JPH0553505B2 - - Google Patents

Info

Publication number
JPH0553505B2
JPH0553505B2 JP2246000A JP24600090A JPH0553505B2 JP H0553505 B2 JPH0553505 B2 JP H0553505B2 JP 2246000 A JP2246000 A JP 2246000A JP 24600090 A JP24600090 A JP 24600090A JP H0553505 B2 JPH0553505 B2 JP H0553505B2
Authority
JP
Japan
Prior art keywords
tissue
collagen
gel
tissue equivalent
container
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2246000A
Other languages
English (en)
Japanese (ja)
Other versions
JPH03151977A (ja
Inventor
Deibitsudo Kenpu Hooru
Beru Yuujiin
Teii Keigan Deibitsudo
Meison Barerii
Kabaraaro Jon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OOGANOJENESHISU Inc
Original Assignee
OOGANOJENESHISU Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by OOGANOJENESHISU Inc filed Critical OOGANOJENESHISU Inc
Publication of JPH03151977A publication Critical patent/JPH03151977A/ja
Publication of JPH0553505B2 publication Critical patent/JPH0553505B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698—Skin equivalents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C12M25/04—Membranes; Filters in combination with well or multiwell plates, i.e. culture inserts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323—Adult fibroblasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Sustainable Development (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
JP2246000A 1989-09-15 1990-09-14 生組織等価物 Granted JPH03151977A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40805289A 1989-09-15 1989-09-15
US408,052 1989-09-15

Publications (2)

Publication Number Publication Date
JPH03151977A JPH03151977A (ja) 1991-06-28
JPH0553505B2 true JPH0553505B2 (cg-RX-API-DMAC7.html) 1993-08-10

Family

ID=23614662

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2246000A Granted JPH03151977A (ja) 1989-09-15 1990-09-14 生組織等価物

Country Status (12)

Country Link
US (1) US5536656A (cg-RX-API-DMAC7.html)
EP (1) EP0418035B1 (cg-RX-API-DMAC7.html)
JP (1) JPH03151977A (cg-RX-API-DMAC7.html)
KR (1) KR940001379B1 (cg-RX-API-DMAC7.html)
AT (1) ATE119194T1 (cg-RX-API-DMAC7.html)
AU (1) AU6215690A (cg-RX-API-DMAC7.html)
CA (2) CA2023968C (cg-RX-API-DMAC7.html)
DE (1) DE69017324T2 (cg-RX-API-DMAC7.html)
DK (1) DK0418035T3 (cg-RX-API-DMAC7.html)
ES (1) ES2071778T3 (cg-RX-API-DMAC7.html)
IE (1) IE903340A1 (cg-RX-API-DMAC7.html)
IL (1) IL95429A (cg-RX-API-DMAC7.html)

Families Citing this family (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5888720A (en) * 1992-10-27 1999-03-30 Yissum Research And Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs
CA2119064A1 (en) * 1993-03-17 1994-09-18 Richard A. Berg Dermal-epidermal in vitro test system
GB9306449D0 (en) * 1993-03-29 1993-05-19 Nat Heart Research Fund Tissue equivalents
US5693085A (en) 1994-04-29 1997-12-02 Scimed Life Systems, Inc. Stent with collagen
US5665114A (en) * 1994-08-12 1997-09-09 Meadox Medicals, Inc. Tubular expanded polytetrafluoroethylene implantable prostheses
US5891558A (en) * 1994-11-22 1999-04-06 Tissue Engineering, Inc. Biopolymer foams for use in tissue repair and reconstruction
US6419920B1 (en) 1995-10-25 2002-07-16 Trans Karyotic Therapies, Inc. Hybrid matrix implants and explants
US5965125A (en) 1995-10-25 1999-10-12 Transkaryotic Therapies, Inc. Hybrid matrix implants and explants
US5955353A (en) * 1997-05-22 1999-09-21 Excorp Medical, Inc. Hollow fiber bioreactor with an extrafilament flow plug
US20020086423A1 (en) * 1997-09-09 2002-07-04 Toshiaki Takezawa Hydrogel thin film containing extracellular matrix components
US6498138B1 (en) 1998-03-11 2002-12-24 University Of Southern California Method of promoting production of living tissue equivalents
US6129757A (en) * 1998-05-18 2000-10-10 Scimed Life Systems Implantable members for receiving therapeutically useful compositions
ES2402739T3 (es) 1998-11-19 2013-05-08 Organogenesis Inc. Constructos tisulares modificados por bioingeniería y métodos para producirlos y utilizarlos
US7001746B1 (en) * 1999-01-29 2006-02-21 Artecel Sciences, Inc. Methods and compositions for the differentiation of human preadipocytes into adipocytes
WO2000047129A2 (en) * 1999-02-11 2000-08-17 The General Hospital Corporation Microfabricated membranes and matrices
US6197061B1 (en) * 1999-03-01 2001-03-06 Koichi Masuda In vitro production of transplantable cartilage tissue cohesive cartilage produced thereby, and method for the surgical repair of cartilage damage
DE60036385T2 (de) 1999-06-21 2008-06-26 The General Hospital Corp., Boston Zellkultursysteme und verfahren für einrichtungen zur organunterstützung
AU7067200A (en) * 1999-08-23 2001-03-19 Organogenesis Inc. Skin care compositions and treatments
US7078230B2 (en) 2000-02-26 2006-07-18 Artecel, Inc. Adipose tissue-derived stromal cell that expresses characteristics of a neuronal cell
US7582292B2 (en) 2000-02-26 2009-09-01 Artecel, Inc. Adipose tissue derived stromal cells for the treatment of neurological disorders
EP1918366A1 (en) 2000-02-26 2008-05-07 Artecel, Inc. Pleuripotent stem cells generated from adipose tissue-derived stromal cells and uses thereof
ATE308610T1 (de) 2000-05-31 2005-11-15 Fraunhofer Ges Forschung Dreidimensionales hautmodell
CA2410946A1 (en) * 2000-05-31 2002-11-29 Fraunhofer-Gesellschaft Zur Forderung Der Angewandten Forschung E.V. In vitro tissue test system
US7144729B2 (en) 2000-09-01 2006-12-05 Dfb Pharmaceuticals, Inc. Methods and compositions for tissue regeneration
EP1832300A3 (en) * 2000-09-18 2008-02-27 Organogenesis Inc. Method for treating a patient using a cultured connective tissue construct
ATE364410T1 (de) 2000-09-18 2007-07-15 Organogenesis Inc Verfahren zur behandlung eines patienten mit einem kultivierten bindegewebe-konstrukt
US7041868B2 (en) 2000-12-29 2006-05-09 Kimberly-Clark Worldwide, Inc. Bioabsorbable wound dressing
US6974697B2 (en) * 2001-03-02 2005-12-13 Stratech Corporation Skin substitutes with improved barrier function
EP1404809B1 (en) * 2001-03-02 2013-12-11 Stratatech Corporation Improved skin substitutes and uses thereof
US20030211793A1 (en) * 2001-03-05 2003-11-13 Eugene Bell Injectable bio-compatible material and methods of use
JP3960969B2 (ja) 2001-06-14 2007-08-15 ミリポア・コーポレイション 突出部を備えるトレイ
EP1435980A4 (en) * 2001-09-15 2006-06-07 Univ California LAMINATED CARTILAGINOUS FABRIC AND MANUFACTURING METHOD THEREOF
US20030165473A1 (en) * 2001-11-09 2003-09-04 Rush-Presbyterian-St. Luke's Medical Center Engineered intervertebral disc tissue
WO2003072128A2 (en) * 2002-02-22 2003-09-04 Ebi, L.P. Methods and compositions for treating bone or cartilage defects
US7741116B2 (en) 2002-03-06 2010-06-22 University Of Cincinnati Surgical device for skin therapy or testing
CA2483547C (en) * 2002-04-30 2012-03-20 Stratatech Corporation Keratinocytes expressing exogenous angiogenic growth factors
US7229820B2 (en) * 2002-06-13 2007-06-12 Wilson Wolf Manufacturing Corporation Apparatus and method for culturing and preserving tissue constructs
WO2004013606A2 (en) 2002-08-02 2004-02-12 Stratatech Corporation Species specific dna detection
JP4734245B2 (ja) 2003-08-01 2011-07-27 ストラタテック コーポレーション 外因性ポリペプチドを発現するヒト皮膚等価物
FR2881434B1 (fr) * 2005-02-02 2007-05-11 Coletica Sa Dispositif de support de culture de cellules
JP4993752B2 (ja) 2005-03-01 2012-08-08 ストラタテック コーポレーション 外因性ポリペプチドを発現するヒト皮膚同等物
JP2008532550A (ja) 2005-03-17 2008-08-21 ストラタテック コーポレーション 純度が改良された代用皮膚
FR2889808B1 (fr) 2005-08-17 2011-07-22 Oreal Utilisation de l'acide 8-hexadecene-1,16-dicarboxylique comme agent de soin destine a favoriser la cohesion de la couche cornee
MX2008011287A (es) * 2006-03-03 2008-11-14 Organogenesis Inc Regeneracion y reparacion de tejido oral.
FR2903702B1 (fr) * 2006-07-13 2012-10-19 Oreal Equivalent d'epiderme capable de se pigmenter obtenu a partir de cellules de la matrice, procede de preparation et utilisation
US8932619B2 (en) * 2007-06-27 2015-01-13 Sofradim Production Dural repair material
US20090068250A1 (en) 2007-09-07 2009-03-12 Philippe Gravagna Bioresorbable and biocompatible compounds for surgical use
US20100278798A1 (en) * 2007-09-27 2010-11-04 The Trustees Of Columbia University In The City Of New York Methods and systems for forming biocompatible materials
WO2009065005A1 (en) 2007-11-14 2009-05-22 Stratatech Corporation Cold storage of organotypically cultured skin equivalents for clinical applications
US9308068B2 (en) 2007-12-03 2016-04-12 Sofradim Production Implant for parastomal hernia
PL2288376T3 (pl) 2008-04-18 2016-07-29 Collplant Ltd Sposoby generowania i wykorzystywania prokolagenu
WO2009156866A2 (en) 2008-06-27 2009-12-30 Sofradim Production Biosynthetic implant for soft tissue repair
EP2350259A4 (en) * 2008-10-22 2013-12-18 Regenemed Inc CULTURE SYSTEMS
CN102271634B (zh) 2008-11-04 2015-01-14 斯特拉塔特克公司 即用型经干燥和经辐照的皮肤等同物
WO2010111278A1 (en) 2009-03-23 2010-09-30 The Texas A&M University System Compositions of mesenchymal stem cells to regenerate bone
WO2010135655A2 (en) 2009-05-21 2010-11-25 Stratatech Corporation Human skin substitutes expressing il-12
US9321988B2 (en) * 2009-06-18 2016-04-26 Illinois Tool Works Inc. Gas and liquid tissue culture interface
FR2949688B1 (fr) 2009-09-04 2012-08-24 Sofradim Production Tissu avec picots revetu d'une couche microporeuse bioresorbable
SG184385A1 (en) * 2010-04-05 2012-11-29 Emd Millipore Corp Polymeric membranes with human skin like permeability properties and uses thereof
FR2967163A1 (fr) 2010-11-05 2012-05-11 Centre Nat Rech Scient Procede in vitro ou ex vivo pour la maintenance en survie et la generation ou reconstruction d'un epiderme
FR2972626B1 (fr) 2011-03-16 2014-04-11 Sofradim Production Prothese comprenant un tricot tridimensionnel et ajoure
FR2976001B1 (fr) 2011-05-30 2014-10-31 Oreal Modele de cuir chevelu reconstruit et procede de screening de molecules actives
FR2977789B1 (fr) 2011-07-13 2013-07-19 Sofradim Production Prothese pour hernie ombilicale
FR2977790B1 (fr) 2011-07-13 2013-07-19 Sofradim Production Prothese pour hernie ombilicale
US9867909B2 (en) 2011-09-30 2018-01-16 Sofradim Production Multilayer implants for delivery of therapeutic agents
WO2013046058A2 (en) 2011-09-30 2013-04-04 Sofradim Production Reversible stiffening of light weight mesh
FR2985170B1 (fr) 2011-12-29 2014-01-24 Sofradim Production Prothese pour hernie inguinale
FR2985271B1 (fr) 2011-12-29 2014-01-24 Sofradim Production Tricot a picots
FR2994185B1 (fr) 2012-08-02 2015-07-31 Sofradim Production Procede de preparation d’une couche poreuse a base de chitosane
PL226837B1 (pl) 2012-08-24 2017-09-29 Celther Polska Spółka Z Ograniczoną Odpowiedzialnością Aktywna warstwa polimerowa utworzona zpochodnych chityny zwłaszcza doopatrunku oraz jejzastosowanie
FR2995779B1 (fr) 2012-09-25 2015-09-25 Sofradim Production Prothese comprenant un treillis et un moyen de consolidation
FR2995788B1 (fr) 2012-09-25 2014-09-26 Sofradim Production Patch hemostatique et procede de preparation
FR2995778B1 (fr) 2012-09-25 2015-06-26 Sofradim Production Prothese de renfort de la paroi abdominale et procede de fabrication
AU2013322268B2 (en) 2012-09-28 2017-08-31 Sofradim Production Packaging for a hernia repair device
USD692160S1 (en) 2012-10-26 2013-10-22 Paragonix Technologies, Inc. Tissue suspension adaptor
WO2014160000A1 (en) 2013-03-13 2014-10-02 Stratatech Corporation Cryopreservation of viable human skin substitutes
AU2014259787B2 (en) 2013-05-03 2018-03-08 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Skin substitutes and methods for hair follicle neogenesis
FR3006578B1 (fr) 2013-06-07 2015-05-29 Sofradim Production Prothese a base d’un textile pour voie laparoscopique
FR3006581B1 (fr) 2013-06-07 2016-07-22 Sofradim Production Prothese a base d’un textile pour voie laparoscopique
WO2015166455A1 (en) 2014-04-30 2015-11-05 Fondazione Istituto Italiano Di Tecnologia Method for producing a totally endogenous bioengineered tissue and tissue obtained thereby
EP3000489B1 (en) 2014-09-24 2017-04-05 Sofradim Production Method for preparing an anti-adhesion barrier film
EP3000432B1 (en) 2014-09-29 2022-05-04 Sofradim Production Textile-based prosthesis for treatment of inguinal hernia
EP3000433B1 (en) 2014-09-29 2022-09-21 Sofradim Production Device for introducing a prosthesis for hernia treatment into an incision and flexible textile based prosthesis
EP3029189B1 (en) 2014-12-05 2021-08-11 Sofradim Production Prosthetic porous knit, method of making same and hernia prosthesis
EP3059255B1 (en) 2015-02-17 2020-05-13 Sofradim Production Method for preparing a chitosan-based matrix comprising a fiber reinforcement member
EP3085337B1 (en) 2015-04-24 2022-09-14 Sofradim Production Prosthesis for supporting a breast structure
EP3106185B1 (en) 2015-06-19 2018-04-25 Sofradim Production Synthetic prosthesis comprising a knit and a non porous film and method for forming same
EP3195830B1 (en) 2016-01-25 2020-11-18 Sofradim Production Prosthesis for hernia repair
FR3054449B1 (fr) 2016-07-29 2018-08-31 L'oreal Equivalent de peau a compartiments dermiques juxtaposes distincts
EP3312325B1 (en) 2016-10-21 2021-09-22 Sofradim Production Method for forming a mesh having a barbed suture attached thereto and the mesh thus obtained
EP3398554B1 (en) 2017-05-02 2025-06-25 Sofradim Production Prosthesis for inguinal hernia repair
WO2018220137A1 (en) * 2017-05-31 2018-12-06 ETH Zürich Assembly for the production of tissue implants
FR3071512B1 (fr) 2017-09-28 2022-02-25 Oreal Signatures moleculaires de trois sous-populations de fibroblastes dermiques et equivalent de derme comprenant une de ces sous-populations
EP3653171B1 (en) 2018-11-16 2024-08-21 Sofradim Production Implants suitable for soft tissue repair
US12064330B2 (en) 2020-04-28 2024-08-20 Covidien Lp Implantable prothesis for minimally invasive hernia repair
FR3111904B1 (fr) 2020-06-30 2022-10-21 Oreal Bioencre pour bioimpression d’un modèle de jonction dermo-épidermique invaginée
US12435312B2 (en) 2022-02-28 2025-10-07 Brown University Quantifying cell-derived changes in collagen synthesis, alignment, and mechanics in a 3D connective tissue model
LU502391B1 (en) 2022-06-28 2024-01-09 Univerza V Mariboru A complex in vitro model of human skin, a process for preparation and use thereof

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2677646A (en) * 1952-03-22 1954-05-04 Lovell Chemical Company Unit for bacterial analysis
US2761813A (en) * 1953-01-21 1956-09-04 Goetz Alexander Means and method of producing and controlling cultures of microorganisms
GB1594389A (en) * 1977-06-03 1981-07-30 Max Planck Gesellschaft Dressing material for wounds
JPS6133593B2 (cg-RX-API-DMAC7.html) * 1978-12-26 1986-08-02 Massachusetts Inst Technology
US4290911A (en) * 1979-02-07 1981-09-22 Fmc Corporation Agarose composition, aqueous gel and method of making same
SE7908454L (sv) * 1979-10-11 1981-04-12 Pharmacia Fine Chemicals Ab Medium for isoelektrisk fokusering
US4539716A (en) * 1981-03-19 1985-09-10 Massachusetts Institute Of Technology Fabrication of living blood vessels and glandular tissues
US4546500A (en) * 1981-05-08 1985-10-15 Massachusetts Institute Of Technology Fabrication of living blood vessels and glandular tissues
US4505266A (en) * 1981-10-26 1985-03-19 Massachusetts Institute Of Technology Method of using a fibrous lattice
US4485096A (en) * 1982-02-26 1984-11-27 Massachusetts Institute Of Technology Tissue-equivalent and method for preparation thereof
US4485097A (en) * 1982-05-26 1984-11-27 Massachusetts Institute Of Technology Bone-equivalent and method for preparation thereof
US4598045A (en) * 1982-08-25 1986-07-01 Hana Biologics, Inc. Triphasic mycoplasmatales detection method
US4734372A (en) * 1983-02-04 1988-03-29 Brown University Research Foundation Cell culturing methods and apparatus
US4578354A (en) * 1983-05-09 1986-03-25 Pfizer Inc. Immobilization of catalytically active microorganisms in agar gel fibers
EP0164583B1 (en) * 1984-05-11 1991-09-25 TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION Method for manufacture a container made of synthetic resin
US4604346A (en) * 1984-10-09 1986-08-05 Massachusetts Institute Of Technology Skin-equivalent prepared by the use of punch biopsy
JPS6225974A (ja) * 1985-07-25 1987-02-03 Asahi Chem Ind Co Ltd コラ−ゲンよりなるゲル状組成物
US5026649A (en) * 1986-03-20 1991-06-25 Costar Corporation Apparatus for growing tissue cultures in vitro
US5032508A (en) * 1988-09-08 1991-07-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US4963489A (en) * 1987-04-14 1990-10-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
US5037656A (en) * 1986-12-04 1991-08-06 Millipore Corporation Porous membrane having hydrophilic and cell growth promotions surface and process
FR2612938B1 (fr) * 1987-03-26 1989-06-23 Cird Procede d'obtention d'un equivalent de peau et equivalent de peau correspondant
FR2612939B1 (fr) * 1987-03-26 1989-06-23 Cird Equivalent de peau
US4835102A (en) * 1987-03-31 1989-05-30 Eugene Bell Tissue equivalent test systems
US4837379A (en) * 1988-06-02 1989-06-06 Organogenesis Inc. Fibrin-collagen tissue equivalents and methods for preparation thereof
US4996154A (en) * 1989-05-04 1991-02-26 Millipore Corporation Method for growing cellular tissue
US4912057A (en) * 1989-06-13 1990-03-27 Cancer Diagnostics, Inc. Cell chamber for chemotaxis assay

Also Published As

Publication number Publication date
CA2298856C (en) 2004-11-16
KR940001379B1 (ko) 1994-02-21
CA2023968A1 (en) 1991-03-16
CA2298856A1 (en) 1991-03-16
ATE119194T1 (de) 1995-03-15
EP0418035A1 (en) 1991-03-20
EP0418035B1 (en) 1995-03-01
US5536656A (en) 1996-07-16
IL95429A0 (en) 1991-06-30
DK0418035T3 (da) 1995-07-10
KR910005893A (ko) 1991-04-27
DE69017324T2 (de) 1995-08-03
CA2023968C (en) 2000-05-02
AU6215690A (en) 1991-08-01
ES2071778T3 (es) 1995-07-01
JPH03151977A (ja) 1991-06-28
DE69017324D1 (de) 1995-04-06
IL95429A (en) 1997-09-30
IE903340A1 (en) 1991-04-10

Similar Documents

Publication Publication Date Title
JPH0553505B2 (cg-RX-API-DMAC7.html)
EP2639293B1 (en) Cell culture chamber, method for producing same, tissue model using cell culture chamber, and method for producing same
EP0793511B1 (en) Biopolymer foams having extracellular matrix particulates
US6040493A (en) Bioreactor wound dressing
EP0684309B1 (en) Cell culture substrates and methods of use
JPH05506169A (ja) 合成生体皮膚等価物
CA2065432A1 (en) Cell culture products
US5077215A (en) Neutralized perfluoro-3,6-dioxa-4-methyl-7-octene sulphonyl fluoride copolymer surface for attachment and growth of animal cells
WO2005014774A1 (ja) 動物細胞の培養担体と、該培養担体を用いた動物細胞の培養方法および移植方法
US8013121B2 (en) Isolated nature-identical collagen
JP3951148B2 (ja) 皮膚付属器官様構造体を含む人工皮膚及びその製造方法
Chin et al. A microfabricated porous collagen-based scaffold as prototype for skin substitutes
JP3738273B2 (ja) 改良ケラチノサイト培養物およびその使用
CN109722410B (zh) 一种3d全层皮肤模型及用于其形成的培养基、制备方法
US6043079A (en) Cell growth apparatus for histophysiologic culture
Malik et al. Organ, histotypic and organotypic culture, and tissue engineering
EP3967748A1 (en) Nanocellulose 3d matrix for cultivating human and animal cells in vitro
Na et al. Fabrication of a Contraction-Free Full-Thickness Human Skin Equivalent Using Skin-on-a-Chip with Silk Fibroin Scaffold
CN106119108B (zh) 双层流动腔系统力学微环境下HSCs与EPCs分层共培养工具和方法
JP2015223108A (ja) 細胞培養チャンバーとその製造方法、細胞培養チャンバーを利用した細胞培養方法および細胞培養キット
JP2007053906A (ja) 三次元培養物の精製方法及び精製された三次元培養物
Plant et al. Schwann cell transplantation methods using biomaterials
Leighton Radial histophysiologic gradient culture chamber: rationale and preparation
JPH07170971A (ja) 組織切片培養用基盤
Vojtaššák et al. In vitro cytotoxicity testing of coladerm membrane

Legal Events

Date Code Title Description
R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20080810

Year of fee payment: 15

LAPS Cancellation because of no payment of annual fees