JPH09328419A - 安定な水中油形エマルジョン及びその製造方法 - Google Patents

安定な水中油形エマルジョン及びその製造方法

Info

Publication number
JPH09328419A
JPH09328419A JP9054400A JP5440097A JPH09328419A JP H09328419 A JPH09328419 A JP H09328419A JP 9054400 A JP9054400 A JP 9054400A JP 5440097 A JP5440097 A JP 5440097A JP H09328419 A JPH09328419 A JP H09328419A
Authority
JP
Japan
Prior art keywords
oil
carotenoid
emulsion
stable
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9054400A
Other languages
English (en)
Japanese (ja)
Other versions
JPH09328419A5 (enExample
Inventor
Loni Dr Schweikert
シュヴァイケルト ロニ
Karl Dr Kolter
コルター カール
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of JPH09328419A publication Critical patent/JPH09328419A/ja
Publication of JPH09328419A5 publication Critical patent/JPH09328419A5/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/01Hydrocarbons
    • A61K31/015Hydrocarbons carbocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/01Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/375Ascorbic acid, i.e. vitamin C; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP9054400A 1996-03-11 1997-03-10 安定な水中油形エマルジョン及びその製造方法 Pending JPH09328419A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19609476A DE19609476A1 (de) 1996-03-11 1996-03-11 Stabile zur parenteralen Verabreichung geeignete Carotinoid-Emulsionen
DE19609476.3 1996-03-11

Publications (2)

Publication Number Publication Date
JPH09328419A true JPH09328419A (ja) 1997-12-22
JPH09328419A5 JPH09328419A5 (enExample) 2004-12-16

Family

ID=7787923

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9054400A Pending JPH09328419A (ja) 1996-03-11 1997-03-10 安定な水中油形エマルジョン及びその製造方法

Country Status (9)

Country Link
US (1) US5925684A (enExample)
EP (1) EP0800824B1 (enExample)
JP (1) JPH09328419A (enExample)
CN (1) CN1074917C (enExample)
AT (1) ATE204472T1 (enExample)
AU (1) AU1620397A (enExample)
CA (1) CA2199414A1 (enExample)
DE (2) DE19609476A1 (enExample)
ES (1) ES2163055T3 (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003520769A (ja) * 1999-05-27 2003-07-08 アボット・ラボラトリーズ 注射可能な麻酔製剤
JP2004505033A (ja) * 2000-08-01 2004-02-19 ユニバーシティ オブ フロリダ 薬物を可溶化するための新規なマイクロエマルジョンおよびミセルシステム
WO2008081905A1 (ja) 2007-01-05 2008-07-10 Fujifilm Corporation 分散組成物及びスキンケア用化粧料並びに分散組成物の製造方法
WO2008088037A1 (ja) * 2007-01-18 2008-07-24 National University Corporation Chiba University 微粒子製剤
WO2012133246A1 (ja) * 2011-03-30 2012-10-04 富士フイルム株式会社 カロチノイド含有組成物及びその製造方法

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DE19653410A1 (de) * 1996-12-20 1998-06-25 Basf Ag Verwendung von Carotinoid-Solubilisaten zum Färben von Lebensmitteln und pharmazeutischen Zubereitungen
AT408186B (de) * 1998-12-15 2001-09-25 Sanochemia Pharmazeutika Ag Wässerige zubereitung von beta-carotin
WO2001028519A1 (de) * 1999-10-20 2001-04-26 Vesifact Ag Mikroemulsion-prekonzentrate und mikroemulsionen
DE19951615A1 (de) * 1999-10-26 2001-05-03 Basf Ag Verfahren zur Stabilisierung von flüssigen, wäßrigen Präparaten fettlöslicher Substanzen
US6617305B1 (en) * 2000-10-10 2003-09-09 Ingredient Innovations Internaitonal Stable aqueous dispersion of nutrients
US6455072B1 (en) * 1999-10-28 2002-09-24 Ingredient Innovations International Stable aqueous dispersion of nutrients
EP1227780A4 (en) * 1999-10-28 2006-09-06 Ingredient Innovations Interna STABLE AQUEOUS DISPERSION OF NUTRIENT ELEMENTS
US20020006959A1 (en) * 2000-05-01 2002-01-17 Henderson Samuel T. Use of medium chain triglycerides for the treatment and prevention of Alzheimer's Disease and other diseases resulting from reduced Neuronal Metabolism
US6835750B1 (en) 2000-05-01 2004-12-28 Accera, Inc. Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II
US20070179197A1 (en) * 2000-05-01 2007-08-02 Accera, Inc. Compositions and methods for improving or preserving brain function
ATE269301T1 (de) * 2001-01-24 2004-07-15 Kuraray Co Verfahren zur herstellung von carotinoid emulsionen
US6635293B2 (en) * 2001-10-23 2003-10-21 Kemin Foods, L.C. Finely dispersed carotenoid suspensions for use in foods and a process for their preparation
DE10221212A1 (de) * 2002-05-13 2003-11-27 Andreas Maack Sporopollenin enthaltende lösliche Zusammensetzung und Verwendung
US20050148517A1 (en) * 2002-07-29 2005-07-07 Lockwood Samuel F. Carotenoid ether analogs or derivatives for controlling connexin 43 expression
US20050049248A1 (en) * 2002-07-29 2005-03-03 Lockwood Samuel Fournier Carotenoid ether analogs or derivatives for controlling C-reactive protein levels
US20050143475A1 (en) * 2002-07-29 2005-06-30 Lockwood Samuel F. Carotenoid analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury
US7375133B2 (en) * 2002-07-29 2008-05-20 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US20050059659A1 (en) * 2002-07-29 2005-03-17 Lockwood Samuel Fournier Carotenoid analogs or derivatives for controlling C-reactive protein levels
BRPI0313155B8 (pt) 2002-07-29 2021-05-25 Cardax Pharmaceuticals Inc composto químico derivado ou análogo de carotenóide, composição farmacêutica, e, uso do composto
US20050004235A1 (en) * 2002-07-29 2005-01-06 Lockwood Samuel Fournier Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease
US7521584B2 (en) * 2002-07-29 2009-04-21 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for the inhibition and amelioration of disease
US7320997B2 (en) * 2002-07-29 2008-01-22 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease
US20050009788A1 (en) * 2002-07-29 2005-01-13 Lockwood Samuel Fournier Carotenoid ester analogs or derivatives for controlling connexin 43 expression
US7763649B2 (en) * 2002-07-29 2010-07-27 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for controlling connexin 43 expression
US7723327B2 (en) * 2002-07-29 2010-05-25 Cardax Pharmaceuticals, Inc. Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease
US7345091B2 (en) * 2002-07-29 2008-03-18 Cardax Pharmaceuticals, Inc. Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US20050026874A1 (en) * 2002-07-29 2005-02-03 Lockwood Samuel Fournier Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease
US6855359B2 (en) * 2002-11-15 2005-02-15 Cargill, Incorporated Soluble isoflavone compositions
WO2004077938A2 (en) * 2003-03-06 2004-09-16 Accera Inc. Novel chemical entities and methods for their use in treatment of metabolic disorders
EP1728505B1 (en) * 2004-03-24 2014-06-04 Takeda Pharmaceutical Company Limited Preparation with elevated content
US20060058269A1 (en) * 2004-04-14 2006-03-16 Lockwood Samuel F Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation
WO2005102356A1 (en) * 2004-04-14 2005-11-03 Hawaii Biotech, Inc. Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation
DE102004051245A1 (de) * 2004-10-20 2006-04-27 Aquanova German Solubilisate Technologies (Agt) Gmbh Vitamin C-Solubilisat
US20060252775A1 (en) * 2005-05-03 2006-11-09 Henderson Samuel T Methods for reducing levels of disease associated proteins
EP1915144A4 (en) * 2005-06-20 2009-08-19 Accera Inc METHOD FOR REDUCING OXIDATIVE DAMAGE AND IMPROVING MITOCHONDRIA EFFICIENCY
KR20090003148A (ko) 2006-04-03 2009-01-09 액세라인크 나이와 관련된 기억 손상의 치료를 위한 케톤 생성조성물의 용도
JP5459939B2 (ja) * 2006-06-09 2014-04-02 富士フイルム株式会社 カロチノイド含有エマルジョン組成物、その製造方法、それを含む食品及び化粧品
US7435846B2 (en) 2006-08-18 2008-10-14 Industrial Organica, S.A. De C.V. Absorption and bioavailability of carotenoids, formulations and applications
CA2669392C (en) * 2006-11-17 2016-05-10 Abbott Gmbh & Co. Kg Nanocrystals for use in topical cosmetic formulations and method of production thereof
US20080131515A1 (en) * 2006-12-01 2008-06-05 Fujifilm Corporation Emulsion composition, and foods and cosmetics containing the emulsion composition
DE102007015701A1 (de) * 2007-03-19 2008-09-25 Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh Neue pharmazeutische Zusammensetzungen für die Lipolyse und Verfahren zu deren Herstellung
AU2008282130B2 (en) 2007-07-31 2014-08-21 Cerecin Inc. Use of genomic testing and ketogenic compounds for treatment of reduced cognitive function
EP2303036A1 (en) * 2008-07-03 2011-04-06 Accera, Inc. Monoglyceride of acetoacetate and derivatives for the treatment of neurological disorders
US8105809B2 (en) * 2008-07-03 2012-01-31 Accera, Inc. Enzymatic synthesis of acetoacetate esters and derivatives
US20120157547A1 (en) 2010-12-21 2012-06-21 Ricardo Montoya-Olvera Compositions and applications of carotenoids of improved absorption and bioavailability
CN102552293B (zh) * 2011-12-31 2014-05-21 沈阳药科大学 一种注射用复合维生素亚微乳冻干粉针及其制备方法
CN102525923B (zh) * 2012-02-16 2014-09-10 中国农业大学 类胡萝卜素乳液及微胶囊的制备方法
WO2014003594A1 (en) 2012-06-25 2014-01-03 Druzhinin Dmitry Aqueous-lipidic carotenoid-containing compositions
SG10201702500RA (en) * 2013-12-11 2017-05-30 Health Ever Biotech Co Ltd Pharmaceutical compositions of carotenoid
US10342775B2 (en) * 2015-05-22 2019-07-09 Fresenius Kabi Deutschland Gmbh Vitamin A for parenteral administration
WO2016188876A1 (en) * 2015-05-22 2016-12-01 Fresenius Kabi Deutschland Gmbh Vitamin a for parenteral administration
CN106617050A (zh) * 2016-11-08 2017-05-10 云南爱尔康生物技术有限公司 一种岩藻黄素纳米乳液及其制备方法
CN107271378B (zh) * 2017-04-13 2019-12-20 云南民族大学 虾青素抗脂质过氧化活性的测定方法
US20200383933A1 (en) * 2017-09-05 2020-12-10 Universidad De Chile Method for obtaining nanostructures with carotenoids and nanostructures obtained
CN111165824A (zh) * 2020-01-21 2020-05-19 北京金康普食品科技有限公司 护眼微量营养素预混料乳剂及其制备方法和应用
CN111296730A (zh) * 2020-03-06 2020-06-19 广州市食品工业研究所有限公司 一种稳定性好的叶黄素纳米乳液及其制备方法

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CH420822A (de) * 1960-10-17 1966-09-15 Hoffmann La Roche Wasserdispergierbare Carotinoidzubereitung
DE2236899A1 (de) * 1972-07-27 1974-02-07 Philips Patentverwaltung Mit wasser mischbare carotinoidemulsion
DE2254105A1 (de) * 1972-11-04 1974-05-16 Philips Patentverwaltung Verfahren zur herstellung von carotinoid-emulsionen
US4107343A (en) * 1976-11-08 1978-08-15 Scm Corporation Whippable emulsion stable at room temperature
DE3048000A1 (de) * 1980-12-19 1982-07-15 Basf Ag Stabile injizierbare (beta)-carotin-solubilisate und verfahren zu ihrer herstellung
JPS5910511A (ja) * 1982-07-07 1984-01-20 Eisai Co Ltd 脂溶性物質含有水性液
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FR2630346B1 (fr) * 1988-04-22 1991-03-22 Dubois Jacques Produits nouveaux comportant une emulsion d'eau et d'hydrocarbures paraffiniques huileux additionnes d'extraits de lecithine et procedes de fabrication
DE4031094A1 (de) * 1990-10-02 1992-04-09 Basf Ag Verfahren zur herstellung von stabilen injizierbaren (beta)-carotin-solubilisaten
DE4200728A1 (de) * 1992-01-14 1993-07-15 Basf Ag Stabile, fluessige praeparate fettloeslicher substanzen
IL101007A (en) * 1992-02-18 1997-08-14 Pharmos Ltd Dry stable compositions prepared by lyophilization
DE69430799T2 (de) * 1993-03-22 2003-02-13 Cognis Australien Pty.Ltd., Victoria Wasserdispersible therapeutische carotenoid verbindungen
US5705180A (en) * 1993-03-22 1998-01-06 Betatene Limited Therapeutic agent for the treatment of melanomas
DE4405545A1 (de) * 1994-02-22 1995-08-31 Dietl Hans Fettlösliche Vitamine enthaltende Zubereitung zur oralen Applikation

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003520769A (ja) * 1999-05-27 2003-07-08 アボット・ラボラトリーズ 注射可能な麻酔製剤
JP2004505033A (ja) * 2000-08-01 2004-02-19 ユニバーシティ オブ フロリダ 薬物を可溶化するための新規なマイクロエマルジョンおよびミセルシステム
JP4932123B2 (ja) * 2000-08-01 2012-05-16 ユニバーシティ オブ フロリダ 薬物を可溶化するための新規なマイクロエマルジョンおよびミセルシステム
WO2008081905A1 (ja) 2007-01-05 2008-07-10 Fujifilm Corporation 分散組成物及びスキンケア用化粧料並びに分散組成物の製造方法
WO2008088037A1 (ja) * 2007-01-18 2008-07-24 National University Corporation Chiba University 微粒子製剤
JP5515075B2 (ja) * 2007-01-18 2014-06-11 国立大学法人 千葉大学 微粒子製剤
WO2012133246A1 (ja) * 2011-03-30 2012-10-04 富士フイルム株式会社 カロチノイド含有組成物及びその製造方法
JP2012214462A (ja) * 2011-03-30 2012-11-08 Fujifilm Corp カロチノイド含有組成物及びその製造方法

Also Published As

Publication number Publication date
AU1620397A (en) 1997-09-18
CA2199414A1 (en) 1997-09-11
EP0800824B1 (de) 2001-08-22
ATE204472T1 (de) 2001-09-15
US5925684A (en) 1999-07-20
EP0800824A1 (de) 1997-10-15
CN1164387A (zh) 1997-11-12
DE19609476A1 (de) 1997-09-18
CN1074917C (zh) 2001-11-21
DE59704347D1 (de) 2001-09-27
ES2163055T3 (es) 2002-01-16

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