CH549579A - Procede pour la preparation de nouvelles hydroxy-pyrimidines. - Google Patents

Procede pour la preparation de nouvelles hydroxy-pyrimidines.

Info

Publication number
CH549579A
CH549579A CH165674A CH165674A CH549579A CH 549579 A CH549579 A CH 549579A CH 165674 A CH165674 A CH 165674A CH 165674 A CH165674 A CH 165674A CH 549579 A CH549579 A CH 549579A
Authority
CH
Switzerland
Prior art keywords
pyrimidines
preparation
new hydroxy
hydroxy
new
Prior art date
Application number
CH165674A
Other languages
English (en)
French (fr)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CH549579A publication Critical patent/CH549579A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56One oxygen atom and one sulfur atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH165674A 1971-10-29 1972-10-16 Procede pour la preparation de nouvelles hydroxy-pyrimidines. CH549579A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19400671A 1971-10-29 1971-10-29

Publications (1)

Publication Number Publication Date
CH549579A true CH549579A (fr) 1974-05-31

Family

ID=22715935

Family Applications (2)

Application Number Title Priority Date Filing Date
CH165674A CH549579A (fr) 1971-10-29 1972-10-16 Procede pour la preparation de nouvelles hydroxy-pyrimidines.
CH1507872A CH555832A (fr) 1971-10-29 1972-10-16 Procede pour la preparation de nouvelles pyrimidinones.

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH1507872A CH555832A (fr) 1971-10-29 1972-10-16 Procede pour la preparation de nouvelles pyrimidinones.

Country Status (25)

Country Link
JP (2) JPS5337870B2 (enrdf_load_stackoverflow)
AR (2) AR198798A1 (enrdf_load_stackoverflow)
AT (2) AT321308B (enrdf_load_stackoverflow)
AU (1) AU467600B2 (enrdf_load_stackoverflow)
BE (1) BE790125A (enrdf_load_stackoverflow)
CA (1) CA980778A (enrdf_load_stackoverflow)
CH (2) CH549579A (enrdf_load_stackoverflow)
DE (3) DE2264657C2 (enrdf_load_stackoverflow)
DK (1) DK131465B (enrdf_load_stackoverflow)
EG (1) EG11013A (enrdf_load_stackoverflow)
ES (2) ES407730A1 (enrdf_load_stackoverflow)
FI (1) FI55503C (enrdf_load_stackoverflow)
FR (1) FR2157865B1 (enrdf_load_stackoverflow)
GB (2) GB1377308A (enrdf_load_stackoverflow)
IE (1) IE37043B1 (enrdf_load_stackoverflow)
IL (2) IL40458A (enrdf_load_stackoverflow)
LU (1) LU66304A1 (enrdf_load_stackoverflow)
NL (1) NL166470C (enrdf_load_stackoverflow)
NO (1) NO136574C (enrdf_load_stackoverflow)
PH (2) PH10129A (enrdf_load_stackoverflow)
PL (2) PL84634B1 (enrdf_load_stackoverflow)
SE (2) SE393376B (enrdf_load_stackoverflow)
SU (2) SU498908A3 (enrdf_load_stackoverflow)
YU (2) YU35125B (enrdf_load_stackoverflow)
ZA (1) ZA727362B (enrdf_load_stackoverflow)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151912U (enrdf_load_stackoverflow) * 1979-04-17 1980-11-01
DE3222914A1 (de) * 1982-06-18 1983-12-22 Beiersdorf Ag, 2000 Hamburg Substituierte 5-phenylthio-6-amino-pyrimidinone, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
JPH0655686B2 (ja) * 1988-08-30 1994-07-27 宇部興産株式会社 p−ブロモフェノキシアセトアルデヒドジアルキルアセタール類の製造方法
JP5113752B2 (ja) 2005-08-22 2013-01-09 メリオール・ファーマスーティカルズ・ワン・インコーポレイテッド Lynキナーゼの活性を調節し、関連する疾患を治療するための方法および製剤
US8552184B2 (en) 2008-07-03 2013-10-08 Melior Pharmaceuticals I, Inc. Compounds and methods for treating disorders related to glucose metabolism
WO2011150300A1 (en) 2010-05-28 2011-12-01 Melior Pharmaceuticals I, Inc. Prevention of pancreatic beta cell degeneration
SG11201909406VA (en) 2017-04-10 2019-11-28 Melior Pharmaceuticals I Inc Treatment of adipocytes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2913462A (en) * 1959-11-17 Eahl h
GB951431A (en) * 1959-03-17 1964-03-04 Wellcome Found Pyrimidine derivatives and the manufacture thereof

Also Published As

Publication number Publication date
AU467600B2 (en) 1975-12-04
FR2157865B1 (enrdf_load_stackoverflow) 1975-10-31
ZA727362B (en) 1973-11-28
AR198798A1 (es) 1974-07-24
GB1377720A (en) 1974-12-18
SE7505279L (sv) 1975-05-06
JPS4852780A (enrdf_load_stackoverflow) 1973-07-24
FR2157865A1 (enrdf_load_stackoverflow) 1973-06-08
SE397090B (sv) 1977-10-17
DE2248741C3 (de) 1975-06-26
YU255172A (en) 1980-03-15
NO136574C (no) 1977-09-28
ES407730A1 (es) 1976-01-16
FI55503C (fi) 1979-08-10
SU505362A3 (ru) 1976-02-28
NL7213959A (enrdf_load_stackoverflow) 1973-05-02
IE37043B1 (en) 1977-04-27
IL40458A (en) 1976-05-31
IL40458A0 (en) 1972-11-28
NL166470C (nl) 1981-08-17
CA980778A (en) 1975-12-30
DK131465C (enrdf_load_stackoverflow) 1975-12-08
JPS5337870B2 (enrdf_load_stackoverflow) 1978-10-12
JPS5422995B2 (enrdf_load_stackoverflow) 1979-08-10
BE790125A (fr) 1973-04-16
DE2248741A1 (de) 1973-05-03
DE2264374B2 (de) 1980-08-07
CH555832A (fr) 1974-11-15
DE2248741B2 (de) 1974-11-14
JPS53116386A (en) 1978-10-11
PH11594A (en) 1978-03-31
GB1377308A (en) 1974-12-11
DE2264657A1 (de) 1974-06-20
NL166470B (nl) 1981-03-16
NO136574B (enrdf_load_stackoverflow) 1977-06-20
IL48790A (en) 1976-05-31
FI55503B (fi) 1979-04-30
PH10129A (en) 1976-09-02
DE2264374C3 (de) 1981-07-23
DK131465B (da) 1975-07-21
YU99179A (en) 1981-08-31
IE37043L (en) 1973-04-29
EG11013A (en) 1976-11-30
YU35125B (en) 1980-09-25
DE2264374A1 (de) 1973-05-24
LU66304A1 (enrdf_load_stackoverflow) 1973-05-03
ES436624A1 (es) 1977-02-01
SE393376B (sv) 1977-05-09
YU36295B (en) 1982-06-18
DE2264657C2 (de) 1982-09-16
PL89852B1 (enrdf_load_stackoverflow) 1976-12-31
AU4722872A (en) 1974-04-04
AT320656B (de) 1975-02-25
AT321308B (de) 1975-03-25
AR196263A1 (es) 1973-12-10
IL48790A0 (en) 1976-03-31
SU498908A3 (ru) 1976-01-05
PL84634B1 (enrdf_load_stackoverflow) 1976-04-30

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Legal Events

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PL Patent ceased