JPH0827277B2 - 試薬組成物及びその全血中の網状赤血球の同定と特性表示のための使用 - Google Patents
試薬組成物及びその全血中の網状赤血球の同定と特性表示のための使用Info
- Publication number
- JPH0827277B2 JPH0827277B2 JP4350137A JP35013792A JPH0827277B2 JP H0827277 B2 JPH0827277 B2 JP H0827277B2 JP 4350137 A JP4350137 A JP 4350137A JP 35013792 A JP35013792 A JP 35013792A JP H0827277 B2 JPH0827277 B2 JP H0827277B2
- Authority
- JP
- Japan
- Prior art keywords
- concentration
- reticulocytes
- reagent composition
- cells
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1429—Signal processing
- G01N15/1433—Signal processing using image recognition
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
- G01N2015/012—Red blood cells
- G01N2015/014—Reticulocytes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1486—Counting the particles
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Ecology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/802,585 US5360739A (en) | 1991-12-05 | 1991-12-05 | Methods for the identification and characterization of reticulocytes in whole blood |
| US07/802585 | 1991-12-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH06180315A JPH06180315A (ja) | 1994-06-28 |
| JPH0827277B2 true JPH0827277B2 (ja) | 1996-03-21 |
Family
ID=25184134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4350137A Expired - Lifetime JPH0827277B2 (ja) | 1991-12-05 | 1992-12-04 | 試薬組成物及びその全血中の網状赤血球の同定と特性表示のための使用 |
Country Status (12)
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| US5793485A (en) * | 1995-03-20 | 1998-08-11 | Sandia Corporation | Resonant-cavity apparatus for cytometry or particle analysis |
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| JP3425830B2 (ja) * | 1995-10-06 | 2003-07-14 | シスメックス株式会社 | 新規化合物とその用途 |
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| US6025201A (en) * | 1995-12-28 | 2000-02-15 | Bayer Corporation | Highly sensitive, accurate, and precise automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples |
| US5817519A (en) | 1995-12-28 | 1998-10-06 | Bayer Corporation | Automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples |
| TW379284B (en) * | 1996-04-12 | 2000-01-11 | Toa Medical Electronics | Agent for detecting reticulocyte |
| DE69739456D1 (de) * | 1996-07-30 | 2009-07-30 | Siemens Healthcare Diagnostics | Optisches System für Blutanalysegerät |
| US5830764A (en) * | 1996-11-12 | 1998-11-03 | Bayer Corporation | Methods and reagent compositions for the determination of membrane surface area and sphericity of erythrocytes and reticulocytes for the diagnosis of red blood cell disorders |
| FR2759166B1 (fr) * | 1997-01-31 | 1999-04-23 | Abx Sa | Reactif de coloration pour la determination de cellules sanguines |
| US6114173A (en) * | 1997-04-03 | 2000-09-05 | Bayer Corporation | Fully automated method and reagent composition therefor for rapid identification and characterization of reticulocytes erythrocytes and platelets in whole blood |
| US5874311A (en) * | 1997-11-21 | 1999-02-23 | Coulter International Corp. | Method for differentiation of reticulocytes in blood |
| US6197593B1 (en) | 1998-10-20 | 2001-03-06 | Coulter International Corp. | Method for enumerating blood cells |
| US6271035B1 (en) | 1998-10-20 | 2001-08-07 | Coulter International Corp. | Methods and compositions for rapid staining of nucleic acids in whole cells |
| US6060322A (en) * | 1998-10-20 | 2000-05-09 | Coulter International Corp. | Method for identification of reticulated cells |
| US6187592B1 (en) * | 1998-12-23 | 2001-02-13 | Sandia Corporation | Method for determining properties of red blood cells |
| BR0009420A (pt) * | 1999-03-31 | 2002-04-09 | Bayer Ag | Método de detecção de diluição simples e canal único |
| US6368864B1 (en) | 2000-05-05 | 2002-04-09 | Coulter International Corp. | Dyes and methods of reticulocyte enumeration |
| US6784981B1 (en) | 2000-06-02 | 2004-08-31 | Idexx Laboratories, Inc. | Flow cytometry-based hematology system |
| EP1203944B1 (de) * | 2000-11-06 | 2006-03-01 | Hofstetter, Alfons, Prof.Dr.med. | Tumorzellenidentifizierungsverfahren |
| US6630990B2 (en) | 2001-06-05 | 2003-10-07 | Abbott Laboratories | Optical method and apparatus for red blood cell differentiation on a cell-by-cell basis, and simultaneous analysis of white blood cell differentiation |
| DE10212960A1 (de) * | 2002-03-22 | 2003-10-23 | Gnothis Holding Sa Ecublens | Verwendung von Oxazin-Farbstoffen als Markierungsgruppen für die Einzelmolekülanalyse |
| CA2428740A1 (en) | 2002-05-20 | 2003-11-20 | Bayer Corporation | Automated method and reagent therefor for assaying body fluid samples such as cerebrospinal fluid (csf) |
| JP4417143B2 (ja) * | 2004-03-11 | 2010-02-17 | シスメックス株式会社 | 試料分析装置、プログラムおよびそのプログラムを記録した記録媒体 |
| US7110192B2 (en) * | 2005-01-12 | 2006-09-19 | Dako Denmark A/S | System and method for a composite lens for a flow cytometer |
| US7541190B2 (en) * | 2005-02-07 | 2009-06-02 | Beckman Coulter, Inc. | Method of measurement of cellular hemoglobin |
| CN101231243B (zh) * | 2007-01-24 | 2011-11-16 | 深圳迈瑞生物医疗电子股份有限公司 | 网织红细胞检测试剂及检测方法 |
| CN101236158B (zh) * | 2007-01-29 | 2011-11-16 | 深圳迈瑞生物医疗电子股份有限公司 | 网织红细胞检测方法及检测装置 |
| CN101349644B (zh) | 2007-07-20 | 2012-06-27 | 深圳迈瑞生物医疗电子股份有限公司 | 一种白细胞分类试剂和其使用方法 |
| US8102161B2 (en) * | 2007-09-25 | 2012-01-24 | Tdk Corporation | Stable output in a switching power supply by smoothing the output of the secondary coil |
| CN105440725A (zh) | 2008-01-04 | 2016-03-30 | 深圳迈瑞生物医疗电子股份有限公司 | 不对称菁类荧光染料，组合物及在生物样品染色中的用途 |
| US7903241B2 (en) * | 2008-03-21 | 2011-03-08 | Abbott Point Of Care, Inc. | Method and apparatus for determining red blood cell indices of a blood sample utilizing the intrinsic pigmentation of hemoglobin contained within the red blood cells |
| CN101602762B (zh) | 2008-06-10 | 2013-10-16 | 深圳迈瑞生物医疗电子股份有限公司 | 不对称菁类化合物、其制备方法及应用 |
| CN101726579B (zh) | 2008-10-17 | 2014-06-18 | 深圳迈瑞生物医疗电子股份有限公司 | 血液检测试剂和方法 |
| US8367358B2 (en) | 2008-12-17 | 2013-02-05 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Reagent, kit and method for differentiating and counting leukocytes |
| US8906309B2 (en) * | 2009-04-27 | 2014-12-09 | Abbott Laboratories | Method for discriminating red blood cells from white blood cells by using forward scattering from a laser in an automated hematology analyzer |
| CN101988082B (zh) | 2009-07-31 | 2015-04-08 | 深圳迈瑞生物医疗电子股份有限公司 | 白细胞分类计数试剂、试剂盒及其制备方法和白细胞分类计数的方法 |
| US8906308B2 (en) | 2010-01-15 | 2014-12-09 | Abbott Laboratories | Method for determining volume and hemoglobin content of individual red blood cells |
| FR2956207B1 (fr) | 2010-02-10 | 2012-05-04 | Horiba Abx Sas | Dispositif et procede de mesures multiparametriques de microparticules dans un fluide |
| US8488111B2 (en) * | 2011-04-15 | 2013-07-16 | Constitution Medical, Inc. | Measuring volume and constituents of cells |
| JP5665811B2 (ja) * | 2012-08-02 | 2015-02-04 | 国立大学法人九州大学 | 光誘起蛍光測定器 |
| JP7191975B2 (ja) | 2018-03-30 | 2022-12-19 | アイデックス ラボラトリーズ インコーポレイテッド | フローサイトメータ、そのレーザ光学アセンブリ、およびレーザ光学アセンブリの組立方法 |
| CN112639467B (zh) * | 2018-12-25 | 2024-04-09 | 深圳迈瑞生物医疗电子股份有限公司 | 血小板模拟粒子及其制备方法以及含该模拟粒子的质控物或校准物 |
| KR102340869B1 (ko) * | 2019-05-09 | 2021-12-20 | (주)크레용테크놀러지즈 | 이온 전도성 필름을 이용한 전기 영동 방식의 생체 시료 염색 방법 및 염색 장치 |
| CN114667443A (zh) * | 2019-11-20 | 2022-06-24 | 贝克顿·迪金森公司 | 具有可调灵敏度的光检测模块 |
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-
1991
- 1991-12-05 US US07/802,585 patent/US5360739A/en not_active Expired - Lifetime
-
1992
- 1992-09-04 IL IL103055A patent/IL103055A/xx not_active IP Right Cessation
- 1992-09-09 CA CA002077789A patent/CA2077789C/en not_active Expired - Fee Related
- 1992-10-15 US US07/961,582 patent/US5411891A/en not_active Expired - Lifetime
- 1992-11-05 AU AU28167/92A patent/AU2816792A/en not_active Abandoned
- 1992-11-27 EP EP92120309A patent/EP0545315B1/en not_active Expired - Lifetime
- 1992-11-27 ES ES92120309T patent/ES2111600T3/es not_active Expired - Lifetime
- 1992-11-27 AT AT92120309T patent/ATE161953T1/de not_active IP Right Cessation
- 1992-11-27 DK DK92120309T patent/DK0545315T3/da active
- 1992-11-27 DE DE69223931T patent/DE69223931T2/de not_active Expired - Fee Related
- 1992-12-03 KR KR1019920023171A patent/KR100258394B1/ko not_active Expired - Fee Related
- 1992-12-04 JP JP4350137A patent/JPH0827277B2/ja not_active Expired - Lifetime
-
1993
- 1993-04-20 TW TW082103032A patent/TW316948B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| US5360739A (en) | 1994-11-01 |
| CA2077789A1 (en) | 1993-06-06 |
| EP0545315A1 (en) | 1993-06-09 |
| DE69223931T2 (de) | 1998-04-30 |
| AU2816792A (en) | 1993-06-10 |
| DK0545315T3 (da) | 1998-09-07 |
| ATE161953T1 (de) | 1998-01-15 |
| US5411891A (en) | 1995-05-02 |
| DE69223931D1 (de) | 1998-02-12 |
| KR100258394B1 (ko) | 2000-06-01 |
| CA2077789C (en) | 1997-09-09 |
| EP0545315B1 (en) | 1998-01-07 |
| ES2111600T3 (es) | 1998-03-16 |
| IL103055A0 (en) | 1993-02-21 |
| TW316948B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1997-10-01 |
| IL103055A (en) | 1997-07-13 |
| JPH06180315A (ja) | 1994-06-28 |
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