JPH0657152B2 - Csf遺伝子類 - Google Patents

Csf遺伝子類

Info

Publication number
JPH0657152B2
JPH0657152B2 JP61166709A JP16670986A JPH0657152B2 JP H0657152 B2 JPH0657152 B2 JP H0657152B2 JP 61166709 A JP61166709 A JP 61166709A JP 16670986 A JP16670986 A JP 16670986A JP H0657152 B2 JPH0657152 B2 JP H0657152B2
Authority
JP
Japan
Prior art keywords
leu
ctg
ala
gln
cag
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP61166709A
Other languages
English (en)
Japanese (ja)
Other versions
JPS62236488A (ja
Inventor
達美 山崎
政幸 土屋
重一 長田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to PH34247A priority Critical patent/PH31057A/en
Priority to IE242786A priority patent/IE63992B1/en
Priority to NO863674A priority patent/NO179373C/no
Priority to CA000518286A priority patent/CA1341389C/en
Priority to DK198604432A priority patent/DK175336B1/da
Priority to HU863963A priority patent/HU209147B/hu
Priority to FI863757A priority patent/FI104982B/fi
Priority to AU62980/86A priority patent/AU598477C/en
Priority to KR1019860007835A priority patent/KR910005624B1/ko
Priority to IL80058A priority patent/IL80058A/xx
Priority to EP86113446A priority patent/EP0220520B1/en
Priority to AT86113446T priority patent/ATE67517T1/de
Priority to DE8686113446T priority patent/DE3681551D1/de
Publication of JPS62236488A publication Critical patent/JPS62236488A/ja
Priority to KR1019890006201A priority patent/KR920002312B1/ko
Priority to KR1019910019455A priority patent/KR920005752B1/ko
Priority to HR920628A priority patent/HRP920628B1/xx
Priority to SG650/93A priority patent/SG65093G/en
Priority to HK655/93A priority patent/HK65593A/en
Publication of JPH0657152B2 publication Critical patent/JPH0657152B2/ja
Priority to YU75295A priority patent/YU48523B/sh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
JP61166709A 1985-09-17 1986-07-17 Csf遺伝子類 Expired - Lifetime JPH0657152B2 (ja)

Priority Applications (19)

Application Number Priority Date Filing Date Title
PH34247A PH31057A (en) 1985-12-03 1986-09-11 Human granulocyte colony stimulating factor.
IE242786A IE63992B1 (en) 1985-09-17 1986-09-11 Human granulocyte colony stimulating factor
NO863674A NO179373C (no) 1985-09-17 1986-09-15 Rekombinant vektor istand til å uttrykke et glykoprotein, transformant som uttrykker et glykoprotein og fremgangsmåte for fremstilling av et glykoprotein
CA000518286A CA1341389C (en) 1985-09-17 1986-09-16 Human granulocyte colony stimulating factor
DK198604432A DK175336B1 (da) 1985-09-17 1986-09-16 DNA-sekvens, som koder for et peptid med granulocytstimulerende virkning, rekombinantvektor og transformant indeholdende denne sekvens, samt fremgangsmåde til fremstilling af polypeptidet
HU863963A HU209147B (en) 1985-09-17 1986-09-16 Method for producing stimulating factor of human granulocytae colony
FI863757A FI104982B (fi) 1985-09-17 1986-09-17 Menetelmä ihmisen granulosyyttipesäkkeitä stimuloivan tekijän valmistamiseksi, sitä koodittava geenisekvenssi, vektori ja isäntäsolu
AU62980/86A AU598477C (en) 1985-09-17 1986-09-17 Human granulocyte colony stimulating factor
KR1019860007835A KR910005624B1 (ko) 1985-09-17 1986-09-17 인체 과립성 백혈구의 콜로니 자극 인자 활성을 갖는 당단백질의 제조방법
IL80058A IL80058A (en) 1985-09-17 1986-09-17 Human granulocyte colony stimulating factor
AT86113446T ATE67517T1 (de) 1985-09-30 1986-09-30 Menschlicher granulozyten-colony stimulierender faktor.
EP86113446A EP0220520B1 (en) 1985-09-30 1986-09-30 Human granulocyte colony stimulating factor
DE8686113446T DE3681551D1 (de) 1985-09-30 1986-09-30 Menschlicher granulozyten-colony stimulierender faktor.
KR1019890006201A KR920002312B1 (ko) 1985-09-17 1989-05-09 인체 과립성 백혈구의 콜로니 자극인자
KR1019910019455A KR920005752B1 (ko) 1985-09-17 1991-11-01 인체 과립성 백혈구의 콜로니 자극인자
HR920628A HRP920628B1 (en) 1985-09-17 1992-09-30 Human granulocyte colony stimulating factor
SG650/93A SG65093G (en) 1985-09-30 1993-05-18 Human granulocyte colony stimulating factor
HK655/93A HK65593A (en) 1985-09-30 1993-07-08 Human granulocyte colony stimulating factor
YU75295A YU48523B (sh) 1985-09-30 1995-12-04 Faktor koji stimuliše humanu koloniju granulocita

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
JP60-206066 1985-09-17
JP20606685 1985-09-17
JP60-209638 1985-09-20
JP20963885 1985-09-20
JP60-217150 1985-09-30
JP21715085 1985-09-30
JP60-269456 1985-12-02
JP26945685 1985-12-02
JP27083985 1985-12-03
JP60-270839 1985-12-03

Publications (2)

Publication Number Publication Date
JPS62236488A JPS62236488A (ja) 1987-10-16
JPH0657152B2 true JPH0657152B2 (ja) 1994-08-03

Family

ID=27529395

Family Applications (4)

Application Number Title Priority Date Filing Date
JP61166709A Expired - Lifetime JPH0657152B2 (ja) 1985-09-17 1986-07-17 Csf遺伝子類
JP61166710A Granted JPS62236497A (ja) 1985-09-17 1986-07-17 顆粒球コロニー刺激因子活性を有する糖蛋白質の製造方法
JP63184486A Expired - Lifetime JPH0657156B2 (ja) 1985-09-17 1988-07-26 新糖蛋白質の製法
JP5183134A Expired - Lifetime JPH0783717B2 (ja) 1985-09-17 1993-06-30 ヒト顆粒球コロニー刺激因子をコードする遺伝子

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP61166710A Granted JPS62236497A (ja) 1985-09-17 1986-07-17 顆粒球コロニー刺激因子活性を有する糖蛋白質の製造方法
JP63184486A Expired - Lifetime JPH0657156B2 (ja) 1985-09-17 1988-07-26 新糖蛋白質の製法
JP5183134A Expired - Lifetime JPH0783717B2 (ja) 1985-09-17 1993-06-30 ヒト顆粒球コロニー刺激因子をコードする遺伝子

Country Status (1)

Country Link
JP (4) JPH0657152B2 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06102021B2 (ja) * 1985-12-03 1994-12-14 中外製薬株式会社 新規なポリペプチド
JPS63500636A (ja) * 1985-08-23 1988-03-10 麒麟麦酒株式会社 多分化能性顆粒球コロニー刺激因子をコードするdna
US4810643A (en) * 1985-08-23 1989-03-07 Kirin- Amgen Inc. Production of pluripotent granulocyte colony-stimulating factor
JPH0618779B2 (ja) * 1986-01-22 1994-03-16 中外製薬株式会社 造血機能回復促進剤
ZA872705B (en) * 1986-04-22 1987-10-05 Immunex Corporation Human g-csf protein expression
JP2989002B2 (ja) * 1988-12-22 1999-12-13 キリン―アムジエン・インコーポレーテツド 化学修飾顆粒球コロニー刺激因子
US6166183A (en) * 1992-11-30 2000-12-26 Kirin-Amgen, Inc. Chemically-modified G-CSF
US5505944A (en) * 1992-09-09 1996-04-09 Nippon Kayaku Kabushiki Kaisha Physiologically active substance NK175203, process for production thereof and pharmaceutical use thereof
US20030053982A1 (en) 1994-09-26 2003-03-20 Kinstler Olaf B. N-terminally chemically modified protein compositions and methods
US5824784A (en) 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
US6559322B1 (en) 2001-12-21 2003-05-06 Council Of Scientific And Industrial Research Process for preparation of a lactone from a cyclic ketone
CN105131104B (zh) 2001-10-10 2018-11-16 诺和诺德公司 肽的重构和糖缀合
WO2010131382A1 (ja) 2009-05-14 2010-11-18 Fukuda Keiichi 筋肉修復促進剤
WO2012067262A1 (ja) 2010-11-17 2012-05-24 Fukuda Keiichi 筋ジストロフィー治療剤
WO2017072880A1 (ja) * 2015-10-28 2017-05-04 三菱重工コンプレッサ株式会社 弁装置、蒸気タービン設備

Also Published As

Publication number Publication date
JPH025395B2 (da) 1990-02-01
JPH0783717B2 (ja) 1995-09-13
JPH0657156B2 (ja) 1994-08-03
JPS62236497A (ja) 1987-10-16
JPS6485098A (en) 1989-03-30
JPH06339381A (ja) 1994-12-13
JPS62236488A (ja) 1987-10-16

Similar Documents

Publication Publication Date Title
AU599572B2 (en) Lymphokine production and purification
EP0220520B1 (en) Human granulocyte colony stimulating factor
JPH0693000A (ja) エリスロポエチン
JPH0657152B2 (ja) Csf遺伝子類
HK1060146A (en) Methods for preparing human thrombopoietin polypeptides by mammalian cell cultures
CN1020473C (zh) 编码表现有人粒性巨噬细胞和嗜伊红细胞生长因子活性之多肽的cDNA克隆
US5908763A (en) DNA encoding GM-CSF and a method of producing GM-CSF protein
JPH0618778B2 (ja) 白血球減少症治療剤
JPS63159399A (ja) B細胞刺激因子
CZ289498A3 (cs) Rekombinantní bílkovina GM-CSF lidí a farmaceutický prostředek, který ji obsahuje
US5151349A (en) Method for expressing polypeptide having anti-tumor activity
JPH06102021B2 (ja) 新規なポリペプチド
KR920002312B1 (ko) 인체 과립성 백혈구의 콜로니 자극인자
RU2057809C1 (ru) Способ получения фактора, стимулирующего образование колоний гранулоцитов
WO1986002100A1 (en) Vectors containing a gene for a protein having erythroid-potentiating activity and recombinant dna methods for producing said protein
KR920005752B1 (ko) 인체 과립성 백혈구의 콜로니 자극인자
JPH07163390A (ja) 新規なポリペプチドの製造法
HU209147B (en) Method for producing stimulating factor of human granulocytae colony
JPH089640B2 (ja) ヒト・インターロイキン−2受容体
HK1011709B (en) Lymphokine production and purification

Legal Events

Date Code Title Description
EXPY Cancellation because of completion of term