JPH0826064B2 - ステロイドペルアシルグリコシド類の製法 - Google Patents

ステロイドペルアシルグリコシド類の製法

Info

Publication number
JPH0826064B2
JPH0826064B2 JP5510090A JP51009093A JPH0826064B2 JP H0826064 B2 JPH0826064 B2 JP H0826064B2 JP 5510090 A JP5510090 A JP 5510090A JP 51009093 A JP51009093 A JP 51009093A JP H0826064 B2 JPH0826064 B2 JP H0826064B2
Authority
JP
Japan
Prior art keywords
zinc
tigogenin
reaction
cellobioside
steroid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP5510090A
Other languages
English (en)
Japanese (ja)
Other versions
JPH06510794A (ja
Inventor
アレン，ダグラス，ジョン，エム．
ブッシュ，フランク，ロバート
ランバート，ジョン，フランシス
シャイン，ルシェル，ジェームス
ワリスンキー，スタンレー，ウォルター
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Original Assignee
Pfizer Corp Belgium
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium filed Critical Pfizer Corp Belgium
Publication of JPH06510794A publication Critical patent/JPH06510794A/ja
Publication of JPH0826064B2 publication Critical patent/JPH0826064B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP5510090A 1991-11-25 1992-10-15 ステロイドペルアシルグリコシド類の製法 Expired - Lifetime JPH0826064B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79757491A 1991-11-25 1991-11-25
US797.574 1991-11-25
PCT/US1992/008638 WO1993011150A1 (en) 1991-11-25 1992-10-15 Method for making steroidal peracyl glycosides

Publications (2)

Publication Number Publication Date
JPH06510794A JPH06510794A (ja) 1994-12-01
JPH0826064B2 true JPH0826064B2 (ja) 1996-03-13

Family

ID=25171219

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5510090A Expired - Lifetime JPH0826064B2 (ja) 1991-11-25 1992-10-15 ステロイドペルアシルグリコシド類の製法

Country Status (13)

Country Link
EP (1) EP0619822A1 (enrdf_load_stackoverflow)
JP (1) JPH0826064B2 (enrdf_load_stackoverflow)
AU (1) AU659506B2 (enrdf_load_stackoverflow)
CA (1) CA2123684A1 (enrdf_load_stackoverflow)
FI (1) FI942394A0 (enrdf_load_stackoverflow)
HU (1) HUT67035A (enrdf_load_stackoverflow)
IL (1) IL103797A0 (enrdf_load_stackoverflow)
MX (1) MX9206761A (enrdf_load_stackoverflow)
NZ (1) NZ245244A (enrdf_load_stackoverflow)
PT (1) PT101088A (enrdf_load_stackoverflow)
TW (1) TW232699B (enrdf_load_stackoverflow)
WO (1) WO1993011150A1 (enrdf_load_stackoverflow)
ZA (1) ZA929081B (enrdf_load_stackoverflow)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2139104A1 (en) * 1992-06-26 1994-01-06 Michael P. Deninno Steroidal glycosides for treating hypercholesterolemia
NZ252006A (en) * 1992-06-26 1995-10-26 Pfizer Preparation of 1-o-steroidal peracyl-beta-glycosides
WO1994000478A1 (en) * 1992-06-26 1994-01-06 Pfizer Inc. Steroidal beta-o-cellobioside heptaalkanoate process
EP0696292A1 (en) * 1993-04-28 1996-02-14 Pfizer Inc. Spirostanyl glycosidal crystalline monohydrate
US5502038A (en) * 1993-06-21 1996-03-26 Medical Research Foundation Of Oregon Cholesterol sequestrant glycosides that inhibit intestinal cholesterol absorption
EP0737202A1 (en) * 1993-12-28 1996-10-16 Pfizer Inc. Hypocholesterolemic agents
US6150336A (en) * 1995-05-29 2000-11-21 Pfizer Inc. Steroidal glycosides
US5756470A (en) * 1996-10-29 1998-05-26 Schering Corporation Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents
US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
SI1355644T1 (sl) 2001-01-26 2006-10-31 Schering Corp Uporaba substituiranih azetidinonskih spojin za zdravljenje sitosterolemije
ES2290562T3 (es) 2001-01-26 2008-02-16 Schering Corporation Combinaciones del activador del receptor activado por el proliferador de los peroxisomas (ppar) fenofibrato con el inhibidor de la absorcion de esteroles ezetimiba para indicaciones vasculares.
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
PT1429756E (pt) 2001-09-21 2007-01-31 Schering Corp Tratamento de xantoma com derivados de azetidinona como inibidores de absorção de esteróis
MXPA05004811A (es) 2002-11-06 2005-07-22 Schering Corp Inhibidores de absorcion de colesterol para el tratamiento de trastornos autoinmunes.
ES2311806T3 (es) 2003-03-07 2009-02-16 Schering Corporation Compuesto de azetidinona sustituidos, fornulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP4589919B2 (ja) 2003-03-07 2010-12-01 シェーリング コーポレイション 高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用
WO2004081004A1 (en) 2003-03-07 2004-09-23 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4602005A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis
US4602003A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Synthetic compounds to inhibit intestinal absorption of cholesterol in the treatment of hypercholesterolemia

Also Published As

Publication number Publication date
MX9206761A (es) 1995-01-31
FI942394A7 (fi) 1994-05-24
FI942394L (fi) 1994-05-24
FI942394A0 (fi) 1994-05-24
HUT67035A (en) 1995-01-30
TW232699B (enrdf_load_stackoverflow) 1994-10-21
JPH06510794A (ja) 1994-12-01
AU2775892A (en) 1993-06-28
IL103797A0 (en) 1993-04-04
ZA929081B (en) 1994-05-24
NZ245244A (en) 1995-04-27
HU9401374D0 (en) 1994-08-29
PT101088A (pt) 1994-02-28
EP0619822A1 (en) 1994-10-19
CA2123684A1 (en) 1993-06-10
AU659506B2 (en) 1995-05-18
WO1993011150A1 (en) 1993-06-10

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