NZ245244A - Preparation of tigogenin-; 11-ketotigogenin-, hecogenin-, and diosgenin-beta-0-cellobioside heptaalkanoate from the relevant steroid in the presence of zinc fluoride or cyanide - Google Patents
Preparation of tigogenin-; 11-ketotigogenin-, hecogenin-, and diosgenin-beta-0-cellobioside heptaalkanoate from the relevant steroid in the presence of zinc fluoride or cyanideInfo
- Publication number
- NZ245244A NZ245244A NZ245244A NZ24524492A NZ245244A NZ 245244 A NZ245244 A NZ 245244A NZ 245244 A NZ245244 A NZ 245244A NZ 24524492 A NZ24524492 A NZ 24524492A NZ 245244 A NZ245244 A NZ 245244A
- Authority
- NZ
- New Zealand
- Prior art keywords
- tigogenin
- cellobioside
- zinc
- recited
- hecogenin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79757491A | 1991-11-25 | 1991-11-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ245244A true NZ245244A (en) | 1995-04-27 |
Family
ID=25171219
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ245244A NZ245244A (en) | 1991-11-25 | 1992-11-24 | Preparation of tigogenin-; 11-ketotigogenin-, hecogenin-, and diosgenin-beta-0-cellobioside heptaalkanoate from the relevant steroid in the presence of zinc fluoride or cyanide |
Country Status (13)
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2139104A1 (en) * | 1992-06-26 | 1994-01-06 | Michael P. Deninno | Steroidal glycosides for treating hypercholesterolemia |
| NZ252006A (en) * | 1992-06-26 | 1995-10-26 | Pfizer | Preparation of 1-o-steroidal peracyl-beta-glycosides |
| WO1994000478A1 (en) * | 1992-06-26 | 1994-01-06 | Pfizer Inc. | Steroidal beta-o-cellobioside heptaalkanoate process |
| EP0696292A1 (en) * | 1993-04-28 | 1996-02-14 | Pfizer Inc. | Spirostanyl glycosidal crystalline monohydrate |
| US5502038A (en) * | 1993-06-21 | 1996-03-26 | Medical Research Foundation Of Oregon | Cholesterol sequestrant glycosides that inhibit intestinal cholesterol absorption |
| EP0737202A1 (en) * | 1993-12-28 | 1996-10-16 | Pfizer Inc. | Hypocholesterolemic agents |
| US6150336A (en) * | 1995-05-29 | 2000-11-21 | Pfizer Inc. | Steroidal glycosides |
| US5756470A (en) * | 1996-10-29 | 1998-05-26 | Schering Corporation | Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents |
| US6982251B2 (en) | 2000-12-20 | 2006-01-03 | Schering Corporation | Substituted 2-azetidinones useful as hypocholesterolemic agents |
| SI1355644T1 (sl) | 2001-01-26 | 2006-10-31 | Schering Corp | Uporaba substituiranih azetidinonskih spojin za zdravljenje sitosterolemije |
| ES2290562T3 (es) | 2001-01-26 | 2008-02-16 | Schering Corporation | Combinaciones del activador del receptor activado por el proliferador de los peroxisomas (ppar) fenofibrato con el inhibidor de la absorcion de esteroles ezetimiba para indicaciones vasculares. |
| US7071181B2 (en) | 2001-01-26 | 2006-07-04 | Schering Corporation | Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors |
| US7056906B2 (en) | 2001-09-21 | 2006-06-06 | Schering Corporation | Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women |
| US7053080B2 (en) | 2001-09-21 | 2006-05-30 | Schering Corporation | Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors |
| PT1429756E (pt) | 2001-09-21 | 2007-01-31 | Schering Corp | Tratamento de xantoma com derivados de azetidinona como inibidores de absorção de esteróis |
| MXPA05004811A (es) | 2002-11-06 | 2005-07-22 | Schering Corp | Inhibidores de absorcion de colesterol para el tratamiento de trastornos autoinmunes. |
| ES2311806T3 (es) | 2003-03-07 | 2009-02-16 | Schering Corporation | Compuesto de azetidinona sustituidos, fornulaciones y usos de los mismos para el tratamiento de hipercolesterolemia. |
| US7459442B2 (en) | 2003-03-07 | 2008-12-02 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
| JP4589919B2 (ja) | 2003-03-07 | 2010-12-01 | シェーリング コーポレイション | 高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用 |
| WO2004081004A1 (en) | 2003-03-07 | 2004-09-23 | Schering Corporation | Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4602005A (en) * | 1982-05-17 | 1986-07-22 | Medical Research Foundation Of Oregon | Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis |
| US4602003A (en) * | 1982-05-17 | 1986-07-22 | Medical Research Foundation Of Oregon | Synthetic compounds to inhibit intestinal absorption of cholesterol in the treatment of hypercholesterolemia |
-
1992
- 1992-10-15 HU HU9401374A patent/HUT67035A/hu unknown
- 1992-10-15 FI FI942394A patent/FI942394A0/fi not_active Application Discontinuation
- 1992-10-15 EP EP92921860A patent/EP0619822A1/en not_active Withdrawn
- 1992-10-15 WO PCT/US1992/008638 patent/WO1993011150A1/en not_active Application Discontinuation
- 1992-10-15 CA CA002123684A patent/CA2123684A1/en not_active Abandoned
- 1992-10-15 JP JP5510090A patent/JPH0826064B2/ja not_active Expired - Lifetime
- 1992-10-15 AU AU27758/92A patent/AU659506B2/en not_active Ceased
- 1992-10-20 TW TW081108325A patent/TW232699B/zh active
- 1992-11-19 IL IL103797A patent/IL103797A0/xx unknown
- 1992-11-23 PT PT101088A patent/PT101088A/pt not_active Application Discontinuation
- 1992-11-24 ZA ZA929081A patent/ZA929081B/xx unknown
- 1992-11-24 MX MX9206761A patent/MX9206761A/es not_active IP Right Cessation
- 1992-11-24 NZ NZ245244A patent/NZ245244A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX9206761A (es) | 1995-01-31 |
| FI942394A7 (fi) | 1994-05-24 |
| FI942394L (fi) | 1994-05-24 |
| FI942394A0 (fi) | 1994-05-24 |
| HUT67035A (en) | 1995-01-30 |
| TW232699B (enrdf_load_stackoverflow) | 1994-10-21 |
| JPH06510794A (ja) | 1994-12-01 |
| JPH0826064B2 (ja) | 1996-03-13 |
| AU2775892A (en) | 1993-06-28 |
| IL103797A0 (en) | 1993-04-04 |
| ZA929081B (en) | 1994-05-24 |
| HU9401374D0 (en) | 1994-08-29 |
| PT101088A (pt) | 1994-02-28 |
| EP0619822A1 (en) | 1994-10-19 |
| CA2123684A1 (en) | 1993-06-10 |
| AU659506B2 (en) | 1995-05-18 |
| WO1993011150A1 (en) | 1993-06-10 |
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