JPH11505855A - 抗菌剤としてのn−オキシド - Google Patents
抗菌剤としてのn−オキシドInfo
- Publication number
- JPH11505855A JPH11505855A JP8536147A JP53614796A JPH11505855A JP H11505855 A JPH11505855 A JP H11505855A JP 8536147 A JP8536147 A JP 8536147A JP 53614796 A JP53614796 A JP 53614796A JP H11505855 A JPH11505855 A JP H11505855A
- Authority
- JP
- Japan
- Prior art keywords
- hydrogen
- alkyl
- methyl
- formula
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.式(I)または(II) 式中、Xは水素、ハロゲン、C1 〜4−アルキル、C1 〜4−アルコキシ、NH2 を表し、 Zは=CH−または=N−を表し、 Yは構造式 の基を表し、ここに R4は随時ヒドロキシルまたはメトキシで置換されていてもよい直鎖状もし くは分枝鎖状のC1〜C4−アルキル、シクロプロピル、炭素原子1〜3個を有す るアシルを表し、 R5は水素、メチル、フェニル、チエニルまたはピリジルを表し、 R6は水素またはC1 〜4−アルキルを表し、 R7は水素またはC1 〜4−アルキルを表し、 R8は水素またはC1 〜4−アルキルを表し、そして R1は炭素原子1〜3個を有するアルキル基、シクロプロピル、2−フルオ ロエチル、メトキシ、4−フルオロフェニル、2,4−ジフルオロフェニルまた はメチルアミノを表し、 R2は水素または随時メトキシもしくは2−メトキシエトキシで置換されて いてもよい炭素原子1〜6個を有するアルキル、及びシクロヘキシル、ベンジル 、2−オキソプロピル、フェナシル、エトキシカルボニルメチル、ピバロイルオ キシメチルを表し、 R3は水素、メチルまたはエチルを表し、 Aは窒素または=CH−、=C(ハロゲン)−、=C(OCH3)−、=C (CH3)−を表し、そして Bは酸素、随時メチルもしくはフェニルで置換されていてもよい=N−、ま たは=CH2を表す、 のキノロン−またはナフチリドンカルボン酸で置換される飽和の含窒素複素環の N−オキシド並びにその製薬学的に利用し得る水和物、酸付加塩及び塩基との塩 をベースとする抗菌性組成物。 2.式(I)または(II) 式中、Xは水素、ハロゲン、C1 〜4−アルキル、C1 〜4−アルコキシ、NH2 を表し、 Zは=CH−または=N−を表し、 Yは構造式 の基を表し、ここに R4は随時ヒドロキシルまたはメトキシで置換されていてもよい直鎖状もし くは分枝鎖状のC1〜C4−アルキル、シクロプロピル、炭素原子1〜3個を有す るアシルを表し、 R5は水素、メチル、フェニル、チエニルまたはピリジルを表し、 R6は水素またはC1 〜4−アルキルを表し、 R7は水素またはC1 〜4−アルキルを表し、 R8は水素またはC1 〜4−アルキルを表し、そして R1は炭素原子1〜3個を有するアルキル基、シクロプロピル、2−フルオ ロエチル、メトキシ、4−フルオロフェニル、2,4−ジフルオロフェニルまた はメチルアミノを表し、 R2は水素または随時メトキシもしくは2−メトキシエトキシで置 換されていてもよい炭素原子1〜6個を有するアルキル、及びシクロヘキシル、 ベンジル、2−オキソプロピル、フェナシル、エトキシカルボニルメチル、ピバ ロイルオキシメチルを表し、 R3は水素、メチルまたはエチルを表し、 Aは窒素または=CH−、=C(ハロゲン)−、=C(OCH3)−、=C (CH3)−を表し、そして Bは酸素、随時メチルもしくはフェニルで置換されていてもよい=N−、ま たは=CH2を表す、 のキノロン−またはナフチリドンカルボン酸で置換される飽和の含窒素複素環の N−オキシド並びにその製薬学的に利用し得る水和物、酸付加塩及び塩基との塩 をベースとする、動物の飼料及び飲料水を介して投与し得る組成物。 3.式(Ia) 式中、Yは構造式 の基を表し、ここに R4は随時ヒドロキシルまたはメトキシで置換されていてもよい直 鎖状もしくは分枝鎖状のC1〜C4−アルキル、シクロプロピル、炭素原子1〜3 個を有するアシルを表し、 R5は水素、メチル、フェニル、チエニルまたはピリジルを表し、 R6は水素またはC1 〜4−アルキルを表し、 R7は水素またはC1 〜4−アルキルを表し、 R8は水素またはC1 〜4−アルキルを表し、そして R2は水素または随時メトキシで置換されていてもよい炭素原子1〜4個を 有するアルキル、並びにベンジル、2−オキソプロピル、フェナシル及びまたエ トキシカルボニルメチルを表し、 Aは=N−、=CH−、=C(ハロゲン)−または=C(OCH3)−を表 す、 の、キノロンカルボン酸で置換される飽和の含窒素複素環の新規なN−オキシド 並びにその製薬学的に利用し得る水和物または酸付加塩もしくは塩基との塩。 4.a)対応する化合物(III) 式中、Y’はN−オキシド基Zのベースとなる飽和の含窒素複素環を表し、 A及びR1は請求の範囲第3項記載の意味を有する、 を酸素供与剤と反応させるか、或いは b)式(IV) 式中、A、R1、R2は請求の範囲第3項記載の意味を有し、そして Xはハロゲン、好ましくはフッ素または塩素を表す、 の化合物を適当ならば酸結合剤の存在下で式(V) Y−H (V) 式中、Yは上記の意味を有する、 の飽和の含窒素複素環のN−オキシドと反応させることを特徴とする、請求の範 囲第3項記載の式(Ia)の化合物の製造方法。 5.Aが=CH−を表し、 R1がシクロプロピルを表し、 R2が水素、メチルまたはエチルを表し、 Yが構造式 式中、R4は随時ヒドロキシルで置換されていてもよいメチル、エチルを表 し、 R5は水素またはメチルを表し、 R7は水素またはメチルを表す、 の基を表す、請求の範囲第1項記載の式(I)の化合物並びにその製薬 学的に利用し得る水和物及び酸付加塩、並びにこれらのものをベースとするカル ボン酸のアルカリ金属、アルカリ土金属、銀及びグアジニウム塩。 6.Aが=CH−を表し、 R1がシクロプロピルを表し、 R2が水素、メチルまたはエチルを表し、 Yが構造式 式中、R4は随時ヒドロキシルで置換されていてもよいメチル、エチルを表 し、 R5は水素またはメチルを表し、 R7は水素またはメチルを表す、 の基を表す、請求の範囲第1項記載の式(I)の化合物並びにその製薬学的に利 用し得る水和物及び酸付加塩、並びにこれらのものをベースとするカルボン酸の アルカリ金属、アルカリ土金属、銀及びグアジニウム塩。 7.活性化合物エンロフロキサシン、マルボフロキサシンまたはオフロキサシン の4−ピペラジニルN−オキシド。 8.動物の飲料水または飼料を介して経口的に投与し得る、バクテリア性疾病に 対する組成物を製造するための、請求の範囲第1項記載の式(I)または(II )の化合物の使用。 9.動物の飼料を介して経口的に投与し得る、バクテリア性疾病に対する組成物 を製造するための、請求の範囲第1項記載の式(I)または(II)の化合物の 使用。 10.飼料または飲料水を介する投与による動物のバクテリア性疾病の防除のた めの、請求の範囲第1項記載の式(I)または(II)の化合物の使用。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19519822A DE19519822A1 (de) | 1995-05-31 | 1995-05-31 | Neue antibakterielle Mittel |
DE19519822.0 | 1995-05-31 | ||
PCT/EP1996/002171 WO1996038417A1 (de) | 1995-05-31 | 1996-05-20 | N-oxide als antibakterielle mittel |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH11505855A true JPH11505855A (ja) | 1999-05-25 |
JP3868492B2 JP3868492B2 (ja) | 2007-01-17 |
Family
ID=7763230
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP53614796A Expired - Fee Related JP3868492B2 (ja) | 1995-05-31 | 1996-05-20 | 抗菌剤としてのn−オキシド |
Country Status (23)
Country | Link |
---|---|
US (1) | US6114351A (ja) |
EP (1) | EP0828715B1 (ja) |
JP (1) | JP3868492B2 (ja) |
KR (1) | KR100682746B1 (ja) |
CN (1) | CN1214009C (ja) |
AR (2) | AR003420A1 (ja) |
AT (1) | ATE204256T1 (ja) |
AU (1) | AU707628B2 (ja) |
BR (1) | BR9608593A (ja) |
CA (1) | CA2222552C (ja) |
CZ (1) | CZ290675B6 (ja) |
DE (2) | DE19519822A1 (ja) |
DK (1) | DK0828715T3 (ja) |
ES (1) | ES2161361T3 (ja) |
GR (1) | GR3037063T3 (ja) |
HU (1) | HUP9802076A3 (ja) |
NO (1) | NO319510B1 (ja) |
NZ (1) | NZ309074A (ja) |
PL (1) | PL187322B1 (ja) |
SK (1) | SK283994B6 (ja) |
TW (1) | TW442290B (ja) |
WO (1) | WO1996038417A1 (ja) |
ZA (1) | ZA964414B (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009523840A (ja) * | 2006-01-24 | 2009-06-25 | ソシエテ アノニム ベトキノル | ピリド(3,2,1−ij)−ベンズオキサジアジン型の化合物を含む、抗感染剤溶液 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9904108D0 (sv) | 1999-11-15 | 1999-11-15 | New Pharma Research Ab | Nya föreningar |
WO2006024253A1 (de) | 2004-09-03 | 2006-03-09 | Weinmann Geräte für Medizin GmbH & Co. KG | Kunststoffe für medizintechnische geräte |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5777683A (en) * | 1980-09-03 | 1982-05-15 | Bayer Ag | 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro- naphthyridine-3-carboxylic acids or salts thereof, manufacture and antibacterial thereof as active ingredient |
EP0090424A1 (en) * | 1982-03-31 | 1983-10-05 | Sterling Drug Inc. | New quinolone compounds and preparation thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5152984A (en) * | 1990-11-20 | 1992-10-06 | Dow Corning Corporation | Hair fixatives |
-
1995
- 1995-05-31 DE DE19519822A patent/DE19519822A1/de not_active Withdrawn
-
1996
- 1996-04-30 TW TW085105109A patent/TW442290B/zh not_active IP Right Cessation
- 1996-05-20 NZ NZ309074A patent/NZ309074A/xx not_active IP Right Cessation
- 1996-05-20 KR KR1019970708523A patent/KR100682746B1/ko not_active IP Right Cessation
- 1996-05-20 CZ CZ19973748A patent/CZ290675B6/cs not_active IP Right Cessation
- 1996-05-20 WO PCT/EP1996/002171 patent/WO1996038417A1/de not_active Application Discontinuation
- 1996-05-20 AU AU59005/96A patent/AU707628B2/en not_active Ceased
- 1996-05-20 CA CA002222552A patent/CA2222552C/en not_active Expired - Fee Related
- 1996-05-20 BR BR9608593A patent/BR9608593A/pt not_active Application Discontinuation
- 1996-05-20 SK SK1603-97A patent/SK283994B6/sk not_active IP Right Cessation
- 1996-05-20 EP EP96916138A patent/EP0828715B1/de not_active Expired - Lifetime
- 1996-05-20 JP JP53614796A patent/JP3868492B2/ja not_active Expired - Fee Related
- 1996-05-20 US US08/952,762 patent/US6114351A/en not_active Expired - Lifetime
- 1996-05-20 AT AT96916138T patent/ATE204256T1/de not_active IP Right Cessation
- 1996-05-20 ES ES96916138T patent/ES2161361T3/es not_active Expired - Lifetime
- 1996-05-20 CN CNB961956151A patent/CN1214009C/zh not_active Expired - Fee Related
- 1996-05-20 DK DK96916138T patent/DK0828715T3/da active
- 1996-05-20 HU HU9802076A patent/HUP9802076A3/hu unknown
- 1996-05-20 DE DE59607503T patent/DE59607503D1/de not_active Expired - Lifetime
- 1996-05-20 PL PL96323622A patent/PL187322B1/pl not_active IP Right Cessation
- 1996-05-24 AR ARP960102727A patent/AR003420A1/es unknown
- 1996-05-30 ZA ZA964414A patent/ZA964414B/xx unknown
-
1997
- 1997-11-27 NO NO19975464A patent/NO319510B1/no not_active IP Right Cessation
-
2001
- 2001-10-30 GR GR20010401935T patent/GR3037063T3/el unknown
-
2002
- 2002-06-10 AR ARP020102179A patent/AR034452A2/es active IP Right Grant
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5777683A (en) * | 1980-09-03 | 1982-05-15 | Bayer Ag | 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro- naphthyridine-3-carboxylic acids or salts thereof, manufacture and antibacterial thereof as active ingredient |
EP0090424A1 (en) * | 1982-03-31 | 1983-10-05 | Sterling Drug Inc. | New quinolone compounds and preparation thereof |
Non-Patent Citations (6)
Title |
---|
DOLORES CID, ET AL.: "In Vitro Activities of Enoxacin, Enfroxacin, Sparfloxacin,and Ciprofloxacin against Eschrichia coli", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 38, no. 10, JPNX006045089, 1994, pages 2469 - 2470, ISSN: 0000776907 * |
G. RICHARD, ET AL.: "High-performance Liquid Chromatographic Procedures for the Determination of Difloxacin and its Metab", J. CHROMATOGRAPHY, vol. 413 , JPNX006045088, 1987, pages 199 - 206, ISSN: 0000776906 * |
J.SCHRENZEL, ET AL.: "Influence of Rifampin on Fleloxacin Pharmacokinetics", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 37 No.10, JPNX006045086, 1993, pages 2132 - 2138, ISSN: 0000776904 * |
MARK P. ET AL.: "Novel Amino-Substituted 3-Quinolinecarboxylic Acid Antibacterial Agents:Synthesis and Structure-Acti", J. MED. CHEM., vol. 27, JPNX006045085, 1984, pages 1103 - 1108, XP002012275, ISSN: 0000776903, DOI: 10.1021/jm00375a003 * |
R.NAU, ET AL.: "Kinetics of Ofloxacin and Its Metabolites in Cerebrospinal Fluid after a Single Intravenous Infusion", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 38 No.3, JPNX006045084, 1994, pages 1849 - 1853, ISSN: 0000776902 * |
ULRICH JAEHDE, ET AL.: "Effect of an Antacid Containing Magnesium and Alminium on Absorption,Metabolism,and Mechanism of Ren", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 38, no. 5, JPNX006045087, 1994, pages 1129 - 1133, ISSN: 0000776905 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009523840A (ja) * | 2006-01-24 | 2009-06-25 | ソシエテ アノニム ベトキノル | ピリド(3,2,1−ij)−ベンズオキサジアジン型の化合物を含む、抗感染剤溶液 |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR0156238B1 (ko) | 7-(1-피롤리디닐)-3-퀴놀론-및 -나프티리돈카르복실산 유도체, 그의 제조 방법, 및 그의 제조를 위한 중간 생성물인 치환된 모노-및 비시클릭 피롤리딘 유도체, 및 이를 함유하는 항균제 및 사료 첨가제 | |
JP3046035B2 (ja) | 5―アルキルキノロンカルボン酸類 | |
AU715341B2 (en) | Possibly substituted 8-cyano-1-cyclopropyl-7-(2,8- diazabicyclo-(4.3.0)-nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo- 3-quinolin carboxylic acids and their derivatives | |
CS235502B2 (en) | Method of 1-ethyl or vinyl-6-halogen-1-4-dihydro-4-oxo-7- (1-piperazinyl)-1,8-naphtyridin-3-carboxyl acid production | |
NO881121L (no) | 5-substituerte kinolon- og naftyridonkarboksylsyrederivater. | |
DE19652239A1 (de) | Verwendung von 7-(2-Oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-chinolon- und -naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen | |
NZ203621A (en) | 4-quinolone-3-carboxylic acid derivatives | |
KR20210046015A (ko) | 염증성 장 질환의 치료를 위한 신규 의약 | |
US7176313B2 (en) | Anti acid-fast bacterial agent containing pyridonecarboxylic acids as active ingredient | |
JP3868492B2 (ja) | 抗菌剤としてのn−オキシド | |
JP3477466B2 (ja) | キノリンカルボン酸誘導体又はその塩 | |
CA1262350A (en) | Embonates of quinolonecarboxylic acids and of their derivatives | |
SU1029829A3 (ru) | Способ получени производных 1,8-нафтиридина или их фармацевтически пригодных солей | |
JP2000501110A (ja) | ピリド(3,2,1―ij)―1,3,4―ベンゾオキサジアジン | |
JPH0853460A (ja) | 8−アミノ−ピリド[1,2,3−d,e][1,3,4]ベンズオキサジアジン誘導体 | |
JPH0873468A (ja) | 8−アミノ−10−(アザビシクロアルキル)−ピリド[1,2,3−d,e][1,3,4]ベンズオキサジアジン誘導体 | |
JPH03209368A (ja) | 7―(置換)シクロアルキルアミノ―1―(置換)―6―フルオロ―1,4―ジヒドロ―4―オキソ―3―キノリンカルボン酸類 | |
TWI313602B (en) | Gyrase inhibitors and uses thereof | |
JPH10505345A (ja) | 新規チアゾロ[3,2−a]キノリンおよびチアゾロ[3,2−a]ナフチリジン誘導体 | |
WO1991016311A1 (en) | 7-(substituted hydrazino)-4-oxoquinoline-3-carboxylic acid derivative, its salt and its ester | |
JPH0841073A (ja) | 1,9−架橋チアゾロ[3,2−a]キノリン誘導体 | |
JPH0250108B2 (ja) | ||
IE19970856A1 (en) | 7-(1-Pyrrolidinyl)-3-quinolone and naphthyridone carboxylic acid derivatives, method for their preparation and for substituted mono- and bicyclic pyrrolidine intermediates, and their antibacterial and feed additive compositions | |
JPH0427235B2 (ja) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20041019 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20050119 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20050307 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20050415 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20050614 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20050908 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20060221 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20060519 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20060703 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20060817 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20061003 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20061011 |
|
R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20091020 Year of fee payment: 3 |
|
R360 | Written notification for declining of transfer of rights |
Free format text: JAPANESE INTERMEDIATE CODE: R360 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20091020 Year of fee payment: 3 |
|
R360 | Written notification for declining of transfer of rights |
Free format text: JAPANESE INTERMEDIATE CODE: R360 |
|
R371 | Transfer withdrawn |
Free format text: JAPANESE INTERMEDIATE CODE: R371 |
|
S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20091020 Year of fee payment: 3 |
|
R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20091020 Year of fee payment: 3 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20091020 Year of fee payment: 3 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20101020 Year of fee payment: 4 |
|
LAPS | Cancellation because of no payment of annual fees |