JPS4852780A - - Google Patents

Info

Publication number
JPS4852780A
JPS4852780A JP47102799A JP10279972A JPS4852780A JP S4852780 A JPS4852780 A JP S4852780A JP 47102799 A JP47102799 A JP 47102799A JP 10279972 A JP10279972 A JP 10279972A JP S4852780 A JPS4852780 A JP S4852780A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP47102799A
Other languages
Japanese (ja)
Other versions
JPS5337870B2 (enrdf_load_stackoverflow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS4852780A publication Critical patent/JPS4852780A/ja
Publication of JPS5337870B2 publication Critical patent/JPS5337870B2/ja
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56One oxygen atom and one sulfur atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP10279972A 1971-10-29 1972-10-16 Expired JPS5337870B2 (enrdf_load_stackoverflow)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19400671A 1971-10-29 1971-10-29

Publications (2)

Publication Number Publication Date
JPS4852780A true JPS4852780A (enrdf_load_stackoverflow) 1973-07-24
JPS5337870B2 JPS5337870B2 (enrdf_load_stackoverflow) 1978-10-12

Family

ID=22715935

Family Applications (2)

Application Number Title Priority Date Filing Date
JP10279972A Expired JPS5337870B2 (enrdf_load_stackoverflow) 1971-10-29 1972-10-16
JP1336078A Granted JPS53116386A (en) 1971-10-29 1978-02-08 Method of producing novel hydroxypyrimidines

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP1336078A Granted JPS53116386A (en) 1971-10-29 1978-02-08 Method of producing novel hydroxypyrimidines

Country Status (25)

Country Link
JP (2) JPS5337870B2 (enrdf_load_stackoverflow)
AR (2) AR198798A1 (enrdf_load_stackoverflow)
AT (2) AT321308B (enrdf_load_stackoverflow)
AU (1) AU467600B2 (enrdf_load_stackoverflow)
BE (1) BE790125A (enrdf_load_stackoverflow)
CA (1) CA980778A (enrdf_load_stackoverflow)
CH (2) CH549579A (enrdf_load_stackoverflow)
DE (3) DE2248741C3 (enrdf_load_stackoverflow)
DK (1) DK131465B (enrdf_load_stackoverflow)
EG (1) EG11013A (enrdf_load_stackoverflow)
ES (2) ES407730A1 (enrdf_load_stackoverflow)
FI (1) FI55503C (enrdf_load_stackoverflow)
FR (1) FR2157865B1 (enrdf_load_stackoverflow)
GB (2) GB1377720A (enrdf_load_stackoverflow)
IE (1) IE37043B1 (enrdf_load_stackoverflow)
IL (2) IL40458A (enrdf_load_stackoverflow)
LU (1) LU66304A1 (enrdf_load_stackoverflow)
NL (1) NL166470C (enrdf_load_stackoverflow)
NO (1) NO136574C (enrdf_load_stackoverflow)
PH (2) PH10129A (enrdf_load_stackoverflow)
PL (2) PL89852B1 (enrdf_load_stackoverflow)
SE (2) SE393376B (enrdf_load_stackoverflow)
SU (2) SU498908A3 (enrdf_load_stackoverflow)
YU (2) YU35125B (enrdf_load_stackoverflow)
ZA (1) ZA727362B (enrdf_load_stackoverflow)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS597174A (ja) * 1982-06-18 1984-01-14 バイヤ−スドルフ・アクチエンゲゼルシヤフト 置換された5−フエニルチオ−6−アミノ−ピリミジノン、その製造方法及びその利用ならびにこの化合物を含む調剤
JP2009506043A (ja) * 2005-08-22 2009-02-12 メリオール・ディスカヴァリー・インコーポレイテッド Lynキナーゼの活性を調節し、関連する疾患を治療するための方法および製剤

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151912U (enrdf_load_stackoverflow) * 1979-04-17 1980-11-01
JPH0655686B2 (ja) * 1988-08-30 1994-07-27 宇部興産株式会社 p−ブロモフェノキシアセトアルデヒドジアルキルアセタール類の製造方法
US8552184B2 (en) 2008-07-03 2013-10-08 Melior Pharmaceuticals I, Inc. Compounds and methods for treating disorders related to glucose metabolism
US20130158055A1 (en) 2010-05-28 2013-06-20 Andrew G. Reaume Prevention Of Pancreatic Beta Cell Degeneration
JP7182605B2 (ja) 2017-04-10 2022-12-02 メリオール・ファーマスーティカルズ・ワン・インコーポレイテッド lynキナーゼ活性化因子及びTRPM8アゴニストを含む組成物及び医薬の製造におけるそれらの使用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2913462A (en) * 1959-11-17 Eahl h
GB951431A (en) * 1959-03-17 1964-03-04 Wellcome Found Pyrimidine derivatives and the manufacture thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS597174A (ja) * 1982-06-18 1984-01-14 バイヤ−スドルフ・アクチエンゲゼルシヤフト 置換された5−フエニルチオ−6−アミノ−ピリミジノン、その製造方法及びその利用ならびにこの化合物を含む調剤
JP2009506043A (ja) * 2005-08-22 2009-02-12 メリオール・ディスカヴァリー・インコーポレイテッド Lynキナーゼの活性を調節し、関連する疾患を治療するための方法および製剤

Also Published As

Publication number Publication date
AT321308B (de) 1975-03-25
DE2264374B2 (de) 1980-08-07
NL166470B (nl) 1981-03-16
DE2264374A1 (de) 1973-05-24
CH549579A (fr) 1974-05-31
AT320656B (de) 1975-02-25
AR198798A1 (es) 1974-07-24
CA980778A (en) 1975-12-30
IE37043B1 (en) 1977-04-27
DE2264374C3 (de) 1981-07-23
SE397090B (sv) 1977-10-17
SU498908A3 (ru) 1976-01-05
DE2264657C2 (de) 1982-09-16
DE2264657A1 (de) 1974-06-20
SE7505279L (sv) 1975-05-06
ES407730A1 (es) 1976-01-16
IL48790A0 (en) 1976-03-31
JPS5337870B2 (enrdf_load_stackoverflow) 1978-10-12
SU505362A3 (ru) 1976-02-28
YU255172A (en) 1980-03-15
DK131465B (da) 1975-07-21
BE790125A (fr) 1973-04-16
IL40458A0 (en) 1972-11-28
DK131465C (enrdf_load_stackoverflow) 1975-12-08
AR196263A1 (es) 1973-12-10
NL166470C (nl) 1981-08-17
IL48790A (en) 1976-05-31
ES436624A1 (es) 1977-02-01
DE2248741B2 (de) 1974-11-14
PH11594A (en) 1978-03-31
ZA727362B (en) 1973-11-28
AU467600B2 (en) 1975-12-04
CH555832A (fr) 1974-11-15
LU66304A1 (enrdf_load_stackoverflow) 1973-05-03
YU36295B (en) 1982-06-18
FI55503B (fi) 1979-04-30
DE2248741C3 (de) 1975-06-26
SE393376B (sv) 1977-05-09
YU99179A (en) 1981-08-31
EG11013A (en) 1976-11-30
PH10129A (en) 1976-09-02
NL7213959A (enrdf_load_stackoverflow) 1973-05-02
PL89852B1 (enrdf_load_stackoverflow) 1976-12-31
GB1377308A (en) 1974-12-11
IE37043L (en) 1973-04-29
AU4722872A (en) 1974-04-04
FI55503C (fi) 1979-08-10
YU35125B (en) 1980-09-25
JPS5422995B2 (enrdf_load_stackoverflow) 1979-08-10
PL84634B1 (enrdf_load_stackoverflow) 1976-04-30
GB1377720A (en) 1974-12-18
JPS53116386A (en) 1978-10-11
DE2248741A1 (de) 1973-05-03
IL40458A (en) 1976-05-31
NO136574B (enrdf_load_stackoverflow) 1977-06-20
FR2157865B1 (enrdf_load_stackoverflow) 1975-10-31
FR2157865A1 (enrdf_load_stackoverflow) 1973-06-08
NO136574C (no) 1977-09-28

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