JPS5224581A - Novel colorrproducing enzymatic substrate - Google Patents

Novel colorrproducing enzymatic substrate

Info

Publication number
JPS5224581A
JPS5224581A JP51082441A JP8244176A JPS5224581A JP S5224581 A JPS5224581 A JP S5224581A JP 51082441 A JP51082441 A JP 51082441A JP 8244176 A JP8244176 A JP 8244176A JP S5224581 A JPS5224581 A JP S5224581A
Authority
JP
Japan
Prior art keywords
colorrproducing
novel
enzymatic substrate
enzymatic
substrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP51082441A
Other languages
English (en)
Other versions
JPS5615238B2 (ja
Inventor
Tsuuresonaabueekensutamu Buu
Eriku Aureru Reifu
Giyoran Kureson Kaaru
Gunira Kaaruson Birugitsuta
Ingemaa Gusutafuson Suteigu
Anita Orauson Gun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phadia AB
Original Assignee
Kabi AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi AB filed Critical Kabi AB
Publication of JPS5224581A publication Critical patent/JPS5224581A/ja
Publication of JPS5615238B2 publication Critical patent/JPS5615238B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10—Anilides
    • C12Q2337/12—Para-Nitroanilides p-NA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP51082441A 1975-07-11 1976-07-10 Novel colorrproducing enzymatic substrate Granted JPS5224581A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7507974A SE407571B (sv) 1975-07-11 1975-07-11 Nya kromogena enzymsubstrat for serinproteaser

Publications (2)

Publication Number Publication Date
JPS5224581A true JPS5224581A (en) 1977-02-24
JPS5615238B2 JPS5615238B2 (ja) 1981-04-09

Family

ID=20325115

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51082441A Granted JPS5224581A (en) 1975-07-11 1976-07-10 Novel colorrproducing enzymatic substrate

Country Status (23)

Country Link
US (1) US4214049A (ja)
JP (1) JPS5224581A (ja)
AT (1) AT349648B (ja)
AU (1) AU497546B2 (ja)
BE (1) BE843969A (ja)
CA (1) CA1081212A (ja)
CH (1) CH622285A5 (ja)
CS (1) CS199631B2 (ja)
DD (1) DD127320A5 (ja)
DE (1) DE2629067A1 (ja)
DK (1) DK146937C (ja)
ES (1) ES449738A1 (ja)
FI (1) FI56524C (ja)
FR (1) FR2317278A1 (ja)
GB (1) GB1510925A (ja)
IL (1) IL49830A (ja)
IT (1) IT1062604B (ja)
NL (1) NL187693C (ja)
NO (1) NO142812C (ja)
PL (1) PL103098B1 (ja)
SE (1) SE407571B (ja)
SU (1) SU700060A3 (ja)
ZA (1) ZA763585B (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5537120A (en) * 1978-09-06 1980-03-15 Kanji Tsuchiya Method and device for preparation of food from oilseed
JPS57177985U (ja) * 1981-04-30 1982-11-11
JPS62294696A (ja) * 1980-05-06 1987-12-22 ペンタフアルム・アクチエンゲゼルシヤフト トリペプチド誘導体
JPH01112157A (ja) * 1987-07-10 1989-04-28 Yamanouchi Pharmaceut Co Ltd 組織プラスミノーゲンアクチベーター活性の測定法，測定具及び測定用キット
JPH0383093U (ja) * 1989-12-09 1991-08-23

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH634662A5 (de) * 1976-05-28 1983-02-15 Pentapharm Ag Verwendung von tripeptidderivaten zur quantitativen bestimmung von plasminogen-aktivatoren.
SE7801373L (sv) * 1978-02-07 1979-08-08 Kabi Ab Lett spjelkbara substrat for kvantifiering av proteaser
EP0009010B1 (en) * 1978-07-18 1983-03-02 Kabi AB Bradykinin inhibiting tripeptide derivatives, process for their preparation and pharmaceutical preparations containing them
US4275153A (en) * 1978-08-03 1981-06-23 American Hospital Supply Corporation Analytical fluorogenic substrates for proteolytic enzymes
JPS5559149A (en) * 1978-10-30 1980-05-02 Torii Yakuhin Kk Aminoacid derivative
JPS59499B2 (ja) * 1978-11-02 1984-01-07 味の素株式会社 ペプチド誘導体
US4327178A (en) 1979-05-01 1982-04-27 University Of Miami Urinary kallikrein assay: specific substrates and assay method
CA1161431A (en) * 1979-05-11 1984-01-31 Lars G. Svendsen Tripeptide derivatives
DE2936543A1 (de) * 1979-09-10 1981-04-09 Behringwerke Ag, 3550 Marburg Chromogene verbindungen
CA1161432A (en) * 1980-02-12 1984-01-31 Lars G. Svendsen Tripeptide derivatives and their application in assaying enzymes
DE3108322A1 (de) 1980-03-18 1981-12-24 Immuno Aktiengesellschaft für chemisch-medizinische Produkte, 1220 Wien Chromogenes enzymsubstrat
US4568636A (en) * 1981-03-25 1986-02-04 Pentapharm Ag Tripeptide derivatives
US4510241A (en) * 1981-09-03 1985-04-09 Mallinckrodt, Inc. Peptide-type substrates useful in the quantitative determination of endotoxin
US4406832A (en) * 1981-09-03 1983-09-27 Mallinckrodt, Inc. Peptide-type substrates useful in the quantitative determination of endotoxin
JPS5863399A (ja) * 1981-10-14 1983-04-15 Nitto Boseki Co Ltd 新規なプラスミン測定用基質
DE3268329D1 (en) * 1981-11-02 1986-02-13 Pentapharm Ag Process for the quantitative determination of the blood clotting factor xii in human plasma
US4448715A (en) * 1981-11-02 1984-05-15 University Of Miami Tagged pyroglu-L-Phe-L-Arg derivatives, substrates and assays for kallikrein
NL8201987A (nl) * 1982-05-13 1983-12-01 Tno Werkwijze voor het bepalen van de activiteit van plasminogeenactivator van het weefseltype, alsmede voor gebruik bij deze werkwijze geschikte combinatie van het "kit"-type.
DE3244030A1 (de) * 1982-11-27 1984-05-30 Behringwerke Ag, 3550 Marburg Chromogene verbindungen, verfahren zu ihrer herstellung und ihre verwendung
DK201084A (da) * 1983-04-28 1984-10-29 Kimberly Clark Co Fremgangsmaade til bestemmelse af cathepsin b i naervaerelse af andre proteolytiske enzymer, og forbindelser til anvendelse ved fremgangsmaaden
EP0182929A1 (de) * 1984-11-26 1986-06-04 American Hospital Supply Corporation Koaktivator zur Aktivierung von Protein C
DE3536903A1 (de) * 1985-10-16 1987-04-16 Boehringer Mannheim Gmbh Verfahren zur photometrischen bestimmung von protein c
JPS62126196A (ja) * 1985-11-26 1987-06-08 Nitto Boseki Co Ltd 新規なα１−アンチトリプシン測定用化合物
DE3710937A1 (de) * 1987-04-01 1988-10-13 Boehringer Mannheim Gmbh Chromogene verbindungen, ihre herstellung und verwendung als enzymsubstrate
EP0802986B1 (en) 1995-01-10 2001-09-19 Hendrik Coenraad Hemker Methods of determining endogenous thrombin potential (etp) and thrombin substrates for use in said methods
CN114341154B (zh) * 2019-09-05 2024-07-30 国立大学法人东京农工大学 类胰蛋白酶活性测定用底物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4949695A (ja) * 1972-05-02 1974-05-14

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE380258B (sv) * 1972-05-02 1975-11-03 Bofors Ab Nya diagnostiskt verksamma substrat med hog specificitet till trypsin och andra enzymer av typen peptidyl-peptid-hydrolaser
DE2527932C2 (de) * 1974-07-02 1983-04-21 Pentapharm AG, 4052 Basel Säureadditionssalze von Tripeptidderivaten und deren Verwendung als Substrate zur Bestimmung von Plasmakallikrein
SE407058B (sv) * 1974-12-05 1979-03-12 Kabi Ab Nya kromogena enzymsubstrat for serinproteaser
CH622286A5 (ja) * 1975-06-23 1981-03-31 Pentapharm Ag

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4949695A (ja) * 1972-05-02 1974-05-14

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5537120A (en) * 1978-09-06 1980-03-15 Kanji Tsuchiya Method and device for preparation of food from oilseed
JPS5644701B2 (ja) * 1978-09-06 1981-10-21
JPS62294696A (ja) * 1980-05-06 1987-12-22 ペンタフアルム・アクチエンゲゼルシヤフト トリペプチド誘導体
JPS62294695A (ja) * 1980-05-06 1987-12-22 ペンタフアルム・アクチエンゲゼルシヤフト トリペプチド誘導体
JPH0244839B2 (ja) * 1980-05-06 1990-10-05 Pentapharm Ag
JPH0244840B2 (ja) * 1980-05-06 1990-10-05 Pentapharm Ag
JPS57177985U (ja) * 1981-04-30 1982-11-11
JPH01112157A (ja) * 1987-07-10 1989-04-28 Yamanouchi Pharmaceut Co Ltd 組織プラスミノーゲンアクチベーター活性の測定法，測定具及び測定用キット
JPH0588783B2 (ja) * 1987-07-10 1993-12-24 Yamanouchi Pharma Co Ltd
JPH0383093U (ja) * 1989-12-09 1991-08-23

Also Published As

Publication number Publication date
CH622285A5 (ja) 1981-03-31
DK146937C (da) 1984-07-30
SE7507974L (sv) 1977-01-12
CA1081212A (en) 1980-07-08
DK312776A (da) 1977-01-12
ATA464076A (de) 1978-09-15
SE407571B (sv) 1979-04-02
DE2629067A1 (de) 1977-01-13
NL187693C (nl) 1991-12-16
FI56524B (fi) 1979-10-31
US4214049A (en) 1980-07-22
FR2317278A1 (fr) 1977-02-04
FI762009A (ja) 1977-01-12
IL49830A0 (en) 1976-08-31
NO142812B (no) 1980-07-14
AU497546B2 (en) 1978-12-14
AT349648B (de) 1979-04-10
DD127320A5 (ja) 1977-09-14
PL103098B1 (pl) 1979-05-31
IT1062604B (it) 1984-10-20
DK146937B (da) 1984-02-20
NL187693B (nl) 1991-07-16
CS199631B2 (en) 1980-07-31
ES449738A1 (es) 1977-12-16
JPS5615238B2 (ja) 1981-04-09
FI56524C (fi) 1980-02-11
IL49830A (en) 1978-12-17
ZA763585B (en) 1977-05-25
GB1510925A (en) 1978-05-17
NO142812C (no) 1980-10-22
SU700060A3 (ru) 1979-11-25
NL7607433A (nl) 1977-01-13
NO762406L (ja) 1977-01-12
FR2317278B1 (ja) 1981-01-30
BE843969A (fr) 1976-11-03
AU1530476A (en) 1978-01-05
DE2629067C2 (ja) 1989-08-03

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