BR112022025798A2 - Citômetro de fluxo de um analisador sanguineo, e, método para detectar reticulócitos e granulócitos - Google Patents

Citômetro de fluxo de um analisador sanguineo, e, método para detectar reticulócitos e granulócitos

Info

Publication number
BR112022025798A2
BR112022025798A2 BR112022025798A BR112022025798A BR112022025798A2 BR 112022025798 A2 BR112022025798 A2 BR 112022025798A2 BR 112022025798 A BR112022025798 A BR 112022025798A BR 112022025798 A BR112022025798 A BR 112022025798A BR 112022025798 A2 BR112022025798 A2 BR 112022025798A2
Authority
BR
Brazil
Prior art keywords
blood analyzer
flow cytometer
granulocytes
flow cell
laser
Prior art date
Application number
BR112022025798A
Other languages
English (en)
Inventor
Christian Misener Garland
Ryan Moon Michael
Franklin Mcelwain Spencer
Original Assignee
Idexx Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idexx Lab Inc filed Critical Idexx Lab Inc
Publication of BR112022025798A2 publication Critical patent/BR112022025798A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1434—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
    • G01N15/1436—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement the optical arrangement forming an integrated apparatus with the sample container, e.g. a flow cell
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1434—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B19/00—Condensers, e.g. light collectors or similar non-imaging optics
    • G02B19/0033—Condensers, e.g. light collectors or similar non-imaging optics characterised by the use
    • G02B19/0047—Condensers, e.g. light collectors or similar non-imaging optics characterised by the use for use with a light source
    • G02B19/0052—Condensers, e.g. light collectors or similar non-imaging optics characterised by the use for use with a light source the light source comprising a laser diode
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/09—Beam shaping, e.g. changing the cross-sectional area, not otherwise provided for
    • G02B27/0916—Adapting the beam shape of a semiconductor light source such as a laser diode or an LED, e.g. for efficiently coupling into optical fibers
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B5/00—Optical elements other than lenses
    • G02B5/30—Polarising elements
    • G02B5/3083—Birefringent or phase retarding elements
    • G01N2015/016—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1434—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
    • G01N2015/144—Imaging characterised by its optical setup

Abstract

CITÔMETRO DE FLUXO DE UM ANALISADOR SANGUINEO, E, MÉTODO PARA DETECTAR RETICULÓCITOS E GRANULÓCITOS. Um citômetro de fluxo de um analisador sanguíneo que inclui um diodo laser elétrico transversal (TE), uma célula de fluxo, uma placa em quarto de onda (QWP), uma pluralidade de lentes e um detector de dispersão lateral. O diodo laser TE é configurado para emitir um feixe de laser ao longo de um eixo óptico e tem uma divergência de largura a meia altura (FWHM) de cerca de 16 graus a cerca de 25 graus. A QWP é disposta ao longo do eixo óptico entre o diodo laser TE e a célula de fluxo e configurada para polarizar circularmente o feixe de laser. A pluralidade de lentes é disposta entre o diodo laser TE e a célula de fluxo e configurada para focar o feixe de laser na célula de fluxo.
BR112022025798A 2020-06-17 2021-06-15 Citômetro de fluxo de um analisador sanguineo, e, método para detectar reticulócitos e granulócitos BR112022025798A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063040035P 2020-06-17 2020-06-17
PCT/US2021/037417 WO2021257553A1 (en) 2020-06-17 2021-06-15 Flow cytometer and laser optics assembly thereof

Publications (1)

Publication Number Publication Date
BR112022025798A2 true BR112022025798A2 (pt) 2023-01-10

Family

ID=77022183

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022025798A BR112022025798A2 (pt) 2020-06-17 2021-06-15 Citômetro de fluxo de um analisador sanguineo, e, método para detectar reticulócitos e granulócitos

Country Status (9)

Country Link
US (2) US11543342B2 (pt)
EP (1) EP4168773A1 (pt)
JP (1) JP2023526690A (pt)
KR (1) KR102547788B1 (pt)
CN (1) CN115917292B (pt)
AU (1) AU2021293085A1 (pt)
BR (1) BR112022025798A2 (pt)
CA (1) CA3182847A1 (pt)
WO (1) WO2021257553A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2020010052A (es) * 2018-03-30 2020-10-15 Idexx Lab Inc Citometro de flujo, ensamble de optica laser del mismo y metodos de ensamblaje del mismo.

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Also Published As

Publication number Publication date
EP4168773A1 (en) 2023-04-26
KR20230038484A (ko) 2023-03-20
WO2021257553A1 (en) 2021-12-23
AU2021293085A1 (en) 2023-02-16
US20230124317A1 (en) 2023-04-20
US11879828B2 (en) 2024-01-23
CN115917292A (zh) 2023-04-04
CN115917292B (zh) 2023-08-25
JP2023526690A (ja) 2023-06-22
US11543342B2 (en) 2023-01-03
US20210396646A1 (en) 2021-12-23
KR102547788B1 (ko) 2023-06-26
CA3182847A1 (en) 2021-12-23

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