JPH1067731A5 - - Google Patents
Info
- Publication number
- JPH1067731A5 JPH1067731A5 JP1997144393A JP14439397A JPH1067731A5 JP H1067731 A5 JPH1067731 A5 JP H1067731A5 JP 1997144393 A JP1997144393 A JP 1997144393A JP 14439397 A JP14439397 A JP 14439397A JP H1067731 A5 JPH1067731 A5 JP H1067731A5
- Authority
- JP
- Japan
- Prior art keywords
- carbon atoms
- phenyl
- cycloalkyl
- alkyl
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19622370:9 | 1996-06-04 | ||
| DE19622370A DE19622370A1 (de) | 1996-06-04 | 1996-06-04 | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPH1067731A JPH1067731A (ja) | 1998-03-10 |
| JPH1067731A5 true JPH1067731A5 (cg-RX-API-DMAC7.html) | 2005-04-07 |
| JP4101904B2 JP4101904B2 (ja) | 2008-06-18 |
Family
ID=7796095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP14439397A Expired - Fee Related JP4101904B2 (ja) | 1996-06-04 | 1997-06-03 | オルト−置換されたベンゾイルグアニジン、その製法、医薬または診断剤としてのその使用およびそれを含有する医薬 |
Country Status (29)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6410563B1 (en) | 1999-12-22 | 2002-06-25 | Merck Frosst Canada & Co. | Substituted 8-arylquinoline phosphodiesterase-4 inhibitors |
| MY123585A (en) | 2000-03-23 | 2006-05-31 | Merck Canada Inc | Tri-aryl-substituted-ethane pde4 inhibitors. |
| US6639077B2 (en) | 2000-03-23 | 2003-10-28 | Merck Frosst Canada & Co. | Tri-aryl-substituted-ethane PDE4 inhibitors |
| CA2407780A1 (en) | 2000-05-25 | 2001-11-29 | Merck Frosst Canada & Co./Merck Frosst Canada & Cie | Fluoroalkoxy-substituted benzamide dichloropyridinyl n-oxide pde4 inhibitor |
| US6740666B2 (en) | 2000-12-20 | 2004-05-25 | Merck & Co., Inc. | Substituted 8-arylquinoline phosphodiesterase-4 inhibitors |
| DE60205899T2 (de) | 2001-05-24 | 2006-06-29 | Merck Frosst Canada & Co, Kirkland | 1-biaryl-1,8-naphthyridin-4-one als phosphodieseterase-inhibitoren |
| JO2311B1 (en) | 2001-08-29 | 2005-09-12 | ميرك فروست كندا ليمتد | Alkyl inhibitors Ariel phosphodiesterase-4 |
| US7592337B2 (en) | 2002-03-12 | 2009-09-22 | Merck & Co., Inc. | Di-aryl substituted tetrazole modulators of metabotropic glutamate receptor-5 |
| GB0916163D0 (en) * | 2009-09-15 | 2009-10-28 | Shire Llc | Prodrugs of guanfacine |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ284456B6 (cs) * | 1992-02-15 | 1998-12-16 | Hoechst Aktiengesellschaft | Aminosubstituované benzoylguanidiny, způsob jejich přípravy, jejich použití jako léčiv a léčivo, které je obsahuje |
| DE59403818D1 (de) * | 1993-02-20 | 1997-10-02 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, als Inhibitoren des zellulären Na+/H+-Austauschs oder als Diagnostikum sowie sie enthaltendes Medikament |
| DE4318756A1 (de) * | 1993-06-05 | 1994-12-08 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4327244A1 (de) * | 1993-08-13 | 1995-02-16 | Hoechst Ag | Harnstoffsubstituierte Benzoylguandine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4328869A1 (de) * | 1993-08-27 | 1995-03-02 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE4422685A1 (de) * | 1994-06-29 | 1996-01-04 | Hoechst Ag | Ortho-amino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
-
1996
- 1996-06-04 DE DE19622370A patent/DE19622370A1/de not_active Withdrawn
-
1997
- 1997-05-22 DK DK97108258T patent/DK0811610T3/da active
- 1997-05-22 SI SI9730284T patent/SI0811610T1/xx unknown
- 1997-05-22 DE DE59705495T patent/DE59705495D1/de not_active Expired - Lifetime
- 1997-05-22 ES ES97108258T patent/ES2166487T3/es not_active Expired - Lifetime
- 1997-05-22 AT AT97108258T patent/ATE209630T1/de not_active IP Right Cessation
- 1997-05-22 PT PT97108258T patent/PT811610E/pt unknown
- 1997-05-22 EP EP97108258A patent/EP0811610B1/de not_active Expired - Lifetime
- 1997-05-30 NZ NZ314973A patent/NZ314973A/en unknown
- 1997-06-02 CZ CZ19971696A patent/CZ289411B6/cs not_active IP Right Cessation
- 1997-06-02 ID IDP971869A patent/ID17038A/id unknown
- 1997-06-02 AU AU24650/97A patent/AU723665B2/en not_active Ceased
- 1997-06-02 TW TW086107502A patent/TW429243B/zh active
- 1997-06-02 AR ARP970102385A patent/AR008761A1/es unknown
- 1997-06-02 TR TR97/00453A patent/TR199700453A2/xx unknown
- 1997-06-02 CN CN971054797A patent/CN1064956C/zh not_active Expired - Fee Related
- 1997-06-02 SK SK696-97A patent/SK282628B6/sk unknown
- 1997-06-03 HU HU9700989A patent/HUP9700989A3/hu unknown
- 1997-06-03 HR HR970304A patent/HRP970304B1/xx not_active IP Right Cessation
- 1997-06-03 KR KR1019970022785A patent/KR980002019A/ko not_active Ceased
- 1997-06-03 JP JP14439397A patent/JP4101904B2/ja not_active Expired - Fee Related
- 1997-06-03 MX MX9704094A patent/MX9704094A/es unknown
- 1997-06-03 RU RU97109913/04A patent/RU2214397C2/ru not_active IP Right Cessation
- 1997-06-03 US US08/868,077 patent/US6011063A/en not_active Expired - Lifetime
- 1997-06-03 ZA ZA9704869A patent/ZA974869B/xx unknown
- 1997-06-03 PL PL97320327A patent/PL185757B1/pl not_active IP Right Cessation
- 1997-06-03 IL IL12098897A patent/IL120988A0/xx unknown
- 1997-06-03 NO NO19972527A patent/NO310188B1/no not_active IP Right Cessation
- 1997-06-04 BR BR9703440A patent/BR9703440A/pt not_active IP Right Cessation
- 1997-06-04 CA CA002206758A patent/CA2206758C/en not_active Expired - Fee Related
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