DE69223931T2 - Reagenszusammensetzungen und ihre Verwendung bei der Identifizierung und Charakterisierung von Retikulozyten in Vollblut - Google Patents

Reagenszusammensetzungen und ihre Verwendung bei der Identifizierung und Charakterisierung von Retikulozyten in Vollblut

Info

Publication number
DE69223931T2
DE69223931T2 DE69223931T DE69223931T DE69223931T2 DE 69223931 T2 DE69223931 T2 DE 69223931T2 DE 69223931 T DE69223931 T DE 69223931T DE 69223931 T DE69223931 T DE 69223931T DE 69223931 T2 DE69223931 T2 DE 69223931T2
Authority
DE
Germany
Prior art keywords
reticulocytes
cell
erythrocytes
hemoglobin
hemoglobin concentration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69223931T
Other languages
English (en)
Other versions
DE69223931D1 (de
Inventor
Sophie S Fan
Daniel Ben-David
Gregory M Collela
Albert Cupo
Gena Fischer
Leonard Ornstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Icahn School of Medicine at Mount Sinai
Original Assignee
Bayer AG
Bayer Corp
Mount Sinai School of Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp, Mount Sinai School of Medicine filed Critical Bayer AG
Publication of DE69223931D1 publication Critical patent/DE69223931D1/de
Application granted granted Critical
Publication of DE69223931T2 publication Critical patent/DE69223931T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples
    • G01N15/1433—
    • G01N2015/014—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1486—Counting the particles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
DE69223931T 1991-12-05 1992-11-27 Reagenszusammensetzungen und ihre Verwendung bei der Identifizierung und Charakterisierung von Retikulozyten in Vollblut Expired - Fee Related DE69223931T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/802,585 US5360739A (en) 1991-12-05 1991-12-05 Methods for the identification and characterization of reticulocytes in whole blood

Publications (2)

Publication Number Publication Date
DE69223931D1 DE69223931D1 (de) 1998-02-12
DE69223931T2 true DE69223931T2 (de) 1998-04-30

Family

ID=25184134

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69223931T Expired - Fee Related DE69223931T2 (de) 1991-12-05 1992-11-27 Reagenszusammensetzungen und ihre Verwendung bei der Identifizierung und Charakterisierung von Retikulozyten in Vollblut

Country Status (12)

Country Link
US (2) US5360739A (de)
EP (1) EP0545315B1 (de)
JP (1) JPH0827277B2 (de)
KR (1) KR100258394B1 (de)
AT (1) ATE161953T1 (de)
AU (1) AU2816792A (de)
CA (1) CA2077789C (de)
DE (1) DE69223931T2 (de)
DK (1) DK0545315T3 (de)
ES (1) ES2111600T3 (de)
IL (1) IL103055A (de)
TW (1) TW316948B (de)

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DE10212960A1 (de) * 2002-03-22 2003-10-23 Gnothis Holding Sa Ecublens Verwendung von Oxazin-Farbstoffen als Markierungsgruppen für die Einzelmolekülanalyse

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CN102027368B (zh) * 2008-03-21 2014-02-26 艾博特健康公司 利用红细胞内含有的血红蛋白的本征色素沉着来确定血样的红细胞指数的方法及设备
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CN101726579B (zh) 2008-10-17 2014-06-18 深圳迈瑞生物医疗电子股份有限公司 血液检测试剂和方法
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10212960A1 (de) * 2002-03-22 2003-10-23 Gnothis Holding Sa Ecublens Verwendung von Oxazin-Farbstoffen als Markierungsgruppen für die Einzelmolekülanalyse

Also Published As

Publication number Publication date
CA2077789C (en) 1997-09-09
EP0545315A1 (de) 1993-06-09
IL103055A (en) 1997-07-13
JPH0827277B2 (ja) 1996-03-21
US5411891A (en) 1995-05-02
KR100258394B1 (ko) 2000-06-01
JPH06180315A (ja) 1994-06-28
DE69223931D1 (de) 1998-02-12
EP0545315B1 (de) 1998-01-07
CA2077789A1 (en) 1993-06-06
US5360739A (en) 1994-11-01
IL103055A0 (en) 1993-02-21
AU2816792A (en) 1993-06-10
ES2111600T3 (es) 1998-03-16
ATE161953T1 (de) 1998-01-15
DK0545315T3 (da) 1998-09-07
TW316948B (de) 1997-10-01

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