATION SYSTEM FOR USE THEREOF

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2905433A1 (en) * 1978-02-16 1979-08-30 Mitsubishi Chem Ind METHOD FOR DETERMINATION OF ANTIGEN AND ANTIBODIES
DE2920276A1 (en) * 1978-05-19 1979-11-22 Hitachi Ltd NEPHELOMETRIC IMMUNE DETERMINATION METHOD AND NEPHELOMETER
FR2553515A1 (en) * 1983-10-18 1985-04-19 Cottingham Hugh REAGENT DETECTION SYSTEM, SAMPLE CELL, AND KINETIC ACTIVATION SYSTEM FOR USE THEREOF

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